34,715 results match your criteria december 2019


COULD GENDER IMPACT ON IMMEDIATE AND LONG-TERM CAROTID ARTERY STENTING OUTCOME? INSIGHT FROM AN ITALIAN SINGLE CENTER EXPERIENCE.

Ann Vasc Surg 2021 May 2. Epub 2021 May 2.

Vascular and Endovascular Surgery Unit, Department of Surgery, "Sapienza" University of Rome, Rome, Italy.

Introduction: Carotid artery stenting (CAS) has become a valid alternative to carotid endarterectomy in stroke prevention. However, female gender is still considered as an independent risk factor for CAS procedures, potentially limiting immediate and long-term benefits. Aim of present study was to evaluate gender differences in CAS submitted patients from an Italian high-volume center. Read More

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Diagnostic accuracy of the 4AT for delirium detection in older adults: systematic review and meta-analysis.

Age Ageing 2021 May;50(3):733-743

School of Allied Health, Faculty of Education and Health Sciences, Ageing Research Centre, Health Research Institute, University of Limerick, Limerick, Ireland.

Objective: Detection of delirium in hospitalised older adults is recommended in national and international guidelines. The 4 'A's Test (4AT) is a short (<2 minutes) instrument for delirium detection that is used internationally as a standard tool in clinical practice. We performed a systematic review and meta-analysis of diagnostic test accuracy of the 4AT for delirium detection. Read More

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Do women prefer caesarean sections? A qualitative evidence synthesis of their views and experiences.

PLoS One 2021 5;16(5):e0251072. Epub 2021 May 5.

UNDP/UNFPA/UNICEF/WHO/World Bank Special Programme of Research, Development and Research Training in Human Reproduction (HRP), Department of Sexual and Reproductive Health and Research, World Health Organization, Geneva, Switzerland.

Background: Caesarean sections (CS) continue to increase worldwide. Multiple and complex factors are contributing to the increase, including non-clinical factors related to individual women, families and their interactions with health providers. This global qualitative evidence synthesis explores women's preferences for mode of birth and factors underlying preferences for CS. Read More

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Quality of end-of-life care of home-based care with or without palliative services for patients with advanced illnesses.

Medicine (Baltimore) 2021 May;100(18):e25841

Department of Family Medicine, Tainan Municipal Hospital (Managed by Show Chwan Medical Care Corporation), Tainan, Taiwan.

Abstract: Palliative care has improved quality of end-of-life (EOL) care for patients with cancer, and these benefits may be extended to patients with other serious illnesses. EOL care quality for patients with home-based care is a critical problem for health care providers. We compare EOL quality care between patients with advanced illnesses receiving home-based care with and without palliative services. Read More

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Frequency of Extracorporeal Membrane Oxygenation Support and Outcomes After Implementation of a Structured PICU Network in Neonates and Children: A Prospective Population-Based Study in the West of France.

Pediatr Crit Care Med 2021 May 4. Epub 2021 May 4.

Department of Pediatric Cardiology and Congenital Cardiac Surgery, University Hospital, Nantes, France. Department of Anesthesiology, University Hospital, Nantes, France. Department of Pediatrics, University Hospital, Rennes, France. Department of Pediatrics, Pediatric Intensive Care Unit, University Hospital, Nantes, France. Department of Pediatrics, University Hospital, Nantes, France. Inserm UMR 1153, Obstetrical, Perinatal and Pediatric Epidemiology Research Team (Epopé), Centre of Research in Epidemiology and StatisticS (CRESS), University of Paris, Paris, France. Department of Pediatrics, Neonatal Intensive Care Unit, University Hospital, Rennes, France. Neonatal and Pediatric Intensive Care Unit, University Hospital, Brest, France. Department of Pediatrics, Neonatal Intensive Care Unit, University Hospital, Nantes, France. Department of Pediatrics, Pediatric Intensive Care Unit, University Hospital, Rennes, France.

Objectives: To describe the frequency and outcomes on the use of extracorporeal membrane oxygenation among critically ill neonates and children within a structured pediatric critical care network in the West of France. To assess the optimality of decision-making process for patients primarily admitted in nonextracorporeal membrane oxygenation centers.

Design: Observational prospective population-based study from January 2015 to December 2019. Read More

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The Management of Axillary Lymph Nodes in Breast Cancer - A Retrospective Single-Centre Study.

Chirurgia (Bucur) 2021 Mar-Apr;116(2):186-192

We are presenting the experience of our centre with the surgical treatment of breast cancer, by comparing the use of axillary node dissection with sentinel lymph node biopsy (SNLB). We have made a retrospective analysis of breast cancer cases in the Surgical Oncology Clinic no. 1, "Alexandru Trestioreanu" Oncology Institute, Bucharest, in the period between December 2019 and December 2020. Read More

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Prevalence of Mycobacterium tuberculosis (Rifampicin-Resistant MTB) and Associated Risk Actors Among Pulmonary Presumptive TB Patients in Eastern Amhara, Ethiopia: 2015-2019.

Infect Dis Ther 2021 May 5. Epub 2021 May 5.

Department of Medical Microbiology and Immunology, School of Medicine, Mekelle University, Mekelle, Ethiopia.

Introduction: Tuberculosis (TB) is a major health problem, mainly in resource-limited settings. The aim of this study was to determine the prevalence of TB and rifampicin-resistant Mycobacterium tuberculosis (RR-MTB) among presumptive tuberculosis patients using Xpert MTB/RIF assay in Eastern Amhara, Ethiopia.

Methods: A retrospective cross-sectional study was conducted among presumptive TB patients from three governmental hospitals in Amhara Regional State. Read More

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Internal medicine inpatients' prevalence of misdiagnosed severe osteoporosis.

Osteoporos Int 2021 May 5. Epub 2021 May 5.

Department of Medicine, Internal Medicine and Rheumatology Unit, Azienda Ospedaliero Universitaria di Parma, Via Gramsci 14, 43100, Parma, Italy.

Vertebral fractures (VF) related to osteoporosis (i.e., severe OP) increase the risk of disability and mortality, but they are often neglected. Read More

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Diversification of Academic Surgery, Its Leadership, and the Importance of Intersectionality.

JAMA Surg 2021 May 5. Epub 2021 May 5.

Division of Surgical Oncology, Department of Surgery, Virginia Commonwealth University, Richmond.

Importance: Diversity in academic surgery is lacking, particularly among positions of leadership.

Objective: To evaluate trends among racial/ethnical minority groups stratified by gender along the surgical pipeline, as well as in surgical leadership.

Design, Setting, And Participants: This cross-sectional and longitudinal analysis assessed US surgical faculty census data obtained from the Association of American Medical Colleges faculty roster in the Faculty Administrative Management Online User System database. Read More

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Dynamic α-Fetoprotein Response and Outcomes After Liver Transplant for Hepatocellular Carcinoma.

JAMA Surg 2021 May 5. Epub 2021 May 5.

Multi-Organ Transplant and HPB Surgical Oncology, Division of General Surgery, Toronto General Hospital, University of Toronto, Toronto, Ontario, Canada.

Importance: Accurate preoperative prediction of hepatocellular carcinoma (HCC) recurrence after liver transplant is the mainstay of selection tools used by transplant-governing bodies to discern candidacy for patients with HCC. Although progress has been made, few tools incorporate objective measures of tumor biological characteristics, resulting in inclusion of patients with high recurrence rates and exclusion of others who could otherwise be cured.

Objective: To externally validate the New York/California (NYCA) score, a recently published multi-institutional US HCC selection tool that was the first model incorporating a dynamic α-fetoprotein response (AFP-R) and compare the validated score with currently accepted HCC selection tools, namely, the Milan Criteria (MC), the French-AFP (F-AFP), and Metroticket 2. Read More

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Experience of cardiac implantable electronic device lead removal from a South African tertiary referral centre.

Cardiovasc J Afr 2021 Apr 19;32:1-5. Epub 2021 Apr 19.

Division of Cardiology, Department of Medicine, Faculty of Health Sciences, University of Cape Town; Cardiac Clinic, Groote Schuur Hospital, Cape Town, South Africa.

Background: The rate of cardiac implantable electronic device (CIED) implantation in low- and middle-income countries is increasing. Patients recieving these devices are frequently older and with multiple co-morbidities, which may later lead to complications requiring CIED removal. CIED removals are associated with life-threatening complications. Read More

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Impact of Advising on Total Worker Health Implementation.

J Occup Environ Med 2021 Apr 3. Epub 2021 Apr 3.

Center for Health, Work & Environment, Colorado School of Public Health, University of Colorado, Anschutz Medical Campus, 13001 E. 17 Pl., W-3111, Mail Stop B119 HSC, Aurora, CO 80045 (Tenney, Dexter, Shapiro, Dally, Brown, Schwatka, Newman), Department of Environmental and Occupational Health, Colorado School of Public Health, University of Colorado, Anschutz Medical Campus, 13001 E. 17 Pl., 3 Floor, Mail Stop B119 HSC, Aurora, CO 80045 (Tenney, Dally, Schwatka, Newman), University of Colorado School of Medicine, Adult & Child Consortium for Outcomes Research and Delivery Science (ACCORDS) Dissemination and Implementation program, Division of General Internal Medicine and Center for Women's Health Research, Anschutz Medical Campus, 12631 E. 17th Ave., Mailstop B180, Aurora, CO 80045 (Huebschmann), Principle, Workers Comp Advising LLC (McMillen), Department of Epidemiology, Colorado School of Public Health, and Division of Pulmonary Sciences and Critical Care Medicine, Department of Medicine, School of Medicine, University of Colorado, Anschutz Medical Campus, 13001 E. 17 Pl., 3 Floor, Mail Stop B119 HSC, Aurora, CO 80045 (Newman), Division of Pulmonary Sciences and Critical Care Medicine, Department of Medicine, School of Medicine, University of Colorado Anschutz Medical Campus, 13001 E. 17 Place, Mailstop B119, Aurora, CO, 80045 (Newman).

Objective: Little is understood about the mechanisms for improving the adoption and implementation of Total Worker Health® (TWH) in workplace settings. The primary objective of this study was to identify whether the delivery of TWH advising is associated with subsequent changes in TWH in small-to-medium sized businesses.

Methods: We conducted a longitudinal study of a TWH intervention in 200 organizations completing Health Links Healthy Workplace Assessments™ between October 2016 and December 2019. Read More

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Effects of preoperative serum vitamin D levels on early clinical function outcomes and the moderate-to-severe pain prevalence in postmenopausal women after primary total knee arthroplasty.

Menopause 2021 May 3. Epub 2021 May 3.

Shanghai Tenth People's Hospital Affiliated to Tongji University School of Medicine, Shanghai, China.

Objective: To investigate the impact of vitamin D levels on early clinical function outcomes and the potential risk factors of moderate-to-severe pain prevalence in postmenopausal women after primary total knee arthroplasty (TKA).

Methods: From April 2017 to December 2019, 226 women were retrospectively recruited. The women were divided into two groups based on their preoperative serum 25-hydroxyvitamin D levels: (1) vitamin D-sufficient group (≥30 ng/mL); (2) vitamin D-deficient group (<30 ng/mL). Read More

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Initial Outcomes of Transdiagnostic Internet-Delivered Cognitive Behavioral Therapy Tailored to Public Safety Personnel: Longitudinal Observational Study.

J Med Internet Res 2021 May 5;23(5):e27610. Epub 2021 May 5.

eCentreClinic, Department of Psychology, Macquarie University, Sydney, Australia.

Background: Canadian public safety personnel (PSP) experience high rates of mental health disorders and face many barriers to treatment. Internet-delivered cognitive behavioral therapy (ICBT) overcomes many such barriers, and is effective for treating depression, anxiety, and posttraumatic stress disorder (PTSD) symptoms.

Objective: This study was designed to fill a gap in the literature regarding the use of ICBT tailored specifically for PSP. Read More

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Provision of the progestogen-only pill by community pharmacies as bridging contraception for women receiving emergency contraception: the Bridge-it RCT.

Health Technol Assess 2021 May;25(27):1-92

Edinburgh Clinical Trials Unit, Usher Institute, University of Edinburgh, Edinburgh, UK.

Introduction: Unless women start effective contraception after using emergency contraception, they remain at risk of unintended pregnancy. Most women in the UK obtain emergency contraception from community pharmacies that are unable to provide ongoing contraception (apart from barrier methods which have high failure rates). This means that women need an appointment with a general practitioner or at a sexual and reproductive health clinic. Read More

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Severe Acute Respiratory Syndrome Coronavirus -2 (SARS-CoV-2): A Review on Pathophysiology, Diagnosis and Investigational Therapeutics.

Curr Med Chem 2021 May 3. Epub 2021 May 3.

University of Hradec Kralove, Faculty of Science, Department of Chemistry, Rokitanskeho 62, Hradec Kralove. Czech Republic.

There is a new public health crisis threatening the world with the emergence and spread of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The disease was later named as a novel Coronavirus disease or COVID-19. It was then declared a pandemic by the World Health Organization on March 11, 2020. Read More

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WHY DIAGNOSTIC LAPAROSCOPY.

Pol Przegl Chir 2021 Mar;93(3):1-5

Sakarya University Medical Faculty Department of General Surgery, Sakarya, Turkey.

Introduction: Abdominal pain requires rapid diagnosis and treatment, especially in emergency circumstances. Sometimes the diagnosis of the disease cannot be accomplished with laboratory and imaging methods, and an invasive procedure such as diagnostic laparoscopy may be required to obtain a diagnosis. Diagnostic laparoscopy is also performed therapeutically, but laparotomy is inevitable in some cases. Read More

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Emergency appendicectomy during COVID-19 pandemic - A single UK centre experience.

Pol Przegl Chir 2021 Mar;93(2):33-39

Department of Surgery, University Hospital North Midlands, Stoke-on-Trent, United Kingdom.

Background - In December 2019 following an outbreak of Novel coronavirus infection (COVID-19) in Wuhan, China, it spread rapidly overwhelming the healthcare systems globally. With little knowledge of COVID-19 virus, very few published reports on surgical outcomes; hospitals stopped elective surgery, whilst emergency surgery was offered only after exhausting all conservative treatment modalities. This study presents our experience of outcomes of emergency appendectomies performed during the pandemic. Read More

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Can nutraceuticals assist treatment and improve covid-19 symptoms?

Nat Prod Res 2021 May 5:1-20. Epub 2021 May 5.

Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Messina, Italy.

Viral diseases have always played an important role in public and individual health. Since December 2019, the world is facing a pandemic of SARS-CoV-2, a coronavirus that results in a syndrome known as COVID-19. Several studies were conducted to implement antiviral drug therapy, until the arrival of SARS-CoV-2 vaccines. Read More

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Coronal Compensation Mechanism of Pelvic Obliquity in Patients With Developmental Dysplasia of the Hip.

Global Spine J 2021 May 5:21925682211010760. Epub 2021 May 5.

NanKai University School of Medicine, Tianjin, China.

Study Design: Descriptive retrospective study.

Objective: DDH is a common lower limb deformity. It has been reported that this deformity can change the sagittal alignment of spine and pelvis. Read More

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Role of the Immune Microenvironment in SARS-CoV-2 Infection.

Cell Transplant 2021 Jan-Dec;30:9636897211010632

Institute of Biotechnology, National Taiwan University, Taipei, Taiwan.

Severe acute respiratory syndrome coronavirus (SARS-CoV-2) first emerged in December 2019 in Wuhan, China, and has since spread rapidly worldwide. As researchers seek to learn more about COVID-19, the disease it causes, this novel virus continues to infect and kill. Despite the socioeconomic impacts of SARS-CoV-2 infections and likelihood of future outbreaks of other pathogenic coronaviruses, options to prevent or treat coronavirus infections remain limited. Read More

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Assessing the Mortality Impact of the COVID-19 Pandemic in Florida State Prisons.

medRxiv 2021 Apr 28. Epub 2021 Apr 28.

Background: The increased risk of COVID-19 infection among incarcerated individuals due to environmental hazards is well known and recent studies have highlighted the higher rates of infection and mortality prisoners in the United States face due to COVID-19. However, the impact of COVID-19 on all-cause mortality rates in incarcerated populations has not been studied.

Methods: Using data reported by the Florida Department of Corrections on prison populations and mortality events we conducted a retrospective cohort study of all individuals incarcerated in Florida state prisons between 2015 and 2020. Read More

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Transjugular Liver Biopsy with Hemodynamic Evaluation: Correlation between Hepatic Venous Pressure Gradient and Histologic Diagnosis of Cirrhosis.

J Clin Imaging Sci 2021 26;11:25. Epub 2021 Apr 26.

Department of Radiology, NorthShore University Health Sciences, Evanston, Illinois, United States.

Objectives: Measurement of hepatic vein pressures is the accepted gold standard for the evaluation of portal hypertension. This study was conducted to evaluate the correlation between hepatic vein pressure measurements and histologic findings from transjugular liver biopsies. The hypothesis was that higher hepatic venous pressure gradients would correlate with a histologic diagnosis of cirrhosis. Read More

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Deep learning for gradability classification of handheld, non-mydriatic retinal images.

Sci Rep 2021 May 4;11(1):9469. Epub 2021 May 4.

Institute of Ophthalmology, University College London, London, EC1V 9EL, UK.

Screening effectively identifies patients at risk of sight-threatening diabetic retinopathy (STDR) when retinal images are captured through dilated pupils. Pharmacological mydriasis is not logistically feasible in non-clinical, community DR screening, where acquiring gradable retinal images using handheld devices exhibits high technical failure rates, reducing STDR detection. Deep learning (DL) based gradability predictions at acquisition could prompt device operators to recapture insufficient quality images, increasing gradable image proportions and consequently STDR detection. Read More

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Association of plasma level of high-mobility group box-1 with necroptosis and sepsis outcomes.

Sci Rep 2021 May 4;11(1):9512. Epub 2021 May 4.

Division of Pulmonary and Critical Care Medicine, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul, 06351, Republic of Korea.

The role of high-mobility group box-1 (HMGB1) in outcome prediction in sepsis is controversial. Furthermore, its association with necroptosis, a programmed cell necrosis mechanism, is still unclear. The purpose of this study is to identify the association between the plasma levels of HMGB1 and the severity and clinical outcomes of sepsis, and to examine the correlation between HMGB1 and key executors of necroptosis including receptor-interacting kinase 3 (RIPK3) and mixed lineage kinase domain-like- (MLKL) proteins. Read More

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The Columbus steerable guidewire in neurointerventions: early clinical experience and applications.

J Neurointerv Surg 2021 May 4. Epub 2021 May 4.

Department of Radiology and Nuclear Medicine, Luzerner Kantonsspital Zentrumsspital, Luzern, Switzerland.

Objective: To report our early experience in using the steerable 'Columbus' guidewire, also known as 'Drivewire' in the USA, and its potential applications in neurovascular interventions.

Methods: Neurointerventions in 36 patients (20 female, 16 male) using the steerable Columbus guidewire were recorded from August 2019 to December 2020 and included a variety of neurovascular procedures: Treatment of aneurysms (n=17), thrombectomy in acute ischemic stroke (n=12), and others (n=7), such as treatment of stenosis and embolization procedures. Immediate follow-up with digital subtraction angiography and tracking of each patient's clinical outcome was performed. Read More

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Comparative study of hospitalized children with acute respiratory distress syndrome caused by SARS-CoV-2 and influenza virus.

BMC Infect Dis 2021 May 4;21(1):412. Epub 2021 May 4.

Department of Gastrointestinal Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.

Background: Since the outbreak of coronavirus disease 2019 in December 2019, more than 8 million cases have occurred worldwide as of June 16, 2020. However, it is important to distinguish COVID-19 from other respiratory infectious diseases, such as influenza. Here, we comparatively described the clinical characteristics of children with COVID-19 and paediatric patients with influenza. Read More

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Quality of life and health status of hospitalized adults with congenital heart disease in Vietnam: a cross-sectional study.

BMC Cardiovasc Disord 2021 May 5;21(1):229. Epub 2021 May 5.

School of Medicine and Pharmacy, Vietnam National University, 144 Xuan Thuy Road, Cau Giay District, Hanoi, 100000, Vietnam.

Background: Little is known about the quality of life (QOL) and health status of adults with congenital heart disease (CHD) in developing countries. Therefore, this study aimed to describe the QOL and health status of hospitalized adults with CHD in Vietnam and investigate the association between QOL and their biological-social characteristics.

Methods: A cross-sectional study was conducted with 109 adults with CHD, hospitalized in the Vietnam National Heart Institute, between June and December 2019. Read More

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Health Resource and Cost Savings Achieved in a Multidisciplinary Lung Cancer Clinic.

Curr Oncol 2021 Apr 29;28(3):1681-1695. Epub 2021 Apr 29.

Department of Medicine, Queen's University, Kingston, ON K7L 5P9, Canada.

: Lung cancer (LC) care is resource and cost intensive. We launched a Multidisciplinary LC Clinic (MDC), where patients with a new LC diagnosis received concurrent oncology consultation, resulting in improved time to LC assessment and treatment. Here, we evaluate the impact of MDC on health resource utilization, patient and caregiver costs, and secondary patient benefits. Read More

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ACE2 Is an Adjacent Element of Atherosclerosis and COVID-19 Pathogenesis.

Int J Mol Sci 2021 Apr 29;22(9). Epub 2021 Apr 29.

Institute for Atherosclerosis Research, Skolkovo Innovative Center, 121609 Moscow, Russia.

COVID-19 is a highly contagious new infection caused by the single-stranded RNA Sars-CoV-2 virus. For the first time, this infection was recorded in December 2019 in the Chinese province of Wuhan. The virus presumably crossed the interspecies barrier and passed to humans from a bat. Read More

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