30,870 results match your criteria diagnosed polyps

Two Types of Polyp Shape Observed in the Stomach of Patients with Peutz-Jeghers Syndrome.

Acta Med Okayama 2021 Aug;75(4):471-477

Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences.

The characteristics of gastric polyps in patients with Peutz-Jeghers (PJ) syndrome (PJS) have not been fully investigated. The objective of this study was to reveal the endoscopic and pathologic findings of gastric polyps in patients with PJS. We reviewed 11 patients with PJS treated at 6 institutions, and summarized the endo-scopic and pathologic features of their gastric polyps. Read More

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Focus U-Net: A novel dual attention-gated CNN for polyp segmentation during colonoscopy.

Comput Biol Med 2021 Sep 2;137:104815. Epub 2021 Sep 2.

Department of Radiology, University of Cambridge, Cambridge, CB2 0QQ, United Kingdom; Cancer Research UK Cambridge Centre, University of Cambridge, Cambridge, CB2 0RE, United Kingdom. Electronic address:

Background: Colonoscopy remains the gold-standard screening for colorectal cancer. However, significant miss rates for polyps have been reported, particularly when there are multiple small adenomas. This presents an opportunity to leverage computer-aided systems to support clinicians and reduce the number of polyps missed. Read More

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September 2021

Automatic Detection of Colorectal Polyps Using Transfer Learning.

Sensors (Basel) 2021 Aug 24;21(17). Epub 2021 Aug 24.

Department of Surgery, 3-rd Surgery Clinic, Iuliu Hatieganu University of Medicine and Pharmacy, 400349 Cluj-Napoca, Romania.

Colorectal cancer is the second leading cause of cancer death and ranks third worldwide in diagnosed malignant pathologies (1.36 million new cases annually). An increase in the diversity of treatment options as well as a rising population require novel diagnostic tools. Read More

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[Functional endoscopic sinus surgery in a patient with cystic fibrosis after lung transplantation].

Vestn Otorinolaringol 2021 ;86(4):73-78

First Pavlov State Medical University of Saint Petersburg, St. Petersburg, Russia.

Cystic fibrosis is genetic multisystem disorder with a predominant lesion of the respiratory tract. The duration and quality of life of these patients depends on the state of respiratory function. Progressive lung dysfunction is still the leading cause of mortality patients with cystic fibrosis. Read More

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September 2021

[Role of topical antibacterial therapy in patients with cystic fibrosis].

Vestn Otorinolaringol 2021 ;86(4):59-66

I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University), Moscow,Russia.

Cystic fibrosis (cystic fibrosis) is an important medical and social problem. The main clinical manifestations that determine the prognosis and outcome of this disease are changes in the respiratory and digestive systems. In recent years, there has been an understanding of the importance of assessing pathological changes in the nasal cavity and paranasal sinuses in patients with cystic fibrosis. Read More

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September 2021

Prediction of the severity of colorectal lesion by fecal hemoglobin concentration observed during previous test in the French screening program.

World J Gastroenterol 2021 Aug;27(31):5272-5287

Site Isère & Drôme-Ardèche, Centre Régional de Coordination des Dépistages des Cancers en Auvergne-Rhône-Alpes, Meylan 38240, France.

Background: The rate of positive tests using fecal immunochemical test (FIT) does not decrease with subsequent campaigns, but the positive predictive value of advanced neoplasia significantly decreases in subsequent campaign after a first negative test. A relationship between the fecal hemoglobin concentration (Fhb) and the opportunity to detect a colorectal cancer in subsequent campaign has been shown.

Aim: To predict the severity of colorectal lesions based on Fhb measured during previous colorectal cancer screening campaign. Read More

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Establishment and validation of a computer-assisted colonic polyp localization system based on deep learning.

World J Gastroenterol 2021 Aug;27(31):5232-5246

Department of Gastroenterology, Changhai Hospital, Second Military Medical University/Naval Medical University, Shanghai 200433, China.

Background: Artificial intelligence in colonoscopy is an emerging field, and its application may help colonoscopists improve inspection quality and reduce the rate of missed polyps and adenomas. Several deep learning-based computer-assisted detection (CADe) techniques were established from small single-center datasets, and unrepresentative learning materials might confine their application and generalization in wide practice. Although CADes have been reported to identify polyps in colonoscopic images and videos in real time, their diagnostic performance deserves to be further validated in clinical practice. Read More

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Ileal duplication cyst with giant polypoidal gastric heterotropia.

BMJ Case Rep 2021 Sep 7;14(9). Epub 2021 Sep 7.

Radiodiagnosis, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, India

Enteric duplication cysts (EDCs) are congenital malformations of the gastrointestinal tract. EDCs can present as tubular or spherical cystic lesions of the abdomen. The tubular variant of EDC arises as an outpouching from the bowel wall, whereas the spherical variant rarely shows bowel communication. Read More

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September 2021

Cost-effectiveness analysis of different screening strategies for colorectal cancer in Guangzhou, southern China: a Markov simulation analysis based on natural community screening results.

BMJ Open 2021 09 6;11(9):e049581. Epub 2021 Sep 6.

Non-Communicable Chronic Disease Control and Prevention, Guangzhou Center for Disease Control and Prevention, Guangzhou, Guangdong, China.

Objectives: To evaluate the cost-effectiveness of four different primary screening strategies: high-risk factor questionnaire (HRFQ) alone, single immunochemical faecal occult blood test (iFOBT), double iFOBT and HRFQ+double iFOBT for colorectal cancer (CRC) screening compared with no screening using the Markov model.

Methods: Treeage Pro V.2011 software was used to simulate the Markov model. Read More

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September 2021

Activation of quiescent polypoidal choroidal vasculopathy after membrane peeling vitrectomy for epiretinal membrane: a case report.

BMC Ophthalmol 2021 Sep 6;21(1):321. Epub 2021 Sep 6.

Department of Ophthalmology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, 100730, Beijing, China.

Background: Regular membrane peeling vitrectomy for epiretinal membrane (ERM) patients seldom causes large pigment epithelial detachment (PED). We presented an unusual case of the activation of quiescent polypoidal choroidal vasculopathy (PCV) after membrane peeling vitrectomy for ERM, with an uneven therapeutic process.

Case Presentation: A 75-year-old female patient complained of metamorphopsia in her left eye for 2 years. Read More

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September 2021

Value of Magnifying Chromoendoscopy and Magnifying Optical Enhancement Technology in Classifying Colorectal Polyps: A Prospective Controlled Study.

Gastroenterol Res Pract 2021 27;2021:5533657. Epub 2021 Aug 27.

Department of Gastroenterology, Zhengzhou Central Hospital Affiliated to Zhengzhou University, Zhengzhou University, Zhengzhou, 450000 Henan Province, China.

Background And Aims: Magnifying chromoendoscopy (ME-CE) through the observation of pit patterns is a productive way to distinguish between neoplastic and nonneoplastic polyps. Magnifying optical enhancement technology (ME-OE) is an emerging virtual chromoendoscopy imaging technology and appeared to be a promising approach. However, this information is currently not available. Read More

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Wedge-shape Merocel Pack After Functional Endoscopic Sinus Surgery: Our Experience With 697 Patients.

Med Arch 2021 Jun;75(3):229-233

Division of Otolaryngology, Department of Special Surgery. Jordan University of Science and Technology, King Abdullah University Hospital. Irbid, Jordan.

Background: Chronic rhinosinusitis (CRS) is a disease characterized by inflammation of the paranasal sinus mucosa for a duration of more than 12 weeks. It is one of the most frequently diagnosed chronic diseases that is encountered in everyday practice with an overall prevalence ranges from 7% to 27.

Objective: To evaluate our long-term experience using wedge-shape middle meatal Merocel packing after functional endoscopic sinus surgery (FESS) for chronic rhinosinusitis (CRS). Read More

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An Evaluation of Endoscopic Images from Over 15 Years Prior to the Diagnosis of Autoimmune Gastritis: A Report of Three Patients.

Intern Med 2021 Sep 4. Epub 2021 Sep 4.

Division of Gastroenterology, Department of Internal Medicine 2, Kawasaki Medical School, Japan.

We herein describe three patients whose endoscopic images from over 15 years prior to their diagnosis of autoimmune gastritis (AIG) were available for review. All patients had corpus-dominant atrophic gastritis at the time of the diagnosis of AIG. Previous endoscopic images without severe atrophy showed erythema restricted to the fundic mucosa. Read More

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September 2021

Pedunculated early colorectal cancer with nodal metastasis: a case report.

World J Surg Oncol 2021 Sep 3;19(1):269. Epub 2021 Sep 3.

Department of Surgery, Institute of Gastroenterology, Tokyo Women's Medical University, 8-1, Kawada-cho, Shinjuku-ku, Tokyo, Japan.

Background: Pedunculated polyps are more likely to be amenable to complete resection than non-pedunculated early colorectal cancers and rarely require additional surgery. We encountered a patient with a pedunculated early colorectal cancer that consisted of poorly differentiated adenocarcinoma with lymphatic invasion. We performed an additional bowel resection and found nodal metastasis. Read More

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September 2021

The Workgroup Serrated Polyps and Polyposis (WASP) classification for optical diagnosis of colorectal diminutive polyps with iScan and the impact of the revised World Health Organization (WHO) criteria.

United European Gastroenterol J 2021 Sep 3. Epub 2021 Sep 3.

Department of Gastroenterology and Hepatology, Radboud University Medical Center, Radboud Institute of Health Sciences, Nijmegen, The Netherlands.

Background And Aims: The Workgroup Serrated Polyps and Polyposis (WASP) developed criteria for optical diagnosis of colorectal polyps. The aims of this study were: (1) to improve optical diagnosis of diminutive colorectal polyps, especially SSLs, after training endoscopists in applying WASP criteria on videos of polyps obtained with iScan and (2) to evaluate if the WASP criteria are still useful when polyps are pathologically revised according to the World Health Organization (WHO) 2019 criteria.

Methods: Twenty-one endoscopists participated in a training session and predicted polyp histology on 30 videos of diminutive polyps, before and after training (T and T ). Read More

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September 2021

Digital Clubbing in Hereditary Hemorrhagic Telangiectasia/Juvenile Polyposis Syndrome.

Acta Dermatovenerol Croat 2021 Apr;291(1):56-57

Anna Mrzljak MD, PhD, Department of Gastroenterology and Hepatology, University Hospital Center Zagreb, Kišpatićeva 12, Zagreb; School of Medicine, University of Zagreb, , Salata 3b, 10000 Zagreb, Croatia;

Hereditary hemorrhagic telangiectasia (HHT) (Osler-Weber-Rendu Syndrome) is a rare autosomal dominant vascular disorder characterized by the presence of multiple arteriovenous malformations (AVMs) and recurrent bleeding episodes. The diagnosis is based on the Curacao criteria: (i) spontaneous recurrent epistaxis, (ii) mucocutaneous telangiectasia, (iii) AVMs of visceral organs, and (iv) first degree relatives with a similar condition (1). Due to a common genetic pathway and SMAD4 gene mutation, juvenile polyposis syndrome (JPS) may coexist with HHT (2). Read More

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Dupilumab effectiveness for the treatment of patients with concomitant atopic dermatitis and chronic rhinosinusitis with nasal polyposis.

Dermatol Ther 2021 Sep 1:e15120. Epub 2021 Sep 1.

Section of Dermatology, Department of Clinical Medicine and Surgery, University of Naples Federico II, Italy.

Dupilumab is a fully human monoclonal antibody targeting interleukin (IL) 4 and IL13 pathways. We performed a retrospective observational study to evaluate the efficacy of dupilumab for the treatment of adult patients referred to our department, from January 2019 to May 2021, with a diagnosis of moderate to severe atopic dermatitis (AD) and concomitant chronic rhinosinusitis with nasal polyps (CRSwNP), with a clinical indication for dupilumab treatment. Skin disease activity was assessed using EASI, Numerical Rating Scale (NRS) for pruritus (P-NRS) and sleep (S-NRS), and Dermatology Life Quality Index (DLQI). Read More

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September 2021

Ureteral fibroepithelial polyp: A case report.

Urol Case Rep 2021 Nov 19;39:101815. Epub 2021 Aug 19.

Tottori Prefectural Central Hospital, Tottori, Japan.

Ureteral fibroepithelial polyps are rare, accounting for approximately 2-6% of all ureteral tumors. They can be diagnosed by ultrasonography, computed tomography, and retrograde pyelography; however, diagnosis can be difficult. Management is by resection of the polyp, and endoscopic resection is the standard treatment. Read More

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November 2021

Rare Finding of Inflammatory Fibroid Polyp of the Duodenum: A Complete Diagnostic and Pathological Workup.

Cureus 2021 Jul 30;13(7):e16745. Epub 2021 Jul 30.

Department of General and Clinical Pathology, Forensic Medicine and Deontology, Medical University "Prof. Dr. Paraskev Stoyanov", Varna, BGR.

Inflammatory fibroid polyps (IFP) are solitary benign tumors rarely found in the gastrointestinal (GI) tract. Additionally, duodenal polyps are diagnosed incidentally. We present a case of a 51-year-old female admitted to the department with an initial diagnosis of duodenal polyp on gastroscopy, CT, and positron-emission tomography (PET). Read More

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Binary polyp-size classification based on deep-learned spatial information.

Int J Comput Assist Radiol Surg 2021 Sep 1. Epub 2021 Sep 1.

Graduate School of Informatics, Nagoya University, Furo-cho, Chikusa-ku, Nagoya, 464-8601, Japan.

Purpose: The size information of detected polyps is an essential factor for diagnosis in colon cancer screening. For example, adenomas and sessile serrated polyps that are [Formula: see text] mm are considered advanced, and shorter surveillance intervals are recommended for smaller polyps. However, sometimes the subjective estimations of endoscopists are incorrect and overestimate the sizes. Read More

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September 2021

Cold snare polypectomy without submucosal injection: safety and efficacy in 615 large serrated lesions.

Endosc Int Open 2021 Sep 23;9(9):E1421-E1426. Epub 2021 Aug 23.

Anatomopathology Laboratory, San Isidro, Buenos Aires, Argentina.

 Cold resection is becoming the standard of care for the resection of nonpedunculated colon lesions up to 10 mm in diameter. Sessile serrated adenomas/polyps (SSA/Ps), including those ≥ 10 mm, present various characteristics that make them ideal candidates for cold snare polypectomy (CSP).  A prospectively maintained database was searched retrospectively for consecutive patients with lesions ≥ 10 mm resected between March 2013 and March 2018. Read More

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September 2021

Accuracy of Transvaginal Ultrasound in the Diagnosis of Intrauterine Lesions.

Rev Bras Ginecol Obstet 2021 Jul 30;43(7):530-534. Epub 2021 Aug 30.

Department of Obstetrics and Gynecology, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil.

Objective:  To evaluate the accuracy of transvaginal ultrasound in the diagnosis of intrauterine lesions, using hysteroscopy as the gold standard.

Methods:  This was a prospective observational study with 307 patients. All patients underwent hysteroscopy after a previous transvaginal ultrasound to compare the results. Read More

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Difficult endoscopic resection of a giant esophageal fibrovascular polyp: case report and literature review.

J Int Med Res 2021 Aug;49(8):3000605211039801

Department of Gastroenterology, Beijing Friendship Hospital, Capital Medical University, Beijing, 100050, China.

Esophageal fibrovascular polyp is rare in esophageal neoplasms and usually very large. Here, we present a case of giant esophageal fibrovascular polyp. The patient had dysphagia and choking sensation at presentation. Read More

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Efficacy and safety of dupilumab in patients with uncontrolled severe CRSwNP and a clinical diagnosis of NSAID-ERD: Results from two randomized placebo-controlled phase 3 trials.

Allergy 2021 Aug 30. Epub 2021 Aug 30.

Regeneron Pharmaceuticals, Inc, Tarrytown, NY, USA.

Background: About one-tenth of patients with difficult-to-treat chronic rhinosinusitis with nasal polyps (CRSwNP) have comorbid non-steroidal anti-inflammatory drug-exacerbated respiratory disease (NSAID-ERD). Dupilumab, a fully human monoclonal antibody that blocks the shared interleukin (IL)-4/IL-13 receptor component, is an approved add-on treatment in severe CRSwNP. This post hoc analysis evaluated dupilumab efficacy and safety in CRSwNP patients with/without NSAID-ERD. Read More

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Importance of sessile serrated lesions in a patient with familial adenomatous polyposis.

Clin J Gastroenterol 2021 Aug 29. Epub 2021 Aug 29.

Department of Molecular-Targeting Prevention, Kyoto Prefectural University of Medicine, Kawaramachi-Hirokoji, Kamigyo-ku, Kyoto, 602-8566, Japan.

A 28-year-old male visited hospital because his mother had been diagnosed with familial adenomatous polyposis (FAP) with a pathological variant of the APC gene. Total colonoscopy showed that he has more than 100 polyps distributed throughout the colorectum, and the APC gene variant was also detected. After he was diagnosed with FAP, he received information that surgery was currently the only way to prevent the development of colorectal cancer. Read More

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Utility of the narrow-band imaging international colorectal endoscopic classification for optical diagnosis of colorectal polyp histology in clinical practice: a retrospective study.

BMC Gastroenterol 2021 Aug 28;21(1):336. Epub 2021 Aug 28.

Department of Gastroenterology and Hepatology, Mie University Hospital, 2-174 Edobashi, Tsu, Mie, 514-8507, Japan.

Background: Narrow-band imaging (NBI) highlights the surface structures and vessels of colorectal polyps and is useful for determining the polyp histology. The narrow-band imaging international colorectal endoscopic (NICE) classification is a diagnostic tool for determining colorectal polyp histology based on NBI without optical magnification. In this study, we aimed to investigate the value of each type of the NICE classification for determining colorectal polyp histology using endoscopy data accumulated in a clinical setting. Read More

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A rare case of duodenal-type follicular lymphoma in rectum appearing as hyperplastic polyp with metachronous appearance in duodenum and stomach.

Clin J Gastroenterol 2021 Aug 28. Epub 2021 Aug 28.

Department of Gastroenterology, General Hospital of Nikea-Piraeus 'Agios Panteleimon', Athens, Greece.

Hyperplastic polyps consist a very frequent finding in colonoscopy having a very low potential to malignancy. According to the international guidelines, it is recommended that all polyps should be resected except for diminutive (≤ 5 mm) rectal and rectosigmoid polyps which are predicted with confidence to be hyperplastic. Therefore, in departments where optical diagnosis can be ensured, a "resect and discard" strategy may be implemented for diminutive polyps. Read More

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High Expression of Stem Cell-Related Genes in Polyps with Villous Features and High-Grade Dysplasia Support Malignant Phenotype and Colorectal Carcinogenesis.

Asian Pac J Cancer Prev 2021 Aug 1;22(8):2429-2435. Epub 2021 Aug 1.

Department of Medical Genetics, Faculty of Medicine, Ataturk University, Erzurum, Turkey.

Objective: The aim of this project is to identify the differences in expression levels of stem cell related genes (SCRGs) in normal colon tissue, histopathologically staged colon polyps and colon cancer, and to explain the role of SCRGs in the formation of CC and for contributing the practical usage of SCRGs in the diagnosis and treatment of CC.

Methods: Normal colon tissue, hyperplastic polyps, histopathologically (HGD and LGD) staged tubular, tubulovillous and villous polyps and colon cancer paraffin tissue (FFPE) samples were used. Transcription factor genes (OCT4, KLF4, SOX2, MYC, NANOG, and REX1) and cell surface markers (CD133, LGR5), which are associated with embryonic stem cells, induced pluripotent stem cells, and cancer stem cells, have been selected for measuring expression levels from the selected tissues. Read More

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Automatic Polyp Segmentation in Colonoscopy Images Using a Modified Deep Convolutional Encoder-Decoder Architecture.

Sensors (Basel) 2021 Aug 20;21(16). Epub 2021 Aug 20.

Department of Electrical and Electronic Engineering, Universiti Teknologi PETRONAS, Seri Iskandar 32610, Malaysia.

Colorectal cancer has become the third most commonly diagnosed form of cancer, and has the second highest fatality rate of cancers worldwide. Currently, optical colonoscopy is the preferred tool of choice for the diagnosis of polyps and to avert colorectal cancer. Colon screening is time-consuming and highly operator dependent. Read More

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