Am J Clin Oncol 2021 Jun 9. Epub 2021 Jun 9.
Department of Hepatobiliary and Pancreatic Surgery, Zhongnan Hospital of Wuhan University, Wuhan, Hubei Province Department of Oncology, The Second Xiangya Hospital of Central South University, Changsha, Hunan Province, People's Republic of China Departments of Gastroenterology, Hepatology, and Nutrition Infectious Diseases, Infection Control, and Employee Health Melanoma Medical Oncology Thoracic/Head & Neck Medical Oncology, The University of Texas MD Anderson Cancer Center Department of Biosciences, Rice University Department of Internal Medicine, Baylor College of Medicine, Houston, TX Department of Internal Medicine, Saint Joseph Hospital, Chicago, IL Department of Internal Medicine, University of Missouri, Kansas City, MO Department of Gastroenterology, Sibley Memorial Hospital, Johns Hopkins University, Washington, DC.
Background And Objective: Immune-mediated diarrhea and colitis (IMDC) is a common adverse event in cancer patients receiving immune checkpoint inhibitors (ICIs). Gastrointestinal (GI) infections can co-occur with IMDC, and its impact on the course and outcome of IMDC remains unclear.
Patients And Methods: We retrospectively reviewed cancer patients who received ICIs and developed IMDC between January 2015 and September 2019. Read More