637,406 results match your criteria dental

Relationship between short lingual frenulum and malocclusion. A multicentre study.

Acta Otorrinolaringol Esp (Engl Ed) 2022 May-Jun;73(3):177-183

Rhinology Study Group of the Young-Otolaryngologists of the International Federations of Oto-rhino-laryngological Societies (YO-IFOS), Paris, France; Service of Otolaryngology, Hospital Complex of Santiago de Compostela, Santiago de Compostela, Spain.

Objective: Ankyloglossia is characterized by an abnormally short lingual frenulum, which impairs tongue movement. Ankyloglossia has been related to craniofacial growth disturbances and dental malocclusion. But even though there is a clear biological plausibility for this hypothesis, available evidence is scarce. Read More

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December 2020


J Stomatol Oral Maxillofac Surg 2022 May 13. Epub 2022 May 13.

Professor. Department of Orthodontics. Faculdade São Leopoldo Mandic. Instituto São Leopoldo Mandic. Campinas. São Paulo (SP) Brazil.

Introduction: The gummy smile is perceived in 10% of the population aged 20 to 30 years old, and it causes an aesthetic imbalance in the smile. This study investigated the existence of differences in the aesthetic perception of the smile after correcting the gummy smile using two different techniques: orthognathic surgery for maxillary impaction and miniplate-aided orthodontic impaction.

Methods: Photographs of 16 Long Face Pattern female patients were evaluated by 56 oral and maxillofacial surgeons, 56 orthodontists, and 56 laypeople before and after the treatment with one of the two techniques. Read More

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In vitro biocompatibility testing of 3D printing and conventional resins for occlusal devices: Biocompatibility of 3D printing and conventional resins.

J Dent 2022 May 13:104163. Epub 2022 May 13.

Hematopoietic Transplant and Cellular Therapy Unit, Instituto Murciano de Investigación Biosanitaria Virgen de la Arrixaca, 30120, Murcia, Spain.

Objective: To assess and compare the in vitro biocompatibility of new resins (Keysplint Soft (Keystone Industries), NextDent Ortho Rigid (3D System), and Freeprint Splint (Detax)) and traditional resins (Orthocryl (Dentaurum)) for dental splint.

Methods: Standardized discs (n=40) and 1:1, 1:2, and 1:4 extracts of the tested materials were prepared. Human gingival fibroblasts (hGFs) were isolated from gingival tissues. Read More

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Dental pulp fibroblast: A star Cell.

J Endod 2022 May 13. Epub 2022 May 13.

Specialty in Endodontics, Faculty of Dentistry, University of Cuenca, Ecuador.

Introduction: Dental pulp fibroblasts (DPF) are the most abundant cell type in the dental pulp. They play pivotal roles; however, they are often mistaken to be involved only in the repair and maintenance of this connective tissue.

Methods: We used the search terms "pulp fibroblast," "complement system proteins," "pulp inflammation," "angiogenesis," and "dentin pulp regeneration" to identify articles from the PubMed and Scopus databases. Read More

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Implementing Augmented Reality to Facilitate the Learning of Oral Histology.

Healthc Inform Res 2022 Apr 30;28(2):170-175. Epub 2022 Apr 30.

Rehabilitation Robotics Lab, Faculty of Rehabilitation Medicine, University of Alberta, Edmonton, Alberta, Canada.

Objectives: The study of biological materials under a microscope is known as histology, which is one of the most challenging subjects for students. Our objective was to develop a learning tool that can reduce the extrinsic load of studying histology and make learning enjoyable and flexible. We used augmented reality (AR) to create a cellphone application called Dental AR. Read More

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VSIG4/CRIg directly regulates early CD8 T cell activation through its counter-receptor in a narrow window.

Biochem Biophys Res Commun 2022 Apr 29;614:100-106. Epub 2022 Apr 29.

Department of Molecular Immunology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan. Electronic address:

T-cell responses are fine-tuned by positive and negative co-signal molecules expressed on immune cells and adjacent tissues. VSIG4 is a newly identified member of the B7 family of ligands, which negatively regulates innate inflammatory and CD4 T cell-mediated responses. However, little is known about the direct effects of VSIG4, which are exerted through an unidentified counter-receptor on CD8 T cells. Read More

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Design, synthesis and structure-activity relationship of 4-(1,1,1,3,3,3-hexafluoro-2-hydroxyisoprop-2-yl)phenylsilane derivatives as liver X receptor agonists.

Bioorg Med Chem 2022 May 4;66:116792. Epub 2022 May 4.

Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University, 2-3-10 Kanda-Surugadai, Chiyoda-ku, Tokyo 101-0062, Japan. Electronic address:

Liver X receptor (LXR) α and LXRβ are nuclear receptors playing key roles in lipid metabolism, and LXR ligands are attractive drug candidates for metabolic disorders. Here we report the structural development of 4-(1,1,1,3,3,3-hexafluoro-2-hydroxyprop-2-yl)phenylsilane derivatives as LXR agonists bearing silyl functionalities as the hydrophobic pharmacophore, based on the structure of the known sulfonamide LXR agonist T0901317. Most of the synthesized compounds exhibit agonistic activity toward LXRs, but the LXR subtype-selectivity differs depending upon the substituents on the silicon atom. Read More

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The risk of COVID-19 death is much greater and age dependent with type I IFN autoantibodies.

Proc Natl Acad Sci U S A 2022 May 16;119(21):e2200413119. Epub 2022 May 16.

Hospices Civils de Lyon, 69002 Lyon, France.

SignificanceThere is growing evidence that preexisting autoantibodies neutralizing type I interferons (IFNs) are strong determinants of life-threatening COVID-19 pneumonia. It is important to estimate their quantitative impact on COVID-19 mortality upon SARS-CoV-2 infection, by age and sex, as both the prevalence of these autoantibodies and the risk of COVID-19 death increase with age and are higher in men. Using an unvaccinated sample of 1,261 deceased patients and 34,159 individuals from the general population, we found that autoantibodies against type I IFNs strongly increased the SARS-CoV-2 infection fatality rate at all ages, in both men and women. Read More

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How To Teach 'Listening For Learning' In A Clinical Context?

J Ayub Med Coll Abbottabad 2022 Apr-Jun;34(2):392-393

Rehman College of Dentistry Peshawar, Pakistan.

Active listening skills are an important factor in communication skill set. And for budding doctors they need to be incorporated in the undergraduate medical programs. Studies have shown that patients, prefer the doctors who can listen to them instead of just looking at their signs and symptoms. Read More

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Prevalence Of Gustatory And Olfactory Impairment In Different Stages Of Sars-Cov-2 Infected Pateints In Isolation Ward.

J Ayub Med Coll Abbottabad 2022 Apr-Jun;34(2):313-316

Bibi Aseefa Dental College SMBBMU Larkana, Pakistan.

Background: To evaluate the prevalence of gustatory and olfactory impairment and its correlation with the severity of SARS-Cov-2 infection as per WHO guidelines.

Methods: A total of 241 patients of both gender having age from 15-80 years were included in the study. It was cross Sectional study conducted at SARS-COV-2 Isolation wards of Pakistan institute of medical science Islamabad from 15thSeptember 2020 to 15th January 2021. Read More

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Impact Of Covid-19: Faculty Suggestions Regarding Online Medical Teaching.

J Ayub Med Coll Abbottabad 2022 Apr-Jun;34(2):304-308

Rashid Latif Medical Complex, Lahore, Pakistan.

Background: As a result of the SARS-CoV-2 related government lockdown, academic institutions in Pakistan, including medical and dental colleges and universities, had to forgo on-site classes and make an emergency shift to online teaching. This study explores the perspective of the faculty, as a key stakeholder, on ways to increase the effectiveness of online teaching and learning at these medical and dental colleges and universities.

Methods: A descriptive cross-sectional qualitative survey was conducted in April-July 2020 in 32 medical and dental colleges of Pakistan. Read More

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Quantification Of Thrombus Burden As An Independent Predictor Of Intra-Procedural No-Reflow In Patients With St-Segment Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Revascularization.

J Ayub Med Coll Abbottabad 2022 Apr-Jun;34(2):288-294

National Institute of Cardiovascular Diseases, Karachi, Pakistan.

Background: Aim of this study was to perform quantitative evaluation of high thrombus burden (Grade ≥4) as an independent predictor of slow/no reflow phenomenon during primary percutaneous coronary interventions (PCI) of patients with ST-segment elevation myocardial infarction (STEMI).

Methods: In this analytical cross-sectional study we included consecutive patients who have undergone primary PCI for STEMI at a tertiary care cardiac center of the Pakistan. High thrombus burden was defined as angiographic thrombus grade ≥4. Read More

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Analytical Study Of Salivary Mmp-12 Expression In Oral Submucous Fibrosis.

J Ayub Med Coll Abbottabad 2022 Apr-Jun;34(2):247-250

Department of Oral and Maxillofacial Surgery, Dow university of Health Sciences, Karachi.

Background: Oral submucous fibrosis (OSF) is majorly a pathology pertaining to Asian population, reported most in Pakistan, India, Nepal, Bangladesh, and Taiwan. Equilibrium existing between Matrix metalloproteinases (MMP) & tissue inhibitors of matrix metalloproteinases is imperative for the normal integrity of connective tissues. However, this mechanism is disturbed in the presence of OSF, resulting in an increase in the extracellular matrix. Read More

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Interleukin-34 Permits Porphyromonas gingivalis Survival and NF-κB p65 Inhibition in Macrophages.

Mol Oral Microbiol 2022 May 16. Epub 2022 May 16.

Department of Oral Biology, School of Dental Medicine, University at Buffalo, 3435 Main Street, Buffalo, NY, 14214, USA.

Interleukin-34 (IL-34) is a cytokine that supports the viability and differentiation of macrophages. An important cytokine for the development of epidermal immunity, IL-34 is present and plays a role in the immunity of the oral environment. IL-34 has been linked to inflammatory periodontal diseases, which involve innate phagocytes, including macrophages. Read More

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Metastases to the Parotid Gland: Study from a Tertiary Care Centre.

Head Neck Pathol 2022 May 16. Epub 2022 May 16.

Department of Radiation Oncology, BRA Institute Rotary Cancer Hospital and National Cancer Institute, All India Institute of Medical Sciences, New Delhi, 110029, India.

Background: Metastases account for 6-25% of parotid tumors, often presenting dilemmas in their diagnosis.

Methods: Parotid metastases diagnosed on histology/cytology were retrieved. MUC2, MUC5AC, androgen receptor immunohistochemistry was performed in select cases. Read More

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Distribution of mature and newly regenerated nerve fibers after tooth extraction and dental implant placement: an immunohistological study.

J Oral Rehabil 2022 May 16. Epub 2022 May 16.

Department of Prosthodontics, Peking University School and Hospital of Stomatology & National Center of Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Research Center of Oral Biomaterials and Digital Medical Devices & Beijing Key Laboratory of Digital Stomatology & Research Center of Engineering and Technology for Computerized Dentistry Ministry of Health & NMPA Key Laboratory for Dental Materials, Beijing, P.R. China.

Background: The time-dependent peri-implant innervation needs to be elucidated in detail.

Objectives: To examine the distribution of mature and newly regenerated nerves around the implant with immunofluorescence during 28-days follow-up after implantation.

Methods: 35 male Sprague-Dawley rats were grouped into non-operated(n=5), extraction(n=5), and implant(n=25) groups. Read More

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The bacteriostatic effect of erythritol on canine periodontal disease-related bacteria.

Pol J Vet Sci 2022 Mar;25(1):75-82

Department of Gastroenterology and Hepatology, Fujita Health University, Toyoake, Aichi 470-1192, Japan.

Erythritol helps both prevent and improve periodontal disease and is therefore widely used for dental care in humans. However, only a few studies have investigated the effects of erythritol on periodontal disease in animals. We hypothesized that erythritol could be used to prevent and improve periodontal disease also in canines and investigated the effects of erythritol on canine periodontal disease-related pathogenic bacteria using both in vitro and in vivo methods. Read More

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Dental Care Utilization Among Adults Aged 18-64: United States, 2019 and 2020.

NCHS Data Brief 2022 Apr(435):1-8

Oral health is an essential component of overall health and well-being (1,2). Along with good oral hygiene, an important factor of oral health is regular dental care (3). However, about 35% of adults aged 18 and over did not have a dental visit in 2019 (4), and predictors such as age, race, sex, and socioeconomic status were associated with delayed dental care among adults in the United States (5). Read More

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Surface Treatments and Adhesives Used to Increase the Bond Strength Between Polyetheretherketone and Resin-based Dental Materials: A Scoping Review.

J Adhes Dent 2022 May;24(1):233-245

Purpose: To identify and discuss the available surface treatments and adhesives for polyetheretherketone (PEEK) to increase its bond strength to resin-based materials used in dentistry.

Materials And Methods: The reporting of this scoping review was based on PRISMA. The study protocol was made available at: https://osf. Read More

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Bat Dentitions: A Model System for Studies at The Interface of Development, Biomechanics, and Evolution.

Integr Comp Biol 2022 May 16. Epub 2022 May 16.

University of California Los Angeles, CA.

The evolution of complex dentitions was a major innovation in mammals that facilitated the expansion into new dietary niches that imposed selection for tight form-function relationships. Teeth allow mammals to ingest and process food items by applying forces produced by a third-class lever system composed by the jaw adductors, the cranium, and the mandible. Physical laws determine changes in jaw adductor (biting) forces at different bite point locations along the mandible (outlever), thus individual teeth are expected to experience different mechanical regimes during feeding. Read More

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Raffinose Inhibits Streptococcus mutans Biofilm Formation by Targeting Glucosyltransferase.

Microbiol Spectr 2022 May 16:e0207621. Epub 2022 May 16.

School of Civil, Environmental, and Architectural Engineering, Korea Universitygrid.222754.4, Seoul, South Korea.

Streptococcus mutans is a representative biofilm-forming bacterium that causes dental caries through glucosyltransferase (GTF) activity. Glucans are synthesized from sucrose by GTFs and provide binding sites for S. mutans to adhere tightly to the tooth enamel. Read More

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LeFort III/I for Beckwith-Wiedemann Syndrome: A Case Report.

Cleft Palate Craniofac J 2022 May 15:10556656221101776. Epub 2022 May 15.

12297NYU Langone Health, New York, NY, USA.

This case presents a facially mature patient with Beckwith-Wiedemann Syndrome (BWS) who presented with severe class III malocclusion. Computed tomography imaging revealed an anterior crossbite of 19 mm and a narrow pharyngeal airway at the level of the tongue base precluding mandibular setback surgery. The patient was indicated for a LeFort III combined with a LeFort I advancement, each of 10 mm, for a 20 mm combined advancement. Read More

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Equine odontoclastic tooth resorption and hypercementosis: investigating individual incisor disease patterns using radiological classification.

Equine Vet J 2022 May 16. Epub 2022 May 16.

Equine Clinic: Surgery and Radiology, Department of Veterinary Medicine, Freie Universität Berlin, Oertzenweg 19b, Berlin, Germany.

Background: Equine odontoclastic tooth resorption and hypercementosis (EOTRH) is a destructive, painful, and underdiagnosed dental disorder. Radiography is necessary to fully assess the disease as early stages occur on clinically normal teeth.

Objectives: To investigate the distribution pattern of appearance of EOTRH within the incisor arcade. Read More

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Development of Social Life Impact for Mother (SLIM) scale at first trimester to identify mothers who need social support during postpartum: a hospital-based prospective study in Japan.

Int J Gynaecol Obstet 2022 May 16. Epub 2022 May 16.

Department of Maternal Fetal Medicine, Osaka Women's and Children's Hospital, 840 Murodo-cho, Izumi, Osaka, Japan.

Objective: Postpartum social problems, such as postpartum depression and bonding disorders, are important risk factors for child maltreatment. Mothers with such problems are known to need social support. The aim of this study was to develop and validate the Social Life Impact for Mother (SLIM) scale to identify mothers in Japan who need social support during postpartum. Read More

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Nitrite Generating and Depleting Capacity of the Oral Microbiome and Cardiometabolic Risk: Results from ORIGINS.

J Am Heart Assoc 2022 May 16:e023038. Epub 2022 May 16.

Division of Epidemiology and Community Health School of Public Health University of Minnesota Minneapolis MN.

Background The enterosalivary nitrate-nitrite-nitric oxide (NO-NO-NO) pathway generates NO following oral microbiota-mediated production of salivary nitrite, potentially linking the oral microbiota to reduced cardiometabolic risk. Nitrite depletion by oral bacteria may also be important for determining the net nitrite available systemically. We examine if higher abundance of oral microbial genes favoring increased oral nitrite generation and decreased nitrite depletion is associated with a better cardiometabolic profile cross-sectionally. Read More

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Rehabilitation Definition for Research Purposes. A Global Stakeholders' Initiative by Cochrane Rehabilitation.

Neurorehabil Neural Repair 2022 May 16:15459683221093587. Epub 2022 May 16.

Members are listed at the end of the paper.

Since its foundation, Cochrane Rehabilitation has faced challenges with rehabilitation definitions because existing definitions did not indicate what rehabilitation includes and what it excludes. We aimed to develop a comprehensive and shared rehabilitation definition for research purposes to: (1) support the conduct of primary studies and systematic reviews, and (2) identify relevant systematic reviews for knowledge translation purposes. We performed a multimodal study including seven preliminary research and discussion papers, four Consensus Meetings, and three Delphi rounds with 80 rehabilitation stakeholders. Read More

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Ultrasound-guided placement of Long Peripheral Cannula in children with Cystic Fibrosis.

Pediatr Pulmonol 2022 May 16. Epub 2022 May 16.

Division of Anesthesia and Critical Care - Department of Human Pathology of the adult and evolutive age "Gaetano Barresi", University of Messina.

Background: The natural history of cystic fibrosis (CF) lung disease is a chronic deterioration of lung function with intermittent episodes of pulmonary infectious exacerbations (PExs). Reliable venous access is a milestone of effective management of such exacerbations, managed both in hospital and outpatient chronic therapy. The aim of our study was to analyse the feasibility of ultrasound-guided positioning of Long Peripheral Catheters (LPC) as reliable mid-term venous access in children affected by CF. Read More

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Dentists, are you ready to deal with the "smokers of the future "?

Hum Exp Toxicol 2022 Jan-Dec;41:9603271221101052

Department of Biosciences and Oral Diagnosis, Institute of Science and Technology, São Paulo State University (UNESP), São José dos Campos, São Paulo, Brazil.

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Complex cross-talk between EZH2 and miRNAs confers hallmark characteristics and shapes the tumor microenvironment.

Epigenomics 2022 May 16. Epub 2022 May 16.

Division of Surgery & Interventional Science, Royal Free London NHS Foundation Trust, University College London, London, NW3 2QG, UK.

Cancer epigenetic mechanisms support the acquisition of hallmark characteristics during oncogenesis. EZH2 - an important histone methyltransferase that writes histone H3 lysine 27 trimethylation marks - is known to be dysregulated in cancer cells. However, the interactions between EZH2 and miRNAs that form a complex network of cross-talk and reciprocal regulation that enable cancer cells to acquire hallmark characteristics have been relatively poorly appreciated. Read More

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Molecular docking analysis of penta galloyl glucose with the bcl-2 family of anti-apoptotic targets.

Bioinformation 2021 31;17(10):861-865. Epub 2021 Oct 31.

Department of Biochemistry, All India Institute of Medical Sciences, Jodhpur, Rajasthan- 342005, India.

Apoptosis requires cellular proteins from the B-cell lymphoma 2 (BCL-2) family linked to breast cancer. Therefore, it is of interest to document the Molecular docking analysis data of penta galloyl glucose with the bcl-2 family of anti-apoptotic targets (Bcl-2, BCL-XL, Caspase 3, and Caspase 9). Data shows that Pentagalloyl glucose have optimal binding features with Bcl-2, BCL-XL, Caspase 3, and Caspase 9 proteins with binding energy of -8. Read More

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October 2021