4,044,815 results match your criteria diagnosis procedure


How important is the Sphenoseptal cell in identifying the skull base? Recent incidence and demonstration of endoscopic surgical steps.

Turk J Med Sci 2021 Apr 17. Epub 2021 Apr 17.

Background/aim: Because of close relations to important anatomical structures such as cavernous sinus and optic nerve, sphenoid sinus variations must be well trained by the Otolaryngologist who has an interest in endoscopic sinus surgery. Newly defined sphenoseptal cell (SSC) is one of those variations that may lead to insufficient endoscopic sinus surgery outcomes if not defined preoperatively with imaging studies. The present study aimed to present the main characteristics of this special type of nasal cell. Read More

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Association between active pulmonary tuberculosis and circulating microRNAs: A preliminary study from Turkey.

Turk J Med Sci 2021 Apr 17. Epub 2021 Apr 17.

Background/aim: Tuberculosis is a public health problem that still remains significant. For prevention, diagnosis and treatment on tuberculosis more effective novel biomarkers are needed. MicroRNAs can regulate innate and adaptive immune responses, alter host-pathogen interactions and affect progression of diseases. Read More

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Individual calculation of perfusion activity based on ventilation efficiency for V/P-SPECT.

Nuklearmedizin 2021 Apr 16. Epub 2021 Apr 16.

Klinik für Radiologie und Neuroradiologie - Abteilung für Nuklearmedizin, Klinikum Dortmund gGmbH, Dortmund, Germany.

Aim:  Implementation of the individual calculation of perfusion activity to ensure the guideline-compliant ratio of perfusion to ventilation (P/V-ratio) of ≥ 3 in the diagnosis of acute pulmonary embolism (PE) using V/P-SPECT.

Material And Methods:  50 consecutive V/P-SPECT examinations, in which a standard activity of 160 MBq was applied for perfusion imaging, are evaluated retrospectively. Based on this patient group an activity factor is determined, which provides a correlation between the applied perfusion activity and the expected perfusion counts of the gamma camera. Read More

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[Awareness and Use of Digital Health Services in Germany: A Cross-sectional Study Representative of the Population].

Gesundheitswesen 2021 Apr 16. Epub 2021 Apr 16.

Medizinische Fakultät, Institut für Arbeits-, Sozial- und Umweltmedizin, Heinrich-Heine-Universität Düsseldorf, Düsseldorf, Deutschland.

Objectives: In light of the current efforts of health policy to implement eHealth, the question arises which sections of the population already use online self-help in order to tailor them to users' needs. The present study aims to determine the differences in the use of health information and psychological online counseling based on socio-demographic variables, health status and previous illnesses.

Methods: The basis for the cross-sectional data analyses using logistic regression analysis was the innovation sample of the German socio-economic panel. Read More

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Metastases of Urothelium Carcinoma: Differential Diagnosis, Resection, and Survival.

Thorac Cardiovasc Surg 2021 Apr 16. Epub 2021 Apr 16.

Department of Thoracic Surgery, Agaplesion Markus Krankenhaus, Wilhelm-Epstein-Str. 4, Frankfurt am Main, Germany.

Background:  Due to its very aggressive nature and low survival chances, the metastasized urothelium carcinoma poses a challenge in regard to therapy. The gold-standard chemotherapy is platinum based. The therapy options are considered controversial, including new systemic therapies. Read More

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Flow-diverter stents in the early management of acutely ruptured brain aneurysms: effective rebleeding protection with low thromboembolic complications.

J Neurosurg 2021 Apr 16:1-8. Epub 2021 Apr 16.

4Neurology, Hadassah-Hebrew University Medical Center, Jerusalem, Israel; and.

Objective: Flow-diverter stents (FDSs) are not generally used for the management of acutely ruptured aneurysms with associated subarachnoid hemorrhage (SAH). Herein, the authors present their experience with FDSs in this scenario, focusing on the antiplatelet regimen, perioperative management, and outcome.

Methods: The authors retrospectively reviewed their institutional database for the treatment and outcomes of all patients with acutely ruptured aneurysms and associated SAH from July 2010 to September 2018 who had received an FDS implant as stand-alone treatment within 4 days after diagnosis. Read More

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Potential clinical value of circular RNAs as peripheral biomarkers for the diagnosis and treatment of major depressive disorder.

EBioMedicine 2021 Apr 13;66:103337. Epub 2021 Apr 13.

Department of Neurology, Affiliated ZhongDa Hospital, School of Medicine, Institution of Neuropsychiatry, Southeast University, Nanjing, Jiangsu 210009, China; Department of Psychology, Xinxiang Medical University, Xinxiang, Henan 453003, China; School of Life Science and Technology, Key Laboratory of Developmental Genes and Human Disease, Southeast University, Nanjing, Jiangsu 210096, China; Mental Health Center Zhejiang University School of Medicine, Hangzhou, Zhejiang 310013, China; Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen, Guangdong 518055, China. Electronic address:

Background: circular RNAs (circRNAs) are expressed abundantly in the brain and are implicated in the pathophysiology of neuropsychiatric disease. However, the potential clinical value of circRNAs in major depressive disorder (MDD) remains unclear.

Methods: RNA sequencing was conducted in whole-blood samples in a discovery set (7 highly homogeneous MDD patients and 7 matched healthy controls [HCs]). Read More

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The effect of platelet-rich fibrin (PRF) on wound healing, adhesion, and hemostasis after endoscopic sinus surgery in patients with nasal polyposis.

Am J Otolaryngol 2021 Mar 29;42(5):103010. Epub 2021 Mar 29.

Prof. Dr. Cemil Tascioglu City Hospital, Otorhinolaryngology Department, Turkey.

Purpose: Chronic rhinosinusitis (CRS) is one of the most common chronic diseases seen worldwide. Endoscopic sinus surgery (ESS) has become a widely accepted procedure for medically refractory chronic rhinosinusitis and nasal polyps. Prevention of revision surgery often depends on good wound healing and less adhesion formation. Read More

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Cystic cervical lymph nodes of papillary thyroid carcinoma, tuberculosis and human papillomavirus positive oropharyngeal squamous cell carcinoma: utility of deep learning in their differentiation on CT.

Am J Otolaryngol 2021 Apr 9;42(5):103026. Epub 2021 Apr 9.

Departments of Radiology, Boston Medical Center, Boston University School of Medicine, One Boston Medical Center Place, Boston, MA 02118, United States; Department of Otolaryngology-Head and Neck Surgery, Boston Medical Center, Boston University School of Medicine, One Boston Medical Center Place, Boston, MA 02118, United States; Department of Radiation Oncology, Boston Medical Center, Boston University School of Medicine, One Boston Medical Center Place, Boston, MA 02118, United States. Electronic address:

Objectives: Cervical lymph nodes with internal cystic changes are seen with several pathologies, including papillary thyroid carcinoma (PTC), tuberculosis (TB), and HPV-positive oropharyngeal squamous cell carcinoma (HPV+OPSCC). Differentiating these lymph nodes is difficult in the absence of a known primary tumor or reliable medical history. In this study, we assessed the utility of deep learning in differentiating the pathologic lymph nodes of PTC, TB, and HPV+OPSCC on CT. Read More

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Neurological disorders encountered in a pediatric emergency department.

Eur J Paediatr Neurol 2021 Apr 5;32:86-92. Epub 2021 Apr 5.

Pediatric Emergency Department, Assistance Publique des Hôpitaux de Paris, Robert Debré Hospital, Boulevard Serrurier, 75019, Paris, France. Electronic address:

Aim: Neurological disorders are one of the reasons for admission in pediatric emergency departments (PEDs). We aimed to evaluate the frequency of neurological disorders seen in a large tertiary PED.

Methods: We conducted a one-year retrospective study that included 1471 medical records. Read More

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Retinex model based stain normalization technique for whole slide image analysis.

Comput Med Imaging Graph 2021 Mar 17;90:101901. Epub 2021 Mar 17.

Physiological Signal Analysis Group, Center for Machine Vision and Signal Analysis, University of Oulu, Finland; Faculty of Information Technology and Electrical Engineering, University of Oulu, Finland.

Medical imaging provides the means for diagnosing many of the medical phenomena currently studied in clinical medicine and pathology. The variations of color and intensity in stained histological slides affect the quantitative analysis of the histopathological images. Moreover, stain normalization utilizing color for the classification of pixels into different stain components is challenging. Read More

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A Quality Improvement Initiative to Improve ADHD Follow-up rates Using School-based Telemedicine.

Acad Pediatr 2021 Apr 13. Epub 2021 Apr 13.

Department of Pediatrics, Golisano Children's Hospital, University of Rochester School of Medicine and Dentistry, Rochester, NY.

Objective: Patients with a new diagnosis of attention-deficit/hyperactivity disorder (ADHD) who are prescribed stimulant medication need regular follow-up. Guidelines recommend follow-up within 30 days of stimulant initiation or change but this goal is seldom achieved. This quality improvement (QI) study in an urban academic outpatient practice aimed to: 1) assess whether use of school-based telemedicine increases rates of follow-up within 30 days and decreases the number of days to follow-up for ADHD, and 2) compare rates of 30-day follow-up via in-person vs telemedicine visits. Read More

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Surgical management of diaphragmatic and thoracic endometriosis': a French multicentric descriptive study.

J Gynecol Obstet Hum Reprod 2021 Apr 13:102147. Epub 2021 Apr 13.

Department of gynecology, Croix Rousse University Hospital, Hospices civils de Lyon (HCL), 103 Grande Rue de la Croix-Rousse, 69004 Lyon, France. Electronic address:

Introduction: Surgical management of Diaphragmatic and thoracic endometriosis (DTE) is still controversial, a thoracic or an abdominal approach can be proposed.

Methods: We conducted a multicentric retrospective study in 8 thoracic, gynecology or digestive surgery units in 5 French university hospitals. The main objective was to review the current management of DTE. Read More

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Imported scrub typhus in Europe: report of three cases and a literature review.

Travel Med Infect Dis 2021 Apr 13:102062. Epub 2021 Apr 13.

Department of Infectious/Tropical Diseases and Microbiology (DITM), IRCCS Sacro Cuore Don Calabria Hospital, Negrar, Verona, Italy. Electronic address:

Background: Scrub typhus is a vector-borne rickettsial infection, which can cause relevant morbidity and mortality. While the number of cases is around a million per year globally, the infection is seldom diagnosed in travellers from Europe.

Methods: We herein report three cases diagnosed in Italian travellers and review the literature about imported cases in Europe in the last 60 years. Read More

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Review of Temporal Reasoning in the Clinical Domain for Timeline Extraction: Where we are and where we need to be.

J Biomed Inform 2021 Apr 13:103784. Epub 2021 Apr 13.

Virginia Commonwealth University, 401 S. Main St., Richmond, VA 23284, USA.

Understanding a patient's medical history, such as how long symptoms last or when a procedure was performed, is vital to diagnosing problems and providing good care. Frequently, important information regarding a patient's medical timeline is buried in their Electronic Health Record (EHR) in the form of unstructured clinical notes. This results in care providers spending time reading notes in a patient's record in order to become familiar with their condition prior to developing a diagnosis or treatment plan. Read More

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Diagnostic accuracy of LAMP versus PCR over the course of SARS-CoV-2 infection.

Int J Infect Dis 2021 Apr 13. Epub 2021 Apr 13.

Department of Infectious Diseases, Fujita Health University School of Medicine, Toyoake, Aichi, Japan; Division of Infectious Diseases, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.

Objective: Reverse transcription loop-mediated isothermal amplification (RT-LAMP) has been validated for diagnosis of several viral infections. However, its diagnostic accuracy in detecting SARS-CoV-2 in real-life clinical settings remains unclear. The aim of this study was to determine the diagnostic sensitivity and specificity of RT-LAMP compared to reverse transcription-quantitative polymerase chain reaction (RT-qPCR) over the disease course of COVID-19. Read More

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Diagnostic Serial Interval as an Indicator for Effectiveness of Contact Tracing in the COVID-19 Pandemic - A Simulation Study.

Int J Infect Dis 2021 Apr 13. Epub 2021 Apr 13.

Seminar for Statistics, Department of Mathematics, ETH Zurich, Rämistrasse 101, 8092 Zurich, Switzerland.

Background: While the role of contact tracing in the containment of the COVID-19 epidemic remains important until vaccines are widely available, literature on objectively measurable indicators for the effectiveness of contact tracing is scarce. We suggest the diagnostic serial interval, the time between the diagnosis of the infector and infectee, as a new indicator for the effectiveness of contact tracing.

Methods: Using an agent-based simulation model, we demonstrate how the diagnostic serial interval correlates with the course of the epidemic. Read More

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Additional drug resistance for Mycobacterium tuberculosis during turnaround time for drug-susceptibility testing in China, a multicenter observational cohort study.

Int J Infect Dis 2021 Apr 13. Epub 2021 Apr 13.

Department of Global Public Health, Karolinska Institute, Stockholm, Sweden.

Background: Although phenotypic drug susceptibility testing (DST) of Mycobacterium.Tuberculosis (Mtb) takes up to 6-8 weeks, little is known about how drug susceptibility is affected during this period.

Methods: We performed a prospective cohort study to investigate the development of drug resistance (DR) during turnaround time (TAT), including 359 pulmonary tuberculosis (PTB) patients with a baseline DST result of a Mtb isolate collected at TB diagnosis and a follow-up DST result of a Mtb isolate collected when baseline DST result was available between 2013 and 2018. Read More

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Response To Celiac Plexus Block Confirms Neurogenic Etiology of Median Arcuate Ligament Syndrome.

J Vasc Interv Radiol 2021 Apr 13. Epub 2021 Apr 13.

Purpose: To evaluate the response of Median Arcuate Ligament Syndrome (MALS) symptoms, including postprandial pain, nausea, and vomiting to celiac plexus block (CPB) and to correlate response with arterial anatomy.

Materials And Methods: In a single-institution, retrospective cohort of clinically diagnosed MALS patients, 96 patients (75 female, 21 male, mean age 27 years) underwent 103 CT-guided percutaneous CPB procedures. Imaging, procedural, and clinical reports were reviewed. Read More

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High prevalence of SARS-CoV-2 infection in patients scheduled for digestive endoscopy after the peak of the first wave of the pandemic.

Gastroenterol Hepatol 2021 Apr 13. Epub 2021 Apr 13.

Servicio Digestivo ICS-Intitut d'Assistència Sanitària. Hospital Santa Caterina, Salt, Girona, Spain.

Healthcare professionals in endoscopy units have a possible risk of SARS-CoV-2 infection by different routes: inhalation of airborne droplets, aerosols, conjunctival contact and faecal-oral transmission.

Objective: To describe the detection of SARS-CoV-2 in a series of patients scheduled for digestive endoscopy at the Hospital Santa Caterina. Salt. Read More

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Combined use of two cone-beam computed tomography scans in the assessment of vertical root fracture in teeth with intracanal material.

J Endod 2021 Apr 13. Epub 2021 Apr 13.

Division of Oral Radiology, Department of Oral Diagnosis, Piracicaba Dental School, University of Campinas, Piracicaba, São Paulo, Brazil.

Introduction: The purpose of this preliminary study was to evaluate the diagnostic accuracy of the combined use of two cone-beam computed tomography (CBCT) volumes obtained with the tooth of interest positioned at different orientations in the detection of vertical root fracture (VRF).

Methods: Thirty single-rooted teeth were divided into two main groups (n=15): control and with VRF. The teeth were individually placed in a phantom composed of a human skull and mandible, which was CBCT scanned in two spatial orientations: conventional (with the Frankfurt plane parallel to the floor) and angled acquisition (tilted 90 degrees backward). Read More

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Trends in performance of ERCP among patients with surgically unresectable pancreatic cancer: a SEER-Medicare database study.

Gastrointest Endosc 2021 Apr 13. Epub 2021 Apr 13.

Department of Health Policy, Vanderbilt University School of Medicine, Nashville, TN; Vanderbilt-Ingram Comprehensive Cancer Center, Nashville, TN.

Background And Aims: Patients with biliary obstruction caused by adenocarcinoma of the pancreas head may require bile duct decompression to treat symptomatic cholestasis and/or permit systemic chemotherapy. Endoscopic retrograde cholangiopancreatography (ERCP) with biliary stent placement is the preferred intervention in such cases. The primary aim of this study was to determine what proportion of patients with surgically unresectable pancreatic adenocarcinoma undergo ERCP and whether this proportion has changed over time. Read More

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Diagnosis and Evaluation of Hypersensitivity Pneumonitis: CHEST Guideline and Expert Panel Report.

Chest 2021 Apr 13. Epub 2021 Apr 13.

American College of Chest Physicians, Glenview, IL, USA.

Background: The purpose of this analysis is to provide evidence-based and consensus-derived guidance for clinicians to improve individual diagnostic decision-making for hypersensitivity pneumonitis (HP) and decrease diagnostic practice variability.

Methods: Approved panelists developed key questions regarding the diagnosis of HP using the PICO (population, intervention, comparator, and outcome) format. MEDLINE (via PubMed) and the Cochrane Library were systematically searched for relevant literature, which was supplemented by manual searches. Read More

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The clinical role of combined serum C1q And hsCRP in predicting coronary artery disease.

Clin Biochem 2021 Apr 13. Epub 2021 Apr 13.

Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing 100029, China. Electronic address:

Objective: C1q has been shown to be associated with coronary heart disease (CAD) and can co-deposit with C-reactive protein (CRP) in atherosclerotic plaques. However, few studies have been conducted between C1q, CRP parameters and CAD. The aim of this study is to explore the relationship between C1q and CRP parameters and assess their clinical significance in CAD. Read More

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Acute leg compartment syndrome after CT-guided core needle biopsy of a giant cell tumor of the proximal fibula.

Acta Orthop Belg 2020 Dec;86(4):624-627

Imaging-guided percutaneous core needle biopsy (CNB) is the preferred diagnostic method for bone and soft tissue tumors. In less than 1% of cases, complications are clinically significant and include mainly haema-toma and bleeding. We present a case of acute compartment syndrome (ACS) following CNB of the proximal fibula. Read More

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December 2020

[Acute perforated appendicitis with pre-surgical diagnosis and bilateral inguinal hernia in preterm infants].

Rev Chil Pediatr 2020 Dec 21;91(6):936-940. Epub 2020 Oct 21.

Clínica Las Condes, Santiago, Chile.

Introduction: Acute neonatal appendicitis is a rare pathology, with few reports in the last 30 years. Since its clinical presentation and imaging studies are non-specific, most cases are diagnosed during a surgical pro cedure.

Objective: To describe a neonatal case of acute perforated appendicitis associated with later appearance of inguinal hernia, with pre-surgical diagnosis and treated through laparoscopy. Read More

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December 2020

Impact of smoke-free ordinance strength on smoking prevalence and lung cancer incidence.

PLoS One 2021 16;16(4):e0250285. Epub 2021 Apr 16.

Department of Surgery, Indiana University School of Medicine, Indianapolis, IN, United States of America.

Background: Smoke-free ordinances (SFO) have been shown to be effective public health interventions, but there is limited data on the impact SFO on lung cancer outcomes. We explored the effect of county-level SFO strength with smoking prevalence and lung cancer incidence in Indiana.

Methods: We obtained county-level lung cancer incidence from the Indiana State Cancer Registry and county-level characteristics from the Indiana Tobacco Prevention and Cessation Commission's policy database between 1995 and 2016. Read More

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A framework model using multifilter feature selection to enhance colon cancer classification.

PLoS One 2021 16;16(4):e0249094. Epub 2021 Apr 16.

School of Computing and Engineering, University of Huddersfield, Huddersfield, United Kingdom.

Gene expression profiles can be utilized in the diagnosis of critical diseases such as cancer. The selection of biomarker genes from these profiles is significant and crucial for cancer detection. This paper presents a framework proposing a two-stage multifilter hybrid model of feature selection for colon cancer classification. Read More

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Control of scabies in a tribal community using mass screening and treatment with oral ivermectin -A cluster randomized controlled trial in Gadchiroli, India.

PLoS Negl Trop Dis 2021 Apr 16;15(4):e0009330. Epub 2021 Apr 16.

Society for Education Action and Research in Community Health (SEARCH), Gadchiroli, Maharashtra, India.

Background: Scabies is often endemic in tribal communities and difficult to control. We assessed the efficacy of a community-based intervention using mass screening and treatment with oral ivermectin in controlling scabies.

Methods/ Findings: In this cluster randomised controlled trial, 12 villages were randomly selected from a cluster of 42 tribal villages in Gadchiroli district. Read More

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'The medicine is not for sale': Practices of traditional healers in snakebite envenoming in Ghana.

PLoS Negl Trop Dis 2021 Apr 16;15(4):e0009298. Epub 2021 Apr 16.

University of Groningen, University Medical Center Groningen, Department of Internal Medicine/Infectious Diseases, Groningen, The Netherlands.

Background: Snakebite envenoming is a medical emergency which is common in many tropical lower- and middle-income countries. Traditional healers are frequently consulted as primary care-givers for snakebite victims in distress. Traditional healers therefore present a valuable source of information about how snakebite is perceived and handled at the community level, an understanding of which is critical to improve and extend snakebite-related healthcare. Read More

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