229,187 results match your criteria difference observed


A comparison of meta-analysis results with and without adjustment for healthy worker effect: cancer mortality among workers in the semiconductor industry.

Epidemiol Health 2021 Sep 8:e2021057. Epub 2021 Sep 8.

Department of Environmental Health, Korea National Open University, Seoul, Korea.

Objectives: To compare meta-analysis results with and without adjustment for healthy worker effect on the association between working in the semiconductor industry and cancer mortality.

Methods: A total of six studies that reported standardized mortality ratios (SMRs) for cancers were selected for meta-analysis. The SMR results from individual study were combined for all cancers, leukemia and lymphoma to estimate the summary SMRs and 95% confidence intervals (CIs) with random-effects model. Read More

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September 2021

Comparing Different Techniques in Children With or Without a Simultaneous Fundoplication: Does the Gastrostomy Technique Matter?

J Laparoendosc Adv Surg Tech A 2021 Sep 12;31(9):1067-1072. Epub 2021 Jul 12.

Department of Pediatric Gastroenterology, Hepatology and Nutrition, Ondokuz Mayıs University Medical School, Samsun, Turkey.

To evaluate the results of different gastrostomy techniques and the impact of simultaneous fundoplication. The patients who underwent a gastrostomy procedure between 2009 and 2019 in a single tertiary center were evaluated retrospectively. The patients are divided into groups depending on the gastrostomy techniques as open gastrostomy (OG), laparoscopic gastrostomy (LG), percutaneous endoscopic gastrostomy (PEG), and laparoscopy-assisted PEG (LAPEG). Read More

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September 2021

Hydrokinetic pancreatic function and insulin secretion are moduled by Cl uniporter Slc26a9 in mice.

Acta Physiol (Oxf) 2021 Sep 15:e13729. Epub 2021 Sep 15.

Dept. of Gastroenterology, Hannover Medical School, Hannover, Germany.

Aim: Slc26a9 is a member of the Slc26 multifunctional anion transporter family. Polymorphisms in Slc26a9 are associated with an increased incidence of meconium ileus and diabetes in cystic fibrosis patients. We investigated the expression of Slc26a9 in the murine pancreatic ducts, islets and parenchyma, and elucidated its role in pancreatic ductal electrolyte and fluid secretion and endocrine function. Read More

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September 2021

Phenotypic and Genotypic Characterization of Salmonella spp. Isolated from Foods Involved in Human Salmonellosis Outbreaks in Minas Gerais State, Brazil.

J Food Prot 2021 Sep 15. Epub 2021 Sep 15.

Fundacao Ezequiel Dias Rua Conde Pereira Carneiro, 80 BRAZIL Belo Horizonte Minas Gerais 30510-010 +55 31 98883-5638.

Salmonella spp. is one of the primary pathogens that cause foodborne diseases worldwide. In the present study, we deeply characterized Salmonella spp. Read More

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September 2021

Circularly polarized optical microscope using a low aberration liquid crystal lens.

Opt Lett 2021 Sep;46(18):4434-4437

We demonstrate a circularly polarized optical microscope (POM) by incorporating a hole-patterned electrode (HPE) liquid crystal (LC) lens fabricated by photoalignment. The focal plane is controlled by voltages on the HPE LC lens with a tuning range of 2.2 mm without any mechanical movement. Read More

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September 2021

Hyperparathyroidism in patients with overt and mild primary aldosteronism.

Hormones (Athens) 2021 Sep 15. Epub 2021 Sep 15.

Unit of Endocrinology and Diabetes Centre, General Hospital of Athens "G Gennimatas", 154 Mesogeion Avenue, 11527, Athens, Greece.

Introduction: Increased prevalence of hyperparathyroidism (HP) has been observed in primary aldosteronism (PA) patients. However, HP prevalence in milder forms of PA has not to date been evaluated.

Objectives: The objectives of this study were to assess the prevalence of primary and secondary HP in overt and milder misdiagnosed cases of PA and to investigate the effect of treatment on parathormone (PTH) secretion. Read More

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September 2021

Morphological, Biochemical, and Proteomic Studies Revealed Impact of Fe and P Crosstalk on Root Development in Phaseolus vulgaris L.

Appl Biochem Biotechnol 2021 Sep 15. Epub 2021 Sep 15.

Division of Agricultural Statistics, Sher-E-Kashmir University of Agricultural Sciences & Technology of Kashmir, Shalimar, Srinagar, Jammu & Kashmir, India.

Mineral stress is one of the major abiotic stresses faced by crop plants. The present study was undertaken to investigate the impact of mineral stress (iron (Fe) and phosphorus (P)) on various morphological and biochemical responses of the shoot and root tissues and root architecture of common bean (Phaseolus vulgaris L.). Read More

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September 2021

Management and Survival Analysis of Gastrointestinal Neuroendocrine Tumors by Different Tumor Characteristics: Tertiary Center Experience.

J Gastrointest Cancer 2021 Sep 15. Epub 2021 Sep 15.

Department of Pathology, Faculty of Medicine, Inonu University, Malatya, 44280, Turkey.

Background: Gastrointestinal neuroendocrine tumor (GI-NET) is a group of neoplasia consisting of amine and acid producing cells with different hormonal profiles. Although the entire GIS accounts for about 2% of tumors, recent research reveals that the incidence rate has increased. Given the increasing incidence in GI-NETs, more and more extensive research is needed on this subject. Read More

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September 2021

Global alignment taking into account the cervical spine with odontoid hip axis angle (OD-HA).

Eur Spine J 2021 Sep 15. Epub 2021 Sep 15.

Laboratoire de biomecanique Georges Charpak, Ecole nationale superieure des arts et metiers, 75013, Paris, France.

Introduction: Global alignment analysis is of upmost importance in adult spinal deformity patients (ASD). Numerous parameters exist in the literature to measure global alignment based upon C7 or T1. One common limitation of these parameters is that they neglect the cervical segment which is essential in spinal compensatory mechanisms and in horizontal gaze preservation. Read More

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September 2021

Normal anatomy, variants and factors associated with the cervical vagus nerve topography: a high-resolution ultrasound study.

Surg Radiol Anat 2021 Sep 15. Epub 2021 Sep 15.

Department of Anatomy, School of Medicine, University of Crete, Heraklion, Crete, Greece.

Purpose: To describe the cervical vagus nerve (CVN) topography at the thyroid lobe (TL) level using high-resolution ultrasound and to investigate the possible association with anthropometric data, TL size, and thyroid disease.

Methods: We prospectively examined 550 CVNs in 275 (205 female, 70 male) individuals with normal thyroid (53/275, 19.3%), multinodular disease (167/275, 60. Read More

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September 2021

Sirolimus (Rapamycin) for Slow-Flow Malformations in Children: The Observational-Phase Randomized Clinical PERFORMUS Trial.

JAMA Dermatol 2021 Sep 15. Epub 2021 Sep 15.

University of Tours, Centre Hospitalier Régional Universitaire Tours, Department of Pediatric Radiology, Tours, France.

Importance: Sirolimus is increasingly being used to treat various vascular anomalies, although evidence of its efficacy is lacking.

Objective: To assess the efficacy and safety of sirolimus for children with slow-flow vascular malformations to better delineate the indications for treatment.

Design, Setting And Participants: This multicenter, open-label, observational-phase randomized clinical trial included 59 children aged 6 to 18 years with a slow-flow vascular malformation who were recruited between September 28, 2015, and March 22, 2018, in 11 French tertiary hospital centers. Read More

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September 2021

Perturbations in Gut Microbiota Composition in Psychiatric Disorders: A Review and Meta-analysis.

JAMA Psychiatry 2021 Sep 15. Epub 2021 Sep 15.

Centre for Affective Disorders, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, United Kingdom.

Importance: Evidence of gut microbiota perturbations has accumulated for multiple psychiatric disorders, with microbiota signatures proposed as potential biomarkers. However, no attempts have been made to evaluate the specificity of these across the range of psychiatric conditions.

Objective: To conduct an umbrella and updated meta-analysis of gut microbiota alterations in general adult psychiatric populations and perform a within- and between-diagnostic comparison. Read More

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September 2021

Treatment of thoracolumbar fractures by temporary posterior instrumentation with selective fusion schemes.

Br J Neurosurg 2021 Sep 15:1-8. Epub 2021 Sep 15.

Department of Orthopedic Surgery, Spine Center, Second Affiliated Hospital of Naval Medical University, Shanghai, P. R. China.

Objective: This retrospective study investigated the clinical and radiographic outcomes following temporary transpedicular posterior instrumentation between two cohorts of patients with thoracolumbar fractures (TLF) who underwent selective or bi-segments intervertebral articular process fusion.

Methods: Patients with TLF who underwent the temporary posterior fixation with selective fusion (Group SF), or bi-segments fusion (Group BF) were studied. Superior intervertebral articular process and interlaminar fusion were performed in Group SF, whereas in Group BF, the patients underwent bi-segments fusion in both superior and inferior articular processes, as well as interlaminar fusion. Read More

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September 2021

CGM sensor glucose levels and insulin pump infusion set wear-time during treatment with fast-acting insulin aspart: a post hoc analysis of onset 5.

Diabetes Technol Ther 2021 Sep 15. Epub 2021 Sep 15.

Novo Nordisk AS, 1450, Medical & Science, Søborg, Denmark;

: In the onset 5 trial, fast-acting insulin aspart (faster aspart) was non-inferior to insulin aspart (IAsp) for change from baseline glycated hemoglobin at 16 weeks, when used in continuous subcutaneous insulin infusion by participants with type 1 diabetes. The aim of this post hoc analysis was to investigate whether infusion set wear-time was associated with changes in sensor glucose, measured using continuous glucose monitoring (CGM). : This was a post hoc analysis of onset 5 data. Read More

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September 2021

Impact of COVID-19 on Timing of Hip-Fracture Surgeries: An Interrupted Time-Series Analysis of the Pre/Post-Quarantine Period in Northern Italy.

Int J Health Policy Manag 2021 Sep 1. Epub 2021 Sep 1.

Department of Public Health Sciences and Paediatrics, Università di Torino, Torino, Italy.

Background: To assess whether the imposition of the coronavirus disease 2019 (COVID-19) national quarantine (March 10, 2020) resulted in a shift in the proportion of patients operated for hip fracture on the day of admission, the following day and two days after admission in the region of Piedmont, northern Italy.

Methods: Interrupted time-series analysis (ITSA) comparing hospitalization rate and timing of hip-fracture surgeries between pre- and post-quarantine period. The same data observed in Piedmont the year before were included as a control time series with no "intervention" (quarantine) in the middle of the observation period. Read More

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September 2021

Original Designed Uniportal-Bichannel Spinal Endoscopic System (UBiSES) for Foraminoplasty in Percutaneous Endoscopic Transforaminal Discectomy.

Orthop Surg 2021 Sep 15. Epub 2021 Sep 15.

Orthopaedics Department, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China.

Objective: The study introduced uniportal-bichannel spinal endoscopic system (UBiSES) and explored the feasibility of applying UBiSES to conduct lumbar foraminoplasty in percutaneous endoscopic transforaminal discectomy (PETD).

Methods: This is a cohort study. 36 patients confirmed as L5/S1 lumbar disc herniation (LDH) in our hospital from March, 2019 to November, 2019 were enrolled. Read More

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September 2021

[Comparison of unicompartmental knee arthroplasty and total knee arthroplasty in the treatment of severe medial compartment osteoarthritis].

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi 2021 Sep;35(9):1125-1132

Department of Orthopedics, West China Hospital, Sichuan University, Chengdu Sichuan, 610041, P.R.China.

Objective: To compare the effectiveness of unicompartmental knee arthroplasty (UKA) and total knee arthroplasty (TKA) in the treatment of severe medial compartment osteoarthritis (OA).

Methods: A clinical data of 69 patients (69 knees), who underwent joint replacement due to severe medial compartment OA between February 2015 and September 2018 and met the selection criteria, was retrospectively analyzed. Among them, 38 cases were treated with UKA (UKA group) and 31 cases with TKA (TKA group). Read More

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September 2021

[Morphological analysis of coronal femoral intertrochanteric fracture and its effect on reduction and internal fixation].

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi 2021 Sep;35(9):1093-1099

Department of Orthopedics, Luodian Hospital, Baoshan District, Shanghai, 201908, P.R.China.

Objective: To investigate the morphology of coronal femoral intertrochanteric fracture and its effect on reduction and internal fixation.

Methods: The clinical and imaging data of 46 patients with femoral intertrochanteric fracture who met the selection criteria between August 2017 and October 2018 were reviewed. There were 15 males and 31 females; the age ranged from 62 to 91 years, with an average of 72. Read More

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September 2021

Relation between number of teeth, malnutrition, and 3-year mortality in elderly individuals ≥ 85 years.

Oral Dis 2021 Sep 14. Epub 2021 Sep 14.

Department of Complete Denture Prosthodontics, Nihon University School of Dentistry, Tokyo, Japan.

Objective: The number of teeth has been shown to affect mortality. However, it is unclear why the number of teeth is associated with mortality. We focused on the number of teeth and malnutrition and examined whether these differences affect 3-year all-cause mortality among very elderly individuals. Read More

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September 2021

Depressive symptoms interfere with the improvement in exercise capacity by cardiac rehabilitation after left ventricular assist device implantation.

Artif Organs 2021 Sep 14. Epub 2021 Sep 14.

Faculty of Rehabilitation, Shijonawate Gakuen University, 5-11-10 Houjou Daito, Osaka, 574-0011, Japan.

Background: Although depressive symptoms are associated with an increased risk of readmission after left ventricular assist device (LVAD) implantation, it is unclear whether they affect the efficacy of exercise-based cardiac rehabilitation (EBCR). This study aimed to investigate the effect of depressive symptoms on EBCR efficacy.

Methods: We analyzed 48 patients who participated in EBCR after LVAD implantation (mean age 45±12 years; 60% male). Read More

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September 2021

Prenatal alcohol and cannabis exposure can have opposing and region-specific effects on parvalbumin interneuron numbers in the hippocampus.

Alcohol Clin Exp Res 2021 Sep 15. Epub 2021 Sep 15.

Division of Medical Sciences, University of Victoria, 3800 Finnerty Rd, Victoria, BC, V8P 5C2, Canada.

Background: We have recently shown that alcohol and cannabis can interact prenatally, and in a recent review paper we further identified Parvalbumin-positive (PV) interneurons in the hippocampus as a potential point of convergence for these teratogens.

Methods: A 2 (EtOH, Air) x 2 (THC, Vehicle) design was used to expose pregnant Sprague-Dawley rats to either EtOH or air, in addition to either THC or the inhalant vehicle solution, from gestational days 5-20. Immunohistochemistry was performed to detect parvalbumin-positive interneurons in one male and one female pup from each litter at post-natal day (PND) 70. Read More

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September 2021

Time course of symptoms in posttraumatic stress disorder with delayed expression: a systematic review.

Acta Psychiatr Scand 2021 Sep 15. Epub 2021 Sep 15.

Centre for Neuropsychiatric Depression Research, Mental Health Centre Glostrup and Clinical Institute, University of Copenhagen, Copenhagen, Denmark.

Objective: to examine the hypothesis that PTSD with delayed expression in some cases occur without subthreshold PTSD symptoms above background levels bridging the gap between the traumatic exposure(s) and the clinical diagnosis.

Methods: We performed systematic searches of peer-reviewed papers in English referenced in Pubmed, Embase or PsycINFO and ascertained 34 prospective studies of PTSD symptom trajectories identified by latent class growth statistical modeling. Studies with delayed and low-stable trajectories provided appropriate data for this study. Read More

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September 2021

Near-field prediction of chemical hazard diffusion based on improved differential evolution algorithm and fireworks algorithm.

Environ Monit Assess 2021 Sep 14;193(10):650. Epub 2021 Sep 14.

Digital China Research Institute (Fujian), Fuzhou University, Fuzhou, China.

In view of the advantages of CFD technology in the simulation of small and medium-scale chemical hazard diffusion, one near-field prediction model of chemical hazard diffusion named CHDNFP is constructed based on CFD technology, and the accuracy and efficiency of the model are improved by improved differential evolution algorithm (DEA) and fireworks algorithm (FWA). Firstly, based on the component conservation equation, momentum conservation equation, and turbulence control equation, CHDNFP model is constructed, whose basic solution process is proposed from three aspects: non-uniform mesh refinement in diffusion space, model discretization, and iterative solution of control equation. Secondly, comprehensive considering the global search ability, local search ability, and convergence characteristics of integrated DEA and FWA, a hybrid optimization algorithm IDEFWA is designed, which is suitable for predictive model solving. Read More

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September 2021

The impact of constant antibiotic prophylaxis in children affected by spinal dysraphism performing clean intermittent catheterization: a 2-year monocentric retrospective analysis.

Childs Nerv Syst 2021 Sep 14. Epub 2021 Sep 14.

Unità Operativa Spina Bifida e Uropatie Malformative, Dipartimento Di Scienze Della Salute Della Donna, Del bambino e Di sanità pubblica, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.

Introduction: Spinal dysraphism (SD) is a general term used to refer to developmental abnormalities of the spine that involves many clinical conditions including myelomeningocele (MMC). In these patients, neurogenic bladder (NB) is a common and predisposing factor for renal damage; the most frequently used approach to manage this situation is based on clean intermittent catheterization (CIC) and anticholinergic drugs. Urinary tract infections (UTIs) are a significant concern for these patients, and antibiotic prophylaxis is frequently used even if it is still a debated topic of literature. Read More

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September 2021

Molecular Monitoring of BCR-ABL Fusion Transcripts in Patients with Chronic Myeloid Leukemia During Treatment Using the Endpoint Fluorescence Method.

Lab Med 2021 Sep 15. Epub 2021 Sep 15.

Islamic International Medical College, Rawalpindi, Pakistan, and Riphah International University, Islamabad, Pakistan.

Objective: The purpose of the study was to compare results and evaluate the agreement between the endpoint fluorescence (EPF) method and quantitative real-time polymerase chain reaction (QPCR) during molecular monitoring of patients with chronic myeloid leukemia (CML) receiving treatment.

Materials And Methods: The study was conducted at Molecular Lab of Riphah International University, Islamabad, Pakistan, from January 2017 to December 2018. A total of 150 blood specimens from 30 patients with CML were analyzed at regular intervals during therapy. Read More

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September 2021

Concordance between PCR-based extraction-free saliva and nasopharyngeal swabs for SARS-CoV-2 testing.

HRB Open Res 2021 30;4:85. Epub 2021 Jul 30.

School of Pharmacy and Biomolecular Sciences, Royal College of Surgeons in Ireland, Dublin, Ireland.

: Saliva represents a less invasive alternative to nasopharyngeal swab (NPS) for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) detection. SalivaDirect is a nucleic acid extraction-free method for detecting SARS-CoV2 in saliva specimens. Studies evaluating the concordance of gold standard NPS and newly developed SalivaDirect protocols are limited. Read More

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Comparative response of some tropical maize hybrid and their parental varieties to low and high nitrogen regime.

Heliyon 2021 Sep 2;7(9):e07909. Epub 2021 Sep 2.

Crop and Soil Department Landmark University, Omuaran, Kwara State, Nigeria.

The study was carried to investigate the differential response of some maize hybrids and their open pollinated parents to low and high nitrogen soil condition. Ten open-pollinated varieties were crossed in a partial diallel fashion to generate 45 F hybrids during the 2011 cropping season at the International Institute of Tropical Agriculture (IITA), Ibadan, Nigeria. The 45 F hybrids and the ten parents were evaluated in four environments at Mokwa and Zaria in August, 2012 under high and low N conditions with two different levels of nitrogen application (30kgha and 90kgha) respectively. Read More

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September 2021

Genetic variability, heritability and correlation analysis among maturity and yield traits in Cowpea ( (L) Walp) in Northern Ghana.

Heliyon 2021 Sep 28;7(9):e07890. Epub 2021 Aug 28.

Council for Scientific and Industrial Research - Savanna Agricultural Research Institute, Ghana.

Experimental studies were conducted to evaluate 16 advanced breeding lines of cowpea ( (L) Walp) for genetic variability, heritability and correlation between maturity and yield related traits. The genotypes exhibited significant ( < 0.05) differences for the eight traits evaluated viz. Read More

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September 2021

Amygdalar endocannabinoids are affected by predator odor stress in a sex-specific manner and modulate acoustic startle reactivity in female rats.

Neurobiol Stress 2021 Nov 3;15:100387. Epub 2021 Sep 3.

Department of Physiology, School of Medicine, Louisiana State University Health Sciences Center, New Orleans, LA, USA.

Understanding sex differences in behavioral and molecular effects of stress has important implications for understanding the vulnerability to chronic psychiatric disorders associated with stress response circuitry. The amygdala is critical for emotional learning and generating behavioral responses to stressful stimuli, and preclinical studies indicate that amygdalar endocannabinoid (eCB) signaling regulates emotional states. This study measured eCB contents in the basolateral (BLA) and central (CeA) amygdala of male and female rats exposed to predator odor stress (bobcat urine) and tested for contextual avoidance 24 h later. Read More

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November 2021

Image-Guided Versus Blind Corticosteroid Injections in Adults With Shoulder Pain: A Systematic Review and Meta-Analysis.

Cureus 2021 Aug 9;13(8):e17032. Epub 2021 Aug 9.

Department of Surgery, Adesh Institute of Medical Sciences and Research, Bathinda, IND.

The present study aimed to compare the clinical effects of image-guided versus blind steroid injection to treat shoulder pain, which is always debatable. An electronic search of credible databases was conducted for randomized controlled trials (RCTs) comparing image-guided versus blind steroid injections. The continuous data were pooled as mean difference (MD) or standardized mean difference (SMD), and dichotomous data were grouped as odds ratio (OR) with 95% confidence interval (CI). Read More

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