7,300 results match your criteria database hypothesis


Inheritance of seedlessness and the molecular characterization of the INO gene in Annonaceae.

Braz J Biol 2021 21;83:e246455. Epub 2021 Jun 21.

Universidade Federal de Minas Gerais - UFMG, Instituto de Ciências Agrárias, Montes Claros, MG, Brasil.

The inheritance of the seedless fruit characteristic of Annona squamosa has not yet been explained. Molecular techniques may aid breeding programs, mainly in the assisted selection of the target gene. The INO gene may be related to seed development in these fruits. Read More

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Socioeconomic Status and Survival in Nasopharyngeal Carcinoma: A Population-Based Study.

Laryngoscope 2021 Jun 23. Epub 2021 Jun 23.

Department of Otolaryngology-Head and Neck Surgery, Tulane University School of Medicine, New Orleans, Louisiana, U.S.A.

Objectives/hypothesis: To evaluate survival for nasopharyngeal carcinoma in relation to socioeconomic status.

Study Design: Retrospective cohort study using the Surveillance, Epidemiology, and End Results (SEER) Census Tract-level Socioeconomic Status Database (2000-2016).

Methods: Patients with nasopharyngeal carcinoma diagnosed between 2000 and 2016 were identified. Read More

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Imaging Modalities for the Glenoid Track in Recurrent Shoulder Instability: A Systematic Review.

Orthop J Sports Med 2021 Jun 3;9(6):23259671211006750. Epub 2021 Jun 3.

Steadman Philippon Research Institute, Vail, Colorado, USA.

Background: The glenoid track (GT) concept illustrates how the degree of glenoid bone loss and humeral bone loss in the glenohumeral joint can guide further treatment in a patient with anterior instability. The importance of determining which lesions are at risk for recurrent instability involves imaging of the glenohumeral joint, but no studies have determined which type of imaging is the most appropriate.

Purpose/hypothesis: The purpose of this study was to determine the validity and accuracy of different imaging modalities for measuring the GT in shoulders with recurrent anterior instability. Read More

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Construction and analysis of a ceRNA network and patterns of immune infiltration in bladder cancer.

Transl Androl Urol 2021 May;10(5):1939-1955

Department of Urology, The First Hospital of China Medical University, Shenyang, China.

Background: Bladder cancer (BC) is the ninth most common malignant tumor, accounting for an estimate of 549,000 new BC cases and 200,000 BC-related deaths worldwide in 2018. The prognosis of BC has not substantially improved despite significant advances in the diagnosis and treatment of the disease.

Methods: The RNA sequencing (RNA-seq) data and clinical information of BC patients were downloaded from The Cancer Genome Atlas (TCGA) database. Read More

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The Geographic Distribution of Videolaryngostroboscopy in the United States.

J Voice 2021 Jun 20. Epub 2021 Jun 20.

Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland.

Purpose: To study the geographic utilization of videolaryngostroboscopy (VLS) with the hypothesis that office-based voice care is unevenly distributed across the United States.

Materials And Methods: This is a cross-sectional database analysis of Medicare beneficiaries. The Centers for Medicare and Medicaid Services Provider Utilization and Payment Data Physician and Other Supplier Public Use File from 2012 to 2017 was analyzed to evaluate VLS utilization. Read More

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Absence of fetal heart rate cycling on the intrapartum cardiotocograph (CTG) is associated with intrapartum pyrexia and lower Apgar scores.

J Matern Fetal Neonatal Med 2021 Jun 22:1-6. Epub 2021 Jun 22.

Global Academy of Medical Education and Training, London, UK.

Background: Cycling consists of alternating periods of reduced and normal fetal heart variability, reflecting changes in fetal behavioral states. Occurrence of active and quiet sleep cycles is considered to be a hallmark of fetal autonomic nervous system integrity, demonstrating healthy interaction between the parasympathetic and sympathetic nervous systems. Cycling is an overlooked feature in most international cardiotocography (CTG) guidelines. Read More

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Brain-based sex differences in autism spectrum disorder across the lifespan: A systematic review of structural MRI, fMRI, and DTI findings.

Neuroimage Clin 2021 Jun 9;31:102719. Epub 2021 Jun 9.

College of Health Solutions, Arizona State University, 975 S. Myrtle Ave, Tempe, AZ 85281, USA. Electronic address:

Females with autism spectrum disorder (ASD) have been long overlooked in neuroscience research, but emerging evidence suggests they show distinct phenotypic trajectories and age-related brain differences. Sex-related biological factors (e.g. Read More

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A comprehensive review on the analytical method, occurrence, transformation and toxicity of a reactive pollutant: BADGE.

Environ Int 2021 Jun 17;155:106701. Epub 2021 Jun 17.

School of Civil and Environmental Engineering, Nanyang Technological University, Singapore 639798, Singapore; Nanyang Environment & Water Research Institute, Nanyang Technological University, Singapore 637141, Singapore. Electronic address:

Bisphenol A diglycidyl ether (BADGE)-based epoxy resin is one of the most widely used epoxy resins with an annual production amount of several million tons. Compared with all other legacy or emerging organic compounds, BADGE is special due to its toxicity and high reactivity in the environment. More and more studies are available on its analytical methods, occurrence, transformation and toxicity. Read More

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Need satisfaction in intergroup contact: A multinational study of pathways toward social change.

J Pers Soc Psychol 2021 Jun 17. Epub 2021 Jun 17.

Department of Psychology, University of Groningen.

What role does intergroup contact play in promoting support for social change toward greater social equality? Drawing on the needs-based model of reconciliation, we theorized that when inequality between groups is perceived as illegitimate, disadvantaged group members will experience a need for empowerment and advantaged group members a need for acceptance. When intergroup contact satisfies each group's needs, it should result in more mutual support for social change. Using four sets of survey data collected through the Zurich Intergroup Project in 23 countries, we tested several preregistered predictions, derived from the above reasoning, across a large variety of operationalizations. Read More

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Exploring public sentiment on enforced remote work during COVID-19.

J Appl Psychol 2021 Jun;106(6):797-810

Department of Psychology.

Due to the coronavirus disease 2019 (COVID-19) pandemic, many employees have been strongly encouraged or mandated to work from home. The present study sought to understand the attitudes and experiences of the general public toward remote work by analyzing Twitter data from March 30 to July 5 of 2020. We web scraped over 1 million tweets using keywords such as "telework," "work from home," "remote work," and so forth, and analyzed the content using natural language processing (NLP) techniques. Read More

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Anger regulation choice-The role of age and habitual reappraisal.

Emotion 2021 Jun 17. Epub 2021 Jun 17.

Department of Neurology, Max Planck Institute for Human Cognitive and Brain Sciences.

The ability to choose emotion regulation strategies in accordance to contextual demands, known as emotion regulation flexibility, is key to healthy adaptation. While recent investigations on spontaneous emotion regulation choice tested the effects of emotional intensity and age using standardized negative pictures with no particular emotional quality, we elicited the discrete emotion of anger with personally relevant autobiographical memories in a sample of 52 younger and 41 older adults. In addition, we included habitual reappraisal as a predictor of emotion regulation choice. Read More

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Early Discharge after Lobectomy for Lung Cancer does not Equate to Early Readmission.

Ann Thorac Surg 2021 Jun 11. Epub 2021 Jun 11.

Division of Thoracic Surgery, Department of Cardiothoracic Surgery, Stanford University School of Medicine, Stanford, CA; VA Palo Alto Health Care System, Palo Alto, CA. Electronic address:

Background: Enhanced recovery after surgery (ERAS) pathways in several specialties reduce length of stay, but accelerated discharge after thoracic surgery is not well characterized. This study tested the hypothesis that patients discharged on post-operative day 1 (POD1) after lobectomy for lung cancer have an increased risk of readmission.

Methods: Patients who underwent a lobectomy for lung cancer between 2011-2019 in the American College of Surgeons National Surgical Quality Improvement Program database were identified. Read More

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A new hypothesis linking oxytocin to menstrual migraine.

Headache 2021 Jun 14. Epub 2021 Jun 14.

Department of Anesthesiology, Perioperative and Pain Medicine, School of Medicine, Stanford University, Stanford, CA, USA.

Objective: To highlight the emerging understanding of oxytocin (OT) and oxytocin receptors (OTRs) in modulating menstrual-related migraine (MRM).

Background: MRM is highly debilitating and less responsive to therapy, and attacks are of longer duration than nonmenstrually related migraine. A clear understanding of the mechanisms underlying MRM is lacking. Read More

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Factors Associated With Unanticipated Admission After Outpatient Endoscopic Sinonasal Surgery.

Laryngoscope 2021 Jun 14. Epub 2021 Jun 14.

Department of Otolaryngology - Head and Neck Surgery, Rutgers New Jersey Medical School, Newark, New Jersey, U.S.A.

Objectives/hypothesis: To identify factors that may increase the risk of unplanned admission following elective outpatient endoscopic sinonasal surgery (ESS).

Study Design: Retrospective analysis of the National Surgical Quality Improvement Program (NSQIP).

Methods: All cases of ESS were extracted from the 2010 to 2018 NSQIP database using Current Procedural Terminology codes. Read More

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Outcomes of pregnancy and delivery in women with continent lower urinary tract reconstruction: systematic review of the literature.

Int Urogynecol J 2021 Jun 14. Epub 2021 Jun 14.

Department of Urology, CHU-Université de Nantes, 1 place Alexis Ricordeau, 44000, Nantes, France.

Introduction And Hypothesis: The aim of this systematic review of the literature was to pool all the existing data regarding pregnancy and delivery in women with neurogenic bladder or bladder exstrophy who had undergone previous lower urinary tract reconstruction (LUTR).

Methods: We conducted a systematic review of the literature from PubMed/MedLine, ClinicalTrials.gov and the Google Scholar database, from 1972 to July 2020. Read More

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Young age at diabetes diagnosis amplifies the effect of diabetes duration on risk of chronic kidney disease: a prospective cohort study.

Diabetologia 2021 Jun 14. Epub 2021 Jun 14.

Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong, Special Administrative Region, People's Republic of China.

Aims/hypothesis: We postulated that the increased lifetime risk of chronic kidney disease (CKD) in young-onset diabetes is attributable to both long disease duration and more aggressive disease. We examined whether age at diabetes diagnosis modifies the effect of diabetes duration on risk of CKD.

Methods: We included 436,744 people with incident type 2 diabetes in the Hong Kong Diabetes Surveillance Database (HKDSD) and 16,979 people with prevalent type 2 diabetes in the Hong Kong Diabetes Register (HKDR). Read More

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Exploration of spatial distribution of brain metastasis from small cell lung cancer and identification of metastatic risk level of brain regions: a multicenter, retrospective study.

Cancer Imaging 2021 Jun 13;21(1):41. Epub 2021 Jun 13.

Suzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, 88 Keling Road, Suzhou New District, Suzhou, 215163, Jiangsu, China.

Objectives: This study aimed to explore the spatial distribution of brain metastases (BMs) from small cell lung cancer (SCLC) a homogenous sample, and to identify the metastatic risk levels in brain regions.

Methods: T1-enhanced magnetic resonance imaging (MRI) from SCLC patients were retrospectively reviewed from three medical institutions in China. All images were registered to the standard brain template provided by the Montreal Neurological Institute (MNI) 152 database, followed by transformation of the location of all BMs to the space of standard brain. Read More

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Impact of A1 Asymmetry on the Woven EndoBridge Device in Anterior Communicating Artery Aneurysms.

AJNR Am J Neuroradiol 2021 Jun 11. Epub 2021 Jun 11.

Department of Interventional Neuroradiology (J. Cortese, J. Caroff, J.-B.G., C.M., G.A., A.E., L.I., S.G., A.O., V.C., J.M., L.S.), NEURI Brain Vascular Center, Bicêtre Hospital, APHP, Paris Saclay University, Le Kremlin-Bicêtre, France.

Background And Purpose: Woven EndoBridge (WEB) devices are increasingly used to treat intracranial aneurysms. A1 asymmetry contributes to anterior communicating artery aneurysm formation and to treatment instability after coiling. We sought to evaluate whether A1 asymmetry had an impact on angiographic outcome in anterior communicating artery aneurysms treated with the WEB. Read More

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A comprehensive dataset of histopathology images, grades and patient demographics for human Osteoarthritis Cartilage.

Data Brief 2021 Aug 14;37:107129. Epub 2021 May 14.

Department of Biomedical Engineering, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195, USA.

Osteoarthritis (OA) is a leading cause of disability in older adults and takes substantial toll at personal, economic and societal levels. There is inadequate comprehension of OA disease progression specifically during the early phases of OA. This knowledge is critical to understanding the heterogeneity in OA progression as well as enable development of targeted therapeutics at the start of the disease rather than end-stage. Read More

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Quality of life, emotion regulation, and dissociation: Evaluating unique relations in an undergraduate sample and probable PTSD subsample.

Psychol Trauma 2021 Jun 10. Epub 2021 Jun 10.

Department of Psychology, Binghamton University (SUNY).

Objective: Previous research has documented a strong association between emotion regulation (ER) and quality of life (QoL). Nevertheless, extant studies have not tested this association in participants meeting diagnostic criteria for posttraumatic stress disorder nor accounted for other explanatory variables statistically. Our primary objective was to evaluate the unique relations among ER dimensions and QoL while controlling for dissociation, neuroticism, and PTSD symptoms statistically. Read More

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Spontaneous mental replay of music improves memory for incidentally associated event knowledge.

J Exp Psychol Gen 2021 Jun 10. Epub 2021 Jun 10.

Department of Psychology.

Why is music effective at evoking memories from one's past? Familiar music is a potent cue that can trigger, often involuntarily, the recollection of associated autobiographical memories. The mechanisms by which associations between music and nonmusical knowledge initially form and consolidate into long-term memory have not been elucidated. In three experiments, we linked two common musical phenomena, involuntary musical imagery (INMI; commonly called "earworms") and music-evoked remembering, in testing the hypothesis that such imagery aids in the consolidation of memory for events with which music becomes associated. Read More

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Evidence from an fMRI study that dessert-flavored e-cigarettes engage taste-related, but not smoking-related, brain circuitry for female daily smokers.

Exp Clin Psychopharmacol 2021 Jun 10. Epub 2021 Jun 10.

Department of Neurosurgery.

Regulations limiting the sale of flavored e-cigarette products are controversial for their potential to interfere with e-cigarette use as a cessation aid in addition to curbing youth use. Limited research suggests that flavor might enhance the addictive potential of e-cigarettes; however, the acute effects of flavored aerosols on brain function among humans have not been assessed. The present study aimed to isolate and compare the neural substrates of flavored and unflavored e-cigarette aerosols on brain function among nine female daily smokers. Read More

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Real-time momentary mood as a predictor of college students' prescription drug misuse in daily life: Direct links and the moderating role of background mental health.

Exp Clin Psychopharmacol 2021 Jun 10. Epub 2021 Jun 10.

Department of Human Development and Family Studies.

The present study addressed calls for research to identify real-time predictors of prescription drug misuse (Schepis et al., 2020) by testing young adults' momentary reports of their negative mood and positive mood as predictors of event-level misuse in daily life. We implemented a 28-day ecological momentary assessment (EMA) procedure that collected individuals' mood and other contextual experiences in moments preceding prescription drug misuse. Read More

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Beyond olfaction: Beneficial effects of olfactory training extend to aging-related cognitive decline.

Behav Neurosci 2021 Jun 10. Epub 2021 Jun 10.

Smell and Taste Clinic.

Studies on olfactory training (OT) outcomes have mostly been limited to olfactory performance, while direct neural connections between olfactory system and amygdala-hippocampal complex allow expecting OT to have psychological effects. To address this hypothesis, we examined olfactory, cognitive and emotional effects of OT in the group of 68 subjects aged between 50 and 88 years ( = 62.8 ± 8. Read More

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Trapped by a first hypothesis: How rudeness leads to anchoring.

J Appl Psychol 2021 Jun 10. Epub 2021 Jun 10.

Department of Anesthesiology, Thomas Jefferson University Hospital.

In this article we explore the effect of encounters with rudeness on the tendency to engage in anchoring, one of the most robust and widespread cognitive biases. Integrating the self-immersion framework with the selective accessibility model (SAM), we propose that rudeness-induced negative arousal will narrow individuals' perspectives in a way that will make anchoring more likely. Additionally, we posit that perspective taking and information elaboration will attenuate the effect of rudeness on both negative arousal and subsequent anchoring. Read More

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Function-structure coupling: White matter functional magnetic resonance imaging hyper-activation associates with structural integrity reductions in schizophrenia.

Hum Brain Mapp 2021 Jun 10. Epub 2021 Jun 10.

The Clinical Hospital of Chengdu Brain Science Institute, MOE Key Lab for Neuroinformation, Center for Information in Medicine, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu, People's Republic of China.

White matter (WM) microstructure deficit may be an underlying factor in the brain dysconnectivity hypothesis of schizophrenia using diffusion tensor imaging (DTI). However, WM dysfunction is unclear in schizophrenia. This study aimed to investigate the association between structural deficits and functional disturbances in major WM tracts in schizophrenia. Read More

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Genetic changes and evolutionary analysis of canine circovirus.

Arch Virol 2021 Jun 8. Epub 2021 Jun 8.

College of Veterinary Medicine, Northeast Agricultural University, Harbin, 150030, China.

Canine circovirus (canineCV) has been found to be associated with vasculitis, hemorrhage, hemorrhagic enteritis, and diarrhea of canines. CanineCV, like other circoviruses, may also be associated with lymphoid depletion and immunosuppression. This circovirus has been detected worldwide in different countries and species. Read More

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Return-to-Play Times and Player Performance After ACL Reconstruction in Elite UEFA Professional Soccer Players: A Matched-Cohort Analysis From 1999 to 2019.

Orthop J Sports Med 2021 May 28;9(5):23259671211008892. Epub 2021 May 28.

Department of Orthopaedic Surgery, The Winnipeg Clinic, Winnipeg, Manitoba, Canada.

Background: Anterior cruciate ligament (ACL) rupture is one of the most common injuries afflicting soccer players and requires a lengthy recovery processes after reconstructive surgery. The impact of ACL reconstruction (ACLR) on return to play (RTP) time and player performance in professional soccer players remains poorly studied.

Purpose/hypothesis: To determine player performance and RTP rate and time after ACLR in elite professional soccer players with a retrospective matched-cohort analysis. Read More

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Biomechanical Properties of Double-Row Transosseous Rotator Cuff Repair Combined With the Cinch Stitch in the Lateral Row.

Orthop J Sports Med 2021 May 24;9(5):23259671211006040. Epub 2021 May 24.

Department of Orthopaedic Surgery, Saitama Medical University, Saitama, Japan.

Background: The self-cinching stitch has been verified to have high mechanical strength. The mechanical strength of combining transosseous rotator cuff repair (RCR) and the self-cinching stitch in the lateral row is unknown.

Purpose/hypothesis: The purpose of this study was to evaluate the biomechanical properties of transosseous RCR combined with the cinch stitch in the lateral row. Read More

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[Ordalie, sensation-seeking and impulsivity. Critical analysis of definitions].

Encephale 2021 Jun 4. Epub 2021 Jun 4.

Université de Bordeaux, 121, rue de la Béchade 33076 Bordeaux cedex, France; Equipe phénoménologie et déterminants des comportements appétitifs, Sanpsy CNRS USR 3413, 121, rue de la Béchade 33076 Bordeaux Cedex, France; Pôle interétablissement d'addictologie et filière régionale hospitalo-universitaire, CH Charles-Perrens et CHU de Bordeaux, 121, rue de la Béchade 33076 Bordeaux Cedex, France; Center for studies of addiction, department of psychiatry, Perelman school of medicine, university of Pennsylvania, Phildelphia, PA, États-Unis. Electronic address:

Background: In the fields of psychology and psychiatry, the use of the terms impulsivity, sensation-seeking and ordalie to refer to risk-taking behaviors can sometimes be confusing.

Objective: The objective of this study was to establish a clinical definition of the concepts of ordalie, sensation-seeking and impulsivity, in order to analyze the similarities and differences between these concepts.

Methods: We prioritized literature review articles with or without meta-analysis from the Medline database and supplemented with the Google-Scholar database. Read More

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