Atherosclerosis 2021 Feb 26;324:38-45. Epub 2021 Feb 26.
the Second Clinical Medical College, Guangdong Medical University, Dongguan, 523808, China; Chronic Disease Management Center, Cha Shan Hospital, Guangdong Medical University, Dongguan 523382, China; Liaobu Hospital, Guangdong Medical University, Dongguan, Guangdong, 523400, China. Electronic address:
Background And Aims: Oxidized low-density lipoprotein (ox-LDL) is a key risk factor for atherosclerosis, but there are few reports on ox-LDL-mediated inflammation after injury. In this study, we investigated the effects of ox-LDL on endothelial injury and macrophage polarization and recruitment using human aortic endothelial cell line HAEC cells.
Methods: Changes in miRNA levels after ox-LDL treatment were assessed with qRT-PCR. Read More