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Higher order aberrations and retinal image quality during short-term accommodation in children.

Vision Res 2021 Jul 19;188:74-84. Epub 2021 Jul 19.

Queensland University of Technology, Contact Lens and Visual Optics Laboratory, School of Optometry and Vision Science, Centre for Vision and Eye Research, Brisbane, Queensland, Australia.

Changes in higher order aberrations (HOA's) and retinal image quality during accommodation have not previously been examined in children. This study measured ocular HOA's in ninety non-myopic, school-aged children during short-term accommodation tasks at 0, 3, 6, and 9 D demands presented via a Badal optometer mounted to a Hartmann-Shack wavefront aberrometer (COAS-HD, Wavefront Sciences). Eighty-four participants who exhibited active accommodation were included in the analyses. Read More

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Association of preoperative cone biopsy with recurrences after radical hysterectomy.

Arch Gynecol Obstet 2021 Jul 21. Epub 2021 Jul 21.

Department of Gynecology and Obstetrics, Hannover Medical School, Carl-Neuberg-Straße 1, 30625, Hanover, Germany.

Objective: To evaluate association of preoperative cone biopsy with the probability of recurrent disease after radical hysterectomy for cervical cancer.

Methods: This is a retrospective single-center study. Patients with cervical cancer stage IA1 with LVSI to IIA2 and squamous, adenosquamous and adenocarcinoma subtype were included. Read More

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Acta Ortop Bras 2021 May-Jun;29(3):153-158

Universidade de São Paulo, Faculty of Medicine, Hospital das Clínicas, Institute of Orthopedics and Traumatology, HC-FMUSP, São Paulo, SP, Brazil.

Objective: To evaluate and compare anatomical measurements of C7, T1 and T2 vertebrae in children from 3 to 12 years of age to provide useful epidemiological data for determining the safe anatomical margin for transpedicular and translaminar fixation with screws in this population.

Methods: This observational retrospective cross-sectional study evaluated 76 computed tomography scans obtained over 6 months, analyzing the following parameters: the angle of attack, length, thickness and diameter of the pedicle; and the angle of attack, length and thickness of the lamina.

Results: The lamina length and thickness, as well as pedicle length varied in size according to age. Read More

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Contrast enhanced ultrasound as a new tool to estimate the performance of midline catheters in the single patient.

J Vasc Access 2021 Jul 21:11297298211034629. Epub 2021 Jul 21.

Department of Biomedical and Clinical Sciences "Luigi Sacco," University of Milan, Luigi Sacco Hospital, Milan, Italy.

Background: Contrast enhanced ultrasound (CEUS) through MicroBubbles Time (MBT) (time from infusion of saline with addition of micro-bubbles of air to visualization of first bubbles in right atrium (RA), visualized by subxiphoid or apical echocardiography) is an alternative to Intracavitary ECG and chest X-ray in evaluation of tip location in central venous catheters.

Objective: To evaluate feasibility and variability of CEUS in peripheral catheters (Midline-MC) in a cohort of patients and in a subgroup where tip location was also performed through chest X-ray. Secondary outcomes were verifying the correlation between MBT and distance between tip of MC and RA (anthropometric and radiological measures), body mass index (BMI), vein diameter at point of insertion. Read More

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High anatomical accuracy of a novel high-resolution wide-band dielectric imaging system in cryoballoon-based ablation.

Pacing Clin Electrophysiol 2021 Jul 21. Epub 2021 Jul 21.

Universitäres Herz- und Gefäßzentrum Hamburg-Eppendorf, Department of Cardiology, Hamburg, Germany.

Purpose: Recently, a novel cardiac imaging system based on a wide-band dielectric technology (KODEX-EPD) was introduced to guide catheter ablation. The aim of the study was to evaluate this 3D wide-band dielectric imaging system (WDIS) during cryoballoon (CB)-based atrial fibrillation (AF) ablation focusing on accuracy of pulmonary vein (PV)-anatomy.

Methods: In consecutive patients with symptomatic AF, CB-based ablation was performed in conjunction with the 3D WDIS. Read More

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Clinical and histologic evaluation of a fractional radiofrequency treatment of wrinkles and skin texture with novel 1-mm long ultra-thin electrode pins.

Lasers Surg Med 2021 Jul 20. Epub 2021 Jul 20.

Lumenis, Yokneam, Israel.

Background: Fractional radiofrequency (RF) microneedling technologies have shown effectiveness in treating skin laxity and wrinkles. We report the first experience using a novel device with 1-mm long ultrathin electrodes that utilizes a smooth RF-assisted ablation mode.

Objective: To evaluate the safety and effectiveness of treatment with a fractional RF device using 1. Read More

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Comparison of two different biomaterials in the bone regeneration (15, 30 and 60 days) of critical defects in rats.

Acta Cir Bras 2021 19;36(6):e360605. Epub 2021 Jul 19.

Associate Professor. Department of Morphology and Pathology - Universidade Federal de São Carlos - Sao Carlos (SP), Brazil.

Purpose: To evaluate and compare two types of different scaffolds in critical bone defects in rats.

Methods: Seventy male Wistar rats (280 ± 20 grams) divided into three groups: control group (CG), untreated animals; biomaterial group 1 (BG1), animals that received the scaffold implanted hydroxyapatite (HA)/poly(lactic-co-glycolic) acid (PLGA); and biomaterial group 2 (BG2), animals that received the scaffolds HA/PLGA/Bleed. The critical bone defect was induced in the medial region of the skull calotte with the aid of an 8-mm-diameter trephine drill. Read More

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Palliative Endovascular Intervention in Infants with Tetralogy of Fallot: A Case Series.

Arq Bras Cardiol 2021 Jul 16. Epub 2021 Jul 16.

Universidade federal do Paraná (UFPR), Curitiba, PR - Brasil.

Background: Endovascular stent placement in the right ventricular outflow tract (RVOT) has been an alternative to Blalock-Taussig (BT) surgery in the treatment of Tetralogy of Fallot (TOF) in symptomatic infants with low birth weight and complex anatomy.

Objective: To evaluate endovascular stent placement in the RVOT as a primary treatment for infants with TOF who are not candidates for BT surgery, and evaluate medium-term outcomes until the stent is removed during corrective surgery.

Methods: Six infants with TOF were treated with RVOT stenting from October 2015 to April 2018. Read More

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The Analysis of Morphoradiological Parameters in Predicting Risk of Basilar Artery Tip Aneurysm Rupture: A Retrospective Cohort Study.

Int J Gen Med 2021 12;14:3335-3342. Epub 2021 Jul 12.

College of Medicine, Imam Abdulrahman Bin Faisal University, King Fahd Hospital of the University, Al-Khobar City, Eastern Province, Saudi Arabia.

Purpose: Basilar artery tip aneurysms can have fatal consequences and poor prognostic outcomes in case of rupture. We investigated the standard parameters used to evaluate aneurysmal morphology to predict aneurysm rupture.

Patients And Methods: We measured the differences between ruptured and unruptured basilar bifurcation aneurysms in terms of morphological features, including aneurysm size, size ratio, aneurysm height, perpendicular height, aneurysm width, bottleneck ratio, aspect ratio, and present daughter domes, using 3D angiography. Read More

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Comparison of the transoral endoscopic thyroidectomy vestibular approach and open thyroidectomy: A propensity score-matched analysis of surgical outcomes and safety in the treatment of papillary thyroid carcinoma.

Surgery 2021 Jul 17. Epub 2021 Jul 17.

Department of Thyroid Surgery, The Second Affiliated Hospital of Zhejiang University, School of Medicine, Zhejiang, China.

Background: The transoral endoscopic thyroidectomy vestibular approach has been demonstrated to have similar surgical outcomes as open thyroidectomy for selected papillary thyroid carcinomas. This study aimed to evaluate and compare the surgical outcomes and safety of the transoral endoscopic thyroidectomy vestibular approach with those of open thyroidectomy in the treatment of papillary thyroid carcinoma with a diameter between >1 cm and ≤3.5cm. Read More

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The novel hybrid polycarbonate polyurethane / polyester three-layered large-diameter artificial blood vessel.

J Biomater Appl 2021 Jul 20:8853282211033415. Epub 2021 Jul 20.

Department of Vascular, Fuwai Hospital, National Center for Cardiovascular Disease, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

Background: The most common materials of artificial blood vessels are polyethylene terephthalate and polytetrafluoroethylene. But polycarbonate polyurethane (PCU) is an ideal material for vascular prostheses because of their excellent characteristics. As far as we know, our artificial blood vessel is the first type of hybrid PCU/polyester three-layered large-diameter artificial blood vessel in the world. Read More

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Retinal vascular geometry detection as a biomarker in diabetes mellitus.

Eur J Ophthalmol 2021 Jul 20:11206721211033488. Epub 2021 Jul 20.

State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, People's Republic of China.

Objective: To compare the vessel geometry characteristics of color fundus photographs in normal control and diabetes mellitus (DM) patients and to find potential biomarkers for early diabetic retinopathy (DR) based on a neural network vessel segmentation system and automated vascular geometry parameter analysis software.

Methods: A total of 102 consecutive patients with type 2 DM (T2DM) and 132 healthy controls were recruited. All participants underwent general ophthalmic examinations, and retinal fundus photographs were taken with a digital fundus camera without mydriasis. Read More

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Effect of ovulation synchronization program and season on pregnancy to timed artificial insemination in suckled beef cows.

Theriogenology 2021 Jul 14;172:223-229. Epub 2021 Jul 14.

School of Agriculture and Food Science, University College Dublin, Belfield, Dublin, Ireland; AGRIC Teagasc Grange, Dunsany, Meath, Ireland. Electronic address:

This study was conducted to (i) evaluate the requirement for the administration of GnRH coincident with insertion of a progesterone-releasing intravaginal device (PRID) and (ii) the effect of supplementing with 400 IU eCG at PRID removal on pregnancy per AI (P/AI) in spring and autumn calving suckled beef cows, subjected to a 7-d CO-Synch + PRID timed artificial insemination (TAI) program. Suckled beef cows (n = 1408) on 62 commercial farms were enrolled and randomly assigned to either of three treatments: 1) cows received a PRID and 100 μg GnRH on Day -10, followed by 25 mg PGF at PRID removal (Day -3) and 100 μg GnRH 72 h later (Day 0) at TAI (Treatment 1; n: spring = 236, autumn = 248); 2) as Treatment 1, but without GnRH at PRID insertion on Day -10 (Treatment 2; n: spring = 232, autumn = 227); 3) as Treatment 1, but cows also received 400 IU eCG at PRID removal on Day -3 (Treatment 3; n: spring = 233, autumn = 232). At Day -10, ovaries were examined by ultrasonography to evaluate the presence or absence of a corpus luteum (CL) and follicle(s) ≥ 10 mm in diameter. Read More

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Evaluation of Retinal Structure in Pediatric Subjects with Vitamin D Deficiency.

Am J Ophthalmol 2021 Jul 17. Epub 2021 Jul 17.

Adıyaman University Education and Research Hospital, Department of Pediatrics, Adıyaman, Turkey.

Purpose: To quantitatively evaluate the retinal structural parameters of pediatric patients who were determined to be deficient in vitamin D.

Design: Prospective, cross-sectional study METHODS: Retinal structural parameters, including the peripapillary retinal nerve fiber layer (RNFL), central macula, retinal layer, and choroidal thicknesses, central retinal artery equivalent (CRAE), and central retinal vein equivalent (CRVE), in pediatric subjects with vitamin D deficiency (Group 1) and those without (Group 2) were compared.

Results: Group 1 comprised 70 individuals, while Group 2 comprised 80 individuals. Read More

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Effect of insulin treatment on pulsatility ratio and resistance index of the retinal artery in patients with type 2 diabetes.

PLoS One 2021 20;16(7):e0254980. Epub 2021 Jul 20.

Department of Ophthalmology, Asahikawa Medical University, Asahikawa, Japan.

This study aimed to evaluate whether long-term insulin treatment is associated with abnormalities in retinal circulation in type 2 diabetic patients. We evaluated 19 eyes of nondiabetic individuals and 68 eyes of type 2 diabetic patients. The eyes of diabetic patients were classified into two groups according to the presence or absence of long-term insulin therapy. Read More

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Pathological changes within two weeks following spinal cord injury in a canine model.

Eur Spine J 2021 Jul 20. Epub 2021 Jul 20.

Department of Otolaryngology-Head and Neck Surgery, Graduate School of Medicine, Kyoto University, Konoe-Cho, Yoshida, Sakyo-Ku, Kyoto, 606-8501, Japan.

Purposes: This study aimed to investigate the histopathological changes that occur within 2 weeks following spinal cord injury (SCI) in dogs.

Methods: Eight adult female Beagle dogs were included in this study, and SCI was induced using an epidural balloon catheter. Two dogs were killed at each of the following four time points: immediately after the procedure and 1 day, 1 week, and 2 weeks after the procedure. Read More

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Predictive value of pupillography on intraoperative floppy iris syndrome in preoperative period.

Int J Ophthalmol 2021 18;14(7):1018-1024. Epub 2021 Jul 18.

Department of Ophthalmology, Balikesir Ataturk State Hospital, Balikesir 10020, Turkey.

Aim: To present the frequency of intraoperative floppy iris syndrome (IFIS) in cataract patients who taking alpha 1-a receptor antagonist (ARA) drugs, and evaluate the predictive value of pupil diameter (PD) changes in IFIS patients.

Methods: Male cataract patients who are under treatment with alpha-1a-ARAs (alfuzosin, tamsulosin) intraoperatively were evaluated and were grouped as with/without IFIS. The preoperative PD values were compared with controls. Read More

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Comparison of IOL-Master 700 and IOL-Master 500 biometers in ocular biological parameters of adolescents.

Int J Ophthalmol 2021 18;14(7):1013-1017. Epub 2021 Jul 18.

Department of Ophthalmology, the First Affiliated Hospital of Medical College, Xi'an Jiaotong University, Xi'an 710061, Shaanxi Province, China.

Aim: To compare the differences and consistency of IOL-Master 700 biometers applying swept optical coherence tomography with the conventional IOL-Master 500 applying partial coherence interference in terms of the ocular biological parameters in adolescents with ametropia.

Methods: A total of 110 adolescents (110 eyes) with ametropia were collected, including 55 males and 55 females; age 10.69±2. Read More

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Long-term clinical outcome of dental implants: A retrospective clinical study with a minimum follow-up between 9.5 and 17.7 years.

J Biol Regul Homeost Agents 2021 Mar-Apr;35(2 Suppl. 1):37-51

University of Milano, Department of Biomedical, Surgical and Dental Sciences, Milan, Italy.

The aim of this retrospective case series was to evaluate the clinical and radiographic outcomes of the patients that underwent implant surgery in all indication classes, with a follow-up of at least 9 years. 121 healthy patients in need for oral rehabilitation with dental implants were included in this study. 196 implants (160 conical, 73 cylindric design implants) were inserted. Read More

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Age- and sex-related profiles for macro, macro/micro and microvascular reactivity indexes: Association between indexes and normative data from 2609 healthy subjects (3-85 years).

PLoS One 2021 19;16(7):e0254869. Epub 2021 Jul 19.

Departamento de Fisiología, Facultad de Medicina, Centro Universitario de Investigación, Innovación y Diagnóstico Arterial (CUiiDARTE), Universidad de la República, Montevideo, Uruguay.

Vascular reactivity (VR), defined as blood vessels' capability to actively modify the diameter and flow resistances can be non-invasively assessed analyzing vascular response to forearm occlusion. Several VR indexes can be quantified: (i) ´microvascular´, which consider variables that depend almost exclusively on changes in distal resistances, (ii)´ macrovascular´, that evaluate the changes in brachial artery (BA) diameter, adjusting for blood flow stimulus, and (iii) ´macro/micro´, whose values depend on the micro and macrovascular response without discriminating each one´s contribution. VR indexes could not be associated. Read More

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Is Increased Intracranial Pressure a Factor in Persistent Headache After Coronavirus Disease 2019?

J Nerv Ment Dis 2021 Jul 16. Epub 2021 Jul 16.

Departments of Neurology Radiology, Adiyaman University Faculty of Medicine, Adiyaman, Turkey.

Abstract: This study aimed to determine pain characteristics in patients with persistent headache after COVID-19 and to investigate the role of increased intracranial pressure (ICP) in the pathogenesis of this headache. This is a case-control study comparing the parameters and measurements indicating increased ICP based on magnetic resonance imaging between COVID-19-diagnosed patients with persistent headache and a control group. Optic nerve sheath diameter (ONSD) and eyeball transverse diameter (ETD) were performed on the left eye of each participant. Read More

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"Carbopol-olive oil-based bigel drug delivery system of doxycycline hyclate for the treatment of acne".

Drug Dev Ind Pharm 2021 Jul 19:1-28. Epub 2021 Jul 19.

Department of Pharmaceutical Sciences, Dr. Harisingh Gour University, Sagar-470003, (MP), India.

Objective: The objective of this study was to prepare and evaluate the doxycycline hyclate containing bigel for the effective treatment of acne.

Method: Bigels are biphasic systems formed by water-based hydrogels and oil-based organogel. Carbopol 940 was used to prepare the hydrogel phase, whereas span-60 and olive oil for the oleogel phase. Read More

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Laparoscopic ultrasonography-guided cryoablation of locally advanced pancreatic cancer: a preliminary report.

Jpn J Radiol 2021 Jul 19. Epub 2021 Jul 19.

Pancreas Center, The Second Affiliated Hospital of Nanjing Medical University, Nanjing, 210003, People's Republic of China.

Objective: To evaluate safety and feasibility of laparoscopic ultrasonography (LUS)-guided cryoablation of locally advanced pancreatic cancer (LAPC).

Patients And Methods: From April 2018 to December 2018, ten patients (five women, five men; mean age 58.2 ± 9. Read More

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Impact of Microfluidization on the Emulsifying Properties of Zein-Based Emulsions: Influence of Diutan Gum Concentration.

Materials (Basel) 2021 Jul 1;14(13). Epub 2021 Jul 1.

Departamento de Ingeniería Química, Facultad de Química, Universidad de Sevilla, c/Profesor García González, 1, E41012 Sevilla, Spain.

Microfluidization is a preparation method that can be used to obtain emulsions with submicron droplet sizes. The first objective of this study was to evaluate the influence of homogenization pressure and cycles on droplet sizes using response surface methodology. Secondly, the influence of the diutan gum concentration incorporated in the optimized emulsion on rheological properties, microstructure, and physical stability was investigated. Read More

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Potential candidates for en bloc resection among patients with primary and recurrent bladder tumours.

Scand J Urol 2021 Jul 19:1-6. Epub 2021 Jul 19.

Department of Urology, Aarhus University Hospital, Aarhus, Denmark.

Introduction: Transurethral resection (TURB) is the gold standard treatment for non-muscle invasive bladder cancer (NMIBC). However, conventional TURB is possibly part of the mechanism leading to the high recurrence rate in NMIBC and the need for repeated procedures, as the method with piecemeal resection of the tumour violates basic oncological principles and compromises pathological examination. En bloc resection (EBR) could potentially overcome these flaws by improving pathological quality and thereby reducing the need for re-resections and could potentially also lower the risk of tumour seeding leading to early recurrences. Read More

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The use of pumice amended with sand media for domestic wastewater treatment in vertical flow constructed wetlands planted with lemongrass ().

Heliyon 2021 Jul 29;7(7):e07423. Epub 2021 Jun 29.

Department of Chemistry, Faculty of Science and Engineering, Nusa Cendana University, Kupang, Jalan Adisucipto Penfui Kupang, Indonesia.

The performance efficiency in constructed wetlands (CWs) technology is primarily affected by the media material and the types of plants used. Recently, investigations into the usage of local materials and plants in CWs has increased. Pumice is a material which is potential used as a media. Read More

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In vivo anticancer effects of Momordica charantia seed fat on hepatocellular carcinoma in a rat model.

J Ayurveda Integr Med 2021 Jul 15. Epub 2021 Jul 15.

Department of Veterinary Pathobiology, Faculty of Veterinary Medicine and Animal Science, University of Peradeniya, Peradeniya, Sri Lanka. Electronic address:

Background: Momordica charantia or bitter melon is a well-known vegetable with a number of therapeutic actions in Ayurvedic medicine. Alpha-eleostearic acid, a conjugated trienoic fatty acid present in bitter melon is proven to have anticancer properties. Crude seed oil from local bitter melon varieties could be an effective and economical anticancer therapy. Read More

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Free-breathing non-contrast flow-independent cardiovascular magnetic resonance angiography using cardiac gated, magnetization-prepared 3D Dixon method: assessment of thoracic vasculature in congenital heart disease.

J Cardiovasc Magn Reson 2021 Jul 19;23(1):91. Epub 2021 Jul 19.

Department of Diagnostic and Interventional Radiology, University Hospital Bonn, Venusberg-Campus 1, 53127, Bonn, Germany.

Background: To evaluate a non-contrast respiratory- and electrocardiogram-gated 3D cardiovascular magnetic resonance angiography (CMRA) based on magnetization-prepared Dixon method (relaxation-enhanced angiography without contrast and triggering, REACT) for the assessment of the thoracic vasculature in congenital heart disease (CHD) patients.

Methods: 70 patients with CHD (mean 28 years, range: 10-65 years) were retrospectively identified in this single-center study. REACT-CMRA was applied with respiratory- and cardiac-gating. Read More

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[Value of ATP synthase C subunit in predicting cardiac function and outcomes of sepsis].

Zhonghua Yi Xue Za Zhi 2021 Jul;101(27):2140-2146

Emergency Department, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, China.

To investigate the value of serum mitochondrial ATP synthase C subunit level in the evaluation of cardiac functional status and prognosis in patients with sepsis. A total of 165 sepsis patients admitted to the Emergency Intensive Care Unit (EICU) of the First Affiliated Hospital of Wenzhou Medical University from January 1, 2017 to December 31, 2018 were included, there were 103 males (62.4%) and 62 females (37. Read More

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Progesterone release profile and follicular development in Holstein cows receiving intravaginal progesterone devices.

Theriogenology 2021 Jul 7;172:207-215. Epub 2021 Jul 7.

Department of Animal Science, Luiz de Queiroz College of Agriculture (ESALQ), University of São Paulo, Piracicaba, SP, 13418-900, Brazil. Electronic address:

The aim of this study was to evaluate the progesterone (P4) release profile provided by eight commercial intravaginal P4 devices, as well as the effect of circulating P4 concentrations produced exclusively by these devices on the development of the dominant follicle (DF) in non-lactating multiparous Holstein cows. All cows were submitted to the same experimental design starting with the insertion of a reused P4 device (2 g - original P4 load) for 7 d, followed by two treatments of cloprostenol sodium (PGF; 0.482 mg), 24 h apart, 6 and 7 d after device insertion. Read More

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