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A hypertension risk score for adults: a population-based cross-sectional study from Dubai Household Survey 2019.

Epidemiol Health 2021 Sep 8:e2021064. Epub 2021 Sep 8.

Department of Data Analysis, Research and Studies, Dubai Health Authority, Dubai, United Arab Emirates.

Objectives: To develop a risk score model for predicting hypertension specific to Dubai population in the United Arab Emirates (UAE) to facilitate prevention and early intervention.

Methods: A retrospective analysis of the Dubai Household Health Survey 2019 data was conducted. Demographic and physical parameters, as well as blood glucose levels, were included in the data. Read More

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September 2021

Utility of a Postural Stability/Perceptual Inhibition Dual Task for Identifying Concussion in Adolescents.

J Sport Rehabil 2021 Sep 15:1-6. Epub 2021 Sep 15.

Context: Research in the area of dual-task paradigms to assess sport-related concussion (SRC) status is growing, but additional assessment of this paradigm in adolescents is warranted.

Design: This case-control study compared 49 adolescent athletes aged 12-20 years with diagnosed SRC to 49 age- and sex-matched controls on visual-spatial discrimination and perceptual inhibition (PIT) reaction time tasks performed while balancing on floor/foam pad conditions.

Methods: The SRC group completed measures at a single time point between 1 and 10 days postinjury. Read More

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September 2021

Predicting length of stay and mortality among hospitalized patients with type 2 diabetes mellitus and hypertension.

Int J Med Inform 2021 Sep 4;154:104569. Epub 2021 Sep 4.

International Center for Health Information Technology, College of Medical Science and Technology, Taipei Medical University, Taipei, Taiwan; Graduate Institute of Biomedical Informatics, College of Medical Science and Technology, Taipei Medical University, Taipei, Taiwan. Electronic address:

Background: Type 2 diabetes mellitus (T2DM) and hypertension (HTN), both non-communicable diseases, are leading causes of death globally, with more imbalances in lower middle-income countries. Furthermore, poor treatment and management are known to lead to intensified healthcare utilization and increased medical care costs and impose a significant societal burden, in these countries, including Indonesia. Predicting future clinical outcomes can determine the line of treatment and value of healthcare costs, while ensuring effective patient care. Read More

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September 2021

A Comparison of Clinical Outcomes Between Two Different Models of Surgical Robots in Roux-en-Y Gastric Bypass.

J Laparoendosc Adv Surg Tech A 2021 Sep 17;31(9):969-977. Epub 2021 Aug 17.

General Surgery Department, Vall d'Hebron University Hospital, Universitat Autònoma de Barcelona, Barcelona, Spain.

For the past 20 years, robotic surgical systems have been used for the Roux-en-Y gastric bypass (RYGB). The da Vinci Surgical System (Intuitive Surgical, Inc.) has been one of the most used robotic platforms. Read More

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September 2021

Plasminogen activator inhibitor-1and Adiponectin are associated with metabolic syndrome components.

Am J Hypertens 2021 Sep 15. Epub 2021 Sep 15.

Departmento de Endocrinología, Escuela de Medicina, Pontificia Universidad Católica de Chile. Avda Libertador Bernardo O´Higgins, Santiago Centro, Santiago, Chile.

Background: We aimed to study the associations of adipocytokines, endothelial damage markers, and hs-CRP with metabolic syndrome (MetS) components.

Methods: This cross-sectional study included 202 subjects categorized into MetS and No-MetS according to Harmonizing ATP III.

Results: Subjects with MetS showed higher levels of pro-inflammatory molecules but significantly lower adiponectin levels than subjects with No-MetS. Read More

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September 2021

Shear thickening behavior in dense repulsive and attractive suspensions of hard spheres.

Soft Matter 2021 Sep 15;17(35):8047-8058. Epub 2021 Sep 15.

Micro/Bio/Nanofluidics Unit, Okinawa Institute of Science and Technology Graduate University, Okinawa, 904-0495, Japan.

Shear thickening in stable dense colloidal suspensions is a reversible phenomenon and no hysteresis is observed in the flow curve measurements. However, a reduction in the stability of colloids promotes particle aggregation and introduces a time dependent rheological response. In this work, by using a model colloidal system of hard spherical silica particles (average diameter of 415 nm) with varying particle volume fractions 0. Read More

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September 2021

Unidirectional water transport on a two-dimensional hydrophilic channel with anisotropic superhydrophobic barriers.

Soft Matter 2021 Sep 15;17(35):8153-8159. Epub 2021 Sep 15.

Beijing Key Laboratory of Cryo-Biomedical Engineering, CAS Key Laboratory of Cryogenics, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing 100190, P. R. China.

Many creatures have a unique anisotropic structure and special wettability on their skins, presenting intriguing water transporting properties. Inspired by the biosphere, a two-dimensional titanium dioxide-based hydrophilic channel possessing anisotropic superhydrophobic barriers was synthesized. This channel demonstrates unidirectional water transporting properties. Read More

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September 2021

Load-dependent energy dissipation induced by the tip-membrane friction on suspended 2D materials.

Phys Chem Chem Phys 2021 Sep 15;23(35):19819-19826. Epub 2021 Sep 15.

State Key Laboratory, Tsinghua University, Beijing, China.

The tip-membrane interface plays a critical role in characterizing the mechanical properties of ultrathin 2D materials by commonly employed nanoindentation based on atomic force microscopy (AFM). However, the reliability of the assumption that the tip-membrane interface remains pinned during nanoindentation remains unclear, which may introduce unignorable uncertainty in evaluating their true mechanical properties. In this work, it is reported that load-dependent frictional behavior would occur on the tip-membrane interface during nanoindentation tests on monolayer and multilayer suspended WS and graphene, and the curve hysteresis could be well explained by the stick-slip behavior. Read More

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September 2021

Comparison of machine learning methods for estimating case fatality ratios: An Ebola outbreak simulation study.

PLoS One 2021 15;16(9):e0257005. Epub 2021 Sep 15.

Department of Infectious Disease Epidemiology, MRC Centre for Global Infectious Disease Analysis, Imperial College London, London, United Kingdom.

Background: Machine learning (ML) algorithms are now increasingly used in infectious disease epidemiology. Epidemiologists should understand how ML algorithms behave within the context of outbreak data where missingness of data is almost ubiquitous.

Methods: Using simulated data, we use a ML algorithmic framework to evaluate data imputation performance and the resulting case fatality ratio (CFR) estimates, focusing on the scale and type of data missingness (i. Read More

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September 2021

Plasma glycated CD59 predicts postpartum glucose intolerance after gestational diabetes.

Eur J Endocrinol 2021 Sep 1. Epub 2021 Sep 1.

J Halperin, Divisions of Hematology, Bringham and Women's Hospital, Harvard Medical School, Boston, United States.

Aims: To assess whether in women with gestational diabetes mellitus (GDM), postpartum plasma glycated CD59 (pGCD59) levels predict conversion to glucose intolerance diagnosed with an oral glucose tolerance test (OGTT).

Methods: Blood levels of pGCD59 were measured in a case-control study of 105 women with GDM who underwent a 75g OGTT three months postpartum. The 35 postpartum glucose intolerant cases were individually matched for age, BMI, ethnic origin and parity with 70 women with GDM but normal postpartum OGTT (controls). Read More

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September 2021

Can waist circumference be a predictor of bone mineral density independently of BMI in middle-aged adults?

Endocr Connect 2021 Sep 1. Epub 2021 Sep 1.

Z Zhu, Department of Osteoporosis Care, Control Xiaoshan Affiliated Hospital of Wenzhou Medical University, Hangzhou, 311200, China.

Background: Obesity and osteoporosis are major public health issues globally. The prevalence of these two diseases prompts the need to better understand the relationship between them. Previous studies, however, have yielded controversial findings on this issue. Read More

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September 2021

Parameter-Free Loss for Class-Imbalanced Deep Learning in Image Classification.

IEEE Trans Neural Netw Learn Syst 2021 Sep 15;PP. Epub 2021 Sep 15.

Current state-of-the-art class-imbalanced loss functions for deep models require exhaustive tuning on hyperparameters for high model performance, resulting in low training efficiency and impracticality for nonexpert users. To tackle this issue, a parameter-free loss (PF-loss) function is proposed, which works for both binary and multiclass-imbalanced deep learning for image classification tasks. PF-loss provides three advantages: 1) training time is significantly reduced due to NO tuning on hyperparameter(s); 2) it dynamically pays more attention on minority classes (rather than outliers compared to the existing loss functions) with NO hyperparameters in the loss function; and 3) higher accuracy can be achieved since it adapts to the changes of data distribution in each mini-batch instead of the fixed hyperparameters in the existing methods during training, especially when the data are highly skewed. Read More

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September 2021

Assessment of Red Cell Distribution Width, Platelet/lymphocyte Ratio, Systemic Immune-inflammation Index, and Neutrophil/lymphocyte Ratio Values in Patients with Central Retinal Artery Occlusion.

Ocul Immunol Inflamm 2021 Sep 15:1-5. Epub 2021 Sep 15.

Department of Ophthalmology, Sakarya Training and Research Hospital, Sakarya, Turkey.

Purpose: To evaluate complete blood count (CBC)-derived inflammatory indices in central retinal artery occlusion (CRAO).

Methods: A total of 42 patients with CRAO (CRAO group) and 42 age- and sex-matched subjects without CRAO (Control group) were included. CBC parameters including red cell distribution width (RDW) levels were assayed. Read More

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September 2021

Durability of Dolutegravir-Based Regimens: A 5-Year Prospective Observational Study.

AIDS Patient Care STDS 2021 Sep;35(9):342-353

Unit of Infectious and Tropical Diseases, Department of Medical, Surgical and Experimental Sciences, University of Sassari, Sassari, Italy.

This study evaluates the frequency and causes of dolutegravir (DTG) discontinuation along 5 years of follow-up, in both antiretroviral treatment (ART)-naive and experienced people living with HIV (PLWH). This is a prospective multi-center cohort study enrolling PLWH on DTG from July 2014 until November 2020. DTG-durability was investigated using the Kaplan-Meier survival curve. Read More

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September 2021

Prediction accuracy of commonly used pneumonia severity scores in Aboriginal patients with severe community-acquired pneumonia - a retrospective study.

Intern Med J 2021 Sep 15. Epub 2021 Sep 15.

Department of Medicine, Alice Springs Hospital, Central Australian Health Service, Alice Springs, Northern Territory,, Australia.

Aims: Assess the prediction accuracy of pneumonia severity scores in Aboriginal patients with severe community-acquired pneumonia (SCAP) and identify risk factors for poor prognosis.

Methods: Retrospective cohort study examining Aboriginal patients admitted to intensive care unit (ICU) with confirmed SCAP between January 2011 and December 2014. Severity scores were calculated for SMARTCOP, SMARTACOP, CURB65, PSI, IDSA/ATS SCAP (IASCAP) and APACHE II/III scores using medical records. Read More

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September 2021

Intracranial Pressure and Cerebral Hemodynamic Monitoring After Cardiac Arrest in Pediatric Pigs Using Contrast Ultrasound-Derived Parameters.

J Ultrasound Med 2021 Sep 15. Epub 2021 Sep 15.

Department of Radiology, Children's Hospital of Philadelphia, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.

Objectives: We explore the correlation of contrast-enhanced ultrasound (CEUS) parameters to intracranial pressure (ICP) in a porcine experimental model of pediatric cardiac arrest.

Methods: Eleven pediatric pigs underwent electrically induced cardiac arrest followed by cardiopulmonary resuscitation. ICP was measured using intracranial bolt monitor and CEUS was monitored through a cranial window. Read More

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September 2021

Polycystic ovary syndrome: clinical and laboratory variables related to new phenotypes using machine-learning models.

J Endocrinol Invest 2021 Sep 15. Epub 2021 Sep 15.

Departamento de Genética, Ecologia e Evolução, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil.

Purpose: Polycystic Ovary Syndrome (PCOS) is the most frequent endocrinopathy in women of reproductive age. Machine learning (ML) is the area of artificial intelligence with a focus on predictive computing algorithms. We aimed to define the most relevant clinical and laboratory variables related to PCOS diagnosis, and to stratify patients into different phenotypic groups (clusters) using ML algorithms. Read More

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September 2021

Amide proton transfer imaging in differentiation of type II and type I endometrial carcinoma: a pilot study.

Jpn J Radiol 2021 Sep 15. Epub 2021 Sep 15.

Division of Radiology, Department of Multidisciplinary Internal Medicine, Faculty of Medicine, Tottori University, 36-1, Nishi-cho, Yonago, Tottori, 683-8504, Japan.

Purpose: This study aimed at evaluating the efficacy of amide proton transfer (APT) imaging in differentiation of type II and type I uterine endometrial carcinoma.

Materials And Methods: Thirty-three patients diagnosed with uterine endometrial carcinoma, including 24 with type I and 9 with type II carcinomas, underwent APT imaging. Two readers evaluated the magnetization transfer ratio at 3. Read More

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September 2021

Medial closure supracondylar femoral osteotomy: an effective solution for long-term treatment of arthritic valgus knee?

J Orthop Traumatol 2021 Sep 15;22(1):35. Epub 2021 Sep 15.

ASST Centro Specialistico Ortopedico Traumatologico Gaetano Pini-CTO, Università Degli Studi Di Milano, P.zza A. Ferrari 1, 20122, Milan, Italy.

Purpose: The aim of this work was to retrospectively analyze the clinical, subjective, and radiological results of medial closing-wedge distal femur osteotomy (MCW-DFO) for the treatment of osteoarthritis (OA) in valgus knee at medium- to long-term follow-up.

Materials And Methods: A total of 57 patients (62 knees) treated with MCW-DFO between 1984 and 2018 were included in the study. Patient age at the time of the surgery ranged between 28 and 61 years (average: 48 years). Read More

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September 2021

Mutation of the sixth amino acid of the Rep protein has no effect on porcine circovirus 2b but enhances porcine circovirus 2d replication in vitro.

Arch Virol 2021 Sep 15. Epub 2021 Sep 15.

Key Laboratory of Animal Resistance Research, College of Life Science, Shandong Normal University, 88 East Wenhua Rd., Jinan, 250014, People's Republic of China.

Porcine circovirus type 2 (PCV2) is the etiological agent of post-weaning multisystemic wasting syndrome (PMWS). The original prevalent genotype, PCV2a, has been replaced by genotypes 2b and 2d in the swine population worldwide. The Rep protein is critical for viral replication. Read More

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September 2021

Clinical importance of preoperative red-cell volume distribution width as a prognostic marker in patients undergoing radical surgery for pancreatic cancer.

Surg Today 2021 Sep 15. Epub 2021 Sep 15.

Department of Pancreatic-Biliary Surgery, Affiliated Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1095 Jiefang Ave, Wuhan, 430030, China.

Background And Purpose: A new noninvasive biomarker is being sought to predict the prognosis of patients with pancreatic cancer. Red-cell volume distribution width (RDW), a descriptive parameter for erythrocyte variation, has been shown to have prognostic value for some tumor types. Our purpose was to assess the RDW value to predict the prognosis of patients with pancreatic cancer. Read More

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September 2021

T1 relaxation times and MR elastography-derived stiffness: new potential imaging biomarkers for the assessment of chronic pancreatitis.

Abdom Radiol (NY) 2021 Sep 15. Epub 2021 Sep 15.

Mech-Sense, Department of Radiology, Aalborg University Hospital, Hobrovej 18-22, PO. Box 365, 9000, Aalborg, Denmark.

Purpose: Non-invasive imaging methods to detect morphological changes of the pancreas in patients with mild chronic pancreatitis (CP) are needed. This study aimed to compare magnetic resonance imaging-based parameters, pancreatic volume, T1 mapping, magnetic resonance elastography (MRE), and proton density fat fraction between CP patients and controls, and determine the diagnostic performance for diagnosing different stages of CP.

Methods: Nineteen patients with mild CP (Cambridge grade 2 or less or recurring acute pancreatitis; n = 19), 30 with moderate/severe CP (Cambridge grade 3 and 4), and 35 healthy controls underwent pancreatic magnetic resonance imaging to assess the above mentioned magnetic resonance imaging-based parameters. Read More

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September 2021

Conduction delays after transcatheter aortic valve implantation with balloon-expandable prosthesis and high implantation technique.

Heart Vessels 2021 Sep 15. Epub 2021 Sep 15.

Division of Cardiology, Cardiovascular Department, "San Carlo" Regional Hospital, Potenza, Italy.

Performing transcatheter aortic valve implantation with high implantation technique, i.e. with an aorto-ventricular ratio > 60/40, reduces the need of permanent pacemaker implantation. Read More

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September 2021

Deep-Learning-Based Pre-Diagnosis Assessment Module for Retinal Photographs: A Multicenter Study.

Transl Vis Sci Technol 2021 Sep;10(11):16

Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong.

Purpose: Artificial intelligence (AI) deep learning (DL) has been shown to have significant potential for eye disease detection and screening on retinal photographs in different clinical settings, particular in primary care. However, an automated pre-diagnosis image assessment is essential to streamline the application of the developed AI-DL algorithms. In this study, we developed and validated a DL-based pre-diagnosis assessment module for retinal photographs, targeting image quality (gradable vs. Read More

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September 2021

The Algorithm Examining the Risk of Massive Transfusion (ALERT) Score Accurately Predicts Massive Transfusion at the Scene of Injury and on Arrival to the Trauma Bay: A Retrospective Analysis.

Shock 2021 Oct;56(4):529-536

Division of Critical Care, Department of Anesthesiology, R. Adams Cowley Shock Trauma Center, Baltimore, Maryland.

Background: Massive transfusion (MT) is required to resuscitate traumatically injured patients with complex derangements. Scoring systems for MT typically require laboratory values and radiological imaging that may delay the prediction of MT.

Study Design: The Trauma ALgorithm Examining the Risk of massive Transfusion (Trauma ALERT) study was an observational cohort study. Read More

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October 2021

A Tool to Distinguish Viral From Bacterial Pneumonia.

Pediatr Infect Dis J 2021 Sep 14. Epub 2021 Sep 14.

From the Pediatrics Research Group, Pediatrics Department, Hospital Universitario Infanta Sofía, Universidad Europea de Madrid, Madrid, Spain Pediatric Research and Clinical Trials Unit (UPIC), Instituto de Investigación Sanitaria Hospital 12 de Octubre (IMAS12), Madrid, Spain Fundación para la Investigación, Biomédica del Hospital 12 de Octubre, Madrid, Spain RITIP (Traslational Research Network in Pediatric Infectious Diseases) Pediatric Infectious Diseases Unit, Department of Pediatrics, Hospital Universitario 12 de Octubre Microbiology Department, Hospital Universitario Ramón y Cajal, Instituto Ramón y Cajal para la Investigación Sanitaria, Madrid, Spain *Microbiology Department, Laboratorio BR Salud, Hospital Universitario Infanta Sofía, San Sebastián de los Reyes, Madrid, Spain †Pediatrics Department, Hospital Infanta Cristina, Madrid, Spain ‡Pediatrics Deparment, Hospital Universitario Puerta de Hierro, Madrid, Spain §Pediatrics Department, Hospital Universitario Ramón y Cajal; and ¶Universidad de Alcalá de Henares, Madrid, Spain.

Background: Establishing the etiology of community-acquired pneumonia (CAP) in children at admission is challenging. Most of the admitted children with CAP receive antibiotics. We aimed to build and validate a diagnostic tool combining clinical, analytical and radiographic features to differentiate viral from bacterial CAP, and among bacterial CAP, typical from atypical bacteria. Read More

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September 2021

A Triphasic Split-bolus Contrast Injection Protocol for Artery-vein Separation During Pulmonary Computed Tomographic Angiography.

J Thorac Imaging 2021 Sep 15. Epub 2021 Sep 15.

Department of Radiological Science, Faculty of Health Sciences, Junshin Gakuen University Department of Health Sciences, Graduate School of Medical Sciences, Kyushu University, Fukuoka Department of Radiological Technology, Yamaguchi University Hospital Department of Radiology, National Hospital Organization Kanmon Medical Center, Yamaguchi Division of Health Sciences, Graduate School of Medical Sciences, Kanazawa University, Kanazawa, Japan.

Purpose: Accurate artery-vein separation on pulmonary computed tomographic (CT) angiography is desirable for preoperative 3-dimensional image simulation, while using a minimal amount of contrast medium. This study aimed to verify whether a split-bolus contrast enhancement protocol with test-bolus tracking would provide contrast differentiation between the pulmonary arteries (PA) and pulmonary veins (PV) during high-pitch single-pass CT angiography.

Materials And Methods: Fifty patients underwent pulmonary CT angiography with a triphasic split-bolus injection protocol with the main bolus of contrast medium for 6 seconds, followed by a subsequent bolus of 20% diluted contrast medium/80% saline for another 6 seconds and a 5-second saline chaser. Read More

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September 2021

Shift in Social Media App Usage During COVID-19 Lockdown and Clinical Anxiety Symptoms: Machine Learning-Based Ecological Momentary Assessment Study.

JMIR Ment Health 2021 Sep 15;8(9):e30833. Epub 2021 Sep 15.

Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, United States.

Background: Anxiety symptoms during public health crises are associated with adverse psychiatric outcomes and impaired health decision-making. The interaction between real-time social media use patterns and clinical anxiety during infectious disease outbreaks is underexplored.

Objective: We aimed to evaluate the usage pattern of 2 types of social media apps (communication and social networking) among patients in outpatient psychiatric treatment during the COVID-19 surge and lockdown in Madrid, Spain and their short-term anxiety symptoms (7-item General Anxiety Disorder scale) at clinical follow-up. Read More

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September 2021

Prehospital Evaluation of the FAST-ED as a Secondary Stroke Screen to Identify Large Vessel Occlusion Strokes.

Prehosp Emerg Care 2021 Sep 15:1-8. Epub 2021 Sep 15.

Mecklenburg EMS Agency, Charlotte, North Carolina, USA.

Introduction: The Field Assessment Stroke Triage for Emergency Destination (FAST-ED) was developed to identify Large Vessel Occlusion Strokes (LVOS) presenting out of hospital, although there is limited prospective research validating its use in this setting. This study evaluated the test characteristics of the FAST-ED to identify LVOS when used as a secondary stroke screen in the prehospital environment. Secondary analysis compared the performance of the CPSS and the FAST-ED in identifying an LVOS. Read More

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September 2021

Quantitative physical examination indicators to detect patients with stenosis at a high risk of thrombosis at hemodialysis vascular access sites: A retrospective case-control study.

J Vasc Access 2021 Sep 15:11297298211045505. Epub 2021 Sep 15.

Department of Nephrology, Yuan's General Hospital, Kaohsiung.

Background: Quantitative physical examination (PE) indicators, including palpable pulsatility length and outflow scores, can be used to quantify stenosis severity at hemodialysis vascular access sites. It is known that the risk of high-shear-related thrombosis is increased when the minimal luminal diameter (MLD) of stenosis decreases. At present, MLD is measured using sonography or angiography. Read More

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September 2021