Sci Rep 2021 Sep 10;11(1):18081. Epub 2021 Sep 10.
Department of Biology, Faculty of Science and Art, Giresun University, 28200, Giresun, Turkey.
In this study, the toxic effects of aflatoxin B (AFB) on Swiss albino mice and the protective effects of resveratrol were investigated. Physiological (body weight, liver and kidney weight), biochemical (aspartate aminotransferase-AST, alanine transaminase-ALT, blood urea nitrogen-BUN, creatinine, malondialdehyde-MDA and glutathione-GSH) and cytogenetic parameters (micronucleus-MN in buccal epithelium, erythrocyte and leukocyte cells and chromosomal aberrations-CAs) were used to determine the toxic effects. Additionally, scavenging effects of resveratrol against superoxide, hydrogen peroxide (HO) and 1,1-diphenyl-2-picrylhydrazyl (DPPH) radicals were also investigated. Read More