373,414 results match your criteria diagnosed renal

Fibromuscular dysplasia: its various phenotypes in everyday practice in 2021.

Kardiol Pol 2021 Jun 24. Epub 2021 Jun 24.

Pole of Cardiovascular Research, Institut de Recherche Expérimentale et Clinique and Division of Cardiology, Cliniques Universitaires Saint-Luc, Université Catholique de Louvain, Brussels, Belgium.

Fibromuscular dysplasia (FMD) is a non-atherosclerotic vascular disease that may involve medium-sized muscular arteries throughout the body. The pathogenesis of FMD remains poorly understood, but a combination of genetic and environmental factors may be involved. The majority of FMD patients are women, but men may have a more progressive disease, especially when smoking. Read More

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Systemic pseudohypoaldosteronism-1 with episodic dyslipidemia in a Sudanese child.

Endocrinol Diabetes Metab Case Rep 2021 Jun 1;2021. Epub 2021 Jun 1.

Departmentof Pediatric Endocrinology, Faculty of Medicine, University of Khartoum, Khartoum, Sudan.

Summary: Systemic pseudohypoaldosteronism type 1 (PHA1) is a rare genetic syndrome of tissue unresponsiveness to aldosterone caused by mutations affecting the epithelial Na channel (ENaC). The classical presentation is life-threatening neonatal/infantile salt-losing crises that mimic congenital adrenal hyperplasia (CAH). Consistently, extra-renal manifestations, including respiratory symptoms that resemble cystic fibrosis, are well reported. Read More

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Effects of early vs delayed progression on clinical and economic outcomes in patients with metastatic renal cell carcinoma treated with tyrosine kinase inhibitors as first-line therapy: results from the IMPACT RCC claims data analysis.

J Manag Care Spec Pharm 2021 Jun 24:1-11. Epub 2021 Jun 24.

EMD Serono Inc., Rockland, MA, USA; an affiliate of Merck KGaA, Darmstadt, Germany.

A key therapeutic goal of metastatic renal cell carcinoma (mRCC) treatment is delayed disease progression. The degree to which early therapeutic success affects downstream outcomes is not well established. To assess the clinical and economic impact of early vs delayed disease progression in patients with mRCC treated with first-line (1L) tyrosine kinase inhibitors (TKIs) followed by second-line (2L) therapy in the US Veterans Health Administration (VHA) database. Read More

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Knowledge, Attitude, and Willingness Toward Kidney Donation Among Health Sciences Students at King Saud Bin Abdulaziz University.

Front Public Health 2021 7;9:667582. Epub 2021 Jun 7.

Effat College of Engineering, Effat University, Jeddah, Saudi Arabia.

End-stage renal disease, as one of the most serious and major health problems, does not have many treatment options available. One of the best treatment modalities used to cure this debilitating disease is kidney transplantation. However, with the continuous increase in number of patients diagnosed with it, there is not enough supply of the organ. Read More

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Bartonellosis in transplant recipients: A retrospective single center experience.

World J Transplant 2021 Jun;11(6):244-253

Section of Infectious Diseases, Department of Medicine, Yale University School of Medicine, New Haven, CT 06510, United States.

Background: Bartonellosis is a rare but challenging condition to diagnose with a spectrum of clinical presentations in the immunocompromised host.

Aim: To further characterize the presentation of () infections in solid organ and hematopoietic stem cell transplant recipients.

Methods: We conducted a single-center retrospective study of all testing for 5012 transplant recipients receiving care at a single institution between 2011 and 2018. Read More

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Primary Small Cell Carcinoma of the Bladder.

Cureus 2021 May 21;13(5):e15146. Epub 2021 May 21.

College of Osteopathic Medicine, University of New England, Biddeford, USA.

A 64-year-old Caucasian man with a 20 to 25-pack-year cigarette smoking history presented to his primary care provider with the chief complaint of gross hematuria after experiencing three to four months of urinary frequency and urgency. His workup consisted of laboratory blood work, a renal/bladder ultrasound (US), a CT scan without contrast, cystoscopy with biopsy (with an attempted transurethral resection of bladder tumor), and a PET scan. He was diagnosed with stage T4 small cell carcinoma of the bladder (SCCB) shortly after seeking medical care with metastases to the liver, bone, and lymph nodes. Read More

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Association between comorbid sleep apnoea-hypopnoea syndrome and prognosis of intensive care patients: a retrospective cohort study.

BMJ Open 2021 Jun 23;11(6):e048886. Epub 2021 Jun 23.

Otorhinolaryngology Head and Neck Surgery, The University of Hong Kong - Shenzhen Hospital, Shenzhen, Shenzhen, People's Republic of China.

Objective: In this study, we investigated the association between comorbid sleep apnoea-hypopnoea syndrome (SAHS) and the prognosis of patients in an intensive care unit (ICU) to determine whether this relationship varies between different disease subgroups.

Methods: We conducted a retrospective cohort study using publicly available information from the critical care database Medical Information Mart for Intensive Care III. Adults (≥18 years of age) who attended the ICU for the first time were enrolled. Read More

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Quality indicators for systemic lupus erythematosus based on the 2019 EULAR recommendations: development and initial validation in a cohort of 220 patients.

Ann Rheum Dis 2021 Jun 23. Epub 2021 Jun 23.

Rheumatology and Clinical Immunology, Medical School, National and Kapodistrian University of Athens, "Attikon" University Hospital of Athens, Athens, Greece

Background: Quality of care is receiving increased attention in systemic lupus erythematosus (SLE). We developed quality indicators (QIs) for SLE based on the 2019 update of European League Against Rheumatism recommendations.

Methods: A total of 44 candidate QIs corresponding to diagnosis, monitoring and treatment, were independently rated for validity and feasibility by 12 experts and analysed by a modified Research and Development Corporation/University of California Los Angeles model. Read More

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Acute urinary retention in pediatric cerebral palsy: Is there an optimal management strategy?

J Pediatr Urol 2021 Jun 5. Epub 2021 Jun 5.

Department of Urology, University of California San Diego, 200 West Arbor Drive MC 7897, San Diego, CA 92103, USA; Rady Children's Hospital - San Diego, 3020 Childrens Way MC 5120, San Diego, CA 92123, USA.

Introduction And Objective: Cerebral palsy (CP) patients commonly have lower urinary tract dysfunction. Urinary retention (UR), which has been associated with dysfunctional voiding in CP can correlate to chronic upper tract dysfunction. We sought to provide insight into the pediatric presentation of acute UR in patients with CP and subsequent outcomes in this at-risk population. Read More

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Postoperative outcomes of ureteroscopy for pediatric urolithiasis: A secondary analysis of the National Surgical Quality Improvement Program Pediatric.

J Pediatr Urol 2021 Jun 10. Epub 2021 Jun 10.

Division of Urology, Department of Surgery, Schulich School of Medicine & Dentistry, Western University, London, ON, Canada. Electronic address:

Introduction: Incidence of pediatric urinary stone disease (PUSD) has increased over recent decades. Innovations in ureteroscopic technology has expanded the role of endourologic stone management in children. However, there is currently no consensus on the optimal use of ureteroscopy (URS) within the heterogenous PUSD population. Read More

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Monogenic lupus due to DNASE1L3 deficiency in a pediatric patient with urticarial rash, hypocomplementemia, pulmonary hemorrhage, and immune-complex glomerulonephritis.

Eur J Med Genet 2021 Jun 20:104262. Epub 2021 Jun 20.

Department of Medical Genetics, Cukurova University Faculty of Medicine, Adana, Turkey. Electronic address:

Systemic lupus erythematosus (SLE) is a multisystem autoimmune disease and usually involves the skin, musculoskeletal system, and kidneys. More than 30 genes have been to monogenic lupus, so far. Monogenic lupus is often characterized by an early-onset, similar family history, and syndromic appearance. Read More

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Machine Learning-Enabled Renal Cell Carcinoma Status Prediction Using Multiplatform Urine-Based Metabolomics.

J Proteome Res 2021 Jun 23. Epub 2021 Jun 23.

Department of Biochemistry and Molecular Biology, Complex Carbohydrate Research Center, University of Georgia, Athens, Georgia 30602, United States.

Renal cell carcinoma (RCC) is diagnosed through expensive cross-sectional imaging, frequently followed by renal mass biopsy, which is not only invasive but also prone to sampling errors. Hence, there is a critical need for a noninvasive diagnostic assay. RCC exhibits altered cellular metabolism combined with the close proximity of the tumor(s) to the urine in the kidney, suggesting that urine metabolomic profiling is an excellent choice for assay development. Read More

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[Renal toxicity of antineoplasic agents].

Rev Prat 2021 Feb;71(2):193-197

"Service de néphrologie, dialyse et transplantation, hôpital Foch, Suresnes, France".

"Renal toxicity of antineoplasic agents Renal toxicity of antineoplasic agents is a common complication faced by oncologists and nephrologists whose incidence depends on therapeutic classes used and patient's comorbidities. Nephrotoxicity is variable, according to mecanisms, chronology and potential reversibility. Besides acute kidney injury and/or chronic kidney disease, clinical features include several urinary abnormalities (mainly proteinuria). Read More

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February 2021

Successful endoscopic submucosal dissection of early gastric cancer located on gastric varices after treatment with balloon-occluded retrograde transvenous obliteration.

Clin J Gastroenterol 2021 Jun 23. Epub 2021 Jun 23.

Department of Gastroenterology, Shizuoka General Hospital, 4-27-1, Kita-ando, Aoi-ku, Shizuoka, Shizuoka, 420-8527, Japan.

Gastric varices occur in patients with liver cirrhosis and cause major bleeding when they rupture. We report a case of an 80-year-old man with liver cirrhosis and chronic renal failure who was diagnosed with a gastric tumor located on gastric varices that had increased in size. The patient underwent balloon-occluded retrograde transvenous obliteration (BRTO) to control bleeding, and the gastric varices were eradicated. Read More

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Characteristics of patients with emergency attendance for severe hypoglycemia and hyperglycemia in a general hospital in Japan.

Medicine (Baltimore) 2021 Jun;100(25):e26505

Department of Cardiology and Diabetes, Oji General Hospital, Tomakomai.

Abstract: Despite advances in treatments for diabetes mellitus (DM), severe acute glycemic crises still occur. In this study, the characteristics of patients who were transported to an emergency department due to acute glycemic crises were investigated.We enrolled patients who were transported to our hospital by ambulance due to hypoglycemia or hyperglycemia during the period from January 2015 to December 2019. Read More

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Harefuah 2021 Jun;160(6):377-381

Child Health and Sports Center, Meir Medical Center.

Introduction: McArdle disease (Glycogen storage disease type V) is a myopathy caused by an inherited deficit of muscle glycogen phosphorylase (PYGM). Since glycogen is an important fuel for muscular activity, people with McArdle's disease experience exercise intolerance. Dynamic or static vigorous exercise may lead to rhabdomyolysis, myoglobinuria and renal failure. Read More

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Harefuah 2021 Jun;160(6):349-354

Pediatric Dermatology Unit, Schneider Children's Medical Center of Israel.

Background: Traditionally, most children diagnosed with Henoch-Schonlein Purpura (HSP) were hospitalized. This policy gradually changed towards selective hospitalization, yet there are still no criteria for admitting pediatric patients with HSP.

Objectives: To examine the clinical features and criteria for hospitalization of pediatric patients with HSP. Read More

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Prostate Cancer Detected by Choroidal Tumor and Complete Response to Hormonal Therapy: Case Report and Literature Review of 24 Patients With Choroidal Metastasis From Prostate Cancer.

J Investig Med High Impact Case Rep 2021 Jan-Dec;9:23247096211026471

Urology, Okayama University Hospital, Okayama City, Japan.

Metastatic choroidal tumors derived from prostate cancer are rare. In this study, we report a patient who manifested a choroidal tumor as the initial presenting sign of prostate cancer and review 23 patients with choroidal metastasis of prostate cancer in the literature to answer a clinical question how the choroidal metastases would respond to hormonal therapy. A 73-year-old man presented with a choroidal tumor in the right eye. Read More

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EXPRESS: A Rare Case of Persistent Hyperkalaemia.

Ann Clin Biochem 2021 Jun 23:45632211028614. Epub 2021 Jun 23.

University Hospital of Wales, Medical Biochemistry and Immunology, Cardiff, United Kingdom of Great Britain and Northern Ireland.

Hyperkalaemia is a common biochemical finding that can allude to pre-analytical or truly pathological causes. Here, we present a case of a 41-year-old female patient who has regularly presented with incidences of isolated hyperkalaemia since 2012, with otherwise normal renal function and no other associated symptoms. Investigations into the patientâs family history revealed similar biochemical findings in her brother and eldest son. Read More

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Bench thrombolysis and "autotransplantation" as a rescue treatment for venous thrombosis after living-donor kidney transplantation.

Pediatr Transplant 2021 Jun 22:e14074. Epub 2021 Jun 22.

Pediatric Surgery, Department of Women's and Children's Health, Padua University Hospital, Padua, Italy.

Background: Allograft venous thrombosis is a severe complication after kidney transplantation (KT). Early diagnosis and prompt treatment are crucial in preserving the survival of the allograft. In this study, we aimed to describe an emergent strategy for the management of acute allograft venous thrombosis. Read More

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Light Chain Deposition Disease Diagnosed Using Computed Tomography-Guided Kidney Biopsy.

Cureus 2021 May 18;13(5):e15102. Epub 2021 May 18.

Department of Radiology, Teine Keijinkai Medical Center, Sapporo, JPN.

Light chain deposition disease (LCDD) is characterized by the deposition of monoclonal immunoglobulin light chains in the kidney, which can cause end-stage kidney disease if not treated. While kidney biopsy is required for definitive diagnosis, choosing an appropriate biopsy method may be problematic when examining patients with atrophic kidneys. A 66-year-old Japanese man was referred to our institution with a three-month history of leg edema. Read More

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Renal Lymphoma Mimicking a Retroperitoneal Hematoma.

Cureus 2021 May 18;13(5):e15099. Epub 2021 May 18.

Radiology, Hospital Beatriz Ângelo, Loures, PRT.

We report the case of a 65-year-old female with an atypical presentation of renal lymphoma at computed tomography (CT), which was initially misinterpreted as a retroperitoneal hematoma. This case highlights the importance to keep a high level of suspicion in order to make a prompt diagnosis since treatment strategies differ significantly. Read More

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Co-occurrence of Behçet disease with Ig A vasculitis revealed by ophtalmic examination: A case report.

Ann Med Surg (Lond) 2021 Jun 28;66:102446. Epub 2021 May 28.

Ophthalmology Department, Farhat Hached Hospital, Sousse, Tunisia.

Introduction: Renal involvment of Behçet disease is not usual and Ig A vasculitis complicated by Behçet disease is extremely rare.

Case Presentation: We report a case of Henoch Scholein purpura and nephritis associated with Behçet disease revealed by ophthalmic examination.

Clinical Discussion: Recurrent oral ulcer is not a manifestation of Ig A vasculitis which doesn't affect large or middle sized arteries. Read More

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Nutcracker syndrome: A rare cause of chronic pelvic pain and left back pain.

Radiol Case Rep 2021 Aug 8;16(8):2025-2030. Epub 2021 Jun 8.

Department of Radiology, National Institute of Oncology, UHC Ibn Sina, Mohamed V University, Faculty of Medicine, 57 rue Napoli apartment 09 ocean, Rabat 10040, Morocco.

The Nutcracker Syndrome is a rare and often unrecognized cause of chronic pelvic pain and left back pain. These symptoms are due to the left renal vein compression between the aorta and the superior mesenteric artery (anterior nutcracker) or between the aorta and the spine (posterior nutcracker). The variety of clinical manifestations make the diagnosis difficult and commonly delayed. Read More

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Two Rare Entities in One Patient: Mucinous Tubular and Spindle Cell Carcinoma of the Kidney and Peritoneal Adenomyomas.

Radiol Case Rep 2021 Aug 8;16(8):1974-1979. Epub 2021 Jun 8.

Radiology Department, Fundação Champalimaud, Lisbon, Portugal.

Mucinous tubular and spindle cell carcinoma of the kidney is a rare subtype of renal cell carcinoma, that is believed to portend a favorable prognosis. Adenomyomas are benign tumors that typically arise from the myometrium. Extrauterine adenomyomas are extremely rare, with only a few cases reported in the literature. Read More

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A cohort study to investigate sex-specific differences in ANCA-associated glomerulonephritis outcomes.

Sci Rep 2021 Jun 22;11(1):13080. Epub 2021 Jun 22.

Trinity Health Kidney Centre, Trinity College Dublin, The University of Dublin, Dublin, Ireland.

Data surrounding sex-specific differences in ANCA-associated vasculitis glomerulonephritis (ANCA-GN) outcomes is sparse. We hypothesised that the previously observed increased risk of end-stage kidney disease (ESKD) in males is driven by sex-specific variation in immunosuppression dosing. Patients were recruited to the Irish Rare Kidney Disease Registry or followed by the Royal Free Hospital vasculitis team (2012-2020). Read More

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[Colonic Mass Secondary to Sevelamer-associated Rectal Ulcer].

Korean J Gastroenterol 2021 Jun;77(6):305-308

Department of Gastroenterology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.

The phosphorous balance is clinically important in increasing the long-term outcomes and preventing complications of end-stage renal disease. Sevelamer is a phosphate binder used widely to regulate hyperphosphatemia. On the other hand, gastrointestinal side effects increase with increasing sevelamer intake. Read More

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Proliferative glomerulonephritis with monoclonal immunoglobulin deposits associated with parvovirus B19.

BMJ Case Rep 2021 Jun 22;14(6). Epub 2021 Jun 22.

Department of Medicine, Jacobi Medical Center, Bronx, New York, USA

Proliferative glomerulonephritis with monoclonal immunoglobulin deposits (PGNMID) is included in the group of dysproteinaemias causing renal disease. Only a minority of cases are associated with a haematological malignancy. Two cases have been linked to acute parvovirus B19 infections. Read More

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Active Surveillance in Metastatic Renal Cell Carcinoma: Results From the Canadian Kidney Cancer Information System.

Clin Genitourin Cancer 2021 May 15. Epub 2021 May 15.

Division of Medical Oncology, The Ottawa Hospital Cancer Centre, University of Ottawa, Ottawa, ON, Canada.

Background: Active surveillance (AS) is a commonly used strategy in patients with slow-growing disease. We aimed to assess the outcomes and safety of AS in patients with metastatic renal cell carcinoma (mRCC).

Patients And Methods: We used the Canadian Kidney Cancer information system (CKCis) to identify patients with mRCC diagnosed between January 1, 2011, and December 31, 2016. Read More

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Untargeted serum metabolomics and tryptophan metabolism profiling in type 2 diabetic patients with diabetic glomerulopathy.

Ren Fail 2021 Dec;43(1):980-992

Department of Nephrology, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, P.R. China.

Diabetic glomerulopathy (DG) remains the prevalent microvascular complication and leading cause of shortened lifespan in type-2 diabetes mellitus (T2DM) despite improvement in hyperglycemia control. Considering the pivotal role of kidney in metabolism, using untargeted metabolomic techniques to globally delineate the serum metabolite profiles will help advance understanding pathogenetic underpinnings of renal biopsy-confirmed DG from the perspective of metabolism specifically. Fourteen pathologically diagnosed DG patients secondary to T2DM and 14 age- and gender-matched healthy controls (HCs) were recruited for study. Read More

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December 2021