Menopause 2021 Mar 15. Epub 2021 Mar 15.
School of Public Health and Preventive Medicine, Monash University, Melbourne, Australia Gynaecological Oncology Service, Chris O'Brien Lifehouse, Sydney, Australia Department of Obstetrics and Gynaecology, University of Melbourne and The Royal Women's Hospital, Melbourne, Australia Gynae-oncology and Dysplasia Unit, The Royal Women's Hospital, Melbourne, Australia Basser Center for BRCA, University of Pennsylvania, Philadelphia, PA Prince of Wales Clinical School, University of New South Wales, Sydney, Australia Crown Princess Mary Cancer Centre, Westmead Hospital, Sydney, Australia Gynaecology Research Centre, The Royal Women's Hospital, Melbourne, Australia.
Objective: Premenopausal risk-reducing bilateral salpingo-oophorectomy (RRBSO) may impair sexual function, but the nature and degree of impairment and impact of estrogen therapy on sexual function and sexually related personal distress after RRBSO are uncertain.
Methods: Prospective observational study of 73 premenopausal women at elevated risk of ovarian cancer planning RRBSO and 68 premenopausal controls at population risk of ovarian cancer. Participants completed the Female Sexual Function Index and the Female Sexual Distress Scale-Revised. Read More