80,675 results match your criteria depression scale


A positron emission tomography study of the serotonin1B receptor effect of electroconvulsive therapy for severe major depressive episodes.

J Affect Disord 2021 Jul 17;294:645-651. Epub 2021 Jul 17.

Department of Neuropsychiatry, Graduate School of Medicine, Nippon Medical School, Tokyo, Japan.

Background: Electroconvulsive therapy (ECT) is an effective treatment for depressive disorders, although its molecular mechanism of action is unknown. The serotonin 1B (5-HT) receptor is a potential target for treatment of depression and low 5-HT receptor binding in limbic regions has been reported in previous positron emission tomography (PET) studies of depression.

Methods: The objective of this longitudinal PET study was to examine the effect of ECT for depression on 5-HT receptor binding. Read More

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Feasibility, acceptability, and potential effectiveness of an online expressive writing intervention for COVID-19 resilience.

Complement Ther Clin Pract 2021 Jul 27;45:101460. Epub 2021 Jul 27.

Duke Integrative Medicine, 3475 Erwin Road, Durham, NC, 27705, USA. Electronic address:

Background & Purpose: The COVID-19 pandemic has negatively impacted mental health in the general population. In this trial, our objective was to assess whether a 6-week expressive writing intervention improves resilience in a sample from the general population in the midst of the COVID-19 pandemic.

Materials & Methods: This 6-week trial was conducted online. Read More

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The joint effects of clinically relevant depressive symptoms and cardiovascular risk factors on incident cardiovascular disease among older adults in the community.

J Psychosom Res 2021 Jul 16;149:110572. Epub 2021 Jul 16.

Amsterdam UMC, Vrije Universiteit Amsterdam, Department of Psychiatry, Amsterdam Public Health Research Institute, Amsterdam, the Netherlands; GGZ inGeest Specialized Mental Health Care, Amsterdam, the Netherlands. Electronic address:

Objective: To determine if there is a synergistic effect between clinically relevant depressive symptoms and cardiovascular risk factors that disproportionately increases the risk of cardiovascular disease (CVD) among older adults with depressive symptoms.

Methods: Data were obtained from the Longitudinal Aging Study Amsterdam, a longitudinal cohort study. N = 3091 respondents with up to seven years of follow-up were included. Read More

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Can dogs and cats really help our spinal cord stimulation patients?

Clin Neurol Neurosurg 2021 Jul 22;208:106831. Epub 2021 Jul 22.

Department of Neuroscience and Experimental Therapeutics, Albany Medical College, Albany, NY, USA; Department of Neurosurgery, Albany Medical College, Albany, NY, USA. Electronic address:

Objectives: Pet ownership has been shown to decrease morbidity and mortality in several aspects of health but has not been studied in chronic pain patients. We evaluate whether subjects who underwent spinal cord stimulation (SCS) and own a pet have improved outcomes compared to non-pet owners.

Methods: After obtaining IRB approval, we re-contacted 38 subjects who underwent SCS surgery with preoperative and 1-year postoperative data on Numerical Rating Scale (NRS), McGill Pain Questionnaire (MPQ), Oswestry Disability Index (ODI), Beck Depression Inventory (BDI), and Pain Catastrophizing scale (PCS). Read More

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Effects of Ankle Continuous Passive Motion on Soleus Hypertonia in Individuals with Cerebral Palsy: A Case Series.

Biomed J 2021 Jul 28. Epub 2021 Jul 28.

School of Physical Therapy and Graduate Institute of Rehabilitation Science, College of Medicine, Chang Gung University, No.259, Wen-hua 1st Rd., Guishan Dist., Taoyuan, Taiwan; Healthy Aging Research Center, Chang Gung University, No.259, Wenhua 1st Rd., Guishan Dist., Taoyuan, Taiwan; Neuroscience Research Center, Chang Gung Memorial Hospital, Linkou Medical Center, No.5, Fuhsing Str., Guishan Dist., Taoyuan, Taiwan. Electronic address:

Background: Continuous passive motion device (CPM) provides repetitive movement over extended periods of time for those who have low functional ability. The purpose of this research was to evaluate the effects of a four-week program of continuous passive motion of the ankle joint on the changes in soleus hypertonia in individuals with cerebral palsy who suffered from life-long hypertonia.

Material And Methods: A single group, repeated-measures study was conducted. Read More

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The association between adult ADHD and food addiction: A mediation analysis.

Appetite 2021 Jul 28:105613. Epub 2021 Jul 28.

Department of Human Sciences, Università Europea di Roma, 00163, Rome, Italy.

Objectives: The aim of this study was to investigate the association between food addiction severity (FA) and ADHD symptomatology. Furthermore, we investigated whether emotional distress, and the mentalization deficits could mediate this relationship.

Methods: Three hundred eighty-five Italian adults (307 women and 78 men) participated in the study and completed the Italian versions of the Modified Yale Food Addiction Scale version 2. Read More

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Changes in sleep structure and sleep spindles are associated with the neuropsychiatric profile in paradoxical insomnia.

Int J Psychophysiol 2021 Jul 28. Epub 2021 Jul 28.

Istanbul University-Cerrahpasa, Cerrahpasa Faculty of Medicine, Department of Neurology, Sleep and Disorders Unit, Istanbul 34098, Turkey.

Aim: Sleep spindles have an important role in the pathophysiology and perception of sleep. We aimed to investigate the link between sleep spindles and microstructural architecture of sleep in regard to psychiatric characteristics in paradoxical insomnia.

Method: A total of 40 participants (20 with paradoxical insomnia, 20 healthy controls) were included in the study. Read More

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Cyclothymic Temperament is Associated with Poor Medication Adherence and Disordered Eating in Type 2 Diabetes Patients: A Case-Control Study.

Diabetes Ther 2021 Jul 31. Epub 2021 Jul 31.

Division of Diabetes, Endocrinology and Metabolism, Department of Medicine, Kimitsu Chuo Hospital, Sakurai 1010, Kisarazu, Chiba, 292-0822, Japan.

Introduction: Poor medication adherence and disordered eating are major self-care problems in patients with type 2 diabetes that worsen glycemic control and increase the risk of developing severe diabetes complications. Affective temperament, which remains mostly unchanged throughout life, is speculated to predict poor treatment response and high comorbidity. The aim of this study was to explore the link between affective temperament and poor glycemic control due to insufficient self-care. Read More

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Psychological impact of COVID-19 on speech and language therapists working with adult dysphagia: A national survey.

Int J Lang Commun Disord 2021 Jul 31. Epub 2021 Jul 31.

Speech and Language Pathology Department of Clinical Speech and Language Studies, Trinity College Dublin, Dublin, Ireland.

Background: Speech and language therapists (SLTs) working with dysphagia have had to radically alter diagnostic and rehabilitation services during the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic, hereafter referred to as coronavirus disease (COVID-19). Given the aerosol-generating procedures inherent in swallow assessment and interventions, these SLTs have also been particularly susceptible to virus exposure.

Aims: To investigate the psychological impact of COVID-19 on SLTs working with adult dysphagia across the Republic of Ireland and to identify the personal and professional factors associated with depression, anxiety, stress and post-traumatic stress disorder (PTSD). Read More

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[Positive effect of bright light therapy on mood and sleep quality in institutionalized older people].

Rev Esp Geriatr Gerontol 2021 Jul 27. Epub 2021 Jul 27.

Universitat de les Illes Balears (UIB). IdisBa, Institut d'Investigació Sanitària Illes Balears, Palma de Mallorca, Illes Balears, España; Departamento de Psiquiatría, Hospital Universitario Son Espases (HUSE). IdisBa, Institut d'Investigació Sanitària Illes Balears, Palma de Mallorca, Illes Balears, España. Electronic address:

Introduction: Bright light exposure during the day has a positive effect on health and its deficit can cause multiple physiological and cognitive disorders, including depression. The aim of this study was to evaluate the effect of bright light therapy (BLT) on the quality of sleep and mood emotional state; cognitive status, global deterioration and quality of life in institutionalized elderly.

Material And Methods: This is a study with repeated measures design. Read More

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Flupentixol/melitracen for chronic refractory cough after treatment failure with other neuromodulators.

Int J Tuberc Lung Dis 2021 Aug;25(8):648-654

Department of Pulmonary and Critical Care Medicine, Tongji Hospital, School of Medicine, Tongji University, Shanghai, China.

Gabapentin and baclofen are recommended for the treatment of chronic refractory cough (CRC). We investigated the efficacy of flupentixol/melitracen in patients unresponsive to these neuromodulators. A total of 101 patients with CRC who failed to respond to gabapentin and baclofen were recruited, and treated with flupentixol/melitracen. Read More

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Testosterone and depressive symptoms during the late menopause transition.

Biol Sex Differ 2021 Jul 30;12(1):44. Epub 2021 Jul 30.

Department of Psychology, University of Regina, Regina, Saskatchewan, Canada.

Background: The menopause transition is associated with an increased risk of depression. While the mechanisms behind this increased risk are not well understood, the changing perimenopausal hormonal environment has been hypothesized to play a role. The current study examined the potential influence of testosterone and the ratio of testosterone to estradiol as a potential contributor to depressed mood in the menopause transition. Read More

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Health-related risky behaviors in Chinese adolescents with autism: a cross-sectional study.

Child Adolesc Psychiatry Ment Health 2021 Jul 30;15(1):39. Epub 2021 Jul 30.

Peking University Institute of Mental Health, Peking University Sixth Hospital, Key Laboratory of Mental Health, National Health Commission (Peking University), National Clinical Research Center for Mental Disorders (Peking University Sixth Hospital), No. 51 Huayuan North Road, Haidian District, Beijing, 100191, China.

Background: Health-related risky behaviors (HRB) generally refer to behaviors that have a negative influence on health and quality of life. HRB in adolescents with autism have not been well understood so far. We aim to explore health-related risky behaviors and their risk factors with autistic adolescents. Read More

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Clinical and genetic factors associated with anxiety and depression in breast cancer patients: a cross-sectional study.

BMC Cancer 2021 Jul 30;21(1):872. Epub 2021 Jul 30.

Faculty of Pharmacy, Saint-Joseph University, Beirut, Lebanon.

Background: Despite the progress in assessment and treatment of breast cancer, being diagnosed with it or receiving chemotherapy treatment is still conceived as a traumatic experience. Women develop negative thoughts about life and death with detrimental effects on their daily physical functioning/activities, emotional state and overall quality of life. The aim of our study was to evaluate the level of anxiety and depression among breast cancer patients receiving chemotherapy and explore the correlation between these psychological disorders, clinical, sociodemographic and genetic factors. Read More

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Duration of untreated illness and bipolar disorder: time for a new definition? Results from a cross-sectional study.

J Affect Disord 2021 Jul 22;294:513-520. Epub 2021 Jul 22.

Bipolar and Depressive Disorders Unit, Institute of Neuroscience, Hospital Clinic, University of Barcelona, IDIBAPS, CIBERSAM, 170 Villarroel st, 12-0, 08036, Barcelona, Catalonia, Spain.

Background: We primarily aimed to explore the associations between duration of untreated illness (DUI), treatment response, and functioning in a cohort of patients with bipolar disorder (BD).

Methods: 261 participants with BD were recruited. DUI was defined as months from the first affective episode to the start of a mood-stabilizer. Read More

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Are we still uncertain about the latent structure of intolerance of uncertainty: Results from factor mixture modeling in a Serbian sample.

J Affect Disord 2021 Jul 22;294:505-512. Epub 2021 Jul 22.

Department of Psychology, University of Novi Sad, Serbia.

Background: Intolerance of uncertainty (IU) is a transdiagnostic risk factor for emotional disorders. Exploring the nature of IU might allow us to understand better a difference between pathological and normal worry processes. For that purpose, factor mixture modeling (FMM) can be used to test the latent structure of IU across a categorical-dimensional spectrum. Read More

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Global topology alteration of the brain functional network affects the 8-week antidepressant response in major depressive disorder.

J Affect Disord 2021 Jul 22;294:491-496. Epub 2021 Jul 22.

Department of Psychosomatics and Psychiatry, School of Medicine, Zhongda Hospital, Southeast University, Nanjing, China. Electronic address:

Purpose: Previous studies have indicated that the global topology of the brain functional network in patients with major depressive disorder (MDD) differs from that of those with normal controls (NCs). However, the relationship between an altered global topology and the response to antidepressants remains unclear. Here, we investigated whether differences in global topology affect the efficacy of antidepressants in MDD patients. Read More

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Association between resilience and cortical thickness in the posterior cingulate cortex and the temporal pole in Japanese older people: A population-based cross-sectional study.

J Psychiatr Res 2021 Jul 20;142:89-100. Epub 2021 Jul 20.

Department of Neuropsychiatry, Keio University School of Medicine, Tokyo, Japan. Electronic address:

Background: Resilience is a crucial factor preventing the onset of mental illness and contributing to the well-being and healthy longevity, whose neural bases are not fully elucidated in older people. The present study aimed to identify the cortical thickness associating with resilience in older adults.

Methods: This is a part of the cross-sectional Arakawa geriatric cohort study for people aged 65 years or older, consisting of 1001 individuals. Read More

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A Longitudinal Study on the Changes in Mental Health of Healthcare Workers during the COVID-19 Pandemic.

Psychiatry 2021 Jul 30:1-16. Epub 2021 Jul 30.

: This study examines Argentinean health care workers in order to 1) test self-perceived job performance levels and the presence of psychological symptoms compatible with common mental disorders, and 2) examine within-person changes in general discomfort and psychological distress, adjusting for demographic factors, region, and health-related factors during two time points of the COVID-19 pandemic.: This longitudinal study comprised 305 healthcare workers who completed a survey at two time points approximately 4 months apart. We used the General Health Questionnaire and the Kessler Psychological Distress Scale to measure mental health outcomes. Read More

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Psychometric properties of the Chinese version of the Courtauld Emotional Control Scale in women newly diagnosed with breast cancer.

Qual Life Res 2021 Jul 30. Epub 2021 Jul 30.

Medical Psychological Center, The Second Xiangya Hospital, Central South University, Renmin Middle Road 139#, Furong District, Changsha, 410011, Hunan, China.

Purpose: Emotional control, the attempt to suppress the expression of negative effects, is an essential factor in the prevalence of psychological distress in women with breast cancer. The Courtauld Emotional Control Scale (CECS) is a commonly used self-report tool for assessing emotional suppression in both clinical and general groups. This study aimed to validate the Chinese version of the Courtauld Emotional Control Scale (CECS) in women newly diagnosed with breast cancer. Read More

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Supporting Patient-Clinician Interaction in Chronic HIV Care: Design and Development of a Patient-Reported Outcomes Software Application.

J Med Internet Res 2021 Jul 30;23(7):e27861. Epub 2021 Jul 30.

Patient-Centered Outcomes Research, Health Economics Clinical Trial Unit, Hospital Hotel-Dieu, AP-HP, University de Paris, Paris, France.

Background: The consideration of health-related quality of life (HRQL) is a hallmark of best practice in HIV care. Information technology offers an opportunity to more closely engage patients with chronic HIV infection in their long-term management and support a focus on HRQL. However, the implementation of patient-reported outcome (PRO) measures, such as HRQL in routine care, is challenged by the need to synthesize data generated by questionnaires, the complexity of collecting data between patient visits, and the integration of results into clinical decision-making processes. Read More

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Psychological outcomes amongst family medicine healthcare professionals during COVID-19 outbreak: A cross-sectional study in Croatia.

Eur J Gen Pract 2021 Dec;27(1):184-190

Private Family Physician Office, Department of Family Medicine, Zagreb University School of Medicine, School of Public Health 'Andrija Štampar', Zagreb, Croatia.

Background: Healthcare professionals (HCPs) in family medicine (FM) in Croatia work in a demanding environment caused by the SARS-CoV-2 pandemic. Besides particular circumstances in healthcare, an unknown virus, social distancing, and homeschooling, the capital was hit with the earthquake during the lockdown.

Objectives: To assess the prevalence of stress, anxiety, depression, posttraumatic stress disorder (PTSD) and the influence of demographic characteristics, professional differences, medical history, and specific stressors on the psychological outcomes. Read More

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December 2021

The psychological impact of the Coronavirus emergency on physicians and nurses: an Italian observational study.

Acta Biomed 2021 Jul 29;92(S2):e2021030. Epub 2021 Jul 29.

"Santa Chiara" Institute, Lecce, Italy.

Background: The Coronavirus has put a strain on the response capacity of health systems and there are various psychological effects on health workers.

Aim Of The Study: To investigate the psychological impact of the coronavirus emergency on physicians and nurses.

Materials And Methods: A study was conducted on a sample of nurses and physicians (n=770), who were asked to fill in a questionnaire investigating physical and psychological problems. Read More

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Prevalence and correlates of hopelessness in Tunisian women with benign breast disease and breast cancer.

J Psychosoc Oncol 2021 Jul 30:1-18. Epub 2021 Jul 30.

Faculty of Medicine of Tunis, Tunis El Manar University, Tunis, Tunisia.

Background: There is limited research suggesting that women with Benign Breast Disease (BBD) experience psychological distress similar to breast cancer (BC) women. We aimed to examine hopelessness and its related factors in BC and BBD women.

Method: This was a cross-sectional study. Read More

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Virtual Group Appointments Reduce Distress and Improve Care Management in Young Adults with Type 1 Diabetes.

J Diabetes Sci Technol 2021 Jul 30:19322968211035768. Epub 2021 Jul 30.

Children's Hospital Los Angeles, Los Angeles, CA, USA.

Purpose: The purpose of this study was to analyze the impact of virtual group appointments (VGA) on self-reported health-related outcomes and care activities for young adults (YA) with type 1 diabetes (T1D).

Methods: Fifty-three YA (ages 18-25 years) with T1D participated in a randomized controlled trial (RCT) of the Colorado Young Adults with T1D (CoYoT1) Clinic intervention, encompassing telehealth (TH) with or without VGA. Both new patients ( = 32) and those who participated in a pilot phase ( = 26) were randomized to CoYoT1 Clinic (TH+VGA;  = 23) or TH-only ( = 35) and followed for 1 year. Read More

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Socio-Demographic and Coping Correlates and Predictors of Depressive Symptoms Among Low-Income and Ethnic Minority Mothers At-Risk.

Clin Nurs Res 2021 Jul 30:10547738211029685. Epub 2021 Jul 30.

Rutgers the State University of New Jersey School of Nursing-Camden, USA.

This study identified coping and sociodemographic correlates and predictors of depressive symptoms in mothers at risk for clinical depression. A descriptive, cross-sectional design was employed. A convenience sample of 88 low-income or ethnic-minority mothers aged 21 to 45 completed a depression scale, demographic data sheet, and responded to an open-ended question. Read More

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[Loneliness during the first wave of the SARS-CoV-2 pandemic-results of the German National Cohort (NAKO)].

Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 2021 Jul 29. Epub 2021 Jul 29.

Zentrum Psychiatrische Rehabilitation, Universitäre Psychiatrische Dienste Bern, Bern, Schweiz.

Background: Early during the pandemic and the following protective countermeasures, an interest in the consequences of the enacted restriction of social contacts for the mental health of the population arose. Loneliness describes the perceived quality of one's own contacts and relationships with other individuals. Several prior studies reported associations of loneliness with different somatic and psychiatric disorders. Read More

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Prevalence and risk factors for repetition of non-fatal self-harm in Hong Kong, 2002-2016: A population-based cohort study.

Lancet Reg Health West Pac 2020 Sep 12;2:100027. Epub 2020 Sep 12.

Department of Social Work and Social Administration, Centre for Suicide Research and Prevention, The University of Hong Kong, Hong Kong, China.

Background: A history of self-harm is strongly associated with future self-harm attempts. Large-scale Asian cohort studies examining risk factors for repeated self-harm are lacking. This paper reports on annual prevalence, cumulative risk, annual risk of non-fatal self-harm repetition, and risk factors among Hong Kong patients with a history of self-harm. Read More

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September 2020

Role of perceived family support in psychological distress for pregnant women during the COVID-19 pandemic.

World J Psychiatry 2021 Jul 19;11(7):365-374. Epub 2021 Jul 19.

CAS Key Laboratory of Mental Health, Institute of Psychology, Chinese Academy of Sciences, Beijing 100101, China.

Background: The coronavirus disease 2019 (COVID-19) pandemic has caused major public panic in China. Pregnant women may be more vulnerable to stress, which may cause them to have psychological problems.

Aim: To explore the effects of perceived family support on psychological distress in pregnant women during the COVID-19 pandemic. Read More

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