4 results match your criteria density ev-induced

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Cyclophilin A regulates secretion of tumour-derived extracellular vesicles.

Transl Oncol 2021 Aug 10;14(8):101112. Epub 2021 May 10.

UCD School of Biomolecular & Biomedical Science, Conway Institute, University College Dublin (UCD), Belfield, Dublin 4, Ireland. Electronic address:

Extracellular Vesicles (EVs) are a heterogenous population of particles that play an important role in cell-cell communication in physiological and pathophysiological situations. In this study we reveal that the peptidyl prolyl isomerase Cyclophilin A (CypA) is enriched in cancer-derived EVs from a range of haematopoietic malignancies. CypA-enriched blood cancer EVs were taken up by normal monocytes independent of EV surface trypsin-sensitive proteins and potently stimulated pro-inflammatory MMP9 and IL-6 secretion. Read More

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Molecular and Epigenetic Basis of Extracellular Vesicles Cell Repair Phenotypes in Targeted Organ-specific Regeneration.

Curr Mol Med 2021 Feb 10. Epub 2021 Feb 10.

Faculty of Applied Science, Universiti Teknologi MARA (UiTM), Sarawak Branch, Mukah Campus, KM 7.5, Jalan Mukah-Oya, 96400, Mukah, Sarawak. Malaysia.

Extracellular vesicles (EVs), which released by most of the cells, constitute a new system of cell-cell communication by transporting DNA, RNA and proteins, in various vesiclesnamely exosomes, apoptotic bodies, protein complexes, high-density lipid (HDL) microvesicles, among others.To ensure accurate regulation of somatic stem cell activity, EVs function as an independent metabolic unit mediating the metabolic homeostasis and pathophysiological of several diseases such as cardiovascular diseases, metabolic diseases, neurodegenerative diseases,immune diseases andcancer. Whist examining the EV biomolecules cargos and its microenvironments that lead to epigenetic alteration of the cell in tissue regeneration, studies have gainedfurther insights into the biogenesis of EVs and their potential roles in cell biology and pathogenicity. Read More

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February 2021

Mechanisms underlying the protective effect of montelukast in prevention of endometrial hyperplasia in female rats.

Int Immunopharmacol 2018 Sep 26;62:326-333. Epub 2018 Jul 26.

Department of Obstetrics and Gynecology, Faculty of Medicine, Minia University, Egypt.

Objective: To study the possible protective role of montelukast in endometrial hyperplesia (EH) rat model, induced by estradiol valerate (EV).

Methods/materials: Thirty six female albino Wistar rats were classified into 7 groups: normal control, EV (2 mg/kg/day, p.o. Read More

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September 2018

Hydrogen-induced blistering mechanisms in thin film coatings.

J Phys Condens Matter 2012 Feb 23;24(5):052203. Epub 2011 Dec 23.

FOM Institute for Plasma Physics Rijnhuizen, Postbus 1207, 3430 BE Nieuwegein, The Netherlands3.

We report on the mechanisms of hydrogen-induced blistering of multilayer coatings. Blister formation is a result of highly localized delamination occurring at the two outermost metal-on-silicon interfaces. The number, size, and type of blisters formed varied depending on the composition and ion energy of the incident flux. Read More

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February 2012
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