277 results match your criteria dependencies varied


To pool or not to pool: That is the question in microbial kinetics.

Int J Food Microbiol 2021 Jun 7:109283. Epub 2021 Jun 7.

Food Quality & Design Group, Wageningen University & Research, the Netherlands. Electronic address:

Variation observed in heat inactivation of Salmonella strains (data from Combase) was characterized using multilevel modeling with two case studies. One study concerned repetitions at one temperature, the other concerned isothermal experiments at various temperatures. Multilevel models characterize variation at various levels and handle dependencies in the data. Read More

View Article and Full-Text PDF

Challenges in accessing routinely collected data from multiple providers in the UK for primary studies: Managing the morass.

Int J Popul Data Sci 2018 Sep 21;3(3):432. Epub 2018 Sep 21.

Centre for Trials Research, Cardiff University, Neuadd Meirionnydd, Heath Park Way, Cardiff CF14 4YS.

Introduction: Researchers are increasingly using routinely collected data in addition to, or instead of, other data collection methods. The UK government continues to invest in research centres to encourage use of these data, and trials and cohort studies utilise data linkage methods in the follow-up of participants. This does not come without its limitations and challenges, such as data access delays. Read More

View Article and Full-Text PDF
September 2018

Quantifying the demographic vulnerabilities of dry woodlands to climate and competition using range-wide monitoring data.

Ecology 2021 Jun 5:e03425. Epub 2021 Jun 5.

U.S. Geological Survey, Southwest Biological Science Center, Flagstaff, Arizona, 86001, USA.

Climate change is expected to alter the distribution and abundance of tree species, impacting ecosystem structure and function. Yet, anticipating where this will occur is often hampered by a lack of understanding of how demographic rates, most notably recruitment, vary in response to climate and competition across a species range. Using large-scale monitoring data on two dry woodland tree species (Pinus edulis and Juniperus osteosperma), we develop an approach to infer recruitment, survival, and growth of both species across their range. Read More

View Article and Full-Text PDF

Matched Filter Cyclone Maximum Wind Retrievals Using CYGNSS: Progress Update and Error Analysis.

IEEE J Sel Top Appl Earth Obs Remote Sens 2021 17;14:3591-3601. Epub 2021 Mar 17.

Constellation Observing System for Meteorology, Ionosphere, and Climate Program, University Corporation for Atmospheric Research, Boulder, CO 80301 USA.

This article describes progress relating to a previously reported matched filter retrieval approach for the estimation of hurricane maximum winds using delay Doppler map (DDM) measurements of the Cyclone Global Navigation Satellite System (CYGNSS) mission. The retrievals presented are based on comparisons of these measured DDMs, and their simulated counterparts as a set of storm parameters are varied. The analysis presented examines the dependencies of retrieval performance on the synthetic storm model used as part of the forward modeling process using a set of CYGNSS storm-observing full DDM downlinks containing 68 tracks and spanning 18 storms over the period 2017-2020. Read More

View Article and Full-Text PDF

Pore-scale modelling and sensitivity analyses of hydrogen-brine multiphase flow in geological porous media.

Sci Rep 2021 Apr 16;11(1):8348. Epub 2021 Apr 16.

Faculty of Civil Engineering and Geosciences, Delft University of Technology, P.O. Box 5048, 2600 GA, Delft, The Netherlands.

Underground hydrogen storage (UHS) in initially brine-saturated deep porous rocks is a promising large-scale energy storage technology, due to hydrogen's high specific energy capacity and the high volumetric capacity of aquifers. Appropriate selection of a feasible and safe storage site vitally depends on understanding hydrogen transport characteristics in the subsurface. Unfortunately there exist no robust experimental analyses in the literature to properly characterise this complex process. Read More

View Article and Full-Text PDF

Occupational position and alcohol use disorders in Poland.

Int J Occup Med Environ Health 2021 Apr 6. Epub 2021 Apr 6.

Institute of Psychiatry and Neurology, Warsaw, Poland (Department of Studies on Alcoholism and Drug Dependencies).

Objectives: The following analysis covers the role of the occupational structure in the prevalence of alcohol use disorders (AUDs). The authors investigated whether the occupational position affected the prevalence of AUDs among men and women, and how this relationship varied in lifetime and past year periods.

Material And Methods: Data were taken from the General Population Survey on Mental Health in Poland (EZOP) utilizing the questionnaire (N = 2806). Read More

View Article and Full-Text PDF

COVID-19 policy analysis: labour structure dictates lockdown mobility behaviour.

J R Soc Interface 2021 03 31;18(176):20201035. Epub 2021 Mar 31.

The Bartlett Centre for Advanced Spatial Analysis, University College London, London W1 4TJ, UK.

Countries and cities around the world have resorted to unprecedented mobility restrictions to combat COVID-19 transmission. Here we exploit a natural experiment whereby Colombian cities implemented varied lockdown policies based on ID number and gender to analyse the impact of these policies on urban mobility. Using mobile phone data, we find that the restrictiveness of cities' mobility quotas (the share of residents allowed out daily according to policy advice) does not correlate with mobility reduction. Read More

View Article and Full-Text PDF

Tmc Reliance Is Biased by the Hair Cell Subtype and Position Within the Ear.

Front Cell Dev Biol 2020 7;8:570486. Epub 2021 Jan 7.

Department of Otolaryngology-Head and Neck Surgery, School of Medicine, Case Western Reserve University, Cleveland, OH, United States.

Hair cells are heterogenous, enabling varied roles in sensory systems. An emerging hypothesis is that the transmembrane channel-like (Tmc) proteins of the hair cell's mechanotransduction apparatus vary within and between organs to permit encoding of different mechanical stimuli. Five anatomical variables that may coincide with different Tmc use by a hair cell within the ear are the containing organ, cell morphology, cell position within an organ, axis of best sensitivity for the cell, and the hair bundle's orientation within this axis. Read More

View Article and Full-Text PDF
January 2021

The effect of decay and lexical uncertainty on processing long-distance dependencies in reading.

PeerJ 2020 17;8:e10438. Epub 2020 Dec 17.

Department of Linguistics, Universität Potsdam, Potsdam, Germany.

To make sense of a sentence, a reader must keep track of dependent relationships between words, such as between a verb and its particle (e.g. the music ). Read More

View Article and Full-Text PDF
December 2020

Methods to measure effects of social accountability interventions in reproductive, maternal, newborn, child, and adolescent health programs: systematic review and critique.

J Health Popul Nutr 2020 12 7;39(1):13. Epub 2020 Dec 7.

UNDP/UNFPA/UNICEF/WHO/World Bank Special Programme of Research, Development and Research Training in Human Reproduction (HRP Research), World Health Organization, Geneva, Switzerland.

Background: There is no agreed way to measure the effects of social accountability interventions. Studies to examine whether and how social accountability and collective action processes contribute to better health and healthcare services are underway in different areas of health, and health effects are captured using a range of different research designs.

Objectives: The objective of our review is to help inform evaluation efforts by identifying, summarizing, and critically appraising study designs used to assess and measure social accountability interventions' effects on health, including data collection methods and outcome measures. Read More

View Article and Full-Text PDF
December 2020

Impact of concatenating fMRI data on reliability for functional connectomics.

Neuroimage 2021 02 26;226:117549. Epub 2020 Nov 26.

The Child Mind Institute, 101 East 56th Street, New York, NY 10022, United States. Electronic address:

Compelling evidence suggests the need for more data per individual to reliably map the functional organization of the human connectome. As the notion that 'more data is better' emerges as a golden rule for functional connectomics, researchers find themselves grappling with the challenges of how to obtain the desired amounts of data per participant in a practical manner, particularly for retrospective data aggregation. Increasingly, the aggregation of data across all fMRI scans available for an individual is being viewed as a solution, regardless of scan condition (e. Read More

View Article and Full-Text PDF
February 2021

Standardization of T1-mapping in cardiovascular magnetic resonance using clustered structuring for benchmarking normal ranges.

Int J Cardiol 2021 03 21;326:220-225. Epub 2020 Oct 21.

Oxford Centre for Clinical Magnetic Resonance Research (OCMR), Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom.

Background: Cardiovascular magnetic resonance T1-mapping is increasingly used for tissue characterization, commonly based on Modified Look-Locker Inversion recovery (MOLLI). However, there are numerous MOLLI variants with differing normal ranges. This lack of standardization presents confusion and difficulty in inter-center comparisons, hindering widespread adoption of T1-mapping. Read More

View Article and Full-Text PDF

Paris car parking problem for partially oriented discorectangles on a line.

Phys Rev E 2020 Jul;102(1-1):012128

Laboratory of Mathematical Modeling, Astrakhan State University, Astrakhan 414056, Russia.

The random sequential adsorption (RSA) of identical elongated particles (discorectangles) on a line ("Paris car parking problem") was studied numerically. An off-lattice model with continuous positional and orientational degrees of freedom was considered. The possible orientations of the discorectanles were restricted between θ∈[-θ_{m};θ_{m}] while the aspect ratio (length-to-width ratio) for the discorectangles was varied within the range ɛ∈[1;100]. Read More

View Article and Full-Text PDF

Assessment of RBE-Weighted Dose Models for Carbon Ion Therapy Toward Modernization of Clinical Practice at HIT: In Vitro, in Vivo, and in Patients.

Int J Radiat Oncol Biol Phys 2020 11 3;108(3):779-791. Epub 2020 Jun 3.

Clinical Cooperation Unit Translational Radiation Oncology, National Center for Tumor Diseases, Heidelberg University Hospital and German Cancer Research Center, Heidelberg, Germany; National Centre of Oncological Hadrontherapy, Medical Physics, Pavia, Italy; Heidelberg Ion-Beam Therapy Center, Department of Radiation Oncology, Heidelberg University Hospital, Heidelberg, Germany. Electronic address:

Purpose: Present-day treatment planning in carbon ion therapy is conducted with assumptions for a limited number of tissue types and models for effective dose. Here, we comprehensively assess relative biological effectiveness (RBE) in carbon ion therapy and associated models toward the modernization of current clinical practice in effective dose calculation.

Methods: Using 2 human (A549, H460) and 2 mouse (B16, Renca) tumor cell lines, clonogenic cell survival assay was performed for examination of changes in RBE along the full range of clinical-like spread-out Bragg peak (SOBP) fields. Read More

View Article and Full-Text PDF
November 2020

Soft X-ray diffraction patterns measured by a LiF detector with sub-micrometre resolution and an ultimate dynamic range.

J Synchrotron Radiat 2020 May 16;27(Pt 3):625-632. Epub 2020 Mar 16.

Moscow Engineering Physics Institute (MEPhI), Kashirskoe shosse 31, Moscow 115409, Russian Federation.

The unique diagnostic possibilities of X-ray diffraction, small X-ray scattering and phase-contrast imaging techniques applied with high-intensity coherent X-ray synchrotron and X-ray free-electron laser radiation can only be fully realized if a sufficient dynamic range and/or spatial resolution of the detector is available. In this work, it is demonstrated that the use of lithium fluoride (LiF) as a photoluminescence (PL) imaging detector allows measuring of an X-ray diffraction image with a dynamic range of ∼10 within the sub-micrometre spatial resolution. At the PETRA III facility, the diffraction pattern created behind a circular aperture with a diameter of 5 µm irradiated by a beam with a photon energy of 500 eV was recorded on a LiF crystal. Read More

View Article and Full-Text PDF

The Predictive Value of Tagalog Voice Morphology in Filler-Gap Dependency Formation.

Front Psychol 2020 15;11:517. Epub 2020 Apr 15.

Department of Linguistics, University of California, Santa Cruz, Santa Cruz, CA, United States.

Research has shown that when processing filler-gap dependencies, comprehenders do not wait until they encounter all of the bottom-up information in the input. Instead, they use various types of linguistic information to predictively posit a gap that would allow the dependency to be resolved. They can use syntactic (Traxler and Pickering, 1996), lexical (Trueswell et al. Read More

View Article and Full-Text PDF

Effect of Small Focus on Electron Heating and Proton Acceleration in Ultrarelativistic Laser-Solid Interactions.

Phys Rev Lett 2020 Feb;124(8):084802

Kansai Photon Science Institute, National Institutes for Quantum and Radiological Science and Technology, Kizugawa, Kyoto 619-0215, Japan.

Acceleration of particles from the interaction of ultraintense laser pulses up to 5×10^{21}  W cm^{-2} with thin foils is investigated experimentally. The electron beam parameters varied with decreasing spot size, not just laser intensity, resulting in reduced temperatures and divergence. In particular, the temperature saturated due to insufficient acceleration length in the tightly focused spot. Read More

View Article and Full-Text PDF
February 2020

Two-dimensional profile of the region of distractors' influence on visual length judgments.

Atten Percept Psychophys 2020 Jul;82(5):2714-2727

Institute of Biological Systems and Genetics Research, Lithuanian University of Health Sciences, Mickevičiaus 9, LT-44307, Kaunas, Lithuania.

In the illusion of interrupted spatial extent (also known as the filled-space or Oppel-Kundt illusion), the stimulus spatial interval filled with some visual elements (distractors) appears larger than the unfilled interval of the same size. Despite a long history of research, there is still no consensus on the origin of this visual phenomenon. It was recently shown (Bulatov, Bulatova, Surkys, & Mickienė, Acta Neurobiologiae Experimentalis, 77, 157-167, 2017) that the illusion emergence can be associated mainly with the integration of distractor-evoked effects in regions surrounding the endpoints (terminators) of the stimulus intervals. Read More

View Article and Full-Text PDF

Impact of seasonality, redox conditions, travel distances and initial concentrations on micropollutant removal during riverbank filtration at four sites.

Chemosphere 2020 Jul 17;250:126255. Epub 2020 Feb 17.

Institute of Geology and Palaeontology - Applied Geology, University of Münster, Corrensstraße 24, 48149, Münster, Germany. Electronic address:

Riverbank filtration (RBF) is a reliable water purification technique that has proven to be suitable for the removal of organic micropollutants. Its removal efficiency and dependency on a variety of factors such as redox conditions, temperatures, geology, travel times, level of initial micropollutant concentrations and seasonality were investigated during three seasonal sampling campaigns. Two anoxic (silty sand, Ems river) and two oxic (gravel, Ruhr river) RBF sites in Germany with different travel distances (42-633 m) were studied. Read More

View Article and Full-Text PDF

Characterization of microMOSFET detectors for in vivo dosimetry in high-dose-rate brachytherapy with Ir.

Med Phys 2020 Jun 18;47(5):2242-2253. Epub 2020 Mar 18.

Instituto de Investigación Biosanitaria (ibs.GRANADA), Hospital Clínico Universitario San Cecilio, Unidad de Radiofísica, Granada, Spain.

Purpose: The objective of this study was to characterize the Best Medical Canada microMOSFET detectors for their application in in vivo dosimetry for high-dose-rate brachytherapy (HDRBT) with Ir. We also developed a mathematical model to correct dependencies under the measurement conditions of these detectors.

Methods: We analyzed the linearity, reproducibility, and interdetector variability and studied the microMOSFET response dependence on temperature, source-detector distance, and angular orientation of the receptor with respect to the source. Read More

View Article and Full-Text PDF

Identification of functional regulatory elements in the human genome using pooled CRISPR screens.

BMC Genomics 2020 Jan 31;21(1):107. Epub 2020 Jan 31.

Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA.

Background: Genome-scale pooled CRISPR screens are powerful tools for identifying genetic dependencies across varied cellular processes. The vast majority of CRISPR screens reported to date have focused exclusively on the perturbation of protein-coding gene function. However, protein-coding genes comprise < 2% of the sequence space in the human genome leaving a substantial portion of the genome uninterrogated. Read More

View Article and Full-Text PDF
January 2020

Reading the geography of India's district-level fertility differentials: a spatial econometric approach.

J Biosoc Sci 2019 09;51(5):745-774

3Department of Geography,Presidency University,Kolkata,India.

India has gradually progressed into fertility transition over the last few decades. However, the timing and pace of this transition has varied notably in terms of both its geography and the demographic groups most affected by it. While much literature exists on the relationships between fertility level and its influence on demographic, economic, socio-cultural and policy-related factors, the potential spatial variations in the effects of these factors on the fertility level remain unaddressed. Read More

View Article and Full-Text PDF
September 2019

Mapping Ethnic Stereotypes and Their Antecedents in Russia: The Stereotype Content Model.

Front Psychol 2019 16;10:1643. Epub 2019 Jul 16.

National Research University Higher School of Economics, Moscow, Russia.

The stereotype content model (SCM), originating in the United States and generalized across nearly 50 countries, has yet to address ethnic relations in one of the world's most influential nations. Russia and the United States are somewhat alike (large, powerful, immigrant-receiving), but differ in other ways relevant to intergroup images (culture, religions, ideology, and history). Russian ethnic stereotypes are understudied, but significant for theoretical breadth and practical politics. Read More

View Article and Full-Text PDF

Dynamic, data-driven typologies of long-term smoking, cessation, and their correlates: Findings from the International Tobacco Control (ITC) Netherlands Survey.

Soc Sci Med 2019 08 4;235:112393. Epub 2019 Jul 4.

Department of Health Promotion, CAPHRI Care and Public Health Research Institute, Maastricht University, P.O. Box 616, 6200, MD, Maastricht, the Netherlands. Electronic address:

Rationale: Efforts towards tobacco control are numerous, but relapse rates for smoking cessations remain high. Behavioral changes necessary for continuous cessation appear complex, variable and subject to social, biological, psychological and environmental determinants. Currently, most cessation studies concentrate on short-to midterm behavioral changes. Read More

View Article and Full-Text PDF

Space, Time, and Size Dependencies of Greenhouse Gas Payback Times of Wind Turbines in Northwestern Europe.

Environ Sci Technol 2019 Aug 26;53(15):9289-9297. Epub 2019 Jul 26.

Department of Environmental Science, Faculty of Sciences , Radboud University Nijmegen , Heyendaalseweg 135 , 6525 AJ Nijmegen , The Netherlands.

The net greenhouse gas benefits of wind turbines compared to their fossil energy counterparts depend on location-specific wind climatology and the turbines' technological characteristics. Assessing the environmental impact of individual wind parks requires a universal but location-dependent method. Here, the greenhouse gas payback time for 4161 wind turbine locations in northwestern Europe was determined as a function of (i) turbine size and (ii) spatial and temporal variability in wind speed. Read More

View Article and Full-Text PDF

A realist review of which advocacy interventions work for which abused women under what circumstances.

Cochrane Database Syst Rev 2019 06 29;6:CD013135. Epub 2019 Jun 29.

Department of Social Science, UCL Institute of Education, University College London, 18 Woburn Square, London, UK, WC1H 0NR.

Background: Intimate partner abuse (including coercive control, physical, sexual, economic, emotional and economic abuse) is common worldwide. Advocacy may help women who are in, or have left, an abusive intimate relationship, to stop or reduce repeat victimisation and overcome consequences of the abuse. Advocacy primarily involves education, safety planning support and increasing access to different services. Read More

View Article and Full-Text PDF

Cortical Auditory Evoked Potentials in Response to Frequency Changes with Varied Magnitude, Rate, and Direction.

J Assoc Res Otolaryngol 2019 10 5;20(5):489-498. Epub 2019 Jun 5.

Department of Otorhinolaryngology and Head & Neck Surgery, University Medical Center Utrecht, Room G.02.531, P.O. Box 85500, 3508 GA, Utrecht, The Netherlands.

Recent literature on cortical auditory evoked potentials has focused on correlations with hearing performance with the aim to develop an objective clinical tool. However, cortical responses depend on the type of stimulus and choice of stimulus parameters. This study investigates cortical auditory evoked potentials to sound changes, so-called acoustic change complexes (ACC), and the effects of varying three stimulus parameters. Read More

View Article and Full-Text PDF
October 2019

An Evolutionary Model-Based Approach To Quantify the Genetic Barrier to Drug Resistance in Fast-Evolving Viruses and Its Application to HIV-1 Subtypes and Integrase Inhibitors.

Antimicrob Agents Chemother 2019 08 25;63(8). Epub 2019 Jul 25.

Global Health and Tropical Medicine, Instituto de Higiene e Medicina Tropical, Universidade Nova de Lisboa, Lisbon, Portugal.

Viral pathogens causing global disease burdens are often characterized by high rates of evolutionary changes. The extensive viral diversity at baseline can shorten the time to escape from therapeutic or immune selective pressure and alter mutational pathways. The impact of genotypic background on the barrier to resistance can be difficult to capture, particularly for agents in experimental stages or that are recently approved or expanded into new patient populations. Read More

View Article and Full-Text PDF

EEG Microstates Temporal Dynamics Differentiate Individuals with Mood and Anxiety Disorders From Healthy Subjects.

Front Hum Neurosci 2019 26;13:56. Epub 2019 Feb 26.

Laureate Institute for Brain Research, Tulsa, OK, United States.

Electroencephalography (EEG) measures the brain's electrophysiological spatio-temporal activities with high temporal resolution. Multichannel and broadband analysis of EEG signals is referred to as EEG microstates (EEG-ms) and can characterize such dynamic neuronal activity. EEG-ms have gained much attention due to the increasing evidence of their association with mental activities and large-scale brain networks identified by functional magnetic resonance imaging (fMRI). Read More

View Article and Full-Text PDF
February 2019

Water depth-dependent notonectid predatory impacts across larval mosquito ontogeny.

Pest Manag Sci 2019 Oct 13;75(10):2610-2617. Epub 2019 Mar 13.

Department of Ecology and Environmental Science, Assam University, Silchar, India.

Background: Context-dependencies can modulate the strength of predatory interactions and often remain unquantified. In particular, differences in water depth within aquatic systems could influence predator efficiencies towards prey which utilise three-dimensional space through the water column. Differences in prey size could drive prey size-refuge effects, influencing the efficacy of natural enemies towards vector species. Read More

View Article and Full-Text PDF
October 2019