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Cumulative experience and long term follow-up of pentostatin-based chemoimmunotherapy trials for patients with chronic lymphocytic leukemia.

Expert Rev Hematol 2018 04 26;11(4):337-349. Epub 2018 Feb 26.

d Division of Hematology , Stanford University School of Medicine , Stanford , CA , USA.

Background: 7 regimens of pentostatin based chemoimmunotherapy (CIT) for progressive previously untreated CLL primarily with long term follow-up to update both efficacy and toxicity.

Research Design And Methods: Prognostic markers including assessment of IGVH and FISH status were done on all. Response rates and 95% binomial confidence intervals were calculated for each regimen and in the combined cohort. Read More

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