121,946 results match your criteria demonstrated differences

Evaluation of the sequential coupling of a bacterial treatment with a physicochemical process for the remediation of wastewater containing Cr and organic pollutants.

J Hazard Mater 2021 Jun 6;418:126307. Epub 2021 Jun 6.

Planta Piloto de Procesos Industriales Microbiológicos (PROIMI), CONICET, Av. Belgrano y Pasaje Caseros, 4000 Tucumán, Argentina; Facultad de Ciencias Naturales e Instituto Miguel Lillo, Universidad Nacional de Tucumán, Miguel Lillo 205, 4000 Tucumán, Argentina. Electronic address:

A restoration strategy was developed for the treatment of two artificial liquid systems (Minimal Medium, MM, and Water Carbon Nitrogen, WCN) contaminated with Cr(VI), lindane (γ-HCH), phenanthrene (Phe), and reactive black 5 (RB5), through the use of an actinobacteria consortium, coupled with a physicochemical treatment using a column filled with nano-scale zero valent iron particles immobilized on dried Macrocystis pyrifera algae biomass. The Sequential Treatment A (ST: physicochemical followed by biological method) removed the three organic compounds with different effectiveness; however, it was very ineffective for Cr(VI) removal. The Sequential Treatment B (ST: biological followed by the physicochemical method) removed the four compounds with variable efficiencies. Read More

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Promoting cross-regional collaboration in antimicrobial stewardship: Findings of an infectious diseases working group survey in Arab countries of the Middle East.

J Infect Public Health 2021 Apr 24;14(7):978-984. Epub 2021 Apr 24.

American University of Beirut Medical Center, Beirut, Lebanon. Electronic address:

Background: Antimicrobial resistance is a significant global issue that presents an increasing threat to patients' wellbeing. Although a global concern, the emergence of multi-drug resistant organisms is of particular significance in the Middle East. In recent years, this region has seen an alarming increase in antimicrobial resistance presenting a major challenge to physicians managing various infectious diseases. Read More

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The association between bladder dysfunction, balance and falls in women with multiple sclerosis: The specific contribution of fear of falling.

Gait Posture 2021 Jun 10;88:252-257. Epub 2021 Jun 10.

Department of Physical Therapy, School of Health Professions, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel; Multiple Sclerosis Center, Sheba Medical Center, Tel Hashomer, Israel; Sagol School of Neuroscience, Tel-Aviv University, Tel Aviv, Israel. Electronic address:

Background: Bladder dysfunction is the most common autonomic disturbance in people with MS (PwMS). Only a few studies have examined the relationship between bladder dysfunction and falls in PwMS. Bladder dysfunction has been deemed only a secondary outcome measure, and classified by a gross measure providing a limited perspective of this disturbing symptom. Read More

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Method for characterization of dynamic ankle stiffness in patients with spasticity.

Gait Posture 2021 Jun 8;88:247-251. Epub 2021 Jun 8.

Motion Analysis Laboratory, Department of Orthopedic Surgery, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA. Electronic address:

Background: Dynamic ankle stiffness has been quantified as the slope of the ankle joint moment-angle curve over the gait interval of the second rocker, defined explicitly as the period of the gait cycle from the first relative maximum plantar flexion in early stance to maximum dorsiflexion in midstance. However, gastrocnemius spasticity may interfere with the second ankle rocker in patients with spasticity. This gait disruption results in stiffness calculations which are misleading. Read More

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Everyday interactions support toddlers' learning of conventional actions on artifacts.

J Exp Child Psychol 2021 Jun 12;210:105201. Epub 2021 Jun 12.

Department of Psychology, University of Chicago, Chicago, IL 60637, USA.

Children learn to perform actions on artifacts in their environments from infancy, but the ways caregivers support this learning during everyday interactions are relatively unexplored. This study investigated how naturalistic caregiver-child teaching interactions promoted conventional action learning in toddlers. Caregivers of 32 24- to 26-month-old children taught their children to perform novel target actions on toys. Read More

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In vivo evaluation of deer antler trabecular bone as a reconstruction material for bone defects.

Res Vet Sci 2021 Jun 11;138:116-124. Epub 2021 Jun 11.

Department of Clinical Sciences, FARAH, Faculty of Veterinary Medicine, University of Liège, Quartier Vallée 2, Avenue de Cureghem 1 - B67, Liège, Belgium.

Availability of graft materials to fill up osseous defects has always been a concern in orthopaedic surgeries. Deer antler material is a primary bone structure that is easy to collect and could serve as a xenograft. This study examines the behaviour of red deer antler trabecular cylinders in critical size distal femoral epiphyseal defects in 11 rabbits, and evaluates the effect of the decellularization protocols. Read More

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Effects of Nanocrystalline Hydroxyapatite Concentration and Skeletal Site on Bone and Cartilage Formation in Rats.

Acta Biomater 2021 Jun 12. Epub 2021 Jun 12.

Department of Biomedical Engineering, Vanderbilt University, 2201 West End Ave, Nashville TN 37235; Department of Chemical and Biomolecular Engineering, Vanderbilt University, 2201 West End Ave, Nashville TN 37235; Vanderbilt Center for Bone Biology, Vanderbilt University Medical Center, 1211 Medical Center Dr., Nashville, TN 37212; Division of Clinical Pharmacology, Department of Medicine, Vanderbilt University Medical Center, 1211 Medical Center Dr., Nashville, TN 37217. Electronic address:

Most fractures heal by a combination of endochondral and intramembranous ossification dependent upon strain and vascularity at the fracture site. Many biomaterials-based bone regeneration strategies rely on the use of calcium phosphates such as nano-crystalline hydroxyapatite (nHA) to create bone-like scaffolds. In this study, nHA was dispersed in reactive polymers to form composite scaffolds that were evaluated both in vitro and in vivo. Read More

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The role of sexual dimorphism in susceptibility to SARS-CoV-2 infection, disease severity, and mortality: facts, controversies and future perspectives.

Microbes Infect 2021 Jun 12:104850. Epub 2021 Jun 12.

Division of Endocrinology and Metabolism and Diabetes Center, First Department of Internal Medicine, Medical School, Aristotle University of Thessaloniki, AHEPA University Hospital, Thessaloniki, Greece. Electronic address:

Former studies have revealed intersex variability in immune response to infectious diseases, including Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Epidemiological surveillance of the ongoing pandemic has demonstrated a male vulnerability to morbidity and mortality, despite similar infection rates between the two sexes. Divergence in the frequency of comorbidities between males and females, differences in hormonal profile, chromosomal composition and gender behavior have all been proposed as potential causative factors. Read More

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Transcriptional profiling of primary prostate tumor in metastatic hormone-sensitive prostate cancer and association with clinical outcomes: correlative analysis of the E3805 CHAARTED study.

Ann Oncol 2021 Jun 12. Epub 2021 Jun 12.

Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA. Electronic address:

Background: The phase III CHAARTED trial established upfront androgen deprivation therapy (ADT) plus docetaxel (D) as a standard for metastatic hormone-sensitive prostate cancer (mHSPC) based on meaningful improvement in overall survival (OS). Biological prognostic markers of outcomes and predictors of chemotherapy benefit are undefined.

Patients And Methods: Whole transcriptomic profiling was performed on primary prostate cancer (PC) tissue obtained from patients enrolled in CHAARTED prior to systemic therapy. Read More

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Starting pitchers demonstrate a greater hazard of arm injury compared to relief pitchers.

J Athl Train 2021 Jun 15. Epub 2021 Jun 15.

University of South Carolina Center for Rehabilitation and Reconstruction Sciences, Greenville, South Carolina, USA.

Context: It is currently unclear how different pitching roles affect arm injury risk in professional pitchers.

Objective: 1) Investigate the differences in arm injury hazard between professional baseball starting and relief pitchers; 2) Separately investigate elbow and shoulder injury hazard between professional baseball starting and relief pitchers.

Study Design: Prospective cohort Setting: Minor League Baseball (MiLB) from 2013-2019 Patients or Other Participants: Pitchers Main Outcome Measures: Pitchers were followed for the entire MiLB season and athletic exposures (AE's) and injuries were recorded. Read More

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Attitudes, beliefs and behaviors of religiosity, spirituality, and cultural competence in the medical profession: A cross-sectional survey study.

PLoS One 2021 15;16(6):e0252750. Epub 2021 Jun 15.

University of South Carolina School of Medicine Greenville, Greenville, South Carolina, United States of America.

Introduction: Religion and spirituality play important roles in the lives of many, including healthcare providers and their patients. The purpose of this study was to examine the relationships between religion, spirituality, and cultural competence of healthcare providers.

Methods: Physicians, residents, and medical students were recruited through social platforms to complete an electronically delivered survey, gathering data regarding demographics, cultural competency, religiosity, and spirituality. Read More

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Comparative Analysis of Pediatric COVID-19 Infection in Southeast Asia, South Asia, Japan, and China.

Am J Trop Med Hyg 2021 Jun 15. Epub 2021 Jun 15.

Duke-NUS Medical School, Singapore.

There is a scarcity of data regarding coronavirus disease 2019 (COVID-19) infection in children from southeast and south Asia. This study aims to identify risk factors for severe COVID-19 disease among children in the region. This is an observational study of children with COVID-19 infection in hospitals contributing data to the Pediatric Acute and Critical Care COVID-19 Registry of Asia. Read More

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Event-related Beta EEG changes Induced by Various Neuromuscular Electrical Stimulation: A Pilot Study.

IEEE Trans Neural Syst Rehabil Eng 2021 Jun 15;PP. Epub 2021 Jun 15.

Previous results demonstrated that neuromuscular electrical stimulation (NMES) with various configurations could induce different activity at both the central and peripheral levels. Although NMES generating different peripheral movements have been studied, it is still unclear whether the difference in NMES-induced cortical activity is due to movement-or stimulation-related differences. Because NMES-induced cortical activity impacts motor function recovery, it is essential to know when NMES with various configurations evoke the same movement, whether the induced cortical activity is still different. Read More

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Elevated Anti-Müllerian Hormone Levels in Newborns of Women with Polycystic Ovary Syndrome: a Systematic Review and Meta-analysis Based on Observational Studies.

Reprod Sci 2021 Jun 15. Epub 2021 Jun 15.

Department of Obstetrics and Gynaecology, West China Second University Hospital, Sichuan University, Chengdu, China.

We performed this updated systematic review and meta-analysis to evaluate anti-Müllerian hormone levels (AMH) in newborns of mothers with polycystic ovary syndrome (PCOS) compared with healthy controls. A search of the literature was conducted in the PubMed, MEDLINE, EMBASE, Cochrane Library, CBM, CNKI, WANFANG, and VIP for articles to assess AMH levels in offspring of PCOS and non-PCOS mothers irrespective of language. These databases were searched from their inception to December 7, 2020. Read More

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Flow-diverting device versus coil embolization for unruptured intracranial aneurysm: A meta-analysis.

Medicine (Baltimore) 2021 Jun;100(24):e26351

Department of Interventional Treatment, Binzhou People's Hospital, Binzhou, China.

Background: Both coil embolization (CE) and flow-diverting device (FDD) placement are widely used for treatment of intracranial aneurysms (IAs). The aim of this meta-analysis is to compare the relative clinical safety and efficacy of FDD and CE for the treatment of unruptured IAs.

Methods: The PubMed, Embase, and Cochrane Library databases were searched for relevant studies from the date of inception through April 2020. Read More

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Normal fetal development of the cervical, thoracic and lumbar spine: a post-mortem study based on magnetic resonance imaging.

Prenat Diagn 2021 Jun 15. Epub 2021 Jun 15.

Shandong Provincial Hospital Affliated to Shandong First Medical University, Jinan, Shandong, 250021, China.

Objective: Before evaluating spinal pathology, it is essential to have knowledge of the normal spinal development at different gestational ages. This study aims to characterize normal spinal growth in human fetuses during the second and third trimester.

Methods: Postmortem 3. Read More

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Brain networks in patients with isolated or recurrent transient global amnesia.

Acta Neurol Scand 2021 Jun 15. Epub 2021 Jun 15.

Department of Neurology, Haeundae Paik Hospital, Inje University College of Medicine, Busan, Korea.

Objectives: The aim of this study was to investigate differences in cerebral blood flow (CBF) and functional networks between transient global amnesia (TGA) patients with a single event and those with recurrent events using arterial spin labeling (ASL) MRI.

Methods: We enrolled patients with TGA and classified them into two groups according to the number of TGA events: TGA patients with a single event and those with recurrent events. MRI scans were performed within 24 h after TGA ictal onset in all patients. Read More

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Analgesic efficacy of ultrasound-guided transversus abdominis plane block after cesarean delivery: A systematic review and meta-analysis.

J Obstet Gynaecol Res 2021 Jun 15. Epub 2021 Jun 15.

Obstetrics Department, Tianjin Central Hospital of Obstetrics and Gynecology, Tianjin, China.

Purpose: The meta-analysis is aimed to further access the analgesic efficacy of ultrasound-guided transversus abdominis plane (USG-TAP) block after cesarean section (CS).

Methods: Electronic databases were searched for eligible studies. Primary objectives were pain-related outcomes. Read More

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Sleep timing and consistency are associated with the standardised test performance of Icelandic adolescents.

J Sleep Res 2021 Jun 14:e13422. Epub 2021 Jun 14.

Diabetes, Endocrinology, and Obesity Branch, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, MD, USA.

Sleep has been shown to affect cognitive function in laboratory studies; however, its association to the academic performance of adolescents has largely been demonstrated using self-reported measures. Studies with objective measures of both sleep and academic performance are limited. The aim of the present study was to determine whether the free-living sleep quantity, quality, and timing of 15-year-old adolescents measured with wrist actiography are associated with their scores on national standardised examinations as an objective measure of academic achievement. Read More

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Evaluation of cadmium and arsenic effects on wild and cultivated cardoon genotypes selected for metal phytoremediation and bioenergy purposes.

Environ Sci Pollut Res Int 2021 Jun 15. Epub 2021 Jun 15.

National Research Council, Institute for Agricultural and Forest Systems in the Mediterranean, Via Empedocle, 58, 95128, Catania, Italy.

Cynara cardunculus L. is a multipurpose crop, characterized by high production of biomass suitable for energy purposes and green chemistry. Taking advantage of its already demonstrated ability to grow in polluted environments that characterize many world marginal lands, the aim of this work was to investigate the response of different cardoon genotypes to exposure to cadmium (Cd) and arsenic (As) pollution, in order to use this crop for rehabilitation of contaminated sites and its biomass for energy production. Read More

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Preferential Oxycodone Loss of Physically Manipulated Abuse Deterrent Oxycodone HCl Extended Release Tablets Prepared for Nasal Insufflation Studies.

Pharm Res 2021 Jun 14. Epub 2021 Jun 14.

Department of Industrial and Physical Pharmacy, Purdue University, RHPH Building, RM 124, 575 Stadium Mall Dr, West Lafayette, Indiana, 47907, USA.

A method to reproducibly mill abuse deterrent oxycodone hydrochloride (HCl) extended release (ER) tablets was developed for a nasal insufflation pharmacokinetic (PK) study. Several comminution methods were explored before determining that a conical mill resulted in controlled milling of tablets to a size range equal to or below 1000 μm. However, milling resulted in significant loss of oxycodone from abuse deterrent oxycodone HCl ER tablets compared to minimal oxycodone loss from oxycodone HCl immediate release (IR) tablets. Read More

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Artificial neural network and logistic regression modelling to characterize COVID-19 infected patients in local areas of Iran.

Biomed J 2021 Feb 25. Epub 2021 Feb 25.

Graduate Student, Dept. of Civil Engineering, Lakehead University, Thunder Bay, ON, Canada.

Background: COVID-19 is an infectious disease that started spreading globally at the end of 2019. Due to differences in patient characteristics and symptoms in different regions, in this research, a comparative study was performed on COVID-19 patients in 6 provinces of Iran. Also, multilayer perceptron (MLP) neural network and Logistic Regression (LR) models were applied for the diagnosis of COVID-19. Read More

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February 2021

[Decrease in the use of bronchodilators in the management of bronchiolitis after applying improvement initiatives].

An Pediatr (Barc) 2021 Jun 11. Epub 2021 Jun 11.

Servicio de Pediatría, Hospital Infantil Universitario Niño Jesús, Madrid, España.

Introduction: In the treatment of patients with acute bronchiolitis there is great variability in clinical practice. Treatments whose efficacy has not been demonstrated are frequently used despite the recommendations contained in the Clinical Practice Guidelines.

Material And Methods: A quality improvement strategy is implemented in the care of patients with acute bronchiolitis in the Emergency Department, which is maintained for five years and is periodically updated to be increasingly restrictive regarding the use of bronchodilators. Read More

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The effects of syringic acid on the properties of MCPA-contaminated soil and the growth of two cucurbit species.

Int J Phytoremediation 2021 Jun 14:1-10. Epub 2021 Jun 14.

UNESCO Chair on Ecohydrology and Applied Ecology, Faculty of Biology and Environmental Protection, University of Lodz, Lodz, Poland.

The aim of this study was to determine the influence of syringic acid (SA), a plant secondary metabolite (PSM), on the properties of soil contaminated with 2-methyl-4-chlorophenoxyacetic acid (MCPA) and the condition of two cucurbit species zucchini ( L. 'Atena Polka') and cucumber ( 'Cezar') grown on that soil. It was found that amendment with MCPA and MCPA + SA modified the soil physico-chemical properties. Read More

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One stone, three birds: one AIEgen with three colors for fast differentiation of three pathogens.

Chem Sci 2020 Apr 14;11(18):4730-4740. Epub 2020 Apr 14.

Department of Chemistry, Hong Kong Branch of Chinese National Engineering Research Center for Tissue Restoration and Reconstruction, Department of Chemical and Biological Engineering, The Hong Kong University of Science and Technology Clear Water Bay Kowloon Hong Kong China

Visually identifying pathogens favors rapid diagnosis at the point-of-care testing level. Here, we developed a microenvironment-sensitive aggregation-induced emission luminogen (AIEgen), namely IQ-Cm, for achieving fast discrimination of Gram-negative bacteria, Gram-positive bacteria and fungi by the naked-eye. With a twisted donor-acceptor and multi-rotor structure, IQ-Cm shows twisted intramolecular charge transfer (TICT) and AIE properties with sensitive fluorescence color response to the microenvironment of pathogens. Read More

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Designing naphthopyran mechanophores with tunable mechanochromic behavior.

Chem Sci 2020 Apr 17;11(17):4525-4530. Epub 2020 Apr 17.

Division of Chemistry and Chemical Engineering, California Institute of Technology Pasadena California 91125 USA

Mechanochromic molecular force probes conveniently report on stress and strain in polymeric materials through straightforward visual cues. We capitalize on the versatility of the naphthopyran framework to design a series of mechanochromic mechanophores that exhibit highly tunable color and fading kinetics after mechanochemical activation. Structurally diverse naphthopyran crosslinkers are synthesized and covalently incorporated into silicone elastomers, where the mechanochemical ring-opening reactions are achieved under tension to generate the merocyanine dyes. Read More

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Distinct Behavior of Traumatic versus Nontraumatic Intracerebral Hematomas: Different Biology or Impact of Age?

J Neurol Surg A Cent Eur Neurosurg 2021 Jun 14. Epub 2021 Jun 14.

Department of General and Trauma Surgery, BG Bergmannsheil University Hospital Bochum, Bochum, Germany.

Background And Study Aims:  Patients with large intracerebral hematomas (ICH) may demonstrate different demographics and underlying brain and systemic diseases, as well as different radiologic courses and distinct outcomes. It remains unclear whether their different behavior attributes to a different biology of the ICH or to the asymmetric characteristics of the two populations. To analyze and adjust for potential sources of selection and treatment bias, our study compared age-matched patients with traumatic and nontraumatic ICH in a single cohort diagnosed and treated in the same surgical department. Read More

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Exploring the ecological and evolutionary relationships between Rickettsia and hard ticks in the Neotropical region.

Ticks Tick Borne Dis 2021 Jun 4;12(5):101754. Epub 2021 Jun 4.

Departamento de Medicina Veterinária Preventiva e Saúde Animal, Faculdade de Medicina Veterinária e Zootecnia, Universidade de São Paulo, Av. Prof. Orlando Marques de Paiva, 87, Cidade Universitária. São Paulo, SP, 05508-270, Brazil.

This study addresses a meta-analysis of the distribution of Rickettsia spp. in the Neotropical region, as well as their associations with ticks and vertebrates. A total of 219 published reports on Rickettsia in ticks in the target region were compiled, providing 599 records of 31 species of Rickettsia recorded in 50 species of Ixodidae. Read More

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Dynamic Assessment of Femoroacetabular Impingement Syndrome Hips.

Arthroscopy 2021 Jun 11. Epub 2021 Jun 11.

Department of Orthopedic Surgery, Hospital for Special Surgery, New York, NY, USA.

Purpose: The purpose of our study was to compare lower extremity rotational kinematics and kinetics (angles, torques, and powers) and hip muscle EMG activity between cam-type FAIS and age-sex matched controls during walking, fast walking, stair ascent, stair descent, and sit-to-stand.

Methods: This study included ten males with unilateral FAIS and ten control males with no FAIS. We measured kinematics, kinetics and electromyographic signals during stair ascent/descent, sit-to-stand, self-selected and fast walk. Read More

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Decline in COPD Admissions During the COVID-19 Pandemic Associated with Lower Burden of Community Respiratory Viral Infections.

Am J Med 2021 Jun 11. Epub 2021 Jun 11.

Division of Pulmonary and Critical Care, University of Maryland School of Medicine. Electronic address:

Background: The COVID-19 pandemic has led to widespread implementation of public health measures, such as stay-at-home orders, social distancing, and masking mandates. In addition to decreasing spread of SARS-CoV2, these measures also impact the transmission of seasonal viral pathogens, which are common triggers of COPD exacerbations. Whether reduced viral prevalence mediates reduction in COPD exacerbation rates is unknown. Read More

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