Genes Dis 2021 Sep 30;8(5):721-729. Epub 2020 Jun 30.
Department of Biological Sciences, SHUATS, Prayagraj, Uttar Pradesh, 211007, India.
In the era of antibiotic resistance, prediction of bacterial resistome profiles, likely to be associated with inactivation of new potential antibiotics is of utmost importance. Despite this, to the best of our knowledge, no tool exists for such prediction. Therefore, under the rationale that drugs with similar structures have similar resistome profiles, we developed two models, a deterministic model and a stochastic model, to predict the bacterial resistome likely to neutralize uncharacterized but potential chemical structures. Read More