484,972 results match your criteria depressive symptoms


The measure of precarious employment and its impact on the mental health of workers: A systematic review 2007-2020.

Work 2022 Aug 6. Epub 2022 Aug 6.

Research Group on Health Inequalities, Environment, and Employment Conditions Network (GREDS-EMCONET), Department of Political and Social Science, Universitat Pompeu Fabra, Barcelona, Spain.

Background: Precarious employment conditions can influence the worker's mental health; however, there is no consensus regarding the definition of precarious employment or the way it is measured.

Objective: The objective is to identify existing research of the conceptual framework, the ways to measure precarious employment and its impact on the mental health of workers.

Methods: A systematic review with the strategic search for observational-empirical and qualitative studies published between 2007 and 2020 in Embase, Scopus and PubMed, full text, in English and Spanish. Read More

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Exercise as a Potential Therapeutic Strategy to Target the Clinical Link Between Depression and Alzheimer's Disease: A Narrative Review.

J Alzheimers Dis 2022 Aug 9. Epub 2022 Aug 9.

Mitchell Center for Neurodegenerative Diseases, Department of Neurology, University ofTexas Medical Branch at Galveston, Galveston, TX, USA.

Alzheimer's disease (AD) and major depressive disorder (MDD) affect millions worldwide and both cause significant morbidity and mortality. While clinically distinctive, patients with MDD can present with memory dysfunction and patients with AD commonly report symptoms of depression. Additionally, brain pathology in MDD and AD both demonstrate decreased hippocampal volumes, and severe disease is associated with smaller hippocampal volumes in both disorders. Read More

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Evaluating a web-based computer-tailored physical activity intervention for those living with and beyond lung cancer (ExerciseGuide UK): protocol for a single group feasibility and acceptability study.

Pilot Feasibility Stud 2022 Aug 13;8(1):182. Epub 2022 Aug 13.

Wolfson Palliative Care Research Centre, Hull York Medical School, University of Hull, Allam Medical Building 3rd Floor, Cottingham Road, Kingston-Upon-Hull, East Yorkshire, HU6 7RX, UK.

Background: Lung cancer is the leading cause of cancer-related death globally. Physical activity and exercise provide unequivocal benefits to those living with and beyond lung cancer. However, few of those living with and beyond cancer meet the national physical activity guidelines. Read More

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Genetic variants of interleukin 1B and 6 are associated with clinical outcome of surgically treated lumbar degenerative disc disease.

BMC Musculoskelet Disord 2022 Aug 13;23(1):774. Epub 2022 Aug 13.

National Center for Spinal Disorders, Kiralyhago street 1, Budapest, 1126, Hungary.

Background: Successfully surgically treating degenerative disc diseases can be challenging to the spine surgeons, the long-term outcome relies on both the physical and mental status of the patient before and after treatment. Numerous studies underlined the role of inflammatory cytokines - like interleukin 1B and 6 - in the development of chronic diseases such as failed back surgery syndrome (FBSS) and major depressive disorder (MDD) which alter the outcome after spinal surgery. Our aim was to evaluate the associations of IL6 and IL1B gene polymorphisms with the long-term outcome of degenerative lumbar spine surgeries. Read More

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Hospital nursing factors associated with decreased odds of mortality in older adult medicare surgical patients with depression.

BMC Geriatr 2022 Aug 13;22(1):665. Epub 2022 Aug 13.

Center for Health Outcomes and Policy Research, University of Pennsylvania School of Nursing, 418 Curie Blvd., 2L, Philadelphia, PA, 19104, USA.

Background: Depression is common, costly, and has deleterious effects in older adult surgical patients. Little research exists examining older adult surgical patient outcomes and depression and the potential for nursing factors to affect these outcomes. The purpose of this study was to determine the relationship between hospital nursing resources, 30-day mortality; and the impact of depression on this relationship. Read More

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Characterizing risky alcohol use, cigarette smoking, e-cigarette use, and physical inactivity among cancer survivors in the USA-a cross-sectional study.

J Cancer Surviv 2022 Aug 14. Epub 2022 Aug 14.

Division of Hematology and Oncology, UC Davis Comprehensive Cancer Center, 4501 X Street, Suite 3016, Sacramento, CA, 95817, USA.

Purpose: Unhealthy lifestyle behaviors are associated with inferior health outcomes among cancer survivors, including increased mortality. It is crucial to identify vulnerable subgroups, yet investigations have been limited. Thus, this study aimed to examine sociodemographic and clinical characteristics associated with risky health behaviors among cancer survivors. Read More

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Comment on "The effects of rational emotive behavior therapy for depressive symptoms in adults with congenital heart disease."

Heart Lung 2022 Aug 10. Epub 2022 Aug 10.

Gouri Devi Institute of Medical Sciences & Hospital, Durgapur, West Bengal 713212, India. Electronic address:

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[Consumption of legal and illegal drugs and depressive symptoms in older adults during the SARS-CoV-2 pandemic in Mexico].

Rev Esp Geriatr Gerontol 2022 Jul 22. Epub 2022 Jul 22.

Instituto de Ciencias de la Salud, Universidad Veracruzana, Xalapa, Veracruz, México.

Background: The health risks faced by older adults are diverse; however, little has been explored about the use and abuse of psychoactive substances in this population. The seclusion imposed by the situation that prevails due to SARS-CoV-2 has increased the feelings of loneliness, isolation and sadness associated with this age, which makes them a risk factor for drug use.

Objective: To analyze the consumption of legal and illegal drugs in people over 60 years of age who are Facebook users and its relationship with symptoms of depression during the SARS-CoV-2 pandemic. Read More

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Chronic fluoxetine treatment of socially isolated rats modulates prefrontal cortex proteome.

Neuroscience 2022 Aug 10. Epub 2022 Aug 10.

Proteomics and Biomarkers, Max Planck Institute of Psychiatry, Munich, Germany.

Fluoxetine (Flx) is the most commonly used antidepressant to treat major depressive disorder. However, its molecular mechanisms of action are not defined as yet. A comparative proteomic approach was used to identify proteome changes in the prefrontal cortex (PFC) cytosolic and non-synaptic mitochondria (NSM)-enriched fractions of adult male Wistar rats following chronic social isolation (CSIS), a rat model of depression, and Flx treatment in CSIS and control rats, using liquid chromatography online tandem mass spectrometry. Read More

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American Association of Clinical Endocrinology Clinical Practice Guideline: Developing a Diabetes Mellitus Comprehensive Care Plan-2022 Update.

Endocr Pract 2022 Aug 10. Epub 2022 Aug 10.

University of South Carolina School of Medicine-Greenville, Prisma Health System, Greenville, South Carolina.

Objective: The objective of this clinical practice guideline is to provide updated and new evidence-based recommendations for the comprehensive care of persons with diabetes mellitus to clinicians, diabetes-care teams, other health care professionals and stakeholders, and individuals with diabetes and their caregivers.

Methods: The American Association of Clinical Endocrinology (AACE) selected a task force of medical experts and staff who updated and assessed clinical questions and recommendations from the prior 2015 version of this guideline and conducted literature searches for relevant scientific papers published from January 1, 2015, through May 15, 2022. Selected studies from results of literature searches composed the evidence base to update 2015 recommendations as well as to develop new recommendations based on review of clinical evidence, current practice, expertise, and informal consensus, according to established AACE protocol for guideline development. Read More

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Applying the Rapid OPPERA Algorithm to Predict Persistent Pain Outcomes among a Cohort of Women Undergoing Breast Cancer Surgery.

J Pain 2022 Aug 10. Epub 2022 Aug 10.

Department of Anesthesiology, Perioperative, and Pain Medicine, Brigham & Women's Hospital, Harvard Medical School.

Persistent post-mastectomy pain after breast surgery is variable in duration and severity across patients, due in part to interindividual variability in pain processing. The Rapid OPPERA Algorithm (ROPA) empirically identified three clusters of patients with different risk of chronic pain based on four key psychophysical and psychosocial characteristics. We aimed to test this type of group-based clustering within in a perioperative cohort undergoing breast surgery to investigate differences in postsurgical pain outcomes. Read More

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Differences across sexes on head-twitch behavior and 5-HT receptor signaling in C57BL/6J mice.

Neurosci Lett 2022 Aug 10:136836. Epub 2022 Aug 10.

Department of Physiology & Biophysics, Virginia Commonwealth University School of Medicine, Richmond, VA, 23298, USA. Electronic address:

Psychedelics, also known as classical hallucinogens, affect processes related to perception, cognition and sensory processing mostly via the serotonin 5-HT receptor (5-HTR). This class of psychoactive substances, which includes lysergic acid diethylamide (LSD), psilocybin, mescaline and the substituted amphetamine 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI), is receiving renewed attention for their potential therapeutic properties as it relates to psychiatric conditions such as depression and substance use disorders. Current studies focused on the potentially clinical effects of psychedelics on human subjects tend to exclude sex as a biological variable. Read More

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Safety and efficacy of prophylactic levetiracetam for prevention of epileptic seizures in the acute phase of intracerebral haemorrhage (PEACH): a randomised, double-blind, placebo-controlled, phase 3 trial.

Lancet Neurol 2022 Sep;21(9):781-791

Stroke Centre, Lyon University Hospital, Lyon, France; University Claude Bernard Lyon 1, Research on Healthcare Performance (RESHAPE), INSERM U1290, Lyon, France.

Background: The incidence of early seizures (occurring within 7 days of stroke onset) after intracerebral haemorrhage reaches 30% when subclinical seizures are diagnosed by continuous EEG. Early seizures might be associated with haematoma expansion and worse neurological outcomes. Current guidelines do not recommend prophylactic antiseizure treatment in this setting. Read More

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September 2022

Comparative transcriptomics of two coral holobionts collected during the 2017 El Niño heat wave reveal differential stress response mechanisms.

Mar Pollut Bull 2022 Aug 11;182:114017. Epub 2022 Aug 11.

Department of Biology, Hong Kong Baptist University, Hong Kong, China; Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou), Guangzhou 511458, China; HKBU Institute of Research and Continuing Education, Virtual University Park, Shenzhen, China. Electronic address:

Although coral species exhibit differential susceptibility to stressors, little is known about the underlying molecular mechanisms. Here we compared scleractinian corals Montipora peltiformis and Platygyra carnosa collected during the 2017 El Niño heat wave. Zooxanthellae density and chlorophyll a content declined and increased substantially during and after heat stress event, respective. Read More

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Can integrating the Memory Support Intervention into cognitive therapy improve depression outcome? A randomized controlled trial.

Behav Res Ther 2022 Aug 6;157:104167. Epub 2022 Aug 6.

University of California, Berkeley, CA, USA. Electronic address:

We investigated if improving a patient's memory for the content of their treatment, via the Memory Support Intervention, improves illness course and functional outcomes. The platform for investigating this question was major depressive disorder (MDD) and cognitive therapy (CT). Adults diagnosed with MDD (N = 178) were randomly allocated to CT + Memory Support (n = 91) or CT-as-usual (n = 87). Read More

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Selective serotonin reuptake inhibitors and preeclampsia: A quality assessment and meta-analysis.

Pregnancy Hypertens 2022 Aug 6;30:36-43. Epub 2022 Aug 6.

University of Iowa Department of Obstetrics and Gynecology, 200 Hawkins Dr., Iowa City IA 52242, United States. Electronic address:

Serotonin modulates vascular, immune, and neurophysiology and is dysregulated in preeclampsia. Despite biological plausibility that selective serotonin reuptake inhibitors (SSRIs) prevent preeclampsia pathophysiology, observational studies have indicated increased risk and providers may be hesitant. The objective of this meta-analysis and quality assessment was to evaluate the evidence linking SSRI use in pregnancy to preeclampsia/gestational hypertension. Read More

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Relationship between chronic obstructive pulmonary disease and cognition in an aging population.

J Psychosom Res 2022 Aug 4;161:111000. Epub 2022 Aug 4.

Department of Psychiatry, The University of Texas Southwestern Medical Center, Dallas, TX, USA. Electronic address:

Objectives: Chronic obstructive pulmonary disease (COPD) is a common and severe respiratory illness. Prior research suggests that COPD may be associated with depression as well as cognitive impairment and increased risk of dementia. Many studies to date have been relatively small, have largely relied on global screening measures to identify cognitive impairment, and have not examined the potential role of comorbid depression on cognition. Read More

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Effects of an integrated childbirth education program to reduce fear of childbirth, anxiety, and depression, and improve dispositional mindfulness: A single-blind randomised controlled trial.

Midwifery 2022 Jul 27;113:103438. Epub 2022 Jul 27.

School of Nursing, College of Nursing, Taipei Medical University, Taipei, Taiwan; Nursing Department, Taipei Medical University Hospital, 250 Wuxing St. Taipei 11031, Taiwan. Electronic address:

Objective: To evaluate the effects of an integrated childbirth education intervention on reducing childbirth fear, anxiety, and depression, and improving dispositional mindfulness.

Design: A two-arm parallel, single-blind randomised controlled trial.

Setting: A teaching hospital in Northern Taiwan. Read More

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The clinical and psychosocial correlates of self-stigma among people with schizophrenia spectrum disorders across cultures: A systematic review and meta-analysis.

Schizophr Res 2022 Aug 10;248:64-78. Epub 2022 Aug 10.

Douglas Research Centre, Montreal, Canada; Department of education and pedagogy-career counseling, Université du Québec À Montréal, Montreal, Canada. Electronic address:

Background: Individuals with schizophrenia spectrum disorders (SSD) are at heightened risk of experiencing self-stigma, and some cultures are more stigmatizing towards SSD than others. The first purpose of this review is to provide an estimate of the relationship between self-stigma and clinical and psychosocial outcomes. The second purpose is to examine how these relationships vary across cultures. Read More

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Complementary and Integrative Medicine for Neurocognitive Disorders and Caregiver Health.

Curr Psychiatry Rep 2022 Aug 13. Epub 2022 Aug 13.

Department of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine, University of California, Los Angeles; 760 Westwood Plaza, Los Angeles, CA, 90095, USA.

Purpose Of Review: Integrative medicine is the practice of combining conventional medical treatments with "alternative" or "complementary" therapies. Integrative psychiatry is a holistic, person-centered approach to neuropsychiatric disorders that emphasizes a person's physical, emotional, interpersonal, behavioral, nutritional, environmental, and spiritual dimensions to achieve well-being. Older adults are more prone to physical injury, interpersonal loss, chronic illnesses, and physical and cognitive decline that can manifest as anxiety, depression, with functional decline and inability to care for self. Read More

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Lumbar spinal stenosis is a risk factor for the development of dementia: locomotive syndrome and health outcomes in the Aizu cohort study.

Eur Spine J 2022 Aug 13. Epub 2022 Aug 13.

Department of Orthopaedic Surgery, Fukushima Medical University School of Medicine, 1-Hikarigaoka, Fukushima City, 960-1295, Japan.

Purpose: It remains unclear whether musculoskeletal diseases are risk factors for dementia development. This prospective cohort study of community-dwelling residents aimed to clarify the impact of lumbar spinal stenosis (LSS) on dementia development.

Methods: We included participants aged ≥ 65 years from the Locomotive Syndrome and Health Outcomes in the Aizu cohort study. Read More

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Geotemporal analysis of perinatal care changes and maternal mental health: an example from the COVID-19 pandemic.

Arch Womens Ment Health 2022 Aug 13. Epub 2022 Aug 13.

Department of Psychiatry, Columbia University Irving Medical Center, New York, NY, USA.

Our primary objective was to document COVID-19 induced changes to perinatal care across the USA and examine the implication of these changes for maternal mental health. We performed an observational cross-sectional study with convenience sampling using direct patient reports from 1918 postpartum and 3868 pregnant individuals collected between April 2020 and December 2020 from 10 states across the USA. We leverage a subgroup of these participants who gave birth prior to March 2020 to estimate the pre-pandemic prevalence of specific birthing practices as a comparison. Read More

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Content agreement of depressive symptomatology in children and adolescents: a review of eighteen self-report questionnaires.

Eur Child Adolesc Psychiatry 2022 Aug 13. Epub 2022 Aug 13.

Department of Medicine, Universitat Internacional de Catalunya (UIC), C/Josep Trueta S/N (Hospital Universitari General de Catalunya, Sant Cugat del Vallès, 08195, Barcelona, Spain.

Identifying major depression in children and adolescents is more challenging than in adults. Questionnaires are often used for screening or guiding clinical assessment. Several instruments of different lengths are used as equivalent measures in diagnostic decisions. Read More

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THE STATE OF TOXIN-RELEASING FUNCTION OF THE KIDNEYS IN THE SYNDROME OF ENDOGENOUS INTOXICATION OF PURULENT-SEPTIC ORIGIN IN PATIENTS WITH DIABETES MELLITUS.

Wiad Lek 2022 ;75(6):1724-1727

BUKOVINIAN STATE MEDICAL UNIVERSITY, CHERNIVTSI, UKRAINE.

Objective: The aim: To investigate the state of renal toxin excretory function in EIS of purulent-septic genesis in patients with diabetes mellitus-2 under the condition of infusion load with low-volume Ringer's solution.

Patients And Methods: Materials and methods: The research belongs to the opened, randomized, prospective and controlled studies. The study group was consisted of patients with diabetes mellitus-2 complicated syndrome of endogenous intoxication of purulent-septic origin (CDSEI). Read More

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January 2022

Prevalence and risk factors of cognitive frailty in community-dwelling older adults with diabetes: A systematic review and meta-analysis.

Diabet Med 2022 Aug 12:e14935. Epub 2022 Aug 12.

School of Nursing, Chongqing Medical University, Chongqing, PR China.

Aims: Cognitive frailty can increase the risk of adverse health outcomes in older adults. Estimates of the prevalence of cognitive frailty among older adults with diabetes varied widely in literature. This study aimed to conduct a systematic review and meta-analysis to assess the pooled prevalence of cognitive frailty and risk factors in community-dwelling older adults with diabetes, providing evidence for healthcare professionals to better understand the status of cognitive frailty and help develop effective interventions. Read More

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Prevalence of Body Dysmorphic Disorder in an Otolaryngology-Head and Neck Surgery Clinic.

Ann Otol Rhinol Laryngol 2022 Aug 12:34894221118772. Epub 2022 Aug 12.

Facial Plastic and Reconstructive Surgery, Department of Otolaryngology-Head and Neck Surgery, The Pennsylvania State University, College of Medicine, Hershey, PA, USA.

Objective: To analyze the prevalence of body dysmorphic disorder (BDD) in a general otolaryngology population presenting to an outpatient clinic.

Study Design: Prospective prevalence study.

Setting: Single tertiary academic otolaryngology clinic. Read More

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The interaction between depression diagnosis and BMI is related to altered activation pattern in the right inferior frontal gyrus and anterior cingulate cortex during food anticipation.

Brain Behav 2022 Aug 12:e2695. Epub 2022 Aug 12.

Department of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania.

Background: Depression and overweight/obesity often cooccur but the underlying neural mechanisms for this bidirectional link are not well understood.

Methods: In this functional magnetic resonance imaging study, we scanned 54 individuals diagnosed with depressive disorders (DD) and 48 healthy controls (HC) to examine how diagnostic status moderates the relationship between body mass index (BMI) and brain activation during anticipation and pleasantness rating of food versus nonfood stimuli.

Results: We found a significant BMI-by-diagnosis interaction effect on activation in the right inferior frontal gyrus (RIFG) and anterior cingulate cortex (ACC) during food versus nonfood anticipation (p < . Read More

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