52,260 results match your criteria diagnosis laryngeal


Neuroendocrine carcinoma of the larynx with Lambert-Eaton myasthenic syndrome: a rare case report and literature review.

J Int Med Res 2021 May;49(5):3000605211014784

Unit of Otorhinolaryngology, University Luigi Vanvitelli, Napoli, Italy.

This current report describes a rare clinical case of neuroendocrine carcinoma (NEC) of the larynx with associated Lambert-Eaton myasthenic paraneoplastic syndrome (LEMS). A 68-year-old male patient presented with severe dysphonia and dysphagia. He underwent a total laryngectomy and the excised lesion was extremely large. Read More

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Laryngopharyngeal reflux management in clinical practice.

J Biol Regul Homeost Agents 2021 Jan-Feb;35(1 Suppl. 2):55-59

UOC di Otorinolaringoiatria, Dipartimento Scienze dell'Invecchiamento, Neurologiche, Ortopediche e della testa collo. Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma, Italy.

Laryngopharyngeal reflux (LPR) is an inflammatory reaction of the mucosa of the pharynx, larynx, and other associated upper respiratory organs, caused by a reflux of stomach contents outside the esophagus. LPR is considered a relatively new clinical entity with a vast number of clinical manifestations that are sometimes treated empirically and without a correct diagnosis. Alginate is a reasonable therapeutic option as a first-line or add-on option. Read More

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Clinicopathologic features and outcome of head and neck mucosal spindle cell squamous cell carcinoma.

Virchows Arch 2021 May 12. Epub 2021 May 12.

Department of Pathology, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY, 10065, USA.

Spindle cell squamous cell carcinoma (SpC-SCC) is rare, accounting for 0.4-4% of head and neck (HN) SCCs. Better understanding of HN SpC-SCC clinicopathologic characteristics, especially features that predict outcome, is needed. Read More

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Quantitative laryngoscopy with computer-aided diagnostic system for laryngeal lesions.

Sci Rep 2021 May 12;11(1):10147. Epub 2021 May 12.

Department of Otolaryngology-Head and Neck Surgery, Tri-Service General Hospital, National Defense Medical Center Taipei, No. 325, Sec. 2, Cheng-Gong Road, Neihu District, Taipei, 114, Taiwan, Republic of China.

Laryngoscopes are widely used in the clinical diagnosis of laryngeal lesions, but such diagnosis relies heavily on the physician's subjective experience. The purpose of this study was to develop a computer-aided diagnostic system for the detection of laryngeal lesions based on objective criteria. This study used the distinct features of the image contour to find the clearest image in the laryngoscopic video. Read More

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Supracricoid laryngectomy: the impact of senescence on swallowing safety.

Einstein (Sao Paulo) 2021 10;19:eAO5715. Epub 2021 May 10.

Instituto Nacional de Câncer José Alencar Gomes da Silva - INCA, Rio de Janeiro, RJ, Brazil.

Objective: To investigate the association between aging and the functional aspects of swallowing (laryngeal penetration and laryngotracheal aspiration) in individuals who underwent supracricoid laryngectomy in the late period and without complaints.

Methods: A total of 70 patients, 56 (80%) aged >60 years and 14 (20%) <60 years, under outpatient follow-up, after cancer treatment and with no complaints of swallowing, performed functional evaluation using the swallowing videofluoroscopy. Image classification was performed using the penetration-aspiration scale developed by Rosenbek. Read More

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Glottic Malignant Fibrous Histiocytoma: A Case Report and Literature Review.

Case Rep Oncol 2021 Jan-Apr;14(1):641-646. Epub 2021 Mar 31.

Hazm Mebaireek General Hospital (HMGH), Hamad Medical Corporation (HMC), Doha, Qatar.

Pleomorphic sarcoma of the larynx is a rare variant of laryngeal cancer. We present the case of a 59-year-old male patient who has been smoking for 40 years. He presented with signs and symptoms of an obstructive glottic mass. Read More

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[Cervical Abscess after Surgery for Subglottic Granuloma due to Suture Thread Used at Thyroplasty with Arytenoid Adduction].

Kyobu Geka 2021 Feb;74(2):116-119

Department of Thoracic Surgery, Eiju General Hospital, Tokyo, Japan.

A 83-year-old man underwent thyroplasty with arytenoid adduction for right recurrent laryngeal nerve palsy 1 year ago. He had been suffering from hemosputum and cough for last 2 months, and was referred to our hospital for medical examination. Laryngoscopy and neck computed tomography showed subglottic nodule. Read More

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February 2021

Recurrent Stroke and Fatal Ruptured Mycotic Aneurysm Caused by Invasive Infection.

WMJ 2021 Apr;120(1):82-84

SSM Health Saint Mary's Hospital, Madison, Wisconsin.

Introduction: species are ubiquitous fungi that may cause invasive infection, particularly in immunocompromised patients. Invasive aspergillosis most commonly affects the lungs but can also disseminate to the central nervous system (CNS). Manifestations of CNS aspergillosis include abscesses and, rarely, mycotic aneurysm leading to subarachnoid hemorrhage (SAH). Read More

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Subglottic and tracheal stenosis associated with coronavirus disease 2019.

J Laryngol Otol 2021 May 11:1-3. Epub 2021 May 11.

ENT - Head and Neck Department, Royal London Hospital, Barts NHS Healthcare Trust, London, UK.

Background: Coronavirus disease 2019 critical care patients endure prolonged periods of intubation. Late tracheostomy insertion, large endotracheal tubes and high cuff pressures increase their risk of subglottic and tracheal stenosis. This patient cohort also often appears to have co-morbidities associated with laryngotracheal stenosis, including high body mass index and laryngopharyngeal reflux. Read More

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Presentation of External Ear Rosai-Dorfman Disease With Laryngeal Involvement.

Ear Nose Throat J 2021 May 11:1455613211016704. Epub 2021 May 11.

Bobby R. Alford Department of Otolaryngology-Head and Neck Surgery, Baylor College of Medicine, Houston, TX, USA.

Rosai-Dorfman disease (RDD) is a rare benign systemic histiocytic proliferation characterized by massive lymph node enlargement and sometimes associated with extranodal involvement. Even though it is considered to be benign, death can occur depending on the extent and location. Our case highlights a primary extranodal site of the right pinna with extension through the Eustachian tube to the subglottis. Read More

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Complex bronchial ruptures in blunt thoracic trauma: management and outcome.

Indian J Thorac Cardiovasc Surg 2021 May 15;37(3):311-315. Epub 2020 Sep 15.

General Surgery Department, Amiri Hospital, Kuwait City, Kuwait.

Complex bronchial ruptures are rare. Primary surgical repair is the preferred procedure. The aim of this retrospective case series was to study the clinical presentation of these complex bronchial injuries and their management and outcomes. Read More

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Laryngeal lichen planus mimicking vocal fold dysplasia.

Auris Nasus Larynx 2021 May 5. Epub 2021 May 5.

Otolaryngology Unit, Head and Neck Surgery, ASST del Garda, Manerbio Hospital, Brescia, Italy.

Lichen planus (LP) is an immune-mediated chronic inflammatory disease affecting the skin and mucosal membranes, either alone or in combination. LP rarely occurs in the larynx, where it presents as leukoplakia. Additionally, due to its responsiveness to corticosteroid drugs, differential diagnosis from other causes of laryngeal leukoplakia is needed (e. Read More

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A complex fracture of the hyoid bone and the larynx after a bicycle accident - Case report and review of literature.

Int J Surg Case Rep 2021 Apr 27;82:105922. Epub 2021 Apr 27.

Department of Otorhinolaryngology, Head and Neck Surgery, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Germany.

Introduction And Importance: Reports about laryngeal trauma and fractures of the hyoid bone are rare in the literature. Most cases are forensic cases and the results of postmortem analysis. Traumatic larynx and hyoid bone fractures represent a rare but important differential diagnosis of the common symptom hoarseness. Read More

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Radiosensitizing effects of curcumin alone or combined with GLUT1 siRNA on laryngeal carcinoma cells through AMPK pathway-induced autophagy.

J Cell Mol Med 2021 May 6. Epub 2021 May 6.

State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang, China.

In this study, we investigated the ability of curcumin alone or in combination with GLUT1 siRNA to radiosensitize laryngeal carcinoma (LC) through the induction of autophagy. Protein levels in tumour tissues and LC cells were measured by immunohistochemistry and Western blotting. In vitro, cell proliferation, colony formation assays, cell death and autophagy were detected. Read More

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Perioperative dexmedetomidine reduces emergence agitation without increasing the oculocardiac reflex in children: A systematic review and meta-analysis.

Medicine (Baltimore) 2021 May;100(18):e25717

Department of Anesthesiology, The Second Hospital of Jilin University, Changchun, China.

Background: Intravenous dexmedetomidine (DEX) has been used to prevent emergence agitation (EA) in children. The aim of this meta-analysis was to evaluate whether DEX decreases EA incidence without augmenting oculocardiac reflex (OCR) in pediatric patients undergoing strabismus surgery.

Methods: We searched PubMed, EMBASE, Chinese National Knowledge Infrastructure (CNKI), Wan Fang, and the Cochrane Library to collect the randomized controlled trials (RCTs) investigating the effects of intraoperative DEX in children undergoing strabismus surgery from inception to October 2019. Read More

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Diagnosis of recurrent laryngeal nerve paralysis following esophagectomy by evaluating movement of the vocal cords and arytenoid cartilages using ultrasonography.

Esophagus 2021 May 5. Epub 2021 May 5.

Department of Gastroenterological Surgery, Nagoya City University Graduate School of Medical Sciences, Mizuho-cho, 1 Kawasumi, Mizuho-ku, Nagoya, Aichi, Japan.

Advancements in thoracoscopic surgery have provided us with a deeper anatomical understanding of recurrent laryngeal nerve paralysis (RLNP), which is likely to occur after lymph node dissection. Taking a novel approach to researching the diagnosis of RLNP, we evaluated movement of the vocal cords and arytenoid cartilages using ultrasonography in patients who underwent thoracoscopic esophagectomy. RLNP occurred in six of the 24 patient cohort. Read More

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Application of High Speed Digital Imaging (HSDI) technique in the diagnosis of dysphonia in patients with laryngopharyngeal reflux disease (LPR).

Otolaryngol Pol 2021 Feb;75(3):1-5

Department of Clinical Phonoaudiology and Speech Therapy, Medical University of Bialystok, Poland.

Introduction Gastroesophageal reflux disease (GERD) may cause extra-esophageal complications, including laryngopharyngeal reflux disease (LPR). It is caused by morphological changes in the laryngeal mucosa due to the regurgitation of gastric contents. Laryngopharyngeal reflux has a wide symptomatology. Read More

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February 2021

Prognostic value of the nodal yield in elective neck dissections in patients with head and neck carcinomas.

Eur Arch Otorhinolaryngol 2021 May 3. Epub 2021 May 3.

Servicio de Otorrinolaringología. Hospital de la Santa Creu i Sant Pau, Universitat Autònoma de Barcelona, Barcelona, Spain.

Purpose: The objective of this study is to assess the prognostic capacity of the nodal yield in elective neck dissections performed in patients with head and neck squamous cell carcinomas (HNSCC) without clinical or radiological evidence of regional involvement (cN0) at the time of diagnosis.

Methods: Retrospective study including 647 patients with HNSCC treated with an elective neck dissection.

Results: Patients with < 15 dissected nodes (n = 172, 26. Read More

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Review of recent treatment trends of laryngeal cancer in Poland: a population-based study.

BMJ Open 2021 Apr 30;11(4):e045308. Epub 2021 Apr 30.

Department of Otorhinolaryngology, Head and Neck Surgery, Medical University of Warsaw, Warszawa, Poland.

Objectives: To investigate the utilisation of different treatment modalities for patients with laryngeal cancer (LC) during last decade in Poland.

Setting: Retrospective population-based study.

Participants: Patients with LC treated between January 2009 and December 2018. Read More

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Clinical significance of tumor-stroma ratio in head and neck cancer: a systematic review and meta-analysis.

BMC Cancer 2021 Apr 30;21(1):480. Epub 2021 Apr 30.

Institute of Biomedicine, Pathology, University of Turku and Turku University Hospital, Turku, Finland.

Background: The clinical significance of tumor-stroma ratio (TSR) has been examined in many tumors. Here we systematically reviewed all studies that evaluated TSR in head and neck cancer.

Methods: Four databases (Scopus, Medline, PubMed and Web of Science) were searched using the term tumo(u)r-stroma ratio. Read More

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[Widespread of Scleroma. A rare clinical case].

Vestn Otorinolaringol 2021 ;86(2):93-98

Peoples' Friendship University of Russian, Moscow, Russia.

Scleroma is a chronic infectious disease characterized by developing inflammation nye granulomas, mainly of the upper respiratory tract, with subsequent scarring. The reasons for the development of scleroma remain unclear, but it is generally accepted that the gram-negative coccal bacterium Klebsiella rhinoscleromatis (pas-Volkovich's loch - Frisch) is the causative agent of this disease. Endemic in the spread of scleroma is considered There are tropical and temperate zones such as Africa, Asia, Eastern Europe, South America and Central America. Read More

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[A clinical observation of laryngeal ossifying fibromyxoid tumor].

Vestn Otorinolaringol 2021 ;86(2):82-84

Voronezh regional pathoanatomical bureau, Voronezh, Russia.

A rare observation of ossifying fibromyxoid tumor of the larynx in a 23-year-old young man is presented. Surgical intervention, performed in two stages, provided a positive result. With dynamic observation of this patient for three years, continued growth and tumor recurrence were not observed. Read More

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[Prospects for a passive acoustic research method in otorhinolaryngology].

Vestn Otorinolaringol 2021 ;86(2):66-72

L.I. Sverzhevskiy Research and Clinical Institute of Otorhinolaryngology of the Moscow Healthcare Department, Moscow, Russia.

The authors of the article reviewed acoustic research methods in otorhinolaryngology. All acoustic diagnostic methods are divided into active and passive. Active acoustic methods are based on the emission of acoustic vibrations, in some cases with the subsequent reception and processing of reflected vibrations. Read More

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[Chronic catarrhal laryngitis in singers].

Vestn Otorinolaringol 2021 ;86(2):33-37

L.I. Sverzhevskiy Research and Clinical Institute of Otorhinolaryngology of the Moscow Healthcare Department, Moscow, Russia.

The article deals with optimization of treatment policy for singers with chronic catarrhal laryngitis. The survey sample is 51 singers with chronic catarrhal laryngitis of the age from 29 to 54 and the length of time worked from 8 to 22 years. The following methods are used: anamnesis, microbiological investigation, voice evaluation according to Visual Analog Scale (VAS), microlaryngoscopy, videolaryngostroboscopy, voice acoustic analysis (MDVP Kay Pentax system), statistical processing of results. Read More

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Liquid Biopsies in Head and Neck Cancer: Current State and Future Challenges.

Cancers (Basel) 2021 Apr 14;13(8). Epub 2021 Apr 14.

Department of Otolaryngology-Head and Neck Surgery, University of California, Davis, CA 95817, USA.

Head and neck cancers are the seventh most frequent malignancy worldwide, consisting of a heterogeneous group of cancers that develop in the oral cavity, pharynx, and larynx, with head and neck squamous cell carcinoma (HNSCC) being the most common pathology. Due to limitations with screening and physical examination, HNSCC often presents in advanced disease states and is thus associated with poor survival. In this setting, liquid biopsies, or obtaining patient bodily fluid samples for cancer diagnosis and prognosis, may play a dramatic role in optimizing care for HNSCC patients. Read More

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Influence of Recurrent Laryngeal Nerve Transient Unilateral Palsy on Objective Voice Parameters and on Voice Handicap Index after Total Thyroidectomy (Including Thyroid Carcinoma).

Int J Environ Res Public Health 2021 Apr 18;18(8). Epub 2021 Apr 18.

Department of Otorhinolaryngology and Maxillofacial Surgery, Military University Hospital, 16902 Prague, Czech Republic.

Total thyroidectomy (TT) is one of the most common surgical endocrine surgeries. Voice impairment after TT can occur not only in patients with recurrent laryngeal nerve (RLN) transient paralysis, but also in cases of normal vocal cord mobility. To compare voice limits using a speech range profile (SRP) in patients before and 14 days after TT and to investigate the influence of the early results of voice quality after TT on the personal lives of patients. Read More

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Non-Traumatic Laryngeal Fractures: A Systematic Review.

Turk Arch Otorhinolaryngol 2021 Mar 26;59(1):65-75. Epub 2021 Mar 26.

Department of Otorhinolaryngology, Army Medical College, Rawalpindi, Pakistan.

Non-traumatic laryngeal fractures are an extremely uncommon presentation, and the diagnosis can be missed. Recognizing these fractures is important to appropriately direct management because most have a good prognosis and result in complete recovery. This article aimed to review the characteristics of all documented cases of non-traumatic fractures of the larynx. Read More

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IgG4-Related Laryngeal Disease as a Possible Cause of Idiopathic Subglottic Stenosis: A Case Report.

Iran J Otorhinolaryngol 2021 Mar;33(115):119-125

Department of Otorhinolaryngology & Head- Neck Surgery, University of Szeged; Tisza Lajos krt. 111., 6725, Szeged, Hungary.

Introduction: Immunoglobulin G4-related disease (IgG4-RD) is a systemic fibro-inflammatory disorder. Laryngotracheal manifestation is very rare; therefore, it is usually associated with complex diagnostic and therapeutic problems.

Case Report: Herein, we report the case of a 35-year-old woman with idiopathic subglottic stenosis (ISGS) treated with one-step laryngotracheal reconstruction surgery. Read More

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An Assessment of Management Strategies for Adult Patients with Foreign-Body Sensation in the Neck.

J Emerg Trauma Shock 2021 Jan-Mar;14(1):28-32. Epub 2021 Mar 23.

Department of Emergency Medicine, Southside Hospital, Bay Shore, New York, USA.

Objectives: Patients come to the emergency department (ED) for the evaluation of foreign-body sensation in the neck. Given the dearth of clinical studies for this complaint, these patients are treated subjectively by different providers. We aim to propose a treatment approach that results in the timely diagnosis and removal of foreign bodies by comparing the common radiologic studies used in the ED for this complaint, determining the utility of consults, and providing an approach that minimizes length of stay. Read More

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Morbidity and mortality of parathyroid surgery - a retrospective analysis.

Rozhl Chir 2021 ;100(3):126-132

Introduction: The incidence of parathyroid - glandula parathyreoideae (PTG) diseases has been increasing worldwide. Unlike benign tumours, the incidence of malignant PTG tumours is rather a rare diagnosis. The morbidity of parathyroid surgery is associated with surgical removal of one or more pathologically altered parathyroid glands, particularly parathyroid adenoma associated with primary hyperparathyroidism (HPPT), but also hyperplasia associated with secondary or tertiary HPPT, and last but not least, HPPT due to parathyroid cancer. Read More

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