7,300 results match your criteria dentifrices


Ultrasonic measurement of dentin remineralization effects of dentifrices and silver diamine fluoride.

Acta Odontol Scand 2021 Apr 6:1-8. Epub 2021 Apr 6.

Department of Operative Dentistry, Nihon University School of Dentistry, Tokyo, Japan.

Objective: This study investigated the dentin remineralization effect of the application of a functionalized tri-calcium phosphate (fTCP) dentifrice and a silver diamine fluoride (SDF) solution.

Material And Methods: The materials used were: a fluoride-containing dentifrice with fTCP (fTCP+), a fluoride-containing dentifrice without fTCP (fTCP-) and a 38% SDF solution. Following treatment, the dentin slabs were immersed in a 0. Read More

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Effect of dentifrice slurry abrasivity and erosive challenge on simulated non-carious cervical lesions development in vitro.

J Oral Sci 2021 ;63(2):191-194

Department of Cariology, Operative Dentistry, and Dental Public Health, School of Dentistry, Indiana University, Oral Health Research Institute.

Purpose: To investigate the effect of slurry abrasive levels and acidic challenges on the development of non-carious cervical lesions.

Methods: Ninety-six extracted upper premolars were affixed in pairs to acrylic blocks and had their root surfaces covered by acrylic resin except for 2 mm from the cemento-enamel junction. The specimens were distributed into six groups (n = 8 pairs) based on two experimental factors: (1) slurry abrasivity level [low/medium/high] and (2) citric acid challenge [yes/no]. Read More

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Investigation of oral malodor prevention by dentifrices as measured by VSC reduction.

J Breath Res 2021 Mar 25. Epub 2021 Mar 25.

Procter and Gamble Co, 8700 Mason-Montgomery Road, Mason, Ohio, 45040, UNITED STATES.

The oral malodor reduction efficacy of dentifrices containing stannous fluoride (SnF2) or zinc plus arginine (Zn/Arg) was evaluated using a halimeter to measure volatile sulfur compounds (VSCs) in two randomized, controlled, single-blind, cross-over pilot clinical trials. Study 1 (N=16) had five 1100 ppm F dentifrices and five treatment periods: Negative Control (NC): 0.243% sodium fluoride (NaF); SnF2 A: 0. Read More

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Rapid Antigingivitis Efficacy of a Novel Stannous Fluoride Dentrifice: Results from a 12-Week Randomized Controlled Clinical Trial.

Compend Contin Educ Dent 2021 Feb;42(2):e5-e9

Principal Investigator, Silverstone Research Group, Las Vegas, Nevada.

Objective: To assess the anti-gingivitis and anti-plaque efficacy of a novel bioavailable stannous fluoride (SnF2) dentifrice to a negative control.

Methods: This was a 12-week randomized, controlled, double-blind, two-treatment, parallel group clinical study. One hundred generally healthy adults with evidence of plaque and gingivitis were enrolled into the study. Read More

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February 2021

Efficacy of an Experimental Occlusion Technology Toothpaste in the Relief of Dentinal Hypersensitivity: An 8-week Randomised Controlled Trial.

Oral Health Prev Dent 2021 Jan;19(1):195-202

Purpose: A novel anhydrous toothpaste formulation has been developed containing the anti-dentinal hypersensitivity (DH) ingredient stannous fluoride (SnF2).

Materials And Methods: This randomised, controlled, examiner-blind, parallel-group, stratified (by baseline Schiff sensitivity score) study compared efficacy of an experimental 'Test' toothpaste (n = 67) containing 0.454% SnF2, 0. Read More

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January 2021

Nocturnal Salivary Fluoride Bioavailability After Brushing with a High-fluoride Dentifrice.

Biol Trace Elem Res 2021 Mar 5. Epub 2021 Mar 5.

Department of Restorative Dentistry, Federal University of Piaui, Campus Universitário Ministro Petrônio Portella - SG 10, Bairro Ininga, Teresina, Piauí, CEP: 64049-550, Brazil.

The use of fluoridated dentifrices is recognized as the main reason for the decline of dental caries and its effect is associated with the bioavailability of fluoride (F) in the oral cavity. High-fluoride dentifrice has been indicated for patients at high risk of caries and management of root lesions. This study aimed to evaluate the bioavailability of F in saliva after the use of high-fluoride dentifrice during the nocturnal period. Read More

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Droplet Sizes Emitted from Demonstration Electric Toothbrushes.

Int J Environ Res Public Health 2021 02 26;18(5). Epub 2021 Feb 26.

Research & Development, Procter & Gamble Service GmbH, German Innovation Center, Frankfurter Straße 145, 61476 Kronberg, Germany.

The COVID-19 pandemic has drawn attention to microbial transmission risk via aerosols in dental practice. Demonstration electric toothbrushes are used intra-orally for education. The aim of this investigation was to measure the size of droplets emitted by the brush head of two demonstration oscillating-rotating electric toothbrushes. Read More

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February 2021

In vitro efficacy of commercial and experimental proteolytic enzyme-based whitening dentifrices on enamel whitening and superficial roughness.

J Esthet Restor Dent 2020 Dec 5. Epub 2020 Dec 5.

Graduate Program in Dentistry, School of Dentistry, Federal University of Pelotas, Pelotas, Rio Grande do Sul, Brazil.

Objective: To evaluate the whiteness index (W ) and surface roughness (Ra) of bovine enamel after simulated tooth brushing with different commercial and experimental whitening dentifrices.

Materials And Methods: Cylindrical enamel bovine specimens were acid etched, stained, and divided in nine groups (n = 8): Colgate® Optic White®, Crest® Baking Soda and Peroxide, Arm and Hammer® Advanced White™ Extreme Whitening, Rembrandt® Deeply White® + Peroxide, Close up® White Attraction Natural Glow, Hinode Prowhite, and experimental dentifrice containing papain (PP), bromelain (PB), or papain and bromelain (PPB). Ra and W were obtained initially and after 600, 1200, and 3,600 cycles of simulated tooth brushing. Read More

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December 2020

Toxicity and effect of whitening toothpastes on enamel surface.

Braz Oral Res 2021 12;35:e025. Epub 2021 Feb 12.

University of Florida , College of Dentistry , Department of Restorative Dental Sciences , Gainesville , FL , USA .

This in vitro study evaluated the biocompatibility and abrasivity of whitening and conventional toothpastes. Samples of conventional (non-whitening) - Edel White Infant (EWI) - and whitening toothpastes - Edel White Whitening (EWW), Edel White CAREFORTE (EWC), Colgate Total 12 Ò Professional (C), and Oral-B Whitening (OB) - were dissolved in culture medium (0.2 g sample weight per mL). Read More

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February 2021

Randomised study of intra-oral kinetics of fluoride-containing toothpastes.

J Dent 2021 Mar 27;106:103587. Epub 2021 Jan 27.

Intertek Clinical Research Services, Ellesmere Port, Cheshire, United Kingdom. Electronic address:

Objectives: This randomised, controlled, analyst blind, crossover study aimed to evaluate and compare salivary fluoride and calcium ion concentration over 60 min following brushing with an assigned treatment and following an orange juice (OJ) or deionised (DI) water rinse 60 min post-brushing.

Methods: Study treatments, both containing 1150 ppm fluoride as NaF and 5% w/w KNO, were the Test (including 1.2 % w/w cocamidopropyl betaine) and Comparator (including tetrasodium pyrophosphate and sodium lauryl sulphate) toothpastes. Read More

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Preventive effect of subacidic 1% NaF-HF gel on dental caries in 6- to 7-year-old schoolchildren: a randomized controlled trial.

Quintessence Int 2021 ;0(0):318-326

Objective: This study aimed to examine and compare the anti-caries effects of slightly acidic 1% NaF-HF gel when applied once or twice (7-day or 6-month interval) to mandibular first molars in 6- to 7-year-old children. Method and materials: This was a 1-year, multi-arm, placebo-controlled, double-blind, parallel-group randomized trial. In total, 1,077 schoolchildren from eight primary schools were allocated to one of the four study groups (group 1, single application; group 2, two applications with a 7-day interval; group 3, two applications with a 6-month interval; group 4, placebo control). Read More

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January 2021

Toothpastes with Enzymes Support Gum Health and Reduce Plaque Formation.

Int J Environ Res Public Health 2021 01 19;18(2). Epub 2021 Jan 19.

Clinic of Conservative and Preventive Dentistry, Center of Dental Medicine, University of Zurich, Plattenstrasse 11, 8032 Zurich, Switzerland.

Enzymes in toothpastes can support host immune responses, and thus maintain oral health. This study aimed to investigate gingival health and the plaque-reducing effects of enzyme-containing toothpastes. A laboratory study tested the antimicrobial potential of different enzyme-containing toothpaste formulations. Read More

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January 2021

Evaluation of Antimicrobial Effect of Air-Polishing Treatments and Their Influence on Human Dental Pulp Stem Cells Seeded on Titanium Disks.

Int J Mol Sci 2021 Jan 16;22(2). Epub 2021 Jan 16.

Department of Surgery, Medicine, Dentistry and Morphological Sciences with Interest in Transplant, Oncology and Regenerative Medicine, University of Modena and Reggio Emilia, 41125 Modena, Italy.

Dental implants are one of the most frequently used treatment options for tooth replacement, and titanium is the metal of choice due to its demonstrated superiority in resisting corrosion, lack of allergic reactions and mechanical strength. Surface roughness of titanium implants favors the osseointegration process; nevertheless, its topography may provide a suitable substrate for bacterial biofilm deposition, causing peri-implantitis and leading to implant failure. Subgingival prophylaxis treatments with cleansing powders aimed to remove the bacterial accumulation are under investigation. Read More

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January 2021

Knowledge and Skills Level on Oral Health Among Students at the "Ferdinand I" Military Technical Academy in Bucharest.

J Med Life 2020 Oct-Dec;13(4):562-567

Titu Maiorescu University, Bucharest, Romania.

The increase in the number of clinical cases with varying levels of damage to dental structures among young adults due to caries and excessive consumption of sweets and acidic beverages leads to questions about why there is an increase of cases despite all means of information. Is there a lack of interest in oral health among young adults? The aim of this study was to evaluate the knowledge and skills level of the students regarding oral health in order to conceive and implement an oral health educational program adapted to their needs and interests. The survey method using a questionnaire was administered to students in the first, second, and third academic year at the "Ferdinand I" Military Technical Academy (Bucharest, Romania) in March 2019 and included general data and specific information about oral health. Read More

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January 2021

In vitro three-dimensional organotypic culture models of the oral mucosa.

In Vitro Cell Dev Biol Anim 2021 Feb 14;57(2):148-159. Epub 2021 Jan 14.

LION Corporation, Odawara, Kanagawa, Japan.

Three-dimensional, organotypic models of the oral mucosa have been developed to study a wide variety of phenomena occurring in the oral cavity. Although a number of models have been developed in academic research labs, only a few models have been commercialized. Models from academic groups offer a broader range of phenotypes while the commercial models are more focused on the oral and gingival mucosa. Read More

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February 2021

Evaluation of the remineralisation potential of bioactive glass, nanohydroxyapatite and casein phosphopeptide-amorphous calcium phosphate fluoride-based toothpastes on enamel erosion lesion -An study.

Indian J Dent Res 2020 Sep-Oct;31(5):670-677

Department of Conservative Dentistry and Endodontics, JSS Dental College and Hospital, JSS Academy of Higher Education and Research, JSS Medical Institutions Campus, Sri Shivarathreeshwara Nagar, Mysuru, Karnataka, India.

Background: Erosion, a dynamic process with periods of demineralisation and remineralisation, has become a common problem in modern societies, owing to changes in life style and dietary habits. Although fluorides have been included in toothpastes that claim to prevent demineralisation and aid remineralisation, their ability to remineralise is limited by low concentration of calcium and phosphate ions available in saliva. Hence, a new paste based on casein phosphopeptide-amorphous calcium phosphate fluoride (CPP-ACPF), nanohydroxyapatite and bioactive glass (BAG) were introduced. Read More

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January 2021

Supragingival Biofilm: Toothpaste and Toothbrushes.

Monogr Oral Sci 2021 21;29:65-73. Epub 2020 Dec 21.

School of Dental Medicine, University of Bern, Bern, Switzerland.

The formation of a physiological biofilm cannot be avoided under normal circumstances. However, the consequences of a supragingivally located biofilm, such as caries, gingivitis and, as a further effect, periodontitis, are relatively easy to avoid. The simplest and most common method used worldwide for the elimination of biofilm is periodic mechanical removal using a toothbrush or similar tools, such as chewing sticks or woods. Read More

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January 2021

Bioavailable fluoride in calcium-containing dentifrices.

Sci Rep 2021 Jan 8;11(1):146. Epub 2021 Jan 8.

Centre for Oral Health Research, Melbourne Dental School, Bio21 Institute, The University of Melbourne, 720 Swanston Street, Carlton, Melbourne, VIC, 3010, Australia.

Calcium added to dentifrices can complex with fluoride ions to reduce intra-oral bioavailability and therefore efficacy in preventing dental caries. Six commercially available dentifrices containing different types of calcium and fluoride were analyzed for total and bioavailable fluoride levels by adding 10 g of dentifrice to 30 mL of distilled deionized water and mixing vigorously for 1 min to simulate toothbrushing. One milliliter of the dentifrice/water slurry was immediately centrifuged and the supernatant removed for bioavailable fluoride analysis and the mixed slurry prior to centrifugation used for total fluoride analysis using a modified microdiffusion method. Read More

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January 2021

Bioavailable gluconate chelated stannous fluoride toothpaste meta-analyses: Effects on dentine hypersensitivity and enamel erosion.

J Dent 2021 Feb 28;105:103566. Epub 2020 Dec 28.

Periodontology, Bristol Dental School, University of Bristol, Lower Maudlin Street, Bristol, BS1 2LY, UK. Electronic address:

Objectives: To compare the effect of bioavailable gluconate-chelated stannous fluoride (SnF) toothpaste with control toothpastes for treatment of dentine hypersensitivity (DH) and enamel erosion.

Data And Sources: A Procter & Gamble Oral Care archive of clinical studies was reviewed from 2000 to 2020. Eligible studies were Randomised Controlled Trials (RCTs) investigating bioavailable gluconate-chelated SnF toothpaste efficacy compared to controls in adult participants measured following tactile (Yeaple force) and/or evaporative stimuli (Schiff score) in-vivo, duration <2 months (DH); or by erosive toothwear (profilometry) from in-situ samples, duration 10-15 days. Read More

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February 2021

Toothpastes and recurrent aphthous stomatitis.

Authors:
Reena Wadia

Br Dent J 2020 12;229(12):786

Specialist Periodontist at RW Perio and Associate Specialist at King's College Dental Hospital, London, UK.

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December 2020

Nanoparticle-Based Devices in the Control of Antibiotic Resistant Bacteria.

Front Microbiol 2020 25;11:563821. Epub 2020 Nov 25.

Laboratory of Biomedicine Santiago Ramón y Cajal, Sociedad Española de Beneficencia, Pachuca, Mexico.

Antimicrobial resistance (AR) is one of the most important public health challenges worldwide as it represents a serious complication that is able to increase the mortality, morbidity, disability, hospital stay and economic burden related to infectious diseases. As such, the spread of AR-pathogens must be considered as an emergency, and interdisciplinary approaches must be undertaken in order to develop not only drugs, but holistic strategies to undermine the epidemic and pathogenic potentials of multi-drug resistant (MDR) pathogens. One of such approaches has focused on the use of antimicrobial nanoparticles (ANPs), as they have demonstrated to possess strong antimicrobial effects on MDR pathogens. Read More

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November 2020

Effect of fluoride, casein phosphopeptide-amorphous calcium phosphate and sodium trimetaphosphate combination treatment on the remineralization of caries lesions: An in vitro study.

Arch Oral Biol 2021 Feb 2;122:105001. Epub 2020 Dec 2.

São Paulo State University (UNESP), School of Dentistry, Araçatuba Department of Preventive and Restorative Dentistry, Rua José Bonifácio 1193 Araçatuba, SP, Cep 16015-050, Brazil; School of Dentistry, University of Ribeirão Preto - UNAERP, Ribeirão Preto, SP, Cep 14096-900, Brazil. Electronic address:

Objective: To evaluate the effects of combination of treatments with fluoridated toothpastes supplemented with sodium trimetaphosphate (TMP) and casein phosphopeptide-amorphous calcium phosphate (MI Paste Plus®), on the remineralization of dental enamel.

Design: Enamel blocks with artificial caries were randomly allocated into six groups (n = 12), according to the toothpastes: 1) without F-TMP-MI Paste Plus® (Placebo); 2) 1100 ppm F (1100 F), 3) MI Paste Plus®, 4) 1100 F + MI Paste Plus® (1100 F-MI Paste Plus®), 5) 1100 F + 3% TMP (1100 F-TMP) and 6) 1100 F-TMP + MI Paste Plus® (1100 F-TMP-MI Paste Plus®). Blocks were treated 2×/day with slurries of toothpastes (1 min). Read More

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February 2021

Activated Charcoal-based Dental Products: Awareness, Knowledge and Opinion of Dental Practitioners in a Tertiary Hospital in Nigeria.

West Afr J Med 2020 Dec;37(7):732-739

Department of Preventive Dentistry, Faculty of Dentistry, University of Port Harcourt, Port Harcourt, Rivers State,Nigeria.

Background: Recently, there is a resurgence in the practice of oral hygiene with charcoal-based oral hygiene products such as charcoal based dentifrices, toothbrushes and mouthwashes. Dental professionals need to be aware of these products to rightly educate patients on acclaimed merits and demerits.

Objective: To elicit the awareness, knowledge and opinion of dental professionals on the use of activated charcoal oral health products. Read More

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December 2020

Demineralization Inhibitory Effects of Highly Concentrated Fluoride Dentifrice and Fluoride Gels/Solutions on Sound Dentin and Artificial Dentin Caries Lesions in vitro.

Caries Res 2021 7;55(1):41-54. Epub 2020 Dec 7.

Department of Restorative, Preventive and Pediatric Dentistry, zmk Bern, University of Bern, Bern, Switzerland.

Objectives: The aim of this in vitro study was to compare the demineralization inhibitory effect of gels/solutions used in combination with either standard or highly fluoridated dentifrices on sound dentin as well as on artificial dentin caries-like lesions.

Methods: Bovine dentin specimens (n = 240) with two different surfaces each (sound [ST] and artificial caries lesion [DT]) were prepared and randomly allocated to twelve groups. Weekly interventions during pH-cycling (28 days, 6 × 120 min demineralization/day) were: the application of gels/solutions containing amine fluoride/sodium fluoride (12,500 ppm F [ppm]; pH = 4. Read More

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December 2020

Bioactive glass versus Arginine dentifrices on the reduction of dentin permeability and acid tolerance.

Clin Exp Dent Res 2020 Dec 6. Epub 2020 Dec 6.

Department of Periodontology, Faculty of Dentistry, Chulalongkorn University, Bangkok, Thailand.

Objectives: To compare the efficacy of calcium sodium phosphosilicate (CSPS) and arginine dentifrices on dentin permeability and acid tolerance.

Material And Methods: Sixty dentin discs were randomly assigned into 3 groups, then brushed for 1 min with CSPS, arginine, or fluoride (control) dentifrices. To test acid tolerance, each disc was soaked in 6% citric acid for 1 min. Read More

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December 2020

Can Desensitizing Toothpastes Also Have an Effect on Gingival Inflammation? A Double-Blind, Three-Treatment Crossover Clinical Trial.

Int J Environ Res Public Health 2020 12 1;17(23). Epub 2020 Dec 1.

Department of Clinical Sciences and Stomatology, Polytechnic University of Marche, Via Tronto 10, 60126 Ancona, Italy.

Background: Many desensitizing toothpastes exist commercially; however, few clinical trials have investigated their anti-inflammatory effects. This study aimed to evaluate the anti-inflammatory effect and patient appreciation of two toothpastes containing desensitizing agents: (1) a zinc-carbonate-hydroxyapatite nanoparticle (CHA) and (2) a calcium sodium phosphosilicate bioactive glass (CSPS).

Methods: CHA and CSPS were compared with an anti-inflammatory and antibacterial herbal based toothpaste (HB). Read More

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December 2020

Inter-method reliability for determining total and soluble fluorides in child low-fluoride formula dentifrices.

Sci Rep 2020 11 30;10(1):20880. Epub 2020 Nov 30.

2/F, Paediatric Dentistry, Prince Philip Dental Hospital, Faculty of Dentistry, The University of Hong Kong, 34 Hospital Road, Hong Kong, Hong Kong SAR.

The study aimed to compare three methods for determining total (TF) and total soluble fluorides (TSF) in 5 child formula dentifrices (CFD) using Inter-method reliability (IMR) statistical approach. The methods were direct acid-hydrolysis (DM), the least-time-consuming method; Modified direct acid-hydrolysis with standard-addition method (MDM), ISO 19448:2018 method; and modified Taves acid-HMDS diffusion analysis (TAD), the claimed gold standard method. A significant difference in the mean difference was observed for all methods at all levels (p < 0. Read More

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November 2020

[What to expect from whitening toothpaste?]

Authors:
A A J Jeurissen

Ned Tijdschr Tandheelkd 2020 Nov;127(11):601-605

To assess the whitening effect of whitening toothpastes, their ingredients were studied. These toothpastes turned out to have an influence articularly on the extrinsic discoloration of teeth caused by staining. To a large extent, the effectiveness of the whitening toothpastes relies on removing these extrinsic stains, preventing new stains from developing and on certain optical effects. Read More

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November 2020

Pyrophosphates in toothpaste: a retrospective and reappraisal.

Authors:
Ronnie S Levine

Br Dent J 2020 11 27;229(10):687-689. Epub 2020 Nov 27.

Department of Oral Surgery, University of Leeds School of Dentistry, Worsley Building, Clarendon Way, Leeds, LS2 9LU, UK.

During the last 50 years, an increasing number of toothpastes have been marketed that include pyrophosphates as anti-tartar (calculus) agents. Pyrophosphates are chelating agents with low toxicity and a broad range of applications, such as food additives and in industrial applications. Like other chelating agents, the prime function is to combine with metal elements and, in toothpastes, to inhibit calcium phosphate deposits in the form of dental calculus. Read More

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November 2020