3,522 results match your criteria days ecmo


Two Consecutive Runs of Veno-Venous Extracorporeal Membrane Oxygenation in a Peripartum Patient with COVID-19 Acute Respiratory Distress Syndrome.

Case Rep Crit Care 2021 9;2021:2032197. Epub 2021 Jul 9.

Department of Medicine (DIMED), Padua University School of Medicine, Italy.

Veno-venous extracorporeal membrane oxygenation (V-V ECMO) may be required to treat critically ill patients with COVID-19-associated severe acute respiratory distress syndrome (ARDS). We report the case of a 43-year-old peripartum patient, who underwent two sequential V-V ECMO runs. The first extracorporeal support was established for COVID-19 ARDS, as characterized by severe hypoxemia and hypercapnia (arterial partial pressure of oxygen to inspired oxygen fraction ratio 85 mmHg and arterial partial pressure of carbon dioxide 95 mmHg) and reduction of respiratory system static compliance to 25 mL/cmHO, unresponsive to mechanical ventilation and prone positioning. Read More

View Article and Full-Text PDF

Six-Month Pulmonary Function After Venovenous Extracorporeal Membrane Oxygenation for Coronavirus Disease 2019 Patients.

Crit Care Explor 2021 Jul 16;3(7):e0494. Epub 2021 Jul 16.

Department of Critical Care, Centres Hospitaliers Jolimont, La Louvière, Belgium.

Objectives: Venovenous extracorporeal membrane oxygenation has been largely used in patients with refractory acute respiratory distress syndrome due to coronavirus disease 2019. Few data on long-term pulmonary function among venovenous extracorporeal membrane oxygenation survivors are available.

Design: Retrospective, observational cohort. Read More

View Article and Full-Text PDF

Pica (Allotriophagy): An Underestimated Risk Factor for Severe Leptospirosis (Weil's Diseases)? Report of a Leptospira Septic Shock Successfully Managed with ECMO.

Infect Dis Rep 2021 Jul 5;13(3):619-626. Epub 2021 Jul 5.

Clinical Department of Medical, Surgical and Health Sciences, University of Trieste, Cattinara University Hospital, 34148 Trieste, Italy.

Leptospirosis is a zoonosis caused by infection with pathogenic strains of the bacterium Leptospira. The disease can be complicated by pulmonary hemorrhages and acute respiratory distress syndrome, with the mortality rate increasing to 51-100%. We report the case of a 37-year-old man who was admitted to the emergency department with a 6-day history of fever, weakness, vomiting and diarrhea, followed by jaundice. Read More

View Article and Full-Text PDF

Physical Therapy and Sedation While on Extracorporeal Membrane Oxygenation for COVID-19-Associated Acute Respiratory Distress Syndrome.

J Cardiothorac Vasc Anesth 2021 Jun 29. Epub 2021 Jun 29.

Department of Medicine, Division of Critical Care Medicine, Mayo Clinic, Jacksonville, FL.

Objectives: This study aimed to determine whether patients on extracorporeal membrane oxygenation (ECMO) with coronavirus disease 2019 (COVID-19) achieved lower rates of physical therapy participation and required more sedation than those on ECMO without COVID-19.

Design: Retrospective, observational, matched-cohort study.

Setting: Bicenter academic quaternary medical centers. Read More

View Article and Full-Text PDF

Lung transplantation using allografts with more than 8 hours of ischemic time: A single-institution experience.

J Heart Lung Transplant 2021 Jun 23. Epub 2021 Jun 23.

Division of Cardiovascular and Thoracic Surgery, Department of Surgery, Duke University Medical Center, Durham, North Carolina.

Background: Six hours was historically regarded as the limit of acceptable ischemic time for lung allografts. However, broader sharing of donor lungs often necessitates use of allografts with ischemic time >6 hours. We characterized the association between ischemic time ≥8 hours and outcomes after lung transplantation using a contemporary cohort from a high-volume institution. Read More

View Article and Full-Text PDF

Outcomes of extracorporeal life support for respiratory failure in children with primary immunodeficiencies.

Perfusion 2021 Jul 19:2676591211033946. Epub 2021 Jul 19.

The Heart Institute, Cincinnati Children's Hospital Medical Center, Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA.

Objective: Extracorporeal Membrane Oxygenation (ECMO) may serve as a life-saving rescue therapy in critically ill children with respiratory failure. While survival rates of ECMO in children with secondary immunodeficiency is considered relatively poor, survival rates in children with primary immunodeficiencies (PID) has yet to be thoroughly investigated.

Design: Retrospective analysis of prospectively collected data from children (29 days-18 years old). Read More

View Article and Full-Text PDF

Transition to Ductal Stenting for Single Ventricle Patients Led to Improved Survival: An Institutional Case Series.

World J Pediatr Congenit Heart Surg 2021 Jul;12(4):518-526

Congenital Heart Surgery Research and Training Program, 22957Duke University Medical Center, Durham, NC, USA.

Background: The use of systemic-to-pulmonary shunts (SPS) in neonates with single ventricle heart defects and ductal-dependent pulmonary blood flow (ddPBF) was historically associated with high morbidity and mortality at our center. As a result, we transitioned to the preferential use of ductus arteriosus stents (DS) when feasible. This report describes our initial results with this strategy. Read More

View Article and Full-Text PDF

Use of Transcarotid IMPELLA 2.5 Axial-Flow Pump Device for Left Ventricle Unloading During VA-ECMO Support in Pediatric Acute Heart Failure.

World J Pediatr Congenit Heart Surg 2021 Jul;12(4):542-546

Department of Pediatric Cardiology and Cardiac Surgery, 9342Bambino Gesù Children Hospital IRCS, Rome, Italy.

An alternative strategy for left ventricular (LV) venting during short-term mechanical circulatory support is use of Impella axial-flow pump. We present our transcarotid Impella 2.5 implantation technique using a polytetrafluoroethylene graft, in two children with acute heart failure treated primarily with venoarterial ECMO. Read More

View Article and Full-Text PDF

Liver Dysfunction Associated With In-Hospital Mortality in Adult Extracorporeal Membrane Oxygenation Support.

Crit Care Explor 2021 Jul 13;3(7):e0484. Epub 2021 Jul 13.

Department of Cardiovascular and Thoracic Surgery, Rush University Medical Center, Chicago, IL.

Extracorporeal membrane oxygenator support is a powerful clinical tool that is currently enjoying a resurgence in popularity. Wider use of extracorporeal membrane oxygenator support is limited by its significant risk profile and extreme consumption of resources. This study examines the role of markers of liver dysfunction in predicting outcomes of adult patients requiring extracorporeal membrane oxygenator support. Read More

View Article and Full-Text PDF

Use of rotational thromboelastometry to predict hemostatic complications in pediatric patients undergoing extracorporeal membrane oxygenation: A retrospective cohort study.

Res Pract Thromb Haemost 2021 Jul 14;5(5):e12553. Epub 2021 Jul 14.

Department of Pediatric Hematology Erasmus Medical Center - Sophia Children's Hospital Rotterdam The Netherlands.

Background: The incidence of hemostatic complications in pediatric patients undergoing extracorporeal membrane oxygenation (ECMO) is high. The optimal anticoagulation strategy in children undergoing ECMO is unknown.

Objectives: To study the association between hemostatic complications, coagulation tests, and clinical parameters in pediatric patients undergoing ECMO and their effect on survival. Read More

View Article and Full-Text PDF

Minimal invasive temporary percutaneous right ventricular circulatory support after left ventricular assist device implantation.

Interact Cardiovasc Thorac Surg 2021 Jul 16. Epub 2021 Jul 16.

Department of Cardiothoracic, Transplantation and Vascular Surgery, Hannover Medical School, Hannover, Germany.

Objectives: Cardiogenic shock is a life-threatening situation with high mortality rates. Mechanical unloading of the left ventricle may be achieved via left ventricular assist device (LVAD) implantation. Postoperative right ventricular (RV) failure, however, has very limited therapeutic options and is associated with increased postoperative mortality. Read More

View Article and Full-Text PDF

Seizures in Children with Cardiac Disease on Extracorporeal Membrane Oxygenation.

Neurocrit Care 2021 Jul 15. Epub 2021 Jul 15.

Division of Pediatric Critical Care Medicine, Department of Pediatrics, Indiana University School of Medicine and Riley Hospital for Children at Indiana University Health, 705 Riley Hospital Drive, Phase 2, Room 4900, Indianapolis, IN, 46202-5225, USA.

Background: Children supported with extracorporeal membrane oxygenation (ECMO) have been shown to be at risk for developing seizures. However, previous studies have consisted of heterogeneous patient populations. We aimed to describe the rate of seizures in pediatric patients receiving ECMO for cardiac indications and to identify risk factors for the occurrence of this complication. Read More

View Article and Full-Text PDF

Emergency sandwich patch repair right ventricular incision for postinfarction ventricular septal defects: a case series.

Eur Heart J Case Rep 2021 May 17;5(5):ytab141. Epub 2021 May 17.

Department of Cardiovascular Surgery, National Cerebral and Cardiovascular Center, 6-1 Kishibe-Shimmachi, Suita, Osaka 564-8565, Japan.

Background: The surgical treatment for postinfarction ventricular septal defect (VSD) remains challenging, especially in emergency cases. Several authors have reported the efficacy of a sandwich patch VSD repair a right ventricular (RV) incision. However, this procedure remains uncommon, and its efficacy is still unknown, especially when performed under an emergency. Read More

View Article and Full-Text PDF

Recurrent massive pulmonary embolism following catheter directed thrombolysis in a 21-year-old with COVID-19: a case report.

Eur Heart J Case Rep 2021 Apr 30;5(4):ytab140. Epub 2021 Apr 30.

Department of Cardiology, Keck School of Medicine of USC, Division of Cardiovascular Medicine, 1510 San Pablo Street, Suite 322, Los Angeles, CA 90033, USA.

Background: Coronavirus Disease-2019 (COVID-19) has been associated with increased incidence of pulmonary embolism (PE), even among patients at low risk for venous thrombo-embolic (VTE) events.

Case Summary: We present the case of a 21-year-old male, with no previous medical history, who presented with cough, fevers, shortness of breath, pleuritic chest pain, and 1 day of dizziness with near syncope as well as acutely worsened dyspnoea. He was subsequently diagnosed with COVID-19 and massive PE. Read More

View Article and Full-Text PDF

A case report about successful treatment of refractory ventricular tachycardia with ablation under prolonged haemodynamic support with extracorporeal membrane oxygenation.

Eur Heart J Case Rep 2021 Mar 10;5(3):ytab084. Epub 2021 Mar 10.

Department of Medicine, Solna Karolinska University Hospital D1:04, 171 76 Stockholm, Sweden.

Background: In patients with severe left ventricular dysfunction, recurrent ventricular tachycardia (VT) non-responsive to antiarrhythmic therapies may cause further deterioration of cardiac function and haemodynamic instability. The use of extracorporeal membrane oxygenation (ECMO) in the setting of haemodynamically unstable VT may allow rhythm stabilization and can be effective in providing haemodynamic stability during VT ablation procedures.

Case Summary: We describe the clinical course of a patient with ischaemic cardiomyopathy and recurrent VTs in the early post-myocardial infarction (MI) period. Read More

View Article and Full-Text PDF

Weekend effect in extracorporeal membrane oxygenation therapy initiation: a nationwide cohort study in South Korea.

Ann Transl Med 2021 May;9(9):742

Department of Anesthesiology and Pain Medicine, Seoul National University Bundang Hospital, Seongnam, South Korea.

Background: Extracorporeal membrane oxygenation (ECMO) therapy requires close monitoring and optimal management after initiation. However, it remains unclear whether the day of the week of ECMO initiation affects patient outcomes. We aimed to investigate whether the initiation of ECMO therapy during a weekend was associated with increased mortality risk. Read More

View Article and Full-Text PDF

Management of a COVID-19-infected critically ill patient treated by extracorporeal membrane oxygenation: a case report.

Ann Palliat Med 2021 Jul 1. Epub 2021 Jul 1.

State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, the First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.

Coronavirus disease 2019 (COVID-19) is a new type of respiratory infectious disease that spreads among humans. People infected with COVID-19 present with severe acute respiratory symptoms, fever, cough, breathlessness and dyspnea, impaired physical conditions, kidney failure, and even death. Chest radiographs suggest diffuse inflammation in both lungs and show "white lung" changes. Read More

View Article and Full-Text PDF

Limb Amputation Following Extracorporeal Membrane Oxygenation Therapy Among Survivors: A Nationwide Cohort Study from South Korea.

ASAIO J 2021 Jul 8. Epub 2021 Jul 8.

From the Department of Cardiology, Cardiovascular Center, Seoul National University Bundang Hospital, Seongnam, South Korea Department of Anesthesiology and Pain Medicine, Seoul National University Bundang Hospital, Seongnam, South Korea.

We aimed to investigate the incidence of limb amputation due to vascular complications related to extracorporeal membrane oxygenation (ECMO) therapy among survivors and examine its association with long-term mortality in these cases. Data from the National Health Insurance Service database in South Korea were extracted for this population-based cohort study. Adult people who underwent ECMO therapy between 2005 and 2018 were included. Read More

View Article and Full-Text PDF

Prone-Positioning for Severe Acute Respiratory Distress Syndrome Requiring Extracorporeal Membrane Oxygenation.

Crit Care Med 2021 Jul 14. Epub 2021 Jul 14.

Service de Médecine Intensive-Réanimation, Institut de Cardiologie, APHP, Sorbonne Université Hôpital Pitié-Salpêtrière, Paris, France. SAMOVAR, Telecom SudParis, Institut Polytechnique de Paris, Evry, France. Service de Radiologie, APHP, Université de Paris, Hôpital Bichat-Claude-Bernard, Paris, France. Université de Picardie Jules Verne, Amiens, France. Sorbonne Université, INSERM, UMRS_1166-ICAN, Institute of Cardiometabolism and Nutrition, Paris, France. Service de Chirurgie Cardiaque, Institut de Cardiologie, APHP, Sorbonne Université Hôpital Pitié-Salpêtrière, Paris, France.

Objectives: To determine the characteristics and outcomes of patients prone-positioned during extracorporeal membrane oxygenation for severe acute respiratory distress syndrome and lung CT pattern associated with improved respiratory system static compliance after that intervention.

Design: Retrospective, single-center study over 8 years.

Settings: Twenty-six bed ICU in a tertiary center. Read More

View Article and Full-Text PDF

Lung transplantation for acute respiratory distress syndrome: A multicenter experience.

Am J Transplant 2021 Jul 13. Epub 2021 Jul 13.

Department of Thoracic Surgery, Medical University of Vienna, Vienna, Austria.

Acute respiratory distress syndrome (ARDS) is a rapidly progressive lung disease with a high mortality rate. Although lung transplantation (LTx) is a well-established treatment for a variety of chronic pulmonary diseases, LTx for acute lung failure (due to ARDS) remains controversial. We reviewed posttransplant outcome of ARDS patients from three high-volume European transplant centers. Read More

View Article and Full-Text PDF

A successful daptomycin and micafungin dosing strategy in veno-venous ECMO and continuous renal replacement.

J Clin Pharm Ther 2021 Jul 13. Epub 2021 Jul 13.

Division of Pulmonary Critical Care, University of New Mexico Health Sciences Center, Albuquerque, New Mexico, USA.

What Is Known And Objective: Studies have demonstrated that ECMO leads to pharmacokinetic changes, with alterations in volume of distribution, clearance and drug sequestration by the circuit. We describe a successful dosing approach for daptomycin and micafungin for the treatment of VRE faecium bacteremia and C. glabrata fungemia in a patient receiving veno-venous ECMO and CRRT. Read More

View Article and Full-Text PDF

Outcomes of adult patients supported by extracorporeal membrane oxygenation (ECMO) following cardiopulmonary arrest. The Mayo Clinic experience.

J Card Surg 2021 Jul 11. Epub 2021 Jul 11.

Department of Anesthesiology and Perioperative Medicine, Mayo Clinic, Rochester, MN, USA.

Introduction: To describe our experience in use of extracorporeal life support (ECLS) as a rescue strategy in patients following cardiopulmonary resuscitation.

Methods: A retrospective analysis was performed for patients (n = 101) who received ECLS after cardiorespiratory arrest between May 2001 and December 2014. The primary outcome was survival to hospital discharge. Read More

View Article and Full-Text PDF

Clinical efficacy of direct or indirect left ventricular unloading during venoarterial extracorporeal membrane oxygenation for primary cardiogenic shock.

J Thorac Cardiovasc Surg 2021 Jun 18. Epub 2021 Jun 18.

Division of Cardiothoracic and Vascular Surgery, Department of Surgery, Columbia University Medical Center, New York, NY. Electronic address:

Objective: Left ventricular (LV) distention is a feared complication in patients receiving venoarterial (VA) extracorporeal membrane oxygenation (ECMO). LV unloading can be achieved indirectly with intra-aortic balloon pump (IABP) or directly with an Impella device (Abiomed, Danvers, Mass). We sought to assess the clinical and hemodynamic effects of IABP and Impella devices on patients supported with VA ECMO. Read More

View Article and Full-Text PDF

Multi-institutional Analysis of 200 COVID-19 Patients treated with ECMO:Outcomes and Trends.

Ann Thorac Surg 2021 Jul 6. Epub 2021 Jul 6.

West Virginia University, Morgantown, WV.

Background: The role of ECMO in the management of patients with COVID-19 continues to evolve. The purpose of this manuscript is to review a multi-institutional clinical experience in 200 consecutive patients at 29 hospitals with confirmed COVID-19 supported with ECMO.

Methods: This analysis includes our first 200 COVID-19 patients with complete data who were supported with and separated from ECMO. Read More

View Article and Full-Text PDF

Diagnostic yield of routine daily blood culture in patients on veno-arterial extracorporeal membrane oxygenation.

Crit Care 2021 07 8;25(1):241. Epub 2021 Jul 8.

Service d'Anesthésie-Réanimations Chirurgicales, DMU CARE, DHU A-TVB, Assistance Publique-Hôpitaux de Paris (AP-HP), Hôpitaux Universitaires Henri Mondor, 1 rue Gustave Eiffel, 94000, Créteil, France.

Background: Bloodstream infections (BSIs) are frequent on veno-arterial extracorporeal membrane oxygenation (V-A ECMO). Performing routine blood cultures (BCs) may identify early paucisymptomatic BSIs. We investigated the contribution of systematic daily BCs to detect BSIs on V-A ECMO. Read More

View Article and Full-Text PDF

Tracheostomy management in patients with severe acute respiratory distress syndrome receiving extracorporeal membrane oxygenation: an International Multicenter Retrospective Study.

Crit Care 2021 07 7;25(1):238. Epub 2021 Jul 7.

Department of Medicine, Columbia University College of Physicians & Surgeons, New York, NY, USA.

Background: Current practices regarding tracheostomy in patients treated with extracorporeal membrane oxygenation (ECMO) for acute respiratory distress syndrome are unknown. Our objectives were to assess the prevalence and the association between the timing of tracheostomy (during or after ECMO weaning) and related complications, sedative, and analgesic use.

Methods: International, multicenter, retrospective study in four large volume ECMO centers during a 9-year period. Read More

View Article and Full-Text PDF

Importance of critical care staffing and standard intensive care therapy in the COVID-19 era: a descriptive study of the first epidemic wave at a Swiss tertiary intensive care unit.

Swiss Med Wkly 2021 06 25;151:w20529. Epub 2021 Jun 25.

Department of Intensive Care Medicine, Bern University Hospital, Inselspital, University of Bern, Switzerland.

Aim: Mortality rates of COVID-19 patients hospitalised in intensive care units (ICUs) are generally high. Availability of ICU resources might influence clinical outcomes. The aim of this study was to examine the clinical course of the 42 patients treated during the first epidemic wave between 2 March and 20 May 2020 at the tertiary ICU of the Bern University Hospital, where staffing, equipment and drugs were not limited. Read More

View Article and Full-Text PDF

Chronic respiratory disease and survival outcomes after extracorporeal membrane oxygenation.

Respir Res 2021 Jul 5;22(1):195. Epub 2021 Jul 5.

Department of Anesthesiology and Pain Medicine, Seoul National University Bundang Hospital, Gumi-ro, 173, Beon-gil, Bundang-gu, Seongnam, 13620, South Korea.

Background: Quality of life following extracorporeal membrane oxygenation (ECMO) therapy is an important health issue. We aimed to describe the characteristics of patients who developed chronic respiratory disease (CRD) following ECMO therapy, and investigate the association between newly diagnosed post-ECMO CRDs and 5-year all-cause mortality among ECMO survivors.

Methods: We analyzed data from the National Health Insurance Service in South Korea. Read More

View Article and Full-Text PDF

Anticoagulation therapy using unfractionated heparin at a therapeutic dose for coronavirus disease 2019 patients with severe pneumonia: a retrospective historical control study.

Acute Med Surg 2021 Jan-Dec;8(1):e679. Epub 2021 Jun 30.

Trauma and Acute Critical Care Center Tokyo Medical and Dental University Hospital of Medicine Tokyo Japan.

Aim: Patients with severe coronavirus disease 2019 (COVID-19) pneumonia often have complications of coagulopathy and thrombotic phenomena, which lead to high mortality. Whether administering systematic anticoagulant therapy is beneficial remains unclear. We report our experience using systemic anticoagulation with unfractionated heparin to treat severe COVID-19. Read More

View Article and Full-Text PDF

Hemoadsorption for management of patients on veno-venous ECMO support for severe COVID-19 acute respiratory distress syndrome.

J Card Surg 2021 Jul 4. Epub 2021 Jul 4.

Department of Cardiothoracic Surgery, New York University Langone Health, New York, New York, USA.

Background And Aim: Patients with severe coronavirus disease 2019 (COVID-19) develop a profound cytokine-mediated pro-inflammatory response. This study reports outcomes in 10 patients with COVID-19 supported on veno-venous extracorporeal membrane oxygenation (VV-ECMO) who were selected for the emergency use of a hemoadsorption column integrated in the ECMO circuit.

Materials And Methods: Pre and posttreatment, clinical data, and inflammatory markers were assessed to determine the safety and feasibility of using this system and to evaluate the clinical effect. Read More

View Article and Full-Text PDF