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A comparison of meta-analysis results with and without adjustment for healthy worker effect: cancer mortality among workers in the semiconductor industry.

Epidemiol Health 2021 Sep 8:e2021057. Epub 2021 Sep 8.

Department of Environmental Health, Korea National Open University, Seoul, Korea.

Objectives: To compare meta-analysis results with and without adjustment for healthy worker effect on the association between working in the semiconductor industry and cancer mortality.

Methods: A total of six studies that reported standardized mortality ratios (SMRs) for cancers were selected for meta-analysis. The SMR results from individual study were combined for all cancers, leukemia and lymphoma to estimate the summary SMRs and 95% confidence intervals (CIs) with random-effects model. Read More

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September 2021

High-temperature oxidation and reduction of the inverse ceria/Cu(111) catalyst characterized by LEED, STM, nc-AFM and KPFM.

J Phys Condens Matter 2021 Sep 15. Epub 2021 Sep 15.

CNRS, CINaM UMR7325, Campus de Luminy, Case 913, Marseille Cedex 09, Provence, 13288, FRANCE.

The inverse catalyst 'cerium oxide (ceria) on copper' has attracted much interest in recent time because of its promising catalytic activity in the water-gas-shift reaction and the hydrogenation of CO. For such reactions it is important to study the redox behaviour of this system, in particular with respect to the reduction by H. Here, we investigate the high-temperature Ooxidation and Hreduction of ceria nanoparticles (NP) and a Cu(111) support by low energy electron diffraction (LEED), scanning tunnelling microscopy (STM), noncontact atomic force microscopy (nc-AFM) and Kelvin probe force microscopy (KPFM). Read More

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September 2021

Modelling electrocatalytic reactions with a concerted treatment of multistep electron transfer kinetics and local reaction conditions.

J Phys Condens Matter 2021 Sep 15. Epub 2021 Sep 15.

Ulm University, Institute of Theoretical Chemistry, Ulm University, 89069 Ulm Germany, Ulm, 89069, GERMANY.

A physicochemical model is developed for electrocatalytic reactions involving multiple electron transfer steps occurring in the electric double layer (EDL). The local reaction conditions are calculated using a mean-field EDL model, which is derived from a comprehensive grand potential that considers the steric effects, solvent polarization, and chemisorption-induced surface dipoles. Macroscopic mass transport in the so-called diffusion layer is controlled by the same set of controlling equations of the EDL model without imposing the electroneutrality assumption as usual. Read More

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September 2021

Biomechanical assessment of two types and two different locations of subtalar arthroereisis implants for flexible flatfoot: A cadaveric study.

Clin Biomech (Bristol, Avon) 2021 Aug 30;89:105475. Epub 2021 Aug 30.

Department of Orthopedics, Huashan Hospital, Fudan University, 12 Middle Wulumuqi Road, Shanghai 200040, China. Electronic address:

Background: Subtalar arthroereisis refers to the implantation of a sinus tarsi implant for the treatment of flexible flatfoot. The purpose of this study was to compare the ability to correct the flatfoot deformity and contact pressure of the posterior subtalar joint between two types of self-locking wedge implants and between two different positions for the same device in a cadaveric flatfoot model.

Methods: The flatfoot model was created in ten cadaver feet through ligament sectioning and cyclic loading. Read More

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Rapid Risk Stratification of Acute Ischemic Stroke Patients in the Emergency Department: The Incremental Prognostic Role of Left Atrial Reservoir Strain.

J Stroke Cerebrovasc Dis 2021 Sep 12;30(11):106100. Epub 2021 Sep 12.

Department of Cardiology, MultiMedica IRCCS, San Giuseppe Hospital, Milan, Italy.

Objectives: To determine the prognostic value of positive global left atrial strain (LA-GSA+), measured by two-dimensional speckle tracking echocardiography (2D-STE) in a population of acute ischemic stroke (AIS) patients without atrial fibrillation (AF), in the setting of Emergency Department (ED).

Methods: All consecutive AIS patients with sinus rhythm on ECG and without AF history entered this prospective study. All patients underwent complete blood tests and transthoracic echocardiography implemented with 2D-STE analysis of LA strain parameters within 6-12 h after symptoms onset. Read More

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September 2021

No association between children's febrile seizures and S100B protein levels: A meta-analysis.

Seizure 2021 Aug 31;92:158-165. Epub 2021 Aug 31.

The First Affiliated Hospital of Hebei Medical University, Shijiazhuang, Hebei, China. Electronic address:

Background: In recent years, studies have examined the relationship between febrile seizures in children and S100B protein with contradictory results. We systematically evaluated the relationship between children's febrile seizures and S100B protein levels.

Methods: We used Stata 11. Read More

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Comparing Different Techniques in Children With or Without a Simultaneous Fundoplication: Does the Gastrostomy Technique Matter?

J Laparoendosc Adv Surg Tech A 2021 Sep 12;31(9):1067-1072. Epub 2021 Jul 12.

Department of Pediatric Gastroenterology, Hepatology and Nutrition, Ondokuz Mayıs University Medical School, Samsun, Turkey.

To evaluate the results of different gastrostomy techniques and the impact of simultaneous fundoplication. The patients who underwent a gastrostomy procedure between 2009 and 2019 in a single tertiary center were evaluated retrospectively. The patients are divided into groups depending on the gastrostomy techniques as open gastrostomy (OG), laparoscopic gastrostomy (LG), percutaneous endoscopic gastrostomy (PEG), and laparoscopy-assisted PEG (LAPEG). Read More

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September 2021

A Comparison of Clinical Outcomes Between Two Different Models of Surgical Robots in Roux-en-Y Gastric Bypass.

J Laparoendosc Adv Surg Tech A 2021 Sep 17;31(9):969-977. Epub 2021 Aug 17.

General Surgery Department, Vall d'Hebron University Hospital, Universitat Autònoma de Barcelona, Barcelona, Spain.

For the past 20 years, robotic surgical systems have been used for the Roux-en-Y gastric bypass (RYGB). The da Vinci Surgical System (Intuitive Surgical, Inc.) has been one of the most used robotic platforms. Read More

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September 2021

Age-Related Functional Reserve Decline Is Not Seen in Pharyngeal Swallowing Pressures.

J Speech Lang Hear Res 2021 Sep 15:1-8. Epub 2021 Sep 15.

Department of Neurology, Dell Medical School, The University of Texas at Austin.

Purpose Functional reserve represents the difference between an individual's ability to produce a maximum output function and the ability to perform a functional task. Several studies have documented an age-related decrease in functional reserve with oral tongue pressure generation. Whether this pattern is seen in pharyngeal swallowing pressures is unknown. Read More

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September 2021

Early everolimus-facilitated reduced tacrolimus in liver transplantation: Results from the randomized HEPHAISTOS trial.

Liver Transpl 2021 Sep 15. Epub 2021 Sep 15.

Novartis Pharma GmbH, Nürnberg, Germany.

Background: Everolimus-facilitated reduced tacrolimus exposure (EVR+rTAC) at 30 days post-liver transplantation (LT) has shown advantages in renal preservation. This study evaluated the effects of early initiation of EVR+rTAC in de novo liver transplant recipients (LTR).

Methods: In HEPHAISTOS (NCT01551212, EudraCT 2011-003118-17), a 12-month (M), multicenter, controlled study, LTR were randomized at 7-21 days post-LT to receive EVR+rTAC or standard tacrolimus (sTAC), with steroids. Read More

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September 2021

Hydrokinetic pancreatic function and insulin secretion are moduled by Cl uniporter Slc26a9 in mice.

Acta Physiol (Oxf) 2021 Sep 15:e13729. Epub 2021 Sep 15.

Dept. of Gastroenterology, Hannover Medical School, Hannover, Germany.

Aim: Slc26a9 is a member of the Slc26 multifunctional anion transporter family. Polymorphisms in Slc26a9 are associated with an increased incidence of meconium ileus and diabetes in cystic fibrosis patients. We investigated the expression of Slc26a9 in the murine pancreatic ducts, islets and parenchyma, and elucidated its role in pancreatic ductal electrolyte and fluid secretion and endocrine function. Read More

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September 2021

The effects of pre-emptive intravenous ibuprofen on the thiol/disulfide homeostasis and C-reactive protein level as the markers of oxidative stress and inflammation during gynecologic laparoscopy: A randomized clinical trial.

Int J Clin Pract 2021 Sep 15:e14872. Epub 2021 Sep 15.

University of Health Sciences, Kartal Dr. Lütfi Kırdar City Hospital, The Department of Anesthesiology and Reanimation, Istanbul, Turkey.

Aims: In this study, we aimed to investigate the anti-inflammatory and antioxidant effects of intravenous ibuprofen by using the C-reactive protein level and thiol/disulfide homeostasis as the oxidative stress marker.

Materials And Methods: This study was conducted on 70 patients aged between 30 and 65 who were scheduled for elective laparoscopic hysterectomy. The patients were divided into two groups to receive either preemptive 800mg of intravenous ibuprofen plus 1000 mg of intravenous paracetamol (Group IP) or only 1000 mg of intravenous paracetamol as a control group (Group P). Read More

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September 2021

A prospective, randomized, controlled clinical study on the effectiveness of a single-use negative pressure wound therapy system, compared to traditional negative pressure wound therapy in the treatment of diabetic ulcers of the lower extremities.

Wound Repair Regen 2021 Sep 15. Epub 2021 Sep 15.

Global Data Analytics, Smith+Nephew, Hull, UK.

A multicenter, phase 4, randomized, comparative-efficacy study in subjects with lower extremity wounds was carried out to compare wound closure rates, for a single-use negative pressure wound therapy (s-NPWT) versus traditional NPWT (t-NPWT) systems over a 12-week treatment period. From the initial population of patients with diabetic foot ulcers (DFU) and venous leg ulcers (VLU), we analyzed a subgroup of patients with diabetes mellitus and leg and foot ulcers (either DFUs or VLUs in diabetics), termed, the diabetic lower extremity ulcers (DLEU). In the DLEU group, there were 95 patients in intention-to-treat (ITT) and 61 patients in per protocol (PP) populations, respectively. Read More

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September 2021

Phenotypic and Genotypic Characterization of Salmonella spp. Isolated from Foods Involved in Human Salmonellosis Outbreaks in Minas Gerais State, Brazil.

J Food Prot 2021 Sep 15. Epub 2021 Sep 15.

Fundacao Ezequiel Dias Rua Conde Pereira Carneiro, 80 BRAZIL Belo Horizonte Minas Gerais 30510-010 +55 31 98883-5638.

Salmonella spp. is one of the primary pathogens that cause foodborne diseases worldwide. In the present study, we deeply characterized Salmonella spp. Read More

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September 2021

Outcomes of Acute Lymphoblastic Leukemia with KMT2A (MLL) rearrangement - The MD Anderson Experience.

Blood Adv 2021 Sep 15. Epub 2021 Sep 15.

University of Texas M.D. Anderson Cancer Center, Houston, Texas, United States.

Acute lymphoblastic leukemia (ALL) with t(4;11)(q21;q23) - KMT2A-AFF1 is associated with a poor prognosis. The impact of KMT2A rearrangements other than t(4;11) is uncertain and the benefit of allogeneic stem cell transplant (HSCT) is unclear. We reviewed adult patients with ALL treated at our institution from 1984 to 2019 and identified 50/1102 (5%) with KMT2A rearrangement: 42 (84%) with t(4;11)/KMT2A-AFF1 and 8 (16%) with other gene partners. Read More

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September 2021

Theoretical assessment of Raman spectra on MXene TiC: from monolayer to bilayer.

Phys Chem Chem Phys 2021 Sep 15;23(35):19884-19891. Epub 2021 Sep 15.

Research Center for Advanced Information Materials (CAIM), Huangpu Research and Graduate School of Guangzhou University, Guangzhou 510555, China.

The structural, vibrational and Raman spectra properties of monolayer and bilayer TiC excited by two commonly used laser lines (532 nm and 633 nm) are investigated by first principles calculations to establish a correlation among layer stacks and optical features for two-dimensional MXenes. The stability of the monolayer and the energetically preferable stacking configuration are demonstrated by phonon dispersion. The monolayer and bilayer TiC systems are found to exhibit different point group symmetries and thereby the Raman properties due to the symmetry breaking of the bilayer structure caused by interlayer van der Waals interactions. Read More

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September 2021

Determining chemical exchange rate constants in nanoemulsions using nuclear magnetic resonance.

Phys Chem Chem Phys 2021 Sep 15;23(35):19244-19254. Epub 2021 Sep 15.

Department of Chemistry, University of Miami, Coral Gables, FL 33146, USA.

In this work, the second-order kinetics of molecules exchanging between chemically distinct microenvironments, such as those found in nanoemulsions, is studied using nuclear magnetic resonance (NMR). A unique aspect of NMR exchange studies in nanoemulsions is that the difference in molecular resonance frequencies between the two phases, which determines whether the exchange is fast, intermediate, or slow on the NMR timescale, can depend upon the emulsion droplet composition, which is also determined by the kinetic exchange constants themselves. Within the fast-exchange regime, changes in resonance frequencies and line widths with dilution were used to extract the exchange rate constants from the NMR spectra in a manner analogous to determining the kinetic parameters in NMR ligand binding experiments. Read More

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September 2021

Not just words! Effects of a light-touch randomized encouragement intervention on students' exam grades, self-efficacy, motivation, and test anxiety.

PLoS One 2021 15;16(9):e0256960. Epub 2021 Sep 15.

University of Szeged, Szeged, Huangary.

Motivated by the self-determination theory of psychology, we investigate how simple school practices can forge students' engagement with the academic aspect of school life. We carried out a large-scale preregistered randomized field experiment with a crossover design, involving all the students of the University of Szeged in Hungary. Our intervention consisted of an automated encouragement message that praised students' past achievements and signaled trust in their success. Read More

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September 2021

Circularly polarized optical microscope using a low aberration liquid crystal lens.

Opt Lett 2021 Sep;46(18):4434-4437

We demonstrate a circularly polarized optical microscope (POM) by incorporating a hole-patterned electrode (HPE) liquid crystal (LC) lens fabricated by photoalignment. The focal plane is controlled by voltages on the HPE LC lens with a tuning range of 2.2 mm without any mechanical movement. Read More

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September 2021

Association between Serum Uric Acid and Renal Outcome in Patients with Biopsy-confirmed Diabetic Nephropathy.

Endocr Connect 2021 Sep 1. Epub 2021 Sep 1.

F Liu, Division of Nephrology, Sichuan University West China Hospital, Chengdu, China.

Objective: To investigate the relationship between serum uric acid (SUA) level and renal outcome in patients with type 2 diabetes mellitus (T2DM) and diabetic nephropathy(DN).

Methods: A total of 393 Chinese patients with T2DM and biopsy-proven DN and followed at least one year were enrolled in this study. Patients were stratified by the quartiles of baseline level of SUA: Q1 group286. Read More

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September 2021

Primary vs. Specialist Care for Obstructive Sleep Apnea: A Systematic Review and Individual Participant Data Level Meta-Analysis.

Ann Am Thorac Soc 2021 Sep 15. Epub 2021 Sep 15.

IRBLLEIDA, 170673, Lleida, Spain.

Rationale: Primary care clinicians may be well placed to play a greater role in obstructive sleep apnea management.

Objectives: To evaluate the outcomes and cost-effectiveness of sleep apnea management in primary versus specialist care, using an individual-participant data meta-analysis to determine whether age, gender, severity of OSA and daytime sleepiness impacted outcomes.

Methods: Data sources were CINAHL, CENTRAL, MEDLINE Ovid SP, Scopus, ProQuest, US NIH Ongoing Trials Register, ISRCTN registry [inception until 09-25-2019]. Read More

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September 2021

Primary central pulmonary artery plasty for right atrial isomerism with pulmonary coarctation.

Asian Cardiovasc Thorac Ann 2021 Sep 15:2184923211045216. Epub 2021 Sep 15.

Department of Cardiovascular Surgery, 13761Mt. Fuji Shizuoka Children's Hospital, Shizuoka City, Japan.

Objective: Patients with unbalanced pulmonary artery growth resulting from pulmonary coarctation are considered unsuitable candidates for the Fontan procedure. Particularly, patients with right isomerism pose a challenge. We aimed to investigate the use of primary central pulmonary artery plasty at initial palliation in patients with right isomerism. Read More

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September 2021

Impact of Lipid Peroxidation on the Response of Cell Membranes to High-Speed Equibiaxial Stretching: A Computational Study.

J Phys Chem B 2021 Sep 15. Epub 2021 Sep 15.

Institute of Chemical Materials, China Academy of Engineering and Physics, Mianyang 621900, China.

The difference between diseased and healthy cellular membranes in response to mechanical stresses is crucial for biology, as well as in the development of medical devices. However, the biomolecular mechanisms by which mechanical stresses interact with diseased cellular components remain largely unknown. In this work, we focus on the response of diseased cellular membranes with lipid peroxidation to high-speed tensile loadings. Read More

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September 2021

Efficacy and safety of electrical stimulation in the treatment of neurogenic bladder dysfunction in myelomeningocele-Systematic review of randomized clinical trials.

Neurourol Urodyn 2021 Sep 15. Epub 2021 Sep 15.

Postgraduate Program in Rehabilitation Sciences, Universidade Nove de Julho (UNINOVE), São Paulo, Brazil.

Aims: The purpose of this systematic review was to investigate and synthesize the effects (benefits and harms) of electrical stimulation (EE), alone or in association with other interventions, compared with sham and other interventions, for the treatment of neurogenic bladder dysfunction in myelomeningocele.

Methods: This systematic review was conducted following the methodological recommendations of the Cochrane Handbook for Systematic Reviews of Interventions and registered at PROSPERO (CRD42020200425). A search was performed in the following electronic databases: MEDLINE, Cochrane Central Register of Controlled Trials, EMBASE, LILACS, and PEDro. Read More

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September 2021

Biomonitoring of metallic air pollutants in unique habitations of the Brahmaputra Valley using moss species-Atrichum angustatum: spatiotemporal deposition patterns and sources.

Environ Sci Pollut Res Int 2021 Sep 15. Epub 2021 Sep 15.

Department of Environmental Science, Tezpur University, Tezpur, 784028, India.

In this paper, we have evaluated the bioaccumulation of metals by Atrichum angustatum, which is a readily available moss species in the Brahmaputra valley, India. A systematic investigation of metallic pollutants in the atmosphere was carried out using A. angustatum as a biomonitor collected from representative locations during three seasons viz. Read More

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September 2021

The Assessment of Functional Movement in Children and Adolescents: A Systematic Review and Meta-Analysis.

Sports Med 2021 Sep 15. Epub 2021 Sep 15.

School of Public Health, Physiotherapy and Sports Science, University College Dublin, Dublin, Ireland.

Background: The Functional Movement Screen™ (FMS™) is an assessment of human movement that may signal potential deficits that could predispose an otherwise healthy person to injury risk. FMS™ scores are well reported in both athletic and adult samples. However, to date, there has been no comprehensive systematic review and meta-analysis of FMS™ data among school-aged children and adolescents. Read More

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September 2021

Hyperparathyroidism in patients with overt and mild primary aldosteronism.

Hormones (Athens) 2021 Sep 15. Epub 2021 Sep 15.

Unit of Endocrinology and Diabetes Centre, General Hospital of Athens "G Gennimatas", 154 Mesogeion Avenue, 11527, Athens, Greece.

Introduction: Increased prevalence of hyperparathyroidism (HP) has been observed in primary aldosteronism (PA) patients. However, HP prevalence in milder forms of PA has not to date been evaluated.

Objectives: The objectives of this study were to assess the prevalence of primary and secondary HP in overt and milder misdiagnosed cases of PA and to investigate the effect of treatment on parathormone (PTH) secretion. Read More

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September 2021

Biogas and Volatile Fatty Acid Production During Anaerobic Digestion of Straw, Cellulose, and Hemicellulose with Analysis of Microbial Communities and Functions.

Appl Biochem Biotechnol 2021 Sep 15. Epub 2021 Sep 15.

China Urban Construction Design & Research Institute, No.36, Deshengmenwai Street, Beijing, China.

The anaerobic digestion efficiency and methane production of straw was limited by its complex composition and structure. In this study, rice straw (RS), cellulose, and hemicellulose were used as raw materials to study biogas production performance and changes in the volatile fatty acids (VFAs). Further, microbial communities and genetic functions were analyzed separately for each material. Read More

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September 2021

Morphological, Biochemical, and Proteomic Studies Revealed Impact of Fe and P Crosstalk on Root Development in Phaseolus vulgaris L.

Appl Biochem Biotechnol 2021 Sep 15. Epub 2021 Sep 15.

Division of Agricultural Statistics, Sher-E-Kashmir University of Agricultural Sciences & Technology of Kashmir, Shalimar, Srinagar, Jammu & Kashmir, India.

Mineral stress is one of the major abiotic stresses faced by crop plants. The present study was undertaken to investigate the impact of mineral stress (iron (Fe) and phosphorus (P)) on various morphological and biochemical responses of the shoot and root tissues and root architecture of common bean (Phaseolus vulgaris L.). Read More

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September 2021