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An 8 channel parallel transmit system with current sensor feedback for MRI-guided interventional applications.

Phys Med Biol 2021 Oct 14. Epub 2021 Oct 14.

School of Biomedical Engineering and Imaging Sciences, King's College London, London, UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND.

Background: Parallel transmit (pTx) has introduced many benefits to MRI with regard to decreased specific absorption rates and improved transmit field homogeneity, of particular importance in applications at higher magnetic field strengths. PTx has also been proposed as a solution to mitigating dangerous RF induced heating of elongated conductive devices such as those used in cardiac interventions. In this work we present a system that can augment a conventional scanner with pTx, in particular for use in interventional MRI for guidewire safety, by adjusting the amplitude and phase of each channel right before the start of the imaging pulses. Read More

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October 2021

The effects of dual modification on functional, microstructural, and thermal properties of tapioca starch.

Food Sci Nutr 2021 Oct 30;9(10):5467-5476. Epub 2021 Jul 30.

Department of Food Science and Technology Islamic Azad University Damghan Iran.

The aim of this study was to investigate the effects of dual modification on the functional, microstructural, and thermal properties of tapioca starch. Tapioca starch was first hydrolyzed by 0.14 M HCl for 0, 6, 12, 18, and 24 hr and then hydroxypropylated by adding 0%, 10%, 20%, and 30% (v/w) propylene oxide. Read More

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October 2021

[Evaluation of fast nucleic acid detection system in severe acute respiratory syndrome coronavirus 2].

Zhonghua Yu Fang Yi Xue Za Zhi 2021 Feb;55(2):219-225

Department of Clinical Laboratory, China-Japan Friendship Hospital, Beijing 100029, China.

To evaluate the performance and application of a fast nucleic acid detection system for testing severe acute respiratory syndrome virus 2 (SARS-COV-2). Clinical samples were collected from February to July 2020 from Beijing Center for Diseases Prevention and Control and the Laboratory Department of China-Japan Friendship Hospital, to evaluate the sensitivity, specificity, anti-interference ability, precision and clinical sample coincidence rate of fast nucleic acid detection system for SARS-CoV-2. The analytical sensitivity was determined by a dilution series of 20 replications for each concentration. Read More

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February 2021

The Effect of Adding a Training Device and Smartphone Application to Traditional Verbal Counseling in Asthmatic Children.

Pulm Ther 2021 Oct 13. Epub 2021 Oct 13.

Department of Clinical Pharmacy, Faculty of Pharmacy, Beni-Suef University, Beni-Suef, Egypt.

Introduction: New training devices have been introduced to help in inhaler counseling by addressing the inspiratory flow through the metered-dose inhaler (MDI), which is the most important problem of the MDI inhalation technique. This study aims to compare the effects of MDI traditional verbal counseling and advanced counseling using training devices with a smartphone application in pediatric asthmatic patients.

Methods: A total of 201 pediatric asthmatic subjects (8-18 years) were divided into two groups: a verbal counseling group, who received only MDI verbal counseling training (n = 101), and an advanced counseling group who received counseling using a training device (Flo-Tone with Trainhaler smartphone application) in addition to the traditional MDI verbal counseling (n = 100). Read More

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October 2021

An in vitro study of an Artocarpus heterophyllus substance as a hepatitis C antiviral and its combination with current anti-HCV drugs.

BMC Complement Med Ther 2021 Oct 12;21(1):260. Epub 2021 Oct 12.

Institute of Tropical Disease, Universitas Airlangga, Surabaya, 60115, Indonesia.

Background: Current therapy of chronic hepatitis C virus (HCV) with direct-acting antivirals (DAAs) has dramatically improved the sustained virologic response (SVR) of affected patients; however, treatment with DAAs remains expensive, and drug-resistant HCV variants remain a threat. As a result, there is still a need to continue to develop affordable and effective drugs for the treatment of HCV. Previously, we have demonstrated that a crude extract from Artocarpus heterophyllus leaves is a potential anti-HCV candidate. Read More

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October 2021

Effect of Rare-Earth Ions on the Optical and PL Properties of Novel Borosilicate Glass Developed from Agricultural Waste.

Materials (Basel) 2021 Sep 27;14(19). Epub 2021 Sep 27.

Radiation Chemistry Department, National Center for Radiation Research & Technology, Atomic Energy Authority, Cairo 11787, Egypt.

There is considerable attention devoted to the use of agricultural waste as a raw material substitute for commercial silica in the development of borosilicate glasses doped with rare earth oxides. Here, we present a novel structure for borosilicate glasses made from rice husk ash with a 25% molar ratio of extracted SiO and doped with neodymium (GRN) or dysprosium (GRD). Adding rare earth oxides to borosilicate glasses by the melt quenching method enhanced optical transmission due to the presence of their tetrahedral geometries. Read More

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September 2021

Dosimetric evaluation of different planning techniques based on flattening filter-free beams for central and peripheral lung stereotactic body radiotherapy.

Biomed Phys Eng Express 2021 Oct 12. Epub 2021 Oct 12.

Department of Radiotherapy, Government Medical College Patiala, Sangrur Road, Patiala, Punjab, 147001, INDIA.

This study aimed to dosimetrically compare and evaluate the flattening filter-free (FFF) photon beam-based three-dimensional conformal radiotherapy (3DCRT), intensity-modulated radiation therapy (IMRT), and volumetric modulated arc therapy (VMAT) for lungstereotactic body radiotherapy (SBRT). RANDO phantom computed tomography (CT) images were used for treatment planning. Gross tumor volumes (GTVs) were delineated in the central and peripheral lung locations. Read More

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October 2021

In vitro activity of imipenem/relebactam against Gram-negative clinical isolates in two Spanish tertiary hospitals.

Rev Esp Quimioter 2021 Oct 13. Epub 2021 Oct 13.

Francisco Javier Candel González. Clinical Microbiology and Infectious Diseases. IdISCC and IML Health Research Institutes. Hospital Clinic San Carlos. Madrid, Spain.

Objective: The aim of this study was to analyze the activity of the imipenem-relebactam combination (IMI/REL) against a collection of multidrug-resist Enterobacterales, Pseudomonas aeruginosa and Acinetobacter baumannii clinical isolates.

Methods: The study was conducted in two tertiary hospitals in Spain and included 192 clinical isolates of these 3 genera (139 resistant and 53 susceptible to IMI). The MICs for IMI with and without REL (at a fixed concentration of 4 mg/L) were determined by a standard broth microdilution method according to international recommendations. Read More

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October 2021

Taguchi optimization of geopolymer concrete produced with rice husk ash and ceramic dust.

Environ Sci Pollut Res Int 2021 Oct 11. Epub 2021 Oct 11.

Department of Materials Science and Engineering, Institute of Science, Kastamonu University, 37150, Kastamonu, Turkey.

Metakaolin, fly ash, and mostly granulated blast furnace slag (GBFS) are traditionally used in the production of geopolymer. This study, adding to the knowledge base on geopolymer concretes as an alternative to cement mixtures, explored an experimental approach that investigates the use of ceramic dust (CD) and rice husk ash (RHA) with high SiO content instead of GBFS in the production of geopolymers. For this purpose, instead of GBFS, RHA at proportions of 0, 5%, 10%, and 15% and CD at proportions of 0, 10%, 20%, and 30% were used in the production of geopolymer concrete. Read More

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October 2021

Long-Lasting Desynchronization Effects of Coordinated Reset Stimulation Improved by Random Jitters.

Front Physiol 2021 24;12:719680. Epub 2021 Sep 24.

Department of Neurosurgery, Stanford University, Stanford, CA, United States.

Abnormally strong synchronized activity is related to several neurological disorders, including essential tremor, epilepsy, and Parkinson's disease. Chronic high-frequency deep brain stimulation (HF DBS) is an established treatment for advanced Parkinson's disease. To reduce the delivered integral electrical current, novel theory-based stimulation techniques such as coordinated reset (CR) stimulation directly counteract the abnormal synchronous firing by delivering phase-shifted stimuli through multiple stimulation sites. Read More

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September 2021

Diffusion-weighted magnetic resonance imaging improves the accuracy of differentiation of benign from malignant peripheral nerve sheath tumors.

World Neurosurg 2021 Oct 5. Epub 2021 Oct 5.

Department of Orthopedic Surgery, Nagoya University Graduate School of Medicine, 65 Tsurumai, Showa, Nagoya, Aichi, 466-8550, Japan.

Objective: In patients with neurofibromatosis type 1 (NF1), it is important to accurately determine when plexiform neurofibroma (pNF) transforms to a malignant peripheral nerve sheath tumor (MPNST). The purpose of this study is to investigate the usefulness of diffusion weighted imaging (DWI) in differentiating pNF and MPNST in NF1 patients.

Methods: Among the NF1 patients who were referred to our hospital between 1985 and 2015, 10 cases of MPNST and 19 cases of pNF were included. Read More

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October 2021

Estimating organic aerosol emissions from cooking in winter over the Pearl River Delta region, China.

Environ Pollut 2021 Oct 2;292(Pt A):118266. Epub 2021 Oct 2.

School of Geography and Tourism, Shaanxi Normal University, Xi'an, Shaanxi, China.

Cooking is an important source of organic aerosols (OA), particularly in urban areas, but it has not been explicitly included in current emission inventories in China. This study estimated the organic aerosol emissions from cooking during winter over the Pearl River Delta (PRD) region, China. Using the retrieved hourly cooking organic aerosol (COA) concentrations at two sites in Hong Kong and Guangzhou, population density, and daily per capita COA emissions, we determined the spatial and temporal distribution of COA emissions over the PRD region based on two approaches by treating COA as non-volatile (NVCOA) and semi-volatile (SVCOA), respectively. Read More

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October 2021

BMP7 reduces the fibrocartilage chondrocyte phenotype.

Sci Rep 2021 Oct 4;11(1):19663. Epub 2021 Oct 4.

Laboratory for Experimental Orthopedics, Department of Orthopedic Surgery, Maastricht University, Universiteitssingel 50, 6229 ER, Maastricht, The Netherlands.

The fibrocartilage chondrocyte phenotype has been recognized to attribute to osteoarthritis (OA) development. These chondrocytes express genes related to unfavorable OA outcomes, emphasizing its importance in OA pathology. BMP7 is being explored as a potential disease-modifying molecule and attenuates the chondrocyte hypertrophic phenotype. Read More

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October 2021

Research Note: Effect of dietary cottonseed meal and soybean oil concentration on digesta passage time and amino acids digestibility in roosters.

Poult Sci 2021 Aug 28;100(11):101446. Epub 2021 Aug 28.

Wen's Food Group Co. Ltd., Guangdong 527439, China.

Two experiments were conducted to study the effect of dietary cottonseed meal (CM) and soybean oil (SO) on passage time of digesta and standardized ileal digestibility (SID) of amino acids (AA). The experimental design was a 2 × 2 factorial arrangement evaluating the levels of CM (20 or 40 %) and SO (0 or 10 %). Experiment 1 estimated the effect of CM and SO on the passage time of digesta. Read More

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The enrichment of honey with fruits enhances its and antioxidant potential and intensifies its antibacterial and antiviral properties.

Food Funct 2021 Oct 4;12(19):8920-8931. Epub 2021 Oct 4.

Department of Chemistry and Food Toxicology, Institute of Food Technology and Nutrition, University of Rzeszow, Ćwiklińskiej 1a St., 35-601 Rzeszow, Poland.

The effect of adding the chokeberry fruit additive to rape honey was studied with regard to the physicochemical properties and biological activity. Two samples of dried powdered fruits were used to enrich the honey (1 and 4% v/v) during creaming. The obtained products were characterized in terms of sugar content, acidity, conductivity, total phenolic, flavonoid and anthocyanin contents and HPTLC polyphenol profiles. Read More

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October 2021

Glucose-Based Fluorinated Surfactants as Additives for the Crystallization of Membrane Proteins: Synthesis and Preliminary Physical-Chemical and Biochemical Characterization.

ACS Omega 2021 Sep 16;6(38):24397-24406. Epub 2021 Sep 16.

Institut des Biomolécules Max Mousseron (UMR 5247 UM-CNRS-ENSCM) & Avignon University, Equipe Chimie Bioorganique et Systèmes amphiphiles, 301 rue Baruch de Spinoza, 84916 Avignon Cedex 9, France.

We report herein the synthesis of a series of fluorinated surfactants with a glucose moiety as a polar head group and whose alkyl chain was varied in length and in fluorine/hydrogen ratio. They were synthesized in two or four steps in 20 to 50% overall yields allowing gram-scale synthesis. Their solubility in water is between 0. Read More

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September 2021

Prevention of low-temperature gelation in milk protein concentrates by calcium-binding salts.

J Dairy Sci 2021 Sep 29. Epub 2021 Sep 29.

Department of Food Science, The Pennsylvania State University, University Park 16802. Electronic address:

The objective of this study was to determine the effect of adding low concentrations of calcium-binding salts on the prevention of low-temperature gelation in milk protein concentrates (MPC). The MPC were created by a combination of ultrafiltration and diafiltration, standardized from 14 to 17% (wt/vol) protein content and mixed with one of 5 calcium-binding salts (sodium citrate, sodium hexametaphosphate, sodium polyphosphate, sodium pyrophosphate, and sodium monophosphate) adjusted to a pH of 6.75. Read More

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September 2021

PD-L1 expression evaluated by 22C3 antibody is a better prognostic marker than SP142/SP263 antibodies in breast cancer patients after resection.

Sci Rep 2021 Oct 1;11(1):19555. Epub 2021 Oct 1.

Division of Breast Surgery, Department of Surgery, Seoul St Mary's Hospital, College of Medicine, The Catholic University of Korea, 222 Banpo-daero, Seocho-gu, Seoul, Korea.

Immune checkpoint inhibitors (ICI) have demonstrated efficacy in the treatment of solid cancers. However, there is no unified predictive biomarker available for ICIs. We aimed to compare the prognostic impact of using three PD-L1 antibodies (SP142, SP263, and 22C3) for immunohistochemical (IHC) analysis. Read More

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October 2021

A simple nomogram for identifying individuals at high risk of undiagnosed diabetes in rural population.

Diabetes Res Clin Pract 2021 Sep 28;180:109061. Epub 2021 Sep 28.

National Institute of Nutrition, 48B Tang Bat Ho Street, Hanoi, Vietnam.

Aims: To sought for an easily applicable nomogram for detecting individuals at high risk of undiagnosed type 2 diabetes.

Methods: The development cohort included 2542 participants recruited randomly from a rural population in 2011.The glycemic status of subjects was determined using the fasting plasma glucose test and the oral glucose tolerance test. Read More

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September 2021

A Tuberculosis Outbreak at a School - Xinjiang Uygur Autonomous Region, China, 2019.

China CDC Wkly 2020 Nov;2(46):881-883

Chinese Center for Disease Control and Prevention, Beijing, China.

What Is Already Known About This Topic?: Worldwide, tuberculosis (TB) continues to be the most important cause of death from a single infectious agent, and China has a high TB burden. Although the reported incidence of TB in students is lower than that in general population, TB outbreaks in schools have continuously been reported in the past years, suggesting that schools are a high-risk setting for TB transmission.

What Is Added By This Report?: In total, 31 TB patients were founded in students. Read More

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November 2020

Ghrelin Immunoreactive Cell Amounts in the Abomasum in 4-Month-Old Calves by Feeding Different Amounts of Prebiotics and New Synbiotics.

Vet Med Int 2021 20;2021:5542372. Epub 2021 Sep 20.

St. John Fisher College, Biology Department, 3690 East Ave, Rochester, New York 14618, USA.

The study aim was to determine prebiotic (inulin) and new synbiotic (inulin and varied dosage effects, during food breakdown-abomasum immunoreactive (IR) cell amount and cold carcass weight. Ghrelin is synthesized in the fundus region of the stomach. In the gastrointestinal system, ghrelin affects multiple functions, including secretion of gastric acid, gastric motility, and pancreatic protein output. Read More

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September 2021

Postmortem investigations and identification of multiple causes of child deaths: An analysis of findings from the Child Health and Mortality Prevention Surveillance (CHAMPS) network.

PLoS Med 2021 Sep 30;18(9):e1003814. Epub 2021 Sep 30.

College of Health and Medical Sciences, Haramaya University, Harar, Ethiopia.

Background: The current burden of >5 million deaths yearly is the focus of the Sustainable Development Goal (SDG) to end preventable deaths of newborns and children under 5 years old by 2030. To accelerate progression toward this goal, data are needed that accurately quantify the leading causes of death, so that interventions can target the common causes. By adding postmortem pathology and microbiology studies to other available data, the Child Health and Mortality Prevention Surveillance (CHAMPS) network provides comprehensive evaluations of conditions leading to death, in contrast to standard methods that rely on data from medical records and verbal autopsy and report only a single underlying condition. Read More

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September 2021

Cardio-ankle vascular index as a predictor of major adverse cardiovascular events in metabolic syndrome patients.

Clin Cardiol 2021 Sep 29. Epub 2021 Sep 29.

Division of Cardiology, Department of Medicine, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.

Background: Arterial stiffness, as reflected in the cardio-ankle vascular index (CAVI), is a risk factor for major adverse cardiovascular events (MACEs).

Hypothesis: Combining CAVI and metabolic syndrome (MetS) may enhance prediction of MACEs in a general adult population.

Methods: A total of 3807 employees of the Electricity Generating Authority of Thailand were enrolled in a longitudinal health study during 2007-2008. Read More

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September 2021

Development of novel experimental and modelled low density polyethylene (LDPE)-water partition coefficients for a range of hydrophobic organic compounds.

Environ Pollut 2021 Sep 22;291:118223. Epub 2021 Sep 22.

School of Civil Engineering, Lanzhou University of Technology, 287 Langongping, Lanzhou, 730050, China.

Knowledge about partitioning constants of hydrophobic organic compounds (HOCs) between the polymer and aqueous phases is critical for assessing chemical environmental fate and transport. The conventional experimental method is characterized by large discrepancies in the measured values due to the limited water solubility of HOCs and other associated issues. In the current work, a novel three-phase partitioning system was evaluated to determine accurate low-density polyethylene (LDPE)-water partition coefficients (K). Read More

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September 2021

HfS thin films deposited at room temperature by an emerging technique, solution atomic layer deposition.

Dalton Trans 2021 Sep 28;50(37):13066-13072. Epub 2021 Sep 28.

Chemistry of Thin Film Materials (CTFM), Interdisciplinary Center of Nanostructured Films (IZNF), Friedrich Alexander University of Erlangen-Nuremberg, Cauerstr. 3, 91058 Erlangen, Germany.

As a member of the two-dimensional metal dichalcogenide family, HfS has emerged as a promising material for various optoelectronic applications. Atomic layer deposition is widely used in microelectronics manufacturing with unique properties in terms of accurate thickness control and high conformality. In this work, a simple and versatile method based on the atomic layer deposition principles is presented to generate hafnium disulfide from the solution phase ('solution ALD' or sALD). Read More

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September 2021

Antibacterial Biodegradable Films Based on Alginate with Silver Nanoparticles and Lemongrass Essential Oil-Innovative Packaging for Cheese.

Nanomaterials (Basel) 2021 Sep 13;11(9). Epub 2021 Sep 13.

Faculty of Applied Chemistry and Material Science, University Politehnica of Bucharest, 060042 Bucharest, Romania.

Replacing the petroleum-based materials in the food industry is one of the main objectives of the scientists and decision makers worldwide. Biodegradable packaging will help diminish the environmental impact of human activity. Improving such biodegradable packaging materials by adding antimicrobial activity will not only extend the shelf life of foodstuff, but will also eliminate some health hazards associated with food borne diseases, and by diminishing the food spoilage will decrease the food waste. Read More

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September 2021

Effect of Silver Modification on the Photoactivity of Titania Coatings with Different Pore Structures.

Nanomaterials (Basel) 2021 Aug 30;11(9). Epub 2021 Aug 30.

Centre for Colloid Chemistry, Department of Physical Chemistry and Materials Science, Faculty of Chemical Technology and Biotechnology, Budapest University of Technology and Economics, H-1521 Budapest, Hungary.

Nanostructured photoactive systems are promising for applications such as air and water purification, including self-cleaning coatings. In this study, mesoporous TiO sol-gel coatings with different pore structures were prepared and modified with silver by two methods: the "mixing" method by adding AgNO to the precursor sol, and the "impregnation" method by immersing the samples in AgNO solution (0.03 and 1 M) followed by heat treatment. Read More

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First and Second Dissociation Enthalpies in Bi-Component Crystals Consisting of Maleic Acid and L-Phenylalanine.

Molecules 2021 Sep 21;26(18). Epub 2021 Sep 21.

Centro de Química Estrutural, Faculdade de Ciências, Universidade de Lisboa, 1749-016 Lisboa, Portugal.

The energetics of the stepwise dissociation of a A:B bi-component crystal, according to A:B(cr) → A:B(cr) + B(cr) and A:B(cr) → A(cr) + B(cr), was investigated using MA:Phe and MA:Phe (MA = maleic acid; Phe = L-phenylalanine) as model systems. The enthalpy changes associated with these sequential processes and with the overall dissociation reaction A:B(cr) → A(cr) + 2B(cr) were determined by solution calorimetry. It was found that they are all positive, indicating that there is a lattice enthalpy gain when MA:Phe is formed, either from the individual precursors or by adding Phe to MA:Phe. Read More

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September 2021

Effect of Calcium Compound Type and Dosage on the Properties of Acid Rennet Goat's Milk Gels.

Molecules 2021 Sep 13;26(18). Epub 2021 Sep 13.

Department of Dairy Technology, Institute of Food Technology and Nutrition, College of Natural Sciences, University of Rzeszow, Ćwiklińskiej 2D, 35-601 Rzeszów, Poland.

The aim of this study was to determine the effect of adding calcium compounds to processed goat's milk, and on the properties of acid rennet goat's milk gels, which are a middle product obtained in the manufacture of acid rennet cheese. The properties of the gels directly affect the quality of acid rennet cheeses. The analysis of raw goat's milk was carried out, then acid rennet gels were produced with the addition of six different calcium compounds (chloride, citrate, bisglycinate, gluconate, lactate, and carbonate). Read More

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September 2021

Behaviour of and Natural Microflora during the Manufacture of Riojano Chorizo (Spanish Dry Cured Sausage).

Microorganisms 2021 Sep 15;9(9). Epub 2021 Sep 15.

Food Technology Department, CIVA Research Center, University of La Rioja, Madre de Dios 53, 26006 Logroño, Spain.

Riojano chorizo is a dry cured sausage manufactured with traditional technologies without adding starter cultures at low temperatures. Its characteristics differ from other types of chorizo since sugars and nitrites are no added and processing temperatures are low- This work evaluates the behaviour of during the processing of inoculated Riojano chorizo as well as the natural microflora that can play a technological role or be of interest as indicators. The sausage mixture was inoculated with a cocktail of three selected strains of (CECT 932, CECT 934 and CECT 4032) (4 log CFU/g) and after processed following the traditional production method. Read More

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September 2021