1,327 results match your criteria dichorionic twin


Vitamin D status in women with dichorionic twin pregnancies and their neonates: a pilot study in China.

BMC Pregnancy Childbirth 2021 Apr 8;21(1):279. Epub 2021 Apr 8.

International Collaborative Laboratory of Reproduction and Development of Chinese Ministry of Education, Chongqing Medical University, Chongqing, 400016, China.

Background: Vitamin D deficiency is a global public health issue in women and children and is associated with adverse impacts on child growth, such as rickets. However, prior studies have mainly focused on measuring vitamin D levels in singleton pregnant women and their offspring, and very limited studies have revealed the prevalence of vitamin D deficiency in twin pregnant women and their offspring. The aim of this study was to investigate vitamin D levels in twin-pregnant women and their neonates. Read More

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Pathologic Basis for the Definition of Discordant Growth in Dichorionic Twins.

Fetal Diagn Ther 2021 Mar 29:1-9. Epub 2021 Mar 29.

Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada.

Objective: The aim of the current study was to identify the optimal cutoff that should define discordance in dichorionic twin gestations through correlation with abnormal placental pathology as a specific measure of fetal growth restriction of the smaller twin.

Methods: We performed a retrospective cohort study of all women with dichorionic twin pregnancies who gave birth in a single center between 2002 and 2015. We investigated the association between the level of growth discordance and maternal vascular malperfusion (MVM) pathology in the placenta of the smaller twin, with and without adjustment for whether the smaller twin is small for gestational age (SGA). Read More

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Elective Fetal Reduction in Dichorionic Diamniotic Twin Pregnancies on Parental Request: A Single-Centre Experience.

Fetal Diagn Ther 2021 Mar 29:1-7. Epub 2021 Mar 29.

Department of Fetal Medicine and Genetics, Indraprastha Apollo Hospitals, New Delhi, India.

Objectives: Our study aimed to examine a subset of electively reduced twins and compare their outcomes with those of expectantly managed twins, along with a cohort of singleton pregnancies. The secondary aim was to ascertain the procedure-related miscarriage risks.

Methods: A retrospective cohort analysis was performed at Apollo Centre for Fetal Medicine, New Delhi, comparing pregnancy outcomes in dichorionic diamniotic twin pregnancies which were reduced to singletons (group 1) with that of women with dichorionic twins managed expectantly (group 0) and women with a singleton pregnancy (group 2). Read More

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Twin Anemia Polycythemia Sequence in a Dichorionic Twin Pregnancy Leading to Severe Cerebral Injury in the Recipient.

Fetal Diagn Ther 2021 Mar 26:1-6. Epub 2021 Mar 26.

Department of Pediatrics, Leiden University Medical Center, Leiden, The Netherlands.

Twin anemia polycythemia sequence (TAPS) is a form of chronic imbalanced feto-fetal transfusion through minuscule placental anastomoses leading to anemia in the TAPS donor and polycythemia in the TAPS recipient and has been reported only in monochorionic twins. We report a very unusual case of TAPS which developed in a dichorionic twin pair, born at a gestational age of 33+2. Twin 1 (recipient) was polycythemic and had a hemoglobin value of 22. Read More

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DICHORIONIC TWIN-SPECIFIC VERSUS SINGLETON GROWTH REFERENCES FOR DIAGNOSIS OF FETAL GROWTH RESTRICTION.

Am J Obstet Gynecol 2021 Mar 23. Epub 2021 Mar 23.

Department of Obstetrics and Gynecology, Division of Maternal-Fetal Medicine, The Medical University of South Carolina, Charleston, SC.

Background: Fetal growth restriction (FGR) is associated with an increased risk of adverse neonatal outcomes. The Hadlock singleton growth reference is widely used to determine estimated fetal weight (EFW) percentile in both twin and singleton gestations. The NICHD twin-specific growth reference accounts for the different growth trajectory that twins follow during pregnancy. Read More

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Case of fetal ovarian juvenile granulosa cell tumor: Complications and management.

J Obstet Gynaecol Res 2021 Mar 23. Epub 2021 Mar 23.

The Ruth and Bruce Rappaport Faculty of Medicine, Technion, Haifa, Israel.

A prenatal ovarian juvenile granulosa cell tumor (JGCT) is a rare entity which may present as an intra-abdominal cyst. Due to its low incidence, optimal management and timing for intervention remain uncertain. This report presents a case of an intra-abdominal cystic structure in a female fetus, one of the two fetuses in a dichorionic-diamniotic twin pregnancy, detected during routine fetal sonographic surveillance at 30 weeks of gestation. Read More

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Perinatal Outcome of Selective Intrauterine Growth Restriction in Monochorionic Twins: Evaluation of a Retrospective Cohort in a Developing Country.

Twin Res Hum Genet 2021 Mar 22:1-5. Epub 2021 Mar 22.

Department of Obstetrics, Instituto Nacional de Saúde da Mulher, da Criança e do Adolescente Fernandes Figueira, Fundação Oswaldo Cruz (IFF/Fiocruz), Rio de Janeiro, Brazil.

Selective intrauterine growth restriction (sIUGR) in monochorionic twin pregnancies is associated with greater morbidity and mortality for both fetuses when compared to singleton and dichorionic pregnancies. This retrospective cohort study aimed to assess the perinatal outcomes of monochorionic twin pregnancies affected by this disorder and conducted expectantly, by analyzing the results according to the end-diastolic flow in the umbilical artery Doppler of the smaller twin (type I: persistently forward/type II: persistently absent or reversed/type III: intermittently absent or reversed). Seventy-five monochorionic diamniotic twin pregnancies with sIUGR were included in this study. Read More

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A 34-Year-Old Woman with a Diamniotic Dichorionic Twin Pregnancy Presenting with an Erythematous and Papular Skin Rash Associated with SARS-CoV-2 Infection.

Am J Case Rep 2021 Mar 20;22:e929489. Epub 2021 Mar 20.

Department of Infectious Diseases, National Institute of Respiratory Diseases (INER), Mexico City, Mexico.

BACKGROUND The damage caused by the severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) has been extensive. Pregnant women are a group requiring special attention in medicine given the anatomical and physiological changes that occur during pregnancy. Skin rash is commonly associated with pregnancy, with the most common form of an erythematous maculopapular rash being pruritic urticarial papules and plaques of pregnancy. Read More

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Spontaneous fundal uterine rupture in a non-labouring 31-week twin pregnancy and unknown previous hysteroscopic adhesiolysis: A case report.

Case Rep Womens Health 2021 Apr 27;30:e00302. Epub 2021 Feb 27.

Gloucestershire NHS Foundation Trust, Gloucester Royal Hospital, Great Western Road, Gloucester, GL1 3NN.

A 46-year-old woman presented at 31 weeks of gestation with a twin pregnancy (dichorionic, diamniotic) and with mild abdominal pain, not in labour, leading to complete spontaneous fundal uterine rupture. She underwent prompt surgical intervention and resuscitation with packed red cells, cell-salvage blood and fresh frozen plasma (FFP). Twin 1 survived and twin 2 died. Read More

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Twin discordance: a study of volumetric fetal brain MRI and neurodevelopmental outcome.

Eur Radiol 2021 Mar 16. Epub 2021 Mar 16.

Department of Obstetrics and Gynecology, Chaim Sheba Medical Center, Tel-Hashomer, 52621, Ramat Gan, Israel.

Objective: This study employed magnetic resonance imaging (MRI) to compare brain volumes of discordant twins and examined their neurodevelopment after birth by using a validated exam.

Study Design: A prospective historical cohort study of discordant dichorionic diamniotic (DCDA) or monochorionic diamniotic (MCDA) twin fetuses, who undergone an MRI scan to evaluate growth restriction in the discordant twin (weight < 10 centile) during 6 years period, at a single tertiary center. Twenty-seven twin pairs were included in the volumetric study and 17 pairs were included in the neurodevelopmental outcome examination. Read More

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Predictive Accuracy of Singleton Versus Customized Twin Growth Chart for Adverse Perinatal Outcome: A Cohort Study.

Int J Environ Res Public Health 2021 Feb 19;18(4). Epub 2021 Feb 19.

Department of Obstetrics and Gynecology, Medical University of Warsaw, Starynkiewicza Square 1/3, 02-015 Warsaw, Poland.

Background: Fetal growth of twins differs from singletons. The objective was to assess the fetal growth in twin gestations in relation to singleton charts and customized twin charts, respectively, followed by a comparison of the frequency of neonatal complications in small-for-gestational-age (SGA) twins.

Methods: We performed an analysis of twin pregnancies with established chorionicity with particular emphasis on postnatal adverse outcomes in newborns classified as SGA. Read More

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February 2021

Twin pregnancies.

Ultraschall Med 2021 Feb 23. Epub 2021 Feb 23.

Department of Obstetrics, University Hospital Zürich and University of Zurich, Zurich, Switzerland.

Twin pregnancies, resulting in 2-3 % of all deliveries, are high risk pregnancies which need specialized care. A correct dating of pregnancy and the assessment of the chorionicity/amnionicity in the first trimester (< = 13 + 6 gestational weeks, GW) is essential for further monitoring. During first trimester risk stratification of monochorionic pregnancies includes evaluation of discordance of crown-rump-lengths, nuchal translucencies and amniotic fluid. Read More

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February 2021

The Accuracy of Sonographic Fetal Head Circumference in Twin Pregnancies.

J Obstet Gynaecol Can 2021 Feb 20. Epub 2021 Feb 20.

Department of Obstetrics and Gynecology, Hillel Yaffe Medical Center, Hadera, Israel; The Rappaport Faculty of Medicine, Technion, Haifa, Israel.

Objective: To assess the accuracy of sonographic estimation of fetal head circumference in twin gestations.

Methods: A retrospective analysis of sonographic evaluations of twin gestations >34 weeks, performed within 7 days of delivery, in a single university-affiliated medical centre. Sonographic head circumference was compared with neonatal head circumference. Read More

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February 2021

[Pregnancy and Hemodialysis: About a Successful Twin Pregnancy].

Acta Med Port 2021 Jan 4;34(1):56-58. Epub 2021 Jan 4.

Departamento de Obstetrícia A. Maternidade Doutor Daniel de Matos. Centro Hospitalar e Universitário de Coimbra. Coimbra. Portugal.

Pregnancy is a rare condition in women with chronic kidney disease on hemodialysis, but its incidence has increased in recent years. Despite being a high-risk condition for both mother and fetus, there has been an improvement in care due to the increased number of cases described and the experience gained in dialysis therapy. We report the case of a multiparous 32-years-old women with chronic hypertension and chronic kidney disease with 10 years of evolution and difficult control, with a diagnosis of dichorionic/diamniotic twin pregnancy, 4 months after beginning hemodialysis. Read More

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January 2021

Pregnancy and neonatal outcomes of twin pregnancies - the role of maternal age.

J Perinat Med 2021 Feb 17. Epub 2021 Feb 17.

The Department of Obstetrics and Gynecology, Chaim Sheba Medical Center, Ramat-Gan, Israel.

Objectives: We aim to study the association of maternal age with maternal and neonatal complications in twin pregnancies.

Methods: A retrospective cohort study of dichorionic-diamniotic twin pregnancies stratified into three groups according to maternal age ("A" <25, "B" 25-34 and "C" 35-44 years old). Outcome measures included pregnancy, delivery and neonatal complications. Read More

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February 2021

Temporal persistence of residual fetal cell-free DNA from a deceased cotwin after selective fetal reduction in dichorionic diamniotic twin pregnancies.

Prenat Diagn 2021 Jan 13. Epub 2021 Jan 13.

BGI-Shenzhen, Shenzhen, China.

Objectives: To determine the temporal persistence of the residual cell-free DNA (cfDNA) of the deceased cotwin in maternal circulation after selective fetal reduction and evaluate its long persistence in noninvasive prenatal testing (NIPT).

Methods: Dichorionic diamniotic twins (N = 5) undergoing selective fetal reduction because of a trisomy were recruited. After informed consent, maternal blood was collected immediately before reduction and periodically after reduction until birth. Read More

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January 2021

Clinical Significance of Velamentous Cord Insertion Prenatally Diagnosed in Twin Pregnancy.

J Clin Med 2021 Feb 3;10(4). Epub 2021 Feb 3.

Department of Obstetrics and Gynecology, University of Ulsan College of Medicine, Asan Medical Center, Seoul 05505, Korea.

Background: The purpose of this study was to evaluate the prevalence of velamentous cord insertion (VCI) and the actual association between pathologically confirmed VCI and perinatal outcomes in twins based on the chorionicity.

Methods: All twin pregnancies that received prenatal care at a specialty clinic for multiple pregnancies, from less than 12 weeks of gestation until delivery in a single institution between 2015 and 2018 were included in this retrospective cohort study.

Results: A total of 941 twins were included in the study. Read More

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February 2021

Simpson-Golabi-Behmel-Syndrome in Dichorionic-Diamniotic Twin Pregnancy.

Clin Pract 2021 Feb 2;11(1):75-80. Epub 2021 Feb 2.

Department of Obstetrics and Feto-maternal Medicine, Medical University of Vienna, 1090 Vienna, Austria.

Simpson-Golabi-Behmel syndrome (SGBS) is a rare x-linked overgrowth syndrome with distinct clinical features, which is difficult to diagnose prenatally. We report the diagnosis of SGBS in dichorionic-diamniotic twin pregnancies in the first trimester by ultrasound and genetic testing. The affected fetus developed polyhydramnios and the cervical length of the mother decreased significantly. Read More

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February 2021

Twin chorionicity-specific population birth-weight charts developed with adjustment for estimated fetal weight.

Ultrasound Obstet Gynecol 2021 Feb 4. Epub 2021 Feb 4.

Twins Trust Centre for Research and Clinical Excellence, St George's University Hospitals NHS Foundation Trust, Blackshaw Road, London, SW17 0RE, UK.

Objective: To construct chorionicity-specific birthweight reference charts for dichorionic diamniotic (DCDA) and monchorionic diamniotic (MCDA) twin pregnancies incorporating estimated fetal weight (EFW) data in order to adjust for the relationship between suboptimal growth and premature delivery. An additional aim of this study was to determine if the inclusion of complicated twin pregnancies impacts the reference charts produced.

Methods: The Inclusion criteria were twin pregnancy of known chorionicity, known pregnancy outcome, last ultrasound scan within 14 days of birth which took place between 25 and 38 weeks (Analysis A). Read More

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February 2021

Conjoined twins in a spontaneous monochorionic triplet pregnancy: A case report and literature review.

Medicine (Baltimore) 2021 Jan;100(4):e24490

Department of Ultrasound, West China Second University Hospital.

Rationale: Conjoined twins are a rare complication of monochorionic pregnancies and an extremely rare condition in spontaneous triplet pregnancies. We report a case of conjoined twins in a spontaneous monochorionic triplet pregnancy. The conjoined twins might have suffered from twin anemia-polycythemia sequence, which was reported to be extremely rare. Read More

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January 2021

Neonatal infection in twins: clinical spectrum and management dilemma.

BMJ Case Rep 2021 Jan 27;14(1). Epub 2021 Jan 27.

Royal University Hospital, Saskatoon, Saskatchewan, Canada.

The clinical manifestation of could vary from asymptomatic bacteraemia to systemic bloodstream infection and meningitis. We describe an unusual course of infection in twins, emphasising commencement of appropriate antimicrobial therapy. A set of male dichorionic diamniotic twins were delivered at 34 weeks of gestation by caesarian section. Read More

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January 2021

Clinical Utility of Increased Nuchal Translucency at 11-13 Weeks of Gestation in Twin Pregnancies Based on the Chorionicity.

J Clin Med 2021 Jan 23;10(3). Epub 2021 Jan 23.

Department of Obstetrics and Gynecology, Asan Medical Center, University of Ulsan College of Medicine, Seoul 05505, Korea.

To assess clinical implications of increased nuchal translucency (INT) in twin pregnancies based on the chorionicity. This was a retrospective review of the twin pregnancies who underwent first trimester ultrasound with nuchal translucency (NT) measurement at 11-13 weeks of gestation from January 2006 to December 2014. Data were collected using the OB database and the chart review. Read More

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January 2021

Noninvasive prenatal screening in twin pregnancies with cell-free DNA using the IONA test: a prospective multicenter study.

Am J Obstet Gynecol 2021 Jan 15. Epub 2021 Jan 15.

Fetal Medicine Unit, Department of Obstetrics and Gynaecology, and Twins Trust Centre for Research and Clinical Excellence, St George's University Hospitals NHS Foundation Trust, London, United Kingdom; Nuffield Department of Women's and Reproductive Health, University of Oxford, John Radcliffe Hospital, Oxford, United Kingdom.

Background: In singleton pregnancies, studies investigating cell-free DNA in maternal blood have consistently reported high detection rate and low false-positive rate for the 3 common fetal trisomies (trisomies 21, 18, and 13). The potential advantages of noninvasive prenatal testing in twin pregnancies are even greater than in singletons, in particular lower need for invasive testing and consequent fetal loss rate. However, several organizations do not recommend cell-free DNA in twin pregnancies and call for larger prospective studies. Read More

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January 2021

Uterine Artery Doppler Reference Ranges in a Twin Caucasian Population Followed Longitudinally From 17 to 37 Weeks Gestation Compared to Singletons.

J Ultrasound Med 2021 Jan 13. Epub 2021 Jan 13.

Department of Reproductive Health, Centre of Postgraduate Medical Education, Warsaw, Poland.

Objectives: The primary aim was to measure uterine artery (UtA) indices in twin pregnancies of Polish Caucasian women and compare it with a previously published study by Geipel et al for DC twins (2011). The secondary aim was to find differences in UtA indices in MC, DC twins, and singletons.

Methods: A prospective longitudinal evaluation of UtA Doppler indices in 1462 examinations of twins and 5766 examinations of singletons between 17 and 37 gestational age (GA). Read More

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January 2021

Dichorionic twin pregnancy with sirenomelia and chromosomal anomaly in 1 fetus: A case report.

Medicine (Baltimore) 2021 Jan;100(1):e24229

Department of Obstetrics & Gynecology.

Rationale: Sirenomelia is a rare congenital malformation that threatens fetal survivals. The cases in which twin with sirenomelia and chromosomal abnormality have been seldomly reported. We reported a dichorionic twin case in which one twin had sirenomelia, the other twin had a normal phenotype, and they had different chromosomal abnormalities. Read More

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January 2021

Establishing the Most Accurate Due Date in Dichorionic Twin Gestations by First and Second Trimester Ultrasound.

J Ultrasound Med 2021 Jan 11. Epub 2021 Jan 11.

Department of Obstetrics and Gynecology, Naval Medical Center, Portsmouth, VA, USA.

Objective: To determine the optimal sonographic dating of dichorionic gestations.

Materials And Methods: We reviewed dichorionic pregnancies conceived with assisted reproductive technologies (ART) at 2 institutions between 2006-2016, excluding fetuses with major anomalies. Gestational age was calculated with smaller, larger, and mean of the crown-rump lengths (CRL) and biometry midgestation and compared to the ART age. Read More

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January 2021

Influence of indications on perinatal outcomes after radio frequency ablation in complicated monochorionic pregnancies: a retrospective cohort study.

BMC Pregnancy Childbirth 2021 Jan 9;21(1):41. Epub 2021 Jan 9.

Department of Obstetrics, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, China.

Background: Radiofrequency ablation (RFA) is recommended to prevent potential neurological injury or intrauterine foetal death (IUFD) of the co-twin(s) in complicated monochorionic (MC) pregnancies. However, the impacts of various indications on the pregnancy outcome following RFA remain unclear. This study aimed to determine how the indications influence the perinatal outcomes in complicated MC pregnancies undergoing radiofrequency ablation. Read More

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January 2021

Neutrophil-to-Lymphocyte Ratio and Platelet-to-Lymphocyte Ratio in Twins Compared with Singletons.

South Med J 2021 Jan;114(1):28-31

From the Department of Obstetrics and Gynecology, New York Health + Hospitals/Lincoln, Bronx, New York.

Objectives: It is well known that twin pregnancies confer a high degree of adverse perinatal outcomes. Fetal growth restriction, preterm labor/delivery, and hypertensive disorders of pregnancy are among the causal etiologies associated. Hematologic parameters, specifically, the neutrophil:lymphocyte ratio (NLR), the platelet:lymphocyte ratio (PLR), and some of the routine complete blood cell count components denote a peculiar inflammatory and immunologic profile and have been used as clinical markers for specific obstetric syndromes. Read More

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January 2021

Maternal hemodynamics, arterial stiffness and elastic aortic properties in twin pregnancy.

Physiol Meas 2021 01 1;41(12):125001. Epub 2021 Jan 1.

Department of Obstetrics and Gynecology, University of Brescia, Brescia, Italy. Equally contributors.

Objective: There is scant information about maternal cardiovascular hemodynamic change during twin pregnancies. Aim of the study is to investigate longitudinal changes in maternal arterial stiffness, elastic aortic properties and ventricular-arterial coupling (VAC) in uncomplicated twin pregnancies compared to singleton ones.

Approach: In this prospective longitudinal study, we performed applanation tonometry and transthoracic echocardiography in the first (T1; 10-15 weeks' gestation (w)), second (T2; 19-26 w) and third trimesters (T3; 30-38 w) in women with uncomplicated twin pregnancies, both monochorionic and dichorionic. Read More

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January 2021