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Efficacy of Repetitive Transcranial Magnetic Stimulation Combined With Visual Scanning Treatment on Cognitive-Behavioral Symptoms of Unilateral Spatial Neglect in Patients With Traumatic Brain Injury: Study Protocol for a Randomized Controlled Trial.

Front Neurol 2021 14;12:702649. Epub 2021 Jul 14.

IRCCS, Istituto delle Scienze Neurologiche di Bologna, UO di Medicina Riabilitativa e Neuroriabilitazione, Bologna, Italy.

Left hemispatial neglect (LHSN) is a frequent and disabling condition affecting patients who suffered from traumatic brain injury (TBI). LHSN is a neuropsychological syndrome characterized clinically by difficulties in attending, responding, and consciously representing the right side of space. Despite its frequency, scientific evidence on effective treatments for this condition in TBI patients is still low. Read More

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Mid-term results of total hip arthroplasty with subtrochanteric Z-osteotomy in Crowe type 3-4 developmental hip dysplasia.

Turk J Med Sci 2021 Aug 2. Epub 2021 Aug 2.

Background/aim: Total hip arthroplasty (THA) is technically more difficult and has higher complication rates in patients with Crowe type 3-4 developmental dysplasia of the hip (DDH). Due to the difficulties and different treatment options, there is still no consensus on the optimal treatment. We aimed to evaluate the mid-term results of our patients who had undergone subtrochanteric femoral shortening Z-osteotomy. Read More

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Neurodevelopmental Profile in Children Affected by Ocular Albinism.

Neuropediatrics 2021 Jul 29. Epub 2021 Jul 29.

Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy.

Aim:  The aim of this study was to detail the neurodevelopmental profile of subjects affected by ocular albinism (OA) and to collect data on GPR143 gene analysis.

Design:  The design of the study involves a retrospective longitudinal observational case series.

Methods:  We collected data on the neurodevelopmental profile of 13 children affected by OA from clinical annual assessments conducted for a period of 6 years after the first evaluation. Read More

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Necrotizing Enterocolitis in Neonates: Has the Brain Taken a Hit 10 Years Later?

J Pediatr Neurosci 2021 Jan-Mar;16(1):30-34. Epub 2021 Jun 25.

Royal London Hospital, London, UK.

Background: The neonate with necrotizing enterocolitis (NEC) is at risk of developing poor neurodevelopmental outcomes. There is a dearth of long-term follow-up studies in this field, with a majority of studies reporting a follow-up duration of 2 years. The aim of this study was to assess neurodevelopment of babies diagnosed with NEC more than a decade ago. Read More

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Parental experiences with their child's eating disorder treatment journey.

J Eat Disord 2021 Jul 27;9(1):92. Epub 2021 Jul 27.

Department of Psychiatry, University of British Columbia, Vancouver, BC, Canada.

Background: Parents are integral in the treatment of pediatric eating disorders. The current study was conducted to further understand the barriers and facilitators that parents experience in accessing specialized, tertiary level eating disorder treatment for children and adolescents. The goals of the study were to understand the processes leading to diagnosis and treatment, perceived barriers and facilitators to accessing care, and parents' experiences over the course of their child's eating disorder treatment. Read More

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Discriminative Cervical Lesion Detection in Colposcopic Images with Global Class Activation and Local Bin Excitation.

IEEE J Biomed Health Inform 2021 Jul 27;PP. Epub 2021 Jul 27.

Accurate cervical lesion detection (CLD) methods using colposcopic images are highly demanded in computer-aided diagnosis (CAD) for automatic diagnosis of High-grade Squamous Intraepithelial Lesions (HSIL). However, compared to natural scene images, the specific characteristics of colposcopic images, such as low contrast, visual similarity, and ambiguous lesion boundaries, pose difficulties to accurately locating HSIL regions and also significantly impede the performance improvement of existing CLD approaches. To tackle these difficulties and better capture cervical lesions, we develop novel feature enhancing mechanisms from both global and local perspectives, and propose a new discriminative CLD framework, called CervixNet, with a Global Class Activation (GCA) module and a Local Bin Excitation (LBE) module. Read More

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Variability in Neuropsychological Phenotypes in Patients with 22Q11.2 Deletion Syndrome: Case Series.

Dev Neuropsychol 2021 Jul 27:1-12. Epub 2021 Jul 27.

Center for Advanced Heart and Lung Disease, Baylor University Medical Center, Dallas, TX.

Children with 22q11.2 deletion syndrome (22q11.2DS) have diverse neurodevelopmental and mental health profiles involving cognitive impairments and behavioral symptomatology that evolve over the lifespan. Read More

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Problems in Malaysian children with large angle infantile esotropia: Children and parents' perspectives.

Med J Malaysia 2021 Jul;76(4):526-533

Universiti Sains Malaysia, School of Medical Sciences, Department of Ophthalmology and Visual Science, Kubang Kerian, Kelantan, Malaysia.

Introduction: There is limited information regarding the problems faced by children with large angle infantile esotropia (LAIE). The aim of this study was to explore the problems that children with LAIE encounter from both their perspectives and those of their parents.

Methods: This study included children who had LAIE (with angle of 40 prism dioptres or greater), aged 5 and 17 years who had attended the Ophthalmology Clinic, Hospital Universiti Sains Malaysia from March to September 2016. Read More

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Perceptual visual dysfunction in children - An Indian perspective.

Indian J Ophthalmol 2021 08;69(8):2004-2011

Department of Vision Science, Glasgow Caledonian University, Glasgow, United Kingdom.

Perceptual visual dysfunction (PVD) comprises a group of vision disorders resulting from dysfunction of the posterior parietal and/or temporal lobes. Often, affected children have normal/near normal visual acuities and/or visual fields, but have difficulties in activities of daily living involving the use of vision. PVDs are known to be common among children with risk factors such as a history of prematurity and/or neurodevelopmental disorders. Read More

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Developmental brain dynamics of numerical and arithmetic abilities.

NPJ Sci Learn 2021 Jul 23;6(1):22. Epub 2021 Jul 23.

Faculty of Psychology and Educational Sciences, KU Leuven, University of Leuven, Leuven, Belgium.

The development of numerical and arithmetic abilities constitutes a crucial cornerstone in our modern and educated societies. Difficulties to acquire these central skills can lead to severe consequences for an individual's well-being and nation's economy. In the present review, we describe our current broad understanding of the functional and structural brain organization that supports the development of numbers and arithmetic. Read More

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Impact of Prajñā yoga on cognition in adolescents with congenital and adventitious visual impairment.

Explore (NY) 2021 Jul 5. Epub 2021 Jul 5.

Sri Sri Institute for Advanced Research, Bangalore, India.

Context: Numerous scientific studies have investigated the impact of yoga on cognition in children and adults. However, fewer studies have assessed the impact of yogic practices on cognition in children and adolescents with visual impairment. Despite their keen intellectual abilities and advanced linguistic skills, teens with visual impairment often experience difficulties with cognitive control and behavioral regulation. Read More

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[A rare case of a functioning gonadotroph tumor accompanied by erythrocytosis in an elderly man].

Probl Endokrinol (Mosk) 2021 Jun 13;67(3):37-44. Epub 2021 Jun 13.

Endocrinology Research Center.

Functioning gonadotroph adenomas are rare pituitary tumors secreting one or two gonadotropins (follicle-stimulating hormone (FSH) and/or luteinizing hormone (LH)), which are hormonally active. In the majority of cases, gonadotroph tumors are endocrinologically "silent" and make up more than a half of non-functioning pituitary adenomas. In this article we describe a rare clinical case of LH/FSH-secreting pituitary macroadenoma with bitemporal hemianopsia in a 62-year-old man. Read More

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Behavioral and Neural Signatures of Visual Imagery Vividness Extremes: Aphantasia versus Hyperphantasia.

Cereb Cortex Commun 2021 5;2(2):tgab035. Epub 2021 May 5.

Cognitive Neurology Research Group, University of Exeter Medical School, College House, Exeter EX1 2LU, UK.

Although Galton recognized in the 1880s that some individuals lack visual imagery, this phenomenon was mostly neglected over the following century. We recently coined the terms "aphantasia" and "hyperphantasia" to describe visual imagery vividness extremes, unlocking a sustained surge of public interest. Aphantasia is associated with subjective impairment of face recognition and autobiographical memory. Read More

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Visual Performances of a New Extended Depth-of-Focus Intraocular Lens with a Refractive Design: A Prospective Study After Bilateral Implantation.

Ther Clin Risk Manag 2021 16;17:727-738. Epub 2021 Jul 16.

Eye Clinic, Policlinico Umberto 1, "Sapienza" University of Rome, Rome, Italy.

Purpose: The aim of the present study was to evaluate the visual outcome of a new extended depth-of-focus (EDOF) intraocular lens (IOL) after bilateral implantation. A qualitative and quantitative analysis was performed and data were compared with those given by other studies regarding multifocal IOLs, which have the same purpose of giving spectacle independence to the patients.

Methods: The study enrolled 40 eyes of 20 patients who underwent cataract surgery with bilateral implantation of an EDOF IOL (Evolve Soleko, Rome, Italy). Read More

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Chronic stress and poor sleeping habits are associated with self-reported IBS and poor psychological well-being in the general population.

BMC Res Notes 2021 Jul 22;14(1):280. Epub 2021 Jul 22.

Department of Internal Medicine, Lund University, Skåne University Hospital, Jan Waldenström Street 15, Floor 5, 20502, Malmö, Sweden.

Objective: The present population-based study aimed to examine the association of chronic stress and sleeping difficulties with self-reported irritable bowel syndrome (IBS), gastrointestinal (GI) symptoms past 2 weeks, and psychological well-being.

Results: The Malmö Offspring Study included subjects from the general population to complete a questionnaire regarding sociodemographic factors, lifestyle factors, and medical health. Experience of chronic stress during the past or past 5 years was reported. Read More

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Simulating Visibility and Reading Performance in Low Vision.

Front Neurosci 2021 5;15:671121. Epub 2021 Jul 5.

Department of Psychology, University of Minnesota, Minneapolis, MN, United States.

Purpose: Low vision reduces text visibility and causes difficulties in reading. A valid low-vision simulation could be used to evaluate the accessibility of digital text for readers with low vision. We examined the validity of a digital simulation for replicating the text visibility and reading performance of low-vision individuals. Read More

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The brain basis of handwriting deficits in Chinese children with developmental dyslexia.

Dev Sci 2021 Jul 20. Epub 2021 Jul 20.

Center for Brain Disorders and Cognitive Sciences, Shenzhen University, Shenzhen, 518060, China.

Abundant behavioral studies have demonstrated high comorbidity of reading and handwriting difficulties in developmental dyslexia (DD), a neurological condition characterized by unexpectedly low reading ability despite adequate nonverbal intelligence and typical schooling. The neural correlates of handwriting deficits remain largely unknown, however, as well as the extent that handwriting deficits share common neural bases with reading deficits in DD. The present work used functional magnetic resonance imaging (fMRI) to examine brain activity during handwriting and reading tasks in Chinese dyslexic children (n = 18) and age-matched controls (n = 23). Read More

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The Effects of Exergaming on Sensory Reweighting and Mediolateral Stability of Women Aged Over 60: Usability Study.

JMIR Serious Games 2021 Jul 21;9(3):e27884. Epub 2021 Jul 21.

Doctoral School of Clinical Medicine, University of Szeged, Szeged, Hungary.

Background: Older adults tend to experience difficulties in switching quickly between various reliable sensory inputs, which ultimately may contribute to an increased risk of falls and injuries. Sideward falls are the most frequent cause of hip fractures among older adults. Recently, exergame programs have been confirmed as beneficial tools for enhancing postural control, which can reduce the risk of falls. Read More

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Utilising the Orthoptic Skill Set to Improve Access to Eye Care for Adults with Severe/Profound Learning Disabilities-A Service Evaluation.

Br Ir Orthopt J 2021 10;17(1):41-50. Epub 2021 Mar 10.

University of Liverpool, GB.

Intro: There is a wealth of research evidencing the high incidence of visual impairment (VI) and poor uptake of eye care services by adults with learning disabilities (LD). Despite this, very few authorities within England currently provide the additional support required by those with severe/profound LD (S/PLD).

Method: By means of an initial funded pilot study, an unmet need was evidenced locally and a small service established to improve access to eye care for adults with S/PLD. Read More

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An adaptive learning method of anchor shape priors for biological cells detection and segmentation.

Comput Methods Programs Biomed 2021 Jul 8;208:106260. Epub 2021 Jul 8.

College of Computer Science and Technology, Zhejiang University of Technology, Hangzhou 310023, PR China; Key Laboratory of Visual Media Intelligent Processing Technology of Zhejiang Province, Hangzhou 310023, PR China. Electronic address:

Background And Objective: Owing to the variable shapes, large size difference, uneven grayscale and dense distribution among biological cells in an image, it is still a challenging task for the standard Mask R-CNN to accurately detect and segment cells. Especially, the state-of-the-art anchor-based methods fail to generate the anchors of sufficient scales effectively according to the various sizes and shapes of cells, thereby hardly covering all scales of cells.

Methods: We propose an adaptive approach to learn the anchor shape priors from data samples, and the aspect ratios and the number of anchor boxes can be dynamically adjusted by using ISODATA clustering algorithm instead of human prior knowledge in this work. Read More

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Retreat for Advancing: Dynamic Reinforced Instruction Attacker for Robust Visual Navigation.

IEEE Trans Pattern Anal Mach Intell 2021 Jul 16;PP. Epub 2021 Jul 16.

Language instruction plays an essential role in the natural language grounded navigation tasks. However, navigators trained with limited human-annotated instructions may have difficulties in accurately capturing key information from the complicated instruction at different timesteps, leading to poor navigation performance. In this paper, we exploit to train a more robust navigator which is capable of dynamically extracting crucial factors from the long instruction, by using an adversarial attacking paradigm. Read More

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Emotion Understanding Correlates With Parental Emotional Expressivity in Chinese Youths With Hearing Loss and Typical Hearing.

Front Psychol 2021 29;12:662356. Epub 2021 Jun 29.

Luoding Middle School, Luo Ding, China.

This study aimed at examining the differences between Chinese youths with hearing loss (HL) and with typical hearing (TH) in emotion understanding (EU), parental emotional expressivity, and the associations between EU and parental emotional expressivity. The participants were 282 youths with HL (14.58 ± 3. Read More

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Alexithymia Is Associated With Deficits in Visual Search for Emotional Faces in Clinical Depression.

Front Psychiatry 2021 29;12:668019. Epub 2021 Jun 29.

Department of Psychosomatic Medicine and Psychotherapy, University of Leipzig Medical Center, Leipzig, Germany.

The concept of alexithymia is characterized by difficulties identifying and describing one's emotions. Alexithymic individuals are impaired in the recognition of others' emotional facial expressions. Alexithymia is quite common in patients suffering from major depressive disorder. Read More

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Social cognition in individuals born preterm.

Sci Rep 2021 07 14;11(1):14448. Epub 2021 Jul 14.

Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy.

Faces hold a substantial value for effective social interactions and sharing. Covering faces with masks, due to COVID-19 regulations, may lead to difficulties in using social signals, in particular, in individuals with neurodevelopmental conditions. Daily-life social participation of individuals who were born preterm is of immense importance for their quality of life. Read More

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Outcomes of periarterial sympathectomy in patients with digital ischemia.

Vascular 2021 Jul 14:17085381211032854. Epub 2021 Jul 14.

Department of Vascular and Endovascular Surgery, Faculty of Medicine, 68780Mansoura University, Mansoura, Egypt.

Introduction: Digital ischemia with subsequent severe pain and tissue loss is often difficult to treat, with no obvious guidelines or strong evidence in the literature to support a specific treatment modality. Patients who fail medical treatment remain with very limited surgical options due to the difficulty of any intervention in this "no man's land" area of the hand, as described since 1918. Extended distal periarterial sympathectomy is reported as an effective treatment option since the eighties of last century. Read More

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Georgian Med News 2021 May(314):129-134

Vinnytsia National Medical University, Ukraine.

The purpose of the study is to explore the peculiarities of cognitive functioning in the depressive phase of BAS, taking into account the gender factor. The results of the study are based on data from a clinical and psychological examination of 27 men and 39 women with bipolar disorder (BAD) and undergoing treatment at the Yushchenko Vinnytsia Regional Psychoneurological Hospital from 2016 to 2020 in connection with the current episode of mild or moderate depression (ICD-10 code F31.3). Read More

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Impact of the COVID-19 pandemic upon patients with burning mouth syndrome.

J Stomatol Oral Maxillofac Surg 2021 Jul 8. Epub 2021 Jul 8.

Interdisciplinary Laboratory of Clinical Analysis, Interlab-UMU, Regional Campus of International Excellence 'Campus Mare Nostrum', University of Murcia, Espinardo, 30100 Murcia, Spain. Electronic address:

Introduction: The global COVID-19 pandemic has caused changes in the daily life of people, with a particularly relevant impact upon certain groups of individuals that have difficulties in facing stress. A study is made of the impact of the pandemic upon patients with burning mouth syndrome (BMS).

Material And Methods: A total of 40 patients with BMS diagnosed in the Unit of Oral Medicine (University of Murcia, Spain) were included. Read More

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A Randomized Trial on Clinical Outcomes and Stent Related Symptoms Following Intraureteral Stent on a String versus Conventional Stent Placement.

BJU Int 2021 Jul 10. Epub 2021 Jul 10.

Dept of Urology and Renal Transplant, Kasturba Medical College, Manipal, Karnataka, India.

Introduction And Objective: To minimize stent-related symptoms (SRS), a modified complete intra-ureteral stent with extraction suture was designed. The objective was to compare SRS of the conventional DJ stent and the complete intraureteral stent using the validated Ureteral Stent Symptom Questionnaire (USSQ).

Materials And Methods: We randomized 124 patients after uncomplicated ureteroscopic lithotripsy into complete intraureteral stent (CIUS) and conventional DJ stent (CUS) placement group. Read More

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Visual prediction cues can facilitate behavioural and neural speech processing in young and older adults.

Neuropsychologia 2021 Aug 3;159:107949. Epub 2021 Jul 3.

France Aix Marseille Univ, CNRS, LPL, Aix-en-Provence, France.

The ability to process speech evolves over the course of the lifespan. Understanding speech at low acoustic intensity and in the presence of background noise becomes harder, and the ability for older adults to benefit from audiovisual speech also appears to decline. These difficulties can have important consequences on quality of life. Read More

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A Review of Driving and Binocularity.

J Pediatr Ophthalmol Strabismus 2021 Jun 1:1-7. Epub 2021 Jun 1.

Although most jurisdictions allow stereoscopically deficient and monocular individuals to drive, studies regarding these visual components' effects on driving have to date yielded contradicting results. Interviews, record reviews, and experiments have been used to unmask these effects. In interviews, participants with amblyopia reported several difficulties operating automobiles. Read More

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