475 results match your criteria differential modal

Diagnostic Validity of the Smart Aging Serious Game: An Innovative Tool for Digital Phenotyping of Mild Neurocognitive Disorder.

J Alzheimers Dis 2021 Aug 27. Epub 2021 Aug 27.

IRCCS Fondazione Don Carlo Gnocchi ONLUS, Milan-Florence, Italy.

Background: The Smart Aging Serious Game (SASG) is an ecologically-based digital platform used in mild neurocognitive disorders. Considering the higher risk of developing dementia for mild cognitive impairment (MCI) and vascular cognitive impairment (VCI), their digital phenotyping is crucial. A new understanding of MCI and VCI aided by digital phenotyping with SASG will challenge current differential diagnosis and open the perspective of tailoring more personalized interventions. Read More

View Article and Full-Text PDF

Comparisons of Differential Filtering and Homography Transformation in Modal Parameter Identification from UAV Measurement.

Sensors (Basel) 2021 Aug 23;21(16). Epub 2021 Aug 23.

School of Civil and Transportation Engineering, Guangdong University of Technology, Guangzhou 510006, China.

This paper proposes a differential filtering method for the identification of modal parameters of bridges from unmanned aerial vehicle (UAV) measurement. The determination of the modal parameters of bridges is a key issue in bridge damage detection. Accelerometers and fixed cameras have disadvantages of deployment difficulty. Read More

View Article and Full-Text PDF

Cross-modal auditory priors drive the perception of bistable visual stimuli with reliable differences between individuals.

Sci Rep 2021 Aug 20;11(1):16943. Epub 2021 Aug 20.

Department of Cognitive Science, Budapest University of Technology and Economics, 1 Egry József utca, Building T, Floor 5, Budapest, 1111, Hungary.

It is a widely held assumption that the brain performs perceptual inference by combining sensory information with prior expectations, weighted by their uncertainty. A distinction can be made between higher- and lower-level priors, which can be manipulated with associative learning and sensory priming, respectively. Here, we simultaneously investigate priming and the differential effect of auditory vs. Read More

View Article and Full-Text PDF

Physical therapy treatment of a pediatric patient with symptoms consistent with a spinal cord injury without radiographic abnormality: A retrospective case report.

J Bodyw Mov Ther 2021 Jul 11;27:455-463. Epub 2021 Feb 11.

American Academy of Manipulative Therapy, Montgomery, AL, USA; Montgomery Osteopractic Physiotherapy and Acupuncture Clinic, Montgomery, AL, USA.

Background: A spinal cord injury without radiographic abnormality (SCIWORA) is a relatively uncommon event that occurs in children following cervical trauma primarily due to sports-related injuries or physical abuse.

Case Description: This case report describes an 11-year-old wrestler that developed signs and symptoms consistent with a SCIWORA following neck trauma during competition. Despite all diagnostic tests being inconclusive, the patient demonstrated increased cervical, thoracic, and lumbar paraspinal tone along with pain, loss of sensation, loss of mobility, and weakness of the lower extremities. Read More

View Article and Full-Text PDF

Leakage channels enabled multi-resonant all-solid photonic bandgap fiber for effective single-mode propagation.

Opt Express 2021 Jul;29(14):22455-22469

All-solid photonic bandgap fiber (AS-PBGF) has been fully demonstrated to be a promising candidate of large-mode-area fiber for its mode-dependent selectivity and spectral filtering mechanism. In the present work, the concepts of multiple-resonant coupling and leakage channels are taken into consideration simultaneously for mode area scaling of AS-PBGF. The single-mode performance and bending resistance of a modified structure, called leakage channels enabled multi-resonant AS-PBGF (LC-PBGF), are evaluated numerically. Read More

View Article and Full-Text PDF

Structural analysis and optimization design of mechanical pendulum of differential capacitance seismometer.

Rev Sci Instrum 2021 Jun;92(6):064506

Institute of Geophysics, China Earthquake Administration, Beijing 100081, China.

Seismometers can collect and record earthquake information in real time, and they play an important role in earthquake prediction and post-earthquake monitoring. Aiming at the high natural frequency problem of the mechanical pendulum of differential capacitance seismometers, this study employed the ANSYS simulation software to establish a finite element model of the mechanical pendulum; using the constructed model, this study performed static and modal analysis on the key structure, the cross reed, and conducted topological optimization on the shape of the reed. Moreover, the sine calibration method was adopted to measure the natural frequency of the mechanical pendulum before and after optimization, and the experimental results showed that after optimization, the natural frequency of the mechanical pendulum had been reduced by 22%, decreasing from 5. Read More

View Article and Full-Text PDF

High-speed feedback control of an oscillating magnetic helicity injector using a graphics processing unit.

Rev Sci Instrum 2021 May;92(5):053530

CTFusion, Inc., Seattle, Washington 98121, USA.

A real-time control system has been developed to control the amplitude, phase, and offset of bulk plasma parameters inside an oscillating magnetic helicity injector. Control software running entirely on an Nvidia Tesla P40 graphical processing unit is able to receive digitizer inputs and send response patterns to a Pulse Width Modulation (PWM) controller with a minimum control loop period of 12.8 µs. Read More

View Article and Full-Text PDF

Exploring MEG brain fingerprints: Evaluation, pitfalls, and interpretations.

Neuroimage 2021 10 5;240:118331. Epub 2021 Jul 5.

Institute of Bioengineering, Center for Neuroprosthetics, École Polytechnique Fédérale De Lausanne (EPFL), Geneva, Switzerland; Department of Radiology and Medical Informatics, University of Geneva (UNIGE), Geneva, Switzerland. Electronic address:

Individual characterization of subjects based on their functional connectome (FC), termed "FC fingerprinting", has become a highly sought-after goal in contemporary neuroscience research. Recent functional magnetic resonance imaging (fMRI) studies have demonstrated unique characterization and accurate identification of individuals as an accomplished task. However, FC fingerprinting in magnetoencephalography (MEG) data is still widely unexplored. Read More

View Article and Full-Text PDF
October 2021

Functional Hyperconnectivity and Task-Based Activity Changes Associated With Neuropathic Pain After Spinal Cord Injury: A Pilot Study.

Front Neurol 2021 10;12:613630. Epub 2021 Jun 10.

Biomedical Engineering, University of Utah, Salt Lake City, UT, United States.

Neuropathic pain (NP) is a devastating chronic pain condition affecting roughly 80% of the spinal cord injury (SCI) patient population. Current treatment options are largely ineffective and neurophysiological mechanisms of NP are not well-understood. Recent studies in neuroimaging have suggested that NP patients have differential patterns of functional activity that are dependent upon the neurological condition causing NP. Read More

View Article and Full-Text PDF

Matched coordinates for the analysis of 1D gratings.

J Opt Soc Am A Opt Image Sci Vis 2021 Jun;38(6):790-798

The Fourier modal method (FMM) is certainly one of the most popular and general methods for the modeling of diffraction gratings. However, for non-lamellar gratings it is associated with a staircase approximation of the profile, leading to poor convergence rate for metallic gratings in TM polarization. One way to overcome this weakness of the FMM is the use of the fast Fourier factorization (FFF) first derived for the differential method. Read More

View Article and Full-Text PDF

Simple and precise characterization of differential modal group delay arising in few-mode fiber.

Opt Lett 2021 Jun;46(12):2856-2859

In this Letter, we propose a simple and high-precision differential modal group delay (DMGD) characterization method for few-mode fibers (FMF) by using the frequency-modulated continuous wave. Since the detected signals are located at the low-frequency range, our DMGD characterization method waives the use of expensive equipment, such as vector network or optical spectrum analyzers. Due to the high linearity of the used Mach-Zehnder modulator, our DMGD measurement is free from the complex auxiliary interferometer, leading to an improvement of characterization precision. Read More

View Article and Full-Text PDF

Clinical correlates of white matter lesions in Parkinson's disease using automated multi-modal segmentation measures.

J Neurol Sci 2021 08 1;427:117518. Epub 2021 Jun 1.

Singapore General Hospital, Singapore; Duke-NUS Medical School, Singapore. Electronic address:

Background: Age-related white matter lesions (WML) are common, impact neuronal connectivity, and affect motor function and cognition. In addition to pathological nigrostriatal losses, WML are also common co-morbidities in Parkinson's disease (PD) that affect postural stability and gait. Automated brain volume measures are increasingly incorporated into the clinical reporting workflow to facilitate precision in medicine. Read More

View Article and Full-Text PDF

Mode switching using optically induced long-period gratings: a theoretical analysis.

Opt Express 2021 May;29(10):14601-14614

We show that optically induced long-period grating (OLPG) is a particular case of inter-modal Bragg-scattering four-wave mixing (BS-FWM). To carry out such analysis, a vector model for the inter-modal BS-FWM was proposed and further tailored to investigate the energy transfer induced by OLPGs. Both processes, BS-FWM and OLPGs, have been proposed for in-line all-optical mode switching in transmission systems with space-division multiplexing (SDM). Read More

View Article and Full-Text PDF

How embryology knowledge can help radiologists in the differential diagnosis of canal of Nuck pathologies.

Radiol Med 2021 Jul 5;126(7):910-924. Epub 2021 May 5.

Diagnostic Imaging Department, San Paolo Hospital-ASL 2, via Genova, 30, Savona, Italy.

The Canal of Nuck (CN) is an anatomical structure which is often forgotten. It is the female equivalent of the male processus vaginalis and corresponds to a protrusion of parietal peritoneum that extends from the inguinal canal to labia majora. Radiologists rarely encounter patients with pathology of CN, especially in adult population. Read More

View Article and Full-Text PDF

The Hard X-ray Nanoprobe beamline at Diamond Light Source.

J Synchrotron Radiat 2021 May 9;28(Pt 3):1006-1013. Epub 2021 Apr 9.

Diamond Light Source, Harwell Science and Innovation Campus, Didcot, Oxfordshire OX11 0DE, United Kingdom.

The Hard X-ray Nanoprobe beamline, I14, at Diamond Light Source is a new facility for nanoscale microscopy. The beamline was designed with an emphasis on multi-modal analysis, providing elemental mapping, speciation mapping by XANES, structural phase mapping using nano-XRD and imaging through differential phase contrast and ptychography. The 185 m-long beamline operates over a 5 keV to 23 keV energy range providing a ≤50 nm beam size for routine user experiments and a flexible scanning system allowing fast acquisition. Read More

View Article and Full-Text PDF

Hemodynamic response to sensory stimulation in mice: Comparison between functional ultrasound and optoacoustic imaging.

Neuroimage 2021 08 30;237:118111. Epub 2021 Apr 30.

Institute for Biomedical Engineering and Institute of Pharmacology and Toxicology, Faculty of Medicine, University of Zurich, Wolfgang-Pauli-Str. 27, Zurich, CH 8093, Switzerland; Institute for Biomedical Engineering, Department of Information Technology and Electrical Engineering, ETH Zurich, Switzerland. Electronic address:

Intense efforts are underway to develop functional imaging modalities for capturing brain activity at the whole organ scale with high spatial and temporal resolution. Functional optoacoustic (fOA) imaging is emerging as a new tool to monitor multiple hemodynamic parameters across the mouse brain, but its sound validation against other neuroimaging modalities is often lacking. Here we investigate mouse brain responses to peripheral sensory stimulation using both fOA and functional ultrasound (fUS) imaging. Read More

View Article and Full-Text PDF

Explaining face-voice matching decisions: The contribution of mouth movements, stimulus effects and response biases.

Atten Percept Psychophys 2021 Jul 1;83(5):2205-2216. Epub 2021 Apr 1.

Department of Speech, Hearing and Phonetic Sciences, University College London, 2 Wakefield Street, London, WC1N 1PF, UK.

Previous studies have shown that face-voice matching accuracy is more consistently above chance for dynamic (i.e. speaking) faces than for static faces. Read More

View Article and Full-Text PDF

Activities of the Right Temporo-Parieto-Occipital Junction Reflect Spatial Hearing Ability in Cochlear Implant Users.

Front Neurosci 2021 12;15:613101. Epub 2021 Mar 12.

MEG Center, University of Tübingen, Tübingen, Germany.

Spatial hearing is critical for us not only to orient ourselves in space, but also to follow a conversation with multiple speakers involved in a complex sound environment. The hearing ability of people who suffered from severe sensorineural hearing loss can be restored by cochlear implants (CIs), however, with a large outcome variability. Yet, the causes of the CI performance variability remain incompletely understood. Read More

View Article and Full-Text PDF

scGNN is a novel graph neural network framework for single-cell RNA-Seq analyses.

Nat Commun 2021 03 25;12(1):1882. Epub 2021 Mar 25.

Department of Electrical Engineering and Computer Science, and Christopher S. Bond Life Sciences Center, University of Missouri, Columbia, MO, USA.

Single-cell RNA-sequencing (scRNA-Seq) is widely used to reveal the heterogeneity and dynamics of tissues, organisms, and complex diseases, but its analyses still suffer from multiple grand challenges, including the sequencing sparsity and complex differential patterns in gene expression. We introduce the scGNN (single-cell graph neural network) to provide a hypothesis-free deep learning framework for scRNA-Seq analyses. This framework formulates and aggregates cell-cell relationships with graph neural networks and models heterogeneous gene expression patterns using a left-truncated mixture Gaussian model. Read More

View Article and Full-Text PDF

A spectral characteristic analysis method for distinguishing heavy metal pollution in crops: VMD-PCA-SVM.

Spectrochim Acta A Mol Biomol Spectrosc 2021 Jul 9;255:119649. Epub 2021 Mar 9.

College of Geoscience and Surveying Engineering, China University of Mining and Technology-Beijing, Beijing 100083, China.

Exploring the characteristics and types of heavy metal pollution in crops has important implications for food security and human health. In this study, a method for distinguishing heavy metal-polluted elements in corn leaves was proposed. Based on the spectral data obtained from corn leaves polluted by Cu and Pb, the spectra were divided into four characteristic regions. Read More

View Article and Full-Text PDF

Sub-micron picoplankton shape, orientation, and internal structure combined to preferentially amplify the forward scatter.

Opt Express 2021 Jan;29(2):2014-2024

Compelling evidence is presented that sub-micron picoplankton shape, internal structure and orientation in combination leads to a disproportionate enhancement of differential forward scatter compared with differential side scatter when analyzed with a flow cytometer. Theoretical evidence is provided which results in an order of magnitude amplification in the forward scatter direction, with little or no change in the side scatter: this discounts the possibility of "doublets" caused by multiple particles simultaneously present in the laser beam. Observational evidence from progressively finer filtered seawater samples shows up to three orders of magnitude enhancement in the forward scatter direction and sizes of Prochlorococcus close to that reported in the literature (0. Read More

View Article and Full-Text PDF
January 2021

Arachnoiditis, a complication of epidural blood patch for the treatment of low-pressure headache: A case report and systematic review.

Headache 2021 02 13;61(2):244-252. Epub 2021 Feb 13.

Department of Neurology, University of Utah School of Medicine, Salt Lake City, UT, USA.

Objective: To report a case of arachnoiditis as a complication of epidural blood patch procedures and to systematically review the diagnostic workup, clinical outcomes, and treatment modalities reported in the literature.

Background: Epidural blood patching is an effective treatment for low-pressure headache secondary to spontaneous cerebrospinal fluid leak or iatrogenic post-dural puncture. Spontaneous intracranial hypotension is believed to be a rare headache disorder, but recently has been diagnosed at higher frequencies, making it an important differential diagnosis for intractable headaches. Read More

View Article and Full-Text PDF
February 2021

Model order reduction of thermo-mechanical models with parametric convective boundary conditions: focus on machine tools.

Comput Mech 2021 24;67(1):167-184. Epub 2020 Sep 24.

Institute of Machine Tool and Manufacturing, ETH Zurich, Leonhardstrasse 21, 8092 Zurich, Switzerland.

Thermo-mechanical finite element (FE) models predict the thermal behavior of machine tools and the associated mechanical deviations. However, one disadvantage is their high computational expense, linked to the evaluation of the large systems of differential equations. Therefore, projection-based model order reduction (MOR) methods are required in order to create efficient surrogate models. Read More

View Article and Full-Text PDF
September 2020

Atypical presentation of peripheral posterior lenticonus and role of multi-modal ocular imaging in its diagnosis and management.

BMJ Case Rep 2021 Feb 5;14(2). Epub 2021 Feb 5.

Ophthalmology, All India Institute of Medical Sciences, New Delhi, India

A 6-year-old systemically healthy child presented with visual acuity of 1/60, N18 oculusdextrus (OD), and 6/18, N6 oculus sinister (OS). Slit-lamp biomicroscopy revealed suspicious bilateral inferotemporal pigmented ciliary body (CB) tumour, protruding posterior capsule and temporal posterior subcapsular cataract oculus uterque. Anterior segment optical coherence tomography, ultrasonography, ultrasonic biomicroscopy and Scheimpflug imaging revealed protruding posterior capsule and cortex abutting but not arising from CB suggestive of peripheral pigmented posterior lenticonus with hypermetropia (axial length 20. Read More

View Article and Full-Text PDF
February 2021

Differential Cortical Pattern in Auditory Task Oddball Paradigm in Children Exposed to Alcohol during Pregnancy.

Neuroscience 2021 03 27;458:54-63. Epub 2021 Jan 27.

Department of Neuroscience and Behavioral Sciences, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, SP, Brazil.

The negative effects of fetal alcohol exposure on child development are well documented. This study investigated the electrophysiological processing of cortical level acoustic signals in a group of 21 children prenatally exposed to alcohol. Participants aged 13-14 years at the time of the study were recruited from a longitudinal cohort sample. Read More

View Article and Full-Text PDF

Gray matter volume in the right angular gyrus is associated with differential patterns of multisensory integration with aging.

Neurobiol Aging 2021 04 25;100:83-90. Epub 2020 Dec 25.

School of Psychology and Institute of Neuroscience, Trinity College Dublin, Dublin, Ireland.

Multisensory perception might provide an important marker of brain function in aging. However, the cortical structures supporting multisensory perception in aging are poorly understood. In this study, we compared regional gray matter volume in a group of middle-aged (n = 101; 49-64 years) and older (n = 116; 71-87 years) adults from The Irish Longitudinal Study on Aging using voxel-based morphometry. Read More

View Article and Full-Text PDF

A Multi-Modal Remote Clinical Skills Mini-Course Utilizing a Teaching TeleOSCE.

Med Sci Educ 2021 Jan 7:1-7. Epub 2021 Jan 7.

Department of Pediatrics, Rutgers New Jersey Medical School, Newark, NJ USA.

In the setting of the coronavirus pandemic, medical schools across the world transitioned to a remote learning curriculum with the challenge of developing innovative methods to teach clinical skills. During the pandemic, we designed a 2-week remote clinical skills mini-course for third year medical students. The focus was on clinical reasoning, counseling, and the following the Association of American Medical Colleges (AAMC) Core Entrustable Professional Activities (EPAs): 1 (history and physical exam), 2 (prioritize a differential diagnosis), 3 (recommend and interpret diagnostic tests), and 5 (document a clinical encounter). Read More

View Article and Full-Text PDF
January 2021

Generalized Reflexive Responding and Cross-Modal Tactile Transfer of Stimulus Function in Children with Autism.

Anal Verbal Behav 2020 Dec 17;36(2):233-250. Epub 2020 Nov 17.

Psychology Department, Southern Illinois University, Carbondale, IL USA.

We sought to evaluate the efficacy of successive matching training for establishing generalized reflexive matching across 4 children with autism. In Experiment 1, differential reinforcement with delay fading was efficacious in establishing "yes" and "no" matching and nonmatching responses in 2 participants when 2 identical or nonidentical picture stimuli were presented. In addition, emergent visual-visual reflexive relational responses were observed using novel picture stimuli in a transfer test phase. Read More

View Article and Full-Text PDF
December 2020

[Features of the neuroradiological picture of ganglioglioma on the example of 20 clinical cases].

Zh Nevrol Psikhiatr Im S S Korsakova 2020 ;120(11):90-98

Pirogov Russian National Research Medical University, Moscow, Russia.

Objective: To analyze the images obtained during pre-surgical neuroimaging in patients with gangliomas for the presence of specific signs and verification of the neoplastic process.

Material And Methods: The results of presurgical MRI (3.0, 1. Read More

View Article and Full-Text PDF
December 2020

Deep Learning Methodology for Differentiating Glioma Recurrence From Radiation Necrosis Using Multimodal Magnetic Resonance Imaging: Algorithm Development and Validation.

JMIR Med Inform 2020 Nov 17;8(11):e19805. Epub 2020 Nov 17.

Centre for Health Informatics, Australian Institute of Health Innovation, Macquarie University, Sydney, Australia.

Background: The radiological differential diagnosis between tumor recurrence and radiation-induced necrosis (ie, pseudoprogression) is of paramount importance in the management of glioma patients.

Objective: This research aims to develop a deep learning methodology for automated differentiation of tumor recurrence from radiation necrosis based on routine magnetic resonance imaging (MRI) scans.

Methods: In this retrospective study, 146 patients who underwent radiation therapy after glioma resection and presented with suspected recurrent lesions at the follow-up MRI examination were selected for analysis. Read More

View Article and Full-Text PDF
November 2020