79,574 results match your criteria diet prevention

Physiological effects of nutrients on insulin release by pancreatic beta cells.

Mol Cell Biochem 2021 Apr 12. Epub 2021 Apr 12.

Grupo de investigación en Biología celular y funcional e ingeniería de biomoléculas, Universidad Antonio Nariño-Sede Circunvalar. Cra, 3 Este # 47A - 15, Bl 5, Bogotá, Colombia.

Obesity and type 2 diabetes (T2D) are growing health problems associated with a loss of insulin sensitivity. Both conditions arise from a long-term energy imbalance, and frequently, lifestyle measures can be useful in its prevention, including physical activity and a healthy diet. Pancreatic β-cells are determinant nutrient sensors that participate in energetic homeostasis needs. Read More

View Article and Full-Text PDF

"My coupons are like gold": experiences and perceived outcomes of low-income adults participating in the British Columbia Farmers' Market Nutrition Coupon Program.

Public Health Nutr 2021 Apr 12:1-30. Epub 2021 Apr 12.

Faculty of Kinesiology, University of Calgary, 2500 University Drive NW, Calgary, ABT2N 1N4, Canada.

Objective: The British Columbia Farmers' Market Nutrition Coupon Program (FMNCP) provides low-income households with coupons valued at $21/week for 16 weeks to purchase healthy foods in farmers' markets. Our objective was to explore FMNCP participants' experiences of accessing nutritious foods, and perceived program outcomes.

Design: This study used qualitative description methodology. Read More

View Article and Full-Text PDF

Associations of behaviors, biological phenotypes and cardiovascular health with risks of stroke and stroke subtypes: A prospective cohort study.

EClinicalMedicine 2021 Mar 18;33:100791. Epub 2021 Mar 18.

School of Public Health, Tianjin Medical University, Tianjin, China.

Background: Although many cardiovascular risk factors for stroke have been reported before, it has not been investigated comprehensively for all major stroke types in large datasets. This study aimed to evaluate the associations of healthy behaviors, biological phenotypes and cardiovascular health (CVH) with long-term risks of strokes events, overall and stroke subtypes (ischemic stroke [IS], intracerebral hemorrhage [ICH], subarachnoid hemorrhage [SAH], and unspecified stroke).

Methods: Between 2006 and 2010, a total of 354,976 participants (age 40-70 years) in the UK Biobank free of stroke and coronary heart disease were examined and thereafter followed up to 2020. Read More

View Article and Full-Text PDF

Results of a prospective cardiovascular disease prevention program.

Prev Med Rep 2021 Jun 12;22:101344. Epub 2021 Mar 12.

Cardiovascular Health Program Registry, Henry M. Jackson Foundation for the Advancement of Military Medicine, 6720A Rockledge Drive, Bethesda, MD 20817, United States.

The Cardiovascular Health Program (CHP) Registry is a 12-month, prospective study of therapeutic lifestyle change (TLC). Adult participants received comprehensive assessment of health behaviors and cardiovascular disease (CVD) risk factors. Personalized TLC action plans addressed modifiable health behaviors for diet, exercise, stress management, and sleep. Read More

View Article and Full-Text PDF

Dynamics of hepatic steatosis resolution and changes in gut microbiome with weight loss in nonalcoholic fatty liver disease.

Obes Sci Pract 2021 Apr 4;7(2):217-225. Epub 2021 Jan 4.

Cancer Epidemiology and Prevention Program University of Pittsburgh Medical Center Hillman Cancer Center Pittsburgh Pennsylvania USA.

Background: Weight loss is recommended as the primary treatment for nonalcoholic fatty liver disease (NAFLD). However, the magnitude and velocity of hepatic steatosis resolution with weight loss is unclear, making it difficult to counsel patients seeking weight loss for treatment of NAFLD. The aim of this study was to determine the rate of hepatic steatosis improvement and stool microbiome changes associated with rapid diet-induced weight loss in NAFLD. Read More

View Article and Full-Text PDF

Unbalanced intakes of sodium and potassium among Tunisian adults: A cross-sectional study.

Food Sci Nutr 2021 Apr 26;9(4):2234-2246. Epub 2021 Feb 26.

Laboratory Materials Molecules and Applications LR11ES22 Tunis Tunisia.

The prevention and management of hypertension are untimely associated with a lowering of sodium intake. The present study aimed to evaluate the sodium and potassium intake levels of Tunisian population through measurement of 24-hr urinary sodium excretions. A randomly, multistage, cross-sectional study was conducted in an urban region (Bizerte) in Tunisia during 2015. Read More

View Article and Full-Text PDF

What people really change after genetic testing (GT) performed in private labs: results from an Italian study.

Eur J Hum Genet 2021 Apr 12. Epub 2021 Apr 12.

Applied Research Division for Cognitive and Psychological Science, European Institute of Oncology (IEO), IRCCS, Milan, Italy.

Despite the widespread diffusion of direct-to-consumer genetic testing (GT), it is still unclear whether people who learn about their genetic susceptibility to a clinical condition change their behaviors, and the psychological factors involved. The aim of the present study is to investigate long-term changes in health-related choices, individual tendencies and risk attitudes in an Italian sample of GT users. In the context of the Mind the Risk study, which investigated a sample of Italian adults who underwent GT in a private laboratory, 99 clients participated in the follow up assessment. Read More

View Article and Full-Text PDF

A New Score for Quantifying Adherence to a Cancer-Preventive Mediterranean Diet.

Nutr Cancer 2021 Apr 10:1-13. Epub 2021 Apr 10.

Department Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA.

Herein a Mediterranean Cancer Preventive Diet Score (MCAP Score) is proposed to quantify adherence to both traditional Mediterranean fat intakes and the current dietary recommendations for cancer prevention. The scoring uses research-backed cutoff values, unlike other scores that are based on a population-specific median value. The MCAP score awards positive points for seven preventive food categories, including Mediterranean fats (monounsaturated fats, ω-3 fatty acids) associated with reduced adiposity, and negative points for four food categories associated with increased cancer risk, including ultra-processed foods. Read More

View Article and Full-Text PDF

Self-Efficacy for Healthy Eating Moderates the Impact of Stress on Diet Quality Among Family Child Care Home Providers.

J Nutr Educ Behav 2021 Apr;53(4):309-315

Department of Nutrition, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC; Center for Health Promotion and Disease Prevention, University of North Carolina at Chapel Hill, Chapel Hill, NC. Electronic address:

Objective: To examine associations of stress and sleep with diet quality of family child care home (FCCH) providers, and whether self-efficacy for healthy eating influences these associations.

Design: A cross-sectional analysis was performed using baseline data (2013-2015) from a randomized control trial with FCCH providers.

Participants: The study included 166 licensed FCCH providers, aged >18 years, from central North Carolina. Read More

View Article and Full-Text PDF

Dietary total antioxidant capacity is inversely associated with cardiovascular events and cardiometabolic risk factors: A cross-sectional study.

Nutrition 2021 Feb 19;89:111140. Epub 2021 Feb 19.

Laboratory of Energy Metabolism and Body Composition, Department of Nutrition and Health, Universidade Federal de Viçosa, Viçosa, Minas Gerais, Brazil. Electronic address:

Objectives: Dietary total antioxidant capacity (dTAC) has been introduced as a useful tool to quantify the antioxidant content of a diet. However, few studies have evaluated the association of dTAC with cardiovascular disease (CVD) occurrence and cardiometabolic risk factors in people with established CVD events. Thus, we aimed to investigate the presence of an association between dTAC values, cardiovascular events, and cardiometabolic risk factors in individuals with previous CVD in a Brazilian multicenter study. Read More

View Article and Full-Text PDF
February 2021

Developing a realist informed framework for cultural adaptation of lifestyle interventions for the prevention of type 2 diabetes in South Asian populations in Europe.

Diabet Med 2021 Apr 10:e14584. Epub 2021 Apr 10.

Usher Institute, University of Edinburgh, Edinburgh, United Kingdom.

Aims: Selected lifestyle interventions proven effective for White-European populations have been culturally adapted for South Asian populations living in Europe, who are at higher risk of type 2 diabetes. However, a limited theoretical basis underpins how cultural adaptations are believed to augment intervention effectiveness. We undertook a realist review to synthesise existing literature on culturally adapted type 2 diabetes prevention interventions, to develop a framework that shows 'how' cultural adaptation works, for 'whom' and in 'what contexts'. Read More

View Article and Full-Text PDF

Efficacy of tailored recommendations to promote healthy lifestyles: a post hoc analysis of a randomized controlled trial.

Transl Behav Med 2021 Apr 10. Epub 2021 Apr 10.

Cardiovascular Epidemiology and Genetics Research Group, IMIM-Hospital del Mar Research Institute, 08003 Barcelona, Spain.

Prevention is the key to stopping the ravages of cardiovascular diseases, the main cause of death worldwide. The objective was to analyze the efficacy of tailored recommendations to promote healthy lifestyles. Parallel-arm randomized controlled trial with 1 year follow-up. Read More

View Article and Full-Text PDF

Effectiveness of tailored intervention with a salutogenic approach to improve adherence in adults with hypertension: a non-randomized trial.

Eur J Cardiovasc Nurs 2021 Apr 9. Epub 2021 Apr 9.

Faculty of Nursing, Universidad de Antioquia, Cl. 64 #53-09, Medellín, 050010, Colombia.

Aims: Hypertension (HTN) is a chronic long-term, slowly progressing disease. For HTN control, management, and prevention of associated complications, adequate adherence to treatment is required. It has been proposed that tailored interventions to individual needs are required to address the phenomenon of adherence to treatment. Read More

View Article and Full-Text PDF

Improving cardiorespiratory fitness protects against inflammation in children: the IDEFICS study.

Pediatr Res 2021 Apr 9. Epub 2021 Apr 9.

GENUD (Growth, Exercise, Nutrition and Development) Research Group, University of Zaragoza, Zaragoza, Spain.

Background: Muscular and cardiorespiratory fitness (MF and CRF) have been related to inflammation. Thus, the aim of this study was to assess the relationship between fitness and high-sensitivity C-reactive protein (hs-CRP) in European children both in the cross-sectional and longitudinal analysis.

Methods: Three hundred and fifty-seven children (46. Read More

View Article and Full-Text PDF

[Impact of nutritional factors during and after cancer].

Bull Cancer 2021 Apr 6. Epub 2021 Apr 6.

Cellule de coordination, domaine de Vilvert, réseau national alimentation cancer recherche (Réseau NACRe), 78350 Jouy-en-Josas, France.

Nutritional factors (diet, weight, alcohol, physical activity) are identified as factors having an impact on the onset of several cancer sites. Less abundant scientific data also underline their impact on the tumor progression. A review of the scientific literature was carried out by a group of experts established by the French National Cancer Institute (INCa) to better document the influence of nutritional factors during and after cancer on outcomes such as overall mortality, cancer specific mortality, recurrence, second primary cancers and quality of life. Read More

View Article and Full-Text PDF

Effects of High-Fructose Diet . Teklad Diet in the MNU-Induced Rat Mammary Cancer Model: Altered Tumorigenesis, Metabolomics and Tumor RNA Expression.

J Obes Chronic Dis 2021 11;5(1):67-78. Epub 2021 Jan 11.

Chemopreventive Agent Development Research Group, Division of Cancer Prevention, Rockville, MD.

Epidemiology, clinical and experimental animal studies suggest high fructose diets are detrimental to metabolic status and may contribute to tumor development. This due to increased obesity and metabolic syndrome, known risk factors for many types of cancer. We compared tumor development in N-methyl-N-nitrosourea (MNU)-treated rats fed either a high (60%)-fructose diet (HFD) or a standard diet (SD). Read More

View Article and Full-Text PDF
January 2021

Ambulatory Patients with Cardiometabolic Disease and Without Evidence of COVID-19 During the Pandemic. The CorCOVID LATAM Study.

Glob Heart 2021 02 17;16(1):15. Epub 2021 Feb 17.

Queen's University, CA.

Background: SARS-CoV-2 pandemic has modified the cardiovascular care of ambulatory patients. The aim of this survey was to study changes in lifestyle habits, treatment adherence, and mental health status in patients with cardiometabolic disease, but no clinical evidence of COVID-19.

Methods: A cross-sectional survey was conducted in ambulatory patients with cardiometabolic disease using paper/digital surveys. Read More

View Article and Full-Text PDF
February 2021

Expert Consensus on Telemedicine Management of Diabetes (2020 Edition).

Bo Zhang

Int J Endocrinol 2021 24;2021:6643491. Epub 2021 Mar 24.

Department of Endocrinology, China-Japan Friendship Hospital, Beijing 100029, China.

Diabetes is a chronic disease that is very suitable for telemedicine management. Owing to the coronavirus disease 2019 (COVID-19) pandemic, telemedicine management of diabetes is particularly important. This consensus proposes 38 recommendations for key issues in telemedicine management of diabetes and provides preliminary specifications for diabetes management. Read More

View Article and Full-Text PDF

Change in dietary inflammatory index score is associated with control of long-term rheumatoid arthritis disease activity in a Japanese cohort: the TOMORROW study.

Arthritis Res Ther 2021 04 8;23(1):105. Epub 2021 Apr 8.

Shirahama Foundation for Health and Welfare, Search Institute for Bone and Arthritis Disease (SINBAD), Nishimuro-gun, Shirahama-cho 1447, Wakayama, 649-2211, Japan.

Background: The dietary inflammatory index (DII®), a quantitative measure of the inflammatory potential of daily food and nutrient intake, and associations between a variety of health outcomes have been reported. However, the association between DII score and disease activity of rheumatoid arthritis (RA) is unclear. Therefore, this study was designed to test whether higher DII score contributes to disease activity and as a corollary, whether reducing DII score helps to achieve or maintain low disease activity or remission in patients with RA. Read More

View Article and Full-Text PDF

Mild exacerbation of obesity- and age-dependent liver disease progression by senolytic cocktail dasatinib + quercetin.

Cell Commun Signal 2021 Apr 8;19(1):44. Epub 2021 Apr 8.

International Clinical Research Center, St. Anne's University Hospital, Brno, Czech Republic.

Background: Nonalcoholic fatty liver disease (NAFLD) is increasingly prevalent and represents a growing challenge in terms of prevention and treatment. A minority of affected patients develops inflammation, subsequently fibrosis, cirrhosis and hepatocellular carcinoma (HCC). HCC is a leading cause of cancer-related death. Read More

View Article and Full-Text PDF

Factors associated with the progression and prevention of noncommunicable diseases in community-dwelling Filipino adults: A cross-sectional study.

Medicine (Baltimore) 2021 Apr;100(14):e25082

Department of Public Health, Kobe University Graduate School of Health Sciences, Kobe, Japan.

Abstract: Noncommunicable diseases (NCDs) are an important cause of disability and death in Muntinlupa, Manila, Philippines. However, there is little community-based research on lifestyle behaviors that affect the progression of NCDs or on the hindrances to NCD prevention.This cross-sectional study investigated the lifestyle behaviors associated with the progression and prevalence of NCDs and clarified factors associated with health promotion for the NCDs prevention among 168 Filipino adults aged 50 years and above in the community setting. Read More

View Article and Full-Text PDF

A Systematic Review of the Association Between Vegan Diets and Risk of Cardiovascular Disease.

J Nutr 2021 Apr 8. Epub 2021 Apr 8.

Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, Strangeways Research Laboratory, Cambridge, United Kingdom.

Background: Plant-based diets are gaining attention globally due to their environmental benefits and perceived health-protective role. A vegan diet may have cardiovascular benefits; however, evidence remains conflicting and insufficiently assessed.

Objectives: We evaluated the utility of the vegan diet in cardiovascular disease (CVD) prevention. Read More

View Article and Full-Text PDF

The effect of intermittent energy restriction on weight loss and diabetes risk markers in women with a history of gestational diabetes: a 12-month randomized control trial.

Am J Clin Nutr 2021 Apr 8. Epub 2021 Apr 8.

University of South Australia, Clinical and Health Sciences, Adelaide, Australia.

Background: Weight loss after gestational diabetes (GDM) can prevent or delay the onset of type 2 diabetes. Intermittent energy restriction (IER) may offer an alternative to continuous energy restriction (CER) for weight loss.

Objectives: We compared the effects of IER (2 days per week) to daily CER over 12 mo on weight loss and diabetes risk markers in overweight women with previous GDM. Read More

View Article and Full-Text PDF

SNF5 promotes IL-1β Expression via H3K4me1 in Atherosclerosis induced by Homocysteine.

Int J Biochem Cell Biol 2021 Apr 5:105974. Epub 2021 Apr 5.

School of Basic Medical Sciences, Ningxia Medical University, Yinchuan, 750004, China; NHC Key Laboratory of Metabolic Cardiovascular Diseases Research, Ningxia Medical University, Yinchuan, 750004, China; Ningxia Key Laboratory of Vascular Injury and Repair Research, Ningxia Medical University, Yinchuan, 750004, China. Electronic address:

Homocysteine (Hcy) is a strong and independent risk factor of atherosclerosis. It can accelerate atherosclerosis through increased production of inflammatory factors, especially interleukin-1 β (IL-1β), while the precise mechanisms remain to be well elucidated. In this study, we investigated the role of the tumor suppressor gene SNF5 related to Switch/Sucrose Non-Fermentable complex (SWI/SNF) in the occurrence and development of atherosclerosis induced by Hcy. Read More

View Article and Full-Text PDF

In silico analysis of the potential mechanism of a preventive Chinese medicine formula on Coronavirus Disease 2019.

J Ethnopharmacol 2021 Apr 5:114098. Epub 2021 Apr 5.

Provincial Key Laboratory of TCM Diagnostics, Hunan University of Chinese Medicine, Changsha, China; Hunan Engineering Technology Research Center for Medicinal and Functional Food, Hunan University of Chinese Medicine, Changsha, China; Key Laboratory of TCM Heart and Lung Syndrome Differentiation &; Medicated Diet and Dietotherapy, Hunan University of Chinese Medicine, Changsha, China. Electronic address:

Ethnopharmacological Relevance: With the spread of Coronavirus Disease 2019 (COVID-19), combination with traditional Chinese medicine (TCM) has been widely used as a prevention and therapy strategy in China. Xin guan No.1 (XG-1) prescription is a preventive formula recommended by the Hunan Provincial Administration of TCM to prevent the pandemic of COVID-19. Read More

View Article and Full-Text PDF

Dietary Selenium Requirement for the Prevention of Glucose Intolerance and Insulin Resistance in Middle-Aged Mice.

J Nutr 2021 Apr 8. Epub 2021 Apr 8.

Department of Food Science, Nutrition, and Health Promotion, Mississippi State University, Mississippi State, MS, USA.

Background: Although dietary selenium (Se) deficiency or excess induces type 2 diabetes-like symptoms in mice, suboptimal body Se status usually causes no symptoms but may promote age-related decline in overall health.

Objectives: We sought to determine the dietary Se requirement for protection against type 2 diabetes-like symptoms in mice.

Methods: Thirty mature (aged 4 mo) male C57BL/6J mice were fed a Se-deficient torula yeast AIN-93M diet supplemented with Na2SeO4 in graded concentrations totaling 0. Read More

View Article and Full-Text PDF

Trend of Carcinoma of the Stomach in Relation to Site, Age and Aetiology: Study of 112 Cases in a Tertiary Level Hospital.

Mymensingh Med J 2021 Apr;30(2):395-401

Dr Mukti Mahamud, Assistant Professor, Surgery, Sheikh Hasina Medical College, Jamalpur, Bangladesh E-mail:

Stomach cancer is the fourth most common cancer worldwide, but due to its poor prognosis, it is the second most common cause of cancer deaths worldwide. The incidence of carcinoma of gastric cardia is found to be increasing, while that of the antrum is seen to be decreasing. Data from Bangladesh is lacking on this aspect. Read More

View Article and Full-Text PDF

[Hypothesis regarding the connections between severe COVID-19 in children and nutrition: a narrative review].

Nutr Hosp 2021 Apr 8. Epub 2021 Apr 8.

Department of Research Methodology. Instituto Nacional de Pediatría.

Coronavirus disease 2019 (COVID-19) is caused by severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2). Compared with adults, children with SARS-CoV-2 infection may have fewer and less severe symptoms. Gastrointestinal symptoms are commonly reported in children, sometimes as the only manifestation of the disease, and most often manifest as anorexia, diarrhea, nausea and vomiting, or abdominal pain. Read More

View Article and Full-Text PDF

A comparison of complementary measures of vitamin B6 status, function, and metabolism in the European Prospective Investigation into Cancer and Nutrition (EPIC) study.

Am J Clin Nutr 2021 Apr 7. Epub 2021 Apr 7.

Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom.

Background: Vitamin B6 insufficiency has been linked to increased risk of cancer and other chronic diseases. The circulating concentration of pyridoxal 5'-phosphate (PLP) is a commonly used measure of vitamin B6 status. Ratios of substrates indicating PLP coenzymatic function and metabolism may be useful complementary measures to further explore the role of vitamin B6 in health. Read More

View Article and Full-Text PDF

Towards refining WCRF/AICR cancer prevention recommendations for red and processed meat intake: Insights from Alberta's Tomorrow Project cohort.

Br J Nutr 2021 Apr 8:1-38. Epub 2021 Apr 8.

MAP Centre for Urban Health Solutions, Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, Canada.

Current cancer prevention recommendations advise limiting red meat intake to <500g/week and avoiding consumption of processed meat, but do not differentiate the source of processed meat. We examined the associations of processed meat derived from red vs. non-red meats with cancer risk in a prospective cohort of 26,218 adults who reported dietary intake using the Canadian Diet History Questionnaire. Read More

View Article and Full-Text PDF