1,076,770 results match your criteria crude extract


Effective separation of water-DMSO through solvent resistant membrane distillation (SR-MD).

Water Res 2021 Apr 1;197:117103. Epub 2021 Apr 1.

Singapore Membrane Technology Centre, Nanyang Environment and Water Research Institute, Nanyang Technological University, Singapore 637141, Singapore; School of Civil and Environmental Engineering, Nanyang Technological University, Singapore 639798, Singapore. Electronic address:

The treatment of organic waste or wastewater with high organic solvent content has been challenging in industries as it cannot be done effectively using conventional wastewater treatment technologies such as biodegradation and advanced oxidation process. Solvent resistant membrane distillation (SR-MD) was proposed as an energy-efficient alternative to treat these waste streams but its application is hampered by the lack of solvent-resistant membranes, and there is a research gap in studying the feeds with water-solvent mixtures. In this work, ceramic tubular membranes with different pore sizes and structures were molecularly grafted with 1H,1H,2H,2H-perfluorodecyltriethoxysilane to obtain hydrophobic ceramic membranes for SR-MD. Read More

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Separation and purification of magnoflorine, spinosin and 6'''-feruloyspinosin from Ziziphi Spinosae Semen by high-speed counter-current chromatography.

J Sep Sci 2021 Apr 13. Epub 2021 Apr 13.

Tianjin Key Laboratory on Technologies Enabling Development of Clinical Therapeutics and Diagnostics, School of Pharmacy, Tianjin Medical University, Tianjin, 300070, China.

In the study, high-speed counter-current chromatography was used for separation and purification of magnoflorine, spinosin and 6'''-feruloyspinosin from Ziziphi Spinosae Semen. With n-butanol-ethyl acetate-water (2:3:5, v/v) as the optimum solvent system, about 75 mg of magnoflorine, 110 mg of spinosin and 40 mg of 6'''-feruloyspinosin were isolated from 0.5 g of crude extract of Ziziphi Spinosae Semen, with the purity of 95. Read More

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Experimental and Ab Initio Characterization of Mononuclear Molybdenum Dithiocarbamates in Lubricant Mixtures.

Langmuir 2021 Apr 13. Epub 2021 Apr 13.

Department of Physics and Astronomy, University of Bologna, 40127 Bologna, Italy.

Molybdenum dithiocarbamates (MoDTCs) are a class of lubricant additives widely employed in automotives. Most of the studies concerning MoDTC take into account the dimeric structures because of their industrial relevance, with the mononuclear compounds usually neglected, because isolating and characterizing subgroups of MoDTC molecules are generally difficult. However, the byproducts of the synthesis of MoDTC can impact the friction reduction performance at metallic interfaces, and the effect of mononuclear MoDTC (mMoDTC) compounds in the lubrication has not been considered yet in the literature. Read More

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Cytochrome P450 Enzyme Inhibition and Herb-Drug Interaction Potential of Medicinal Plant Extracts Used for Management of Diabetes in Nigeria.

Eur J Drug Metab Pharmacokinet 2021 Apr 12. Epub 2021 Apr 12.

Department of Biomedical and Pharmaceutical Sciences, College of Pharmacy, University of Rhode Island, 7 Greenhouse Rd, Kingston, RI, 02881, USA.

Background And Objective: The use of herbal medicines is common in Africa, and patients often use a combination of herbs and drugs. Concurrent herbal and pharmaceuticals treatments can cause adverse effects through herb-drug interactions (HDI). This study evaluated the potential risk of HDI for five medicinal plants, Vernonia amygdalina, Ocimum gratissimum, Moringa oleifera, Azadirachta indica, and Picralima nitida, using in vitro assays. Read More

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Interferon-γ Response of subsp. Infected Goats to Recombinant and Synthetic Mycobacterial Antigens.

Front Vet Sci 2021 26;8:645251. Epub 2021 Mar 26.

Animal and Plant Health Agency, Addlestone, United Kingdom.

Despite its potential for early diagnosis of subsp. (MAP) infection, the IFN-γ release assay is not used routinely, because of low specificity of the established crude antigen preparation Johnin (PPDj). Limited data are available assessing the potential of MAP-derived protein and lipopeptide antigens to replace PPDj in assays for goats, while cattle and sheep have been studied more extensively. Read More

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Efficient utilization of date palm waste for the bioethanol production through strain.

Food Sci Nutr 2021 Apr 21;9(4):2066-2074. Epub 2021 Feb 21.

National Institute of Food Science and Technology University of Agriculture Faisalabad Faisalabad Pakistan.

Dates ( L.) are rich in nutritional compounds, particularly in sugars. Sugars offer anaerobic fermentation, used for bioethanol production. Read More

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Isolation and Identification of Antibacterial Bioactive Compounds From L2.

Front Microbiol 2021 24;12:645484. Epub 2021 Mar 24.

Key Laboratory of Plant Resource Conservation and Germplasm Innovation in Mountainous Region (Ministry of Education), Collaborative Innovation Center for Mountain Ecology & Agro-Bioengineering, College of Life Sciences/Institute of Agro-bioengineering, Guizhou University, Guiyang, China.

Bacterial metabolites exhibit a variety of biologically active compounds including antibacterial and antifungal activities. It is well known that is considered to be a promising source of bioactive secondary metabolites. Most plant pathogens have an incredible ability to mutate and acquire resistance, causing major economic losses in the agricultural field. Read More

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Endocrine Disruptor Impacts on Fish From Chile: The Influence of Wastewaters.

Front Endocrinol (Lausanne) 2021 25;12:611281. Epub 2021 Mar 25.

Biological Sciences, University of Calgary, Calgary, AB, Canada.

Industrial wastewaters and urban discharges contain complex mixtures of chemicals capable of impacting reproductive performance in freshwater fish, called endocrine-disrupting compounds (EDCs). In Chile, the issue was highlighted by our group beginning over 15 years ago, by analyzing the impacts of pulp and paper mill effluents (PPME) in the Biobio, Itata, and Cruces River basins. All of the rivers studied are important freshwater ecosystems located in the Mediterranean region of Central Chile, each with a unique fish biodiversity. Read More

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Development of an effective method based upon second-order overlapping repeated sample injections for isolation of carotenoids from Lycium barbarum L. fruits with elution-extrusion counter-current chromatography.

J Chromatogr A 2021 Mar 27;1645:462026. Epub 2021 Mar 27.

CAS Key Laboratory of Chemistry of Northwestern Plant Resources and Key Laboratory of Natural Medicine of Gansu Province, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences (CAS), Lanzhou, P. R. China; University of Chinese Academy of Sciences, Beijing, P. R. China. Electronic address:

Carotenoids are one of the main active components in Lycium barbarum L. fruit, which has a wide range of excellent biological activities. In this study, a novel second-order overlapping repeated injection method with elution-extrusion counter-current chromatography was developed for isolation and preparation of carotenoids from L. Read More

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Monitoring land use and soil salinity changes in coastal landscape: a case study from Senegal.

Environ Monit Assess 2021 Apr 10;193(5):259. Epub 2021 Apr 10.

Department of Agricultural Engineering, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.

Soil salinity is a major issue causing land degradation in coastal areas. In this study, we assessed the land use and soil salinity changes in Djilor district (Senegal) using remote sensing and field data. We performed land use land cover changes for the years 1984, 1994, 2007, and 2017. Read More

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A general chemical crosslinking strategy for structural analyses of weakly interacting proteins applied to preTCR-pMHC complexes.

J Biol Chem 2021 Jan 8;296:100255. Epub 2021 Jan 8.

Laboratory of Immunobiology, Dana Farber Cancer Institute, Boston, Massachusetts, USA; Department of Medical Oncology, Dana Farber Cancer Institute, Boston, Massachusetts, USA; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts, USA; Department of Dermatology, Harvard Medical School, Boston, Massachusetts, USA. Electronic address:

T lymphocytes discriminate between healthy and infected or cancerous cells via T-cell receptor-mediated recognition of peptides bound and presented by cell-surface-expressed major histocompatibility complex molecules (MHCs). Pre-T-cell receptors (preTCRs) on thymocytes foster development of αβT lymphocytes through their β chain interaction with MHC displaying self-peptides on thymic epithelia. The specific binding of a preTCR with a peptide-MHC complex (pMHC) has been identified previously as forming a weak affinity complex with a distinct interface from that of mature αβTCR. Read More

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January 2021

Detrimental effects of 6 months exposure to very low doses of a mixture of six pesticides associated with chronic vitamin deficiency on rats.

Food Chem Toxicol 2021 Apr 6:112188. Epub 2021 Apr 6.

Department of Toxicology, University of Medicine and Pharmacy, Faculty of Pharmacy, Craiova, 200349, Romania. Electronic address:

This study aimed to evaluate the long-term low-dose effects of exposure to a mixture of 6 pesticide active substances (diquat, imazamox, imazethapyr, tepraloxydin, bentazone, acifluorfen) and to elucidate if chronic vitamin deficiency can influence their toxicity. Two hundred Wistar rats were divided in 4 groups: a vitamin-sufficiency control group, a vitamin-deficiency control group, a vitamin sufficiency test group and a vitamin-deficiency test group. The test groups were treated with the aforementioned pesticides at doses 100 times lower than the corresponding NOAEL. Read More

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Complex coacervate formation between hemp protein isolate and gum Arabic: Formulation and characterization.

Int J Biol Macromol 2021 Apr 6;182:144-153. Epub 2021 Apr 6.

Laboratory of Food Chemistry and Technology, School of Chemistry, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece. Electronic address:

In this study, intermolecular interactions and structure formation between hemp protein isolate (HPI) and gum Arabic (GA) were investigated to unravel their complexation mechanisms. For this purpose, structural transition as a function of pH (2.0-7. Read More

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Comprehensive Screening of Polycyclic Aromatic Hydrocarbons and Similar Compounds Using GC-APLI-TIMS-TOFMS/GC-EI-MS.

Anal Chem 2021 Apr 9. Epub 2021 Apr 9.

Department of Chemistry and Biochemistry, Florida International University, Miami, Florida 33199, United States.

In the present work, a novel workflow based on complementary gas-phase separations for the identification of isomeric PAHs from complex mixtures is described. This is the first report on the coupling of gas chromatography (GC), atmospheric pressure laser ionization (APLI), and trapped ion mobility spectrometry-mass spectrometry (TIMS-MS) for the characterization of polycyclic aromatic hydrocarbons. Over a hundred known unknowns are uniquely identified based on the molecular ion retention indices (5%), mobility (RSD < 0. Read More

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Bioavailability of copper and nickel in naturally metal-enriched soils of Carajás Mining Province, Eastern Amazon, Brazil.

Environ Monit Assess 2021 Apr 9;193(5):256. Epub 2021 Apr 9.

Soil Science Department, Federal University of Lavras, Lavras, Minas Gerais, 3037, 37200-900, Brazil.

Naturally elevated contents of copper (Cu) and nickel (Ni) are found in soils worldwide, and their potential toxicity is better understood when geochemical reactive fractions are identified and monitored. Thus, this study aimed to assess the bioavailability of Cu and Ni and estimate environmental risks in naturally metal-enriched soils of Carajás Mining Province, Eastern Amazon, Brazil. For that, 58 surficial soil samples were analyzed for their extractable contents of Cu and Ni by Mehlich 1. Read More

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Characteristics and potential sources of wintertime air pollution in Linfen, China.

Environ Monit Assess 2021 Apr 8;193(5):252. Epub 2021 Apr 8.

Beijing Polytechnic, Beijing, 100176, China.

Linfen in China's Shanxi Province suffers severe air pollution in winter. Understanding the characteristics of air pollution and providing scientific support to mitigate such pollution are urgent matters. This study investigated the variations of PM, PM, NO, SO, O, and CO in Linfen between December 1, 2019 and February 29, 2020. Read More

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Evaluation of field calibration methods and performance of AQMesh, a low-cost air quality monitor.

Environ Monit Assess 2021 Apr 8;193(5):251. Epub 2021 Apr 8.

Department of Building Engineering, Energy Systems and Sustainability Science, Faculty of Engineering and Sustainable Development, University of Gävle, Gavle, Sweden.

Field calibrations of NO, NO, and PM from AQMesh Air Quality Monitors (AQMs) were conducted during a summer and an autumn period in a busy street in a midsize Swedish city. All the three linear calibration procedures studied (postscaled, bisquare, and orthogonal data) significantly reduced the ranges and magnitudes of the performance indicators to yield more reliable results than the raw data. The improvements were sufficient to satisfy the European Union (EU) Data Quality Objective (DQO) for indicative measurements as compared to reference data only for NO (above 50 µg m) and NO (above 30 µg m) during the autumn calibration period. Read More

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Order-disorder in room-temperature ionic liquids probed via methyl quantum tunneling.

Struct Dyn 2021 Mar 5;8(2):024303. Epub 2021 Apr 5.

Neutron Scattering Division, Oak Ridge National Laboratory, Oak Ridge, Tennessee 37831, USA.

Room-temperature ionic liquids are promising candidates for applications ranging from electrolytes for energy storage devices to lubricants for food and cellulose processing to compounds for pharmaceutics, biotransformation, and biopreservation. Due to the ion complexity, many room-temperature ionic liquids readily form amorphous phases upon cooling, even at modest rates. Here, we investigate two commonly studied imidazolium-based room-temperature ionic liquids, 1-ethyl-3-methylimidazolium tetrafluoroborate and 1-ethyl-3-methylimidazolium bis(trifluoromethylsulfonyl)imide, as well as their mixtures, to demonstrate how the complex interplay between the crystalline and amorphous phases is affected by the processing conditions, such as thermal history, liquid mixing, and applied pressure. Read More

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Evaluation of effect of Acacia jacquemontii Benth. on blood pressure in normotensive and fructose induced hypertensive sprague dawley rats: An ethnopharmacological approach.

Pak J Pharm Sci 2020 Sep;33(5(Supplementary)):2341-2345

College of Pharmacy, Jouf University, Aljouf, Sakaka, 2014, Saudi Arabia.

Acacia jacquemontii Benth. is used traditionally to treat hypertension but no scientific literature supports this claim. So, this study was aimed at validating this claim. Read More

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September 2020

Insight on the fractionations and structural characterizations of innovative antidiarrheal compounds screened from leaves of Psidium guajava of local origin in Pakistan.

Pak J Pharm Sci 2020 Sep;33(5(Supplementary)):2323-2329

Imran Adrees College of Pharmacy, 3Km Daska Road, Sialkot, Pakistan.

Numerous ailments have been effectively treated with natural plants for long time all over the world. Plants provided a back bone for the exploration of novel medicinal compounds. Therefore, chief focus of our study was to isolate the biologically active compounds from the plant source and evaluate their antidiarrheal potentials, as diarrhea is still the most dominant disease in developing countries. Read More

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September 2020

Pharmacological investigation of activities pertaining to modulation of gastrointestinal, respiratory and cardiovascular parameters by Indigofera argentea in experimental models.

Pak J Pharm Sci 2020 Sep;33(5(Supplementary)):2257-2267

Department of Pharmacology, Faculty of Pharmacy, Bahauddin Zakariya University, Multan, Pakistan.

Indigofera argentea is widely used for the management of gastrointestinal, respiratory and cardiac disorders. This study was done to explore scientific basis of its uses. Aqueous methanolic extract of Indigofera argentea and its fractions were studied on isolated tissues of rabbit's jejunum, trachea, aorta and atrium. Read More

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September 2020

Blood pressure lowering effects of Ranunculus scleratus Linn. in normal and fructose induced hypertensive rats and estimation of underlying mechanisms.

Pak J Pharm Sci 2020 Sep;33(5(Supplementary)):2243-2247

Faculty of Pharmacy, The University of Lahore, Lahore.

Ranunculus scleratus Linn. is used in folk medicine to treat hypertension. This study was aimed at providing validation to its traditional use and to explore underlying mechanisms of action. Read More

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September 2020

Phytochemical, antimicrobial and time-kill kinetics potentials of Euphorbia nivulia Buch.-Ham.: A Cholistan desert medicinal plant.

Pak J Pharm Sci 2020 Sep;33(5(Special)):2461-2469

Department of Pharmacognosy, Faculty of Pharmacy, Gomal University, Dera Ismail Khan, Pakistan.

Euphorbia nivulia a locally occurring plant species possesses antiseptic, analgesic and anti-inflammatory properties and is ethnopharmacologically used in various ailments like skin, ear disorders, boils, and worm infestation. Preliminary phytochemical screening showed presence of flavonoids, polyphenolics, glycosides, alkaloids, tannins and triterpenoids in (70% aqueous-ethanolic) Euphorbia nivulia crude extract (En cr) and its four fractions, i.e. Read More

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September 2020

[In the United Kingdom, volunteer caregivers to reinforce COVID vaccination teams].

Rev Infirm 2021 Apr 22;70(270):33-34. Epub 2021 Feb 22.

c/o La revue de l'infirmière, 65, rue Camille-Desmoulins, 92442 Issy-les-Moulineaux cedex, France.

The United Kingdom, like many countries, is strongly impacted by the COVID-19 pandemic. The vaccination campaign was launched last December. Ghislaine Young, a nurse, and Jim Hodgson, a general practitioner, both retired, are offering their services as vaccinators to help fight this epidemic. Read More

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The use of medicinal plants to prevent COVID-19 in Nepal.

J Ethnobiol Ethnomed 2021 Apr 8;17(1):26. Epub 2021 Apr 8.

Guangdong Key Laboratory for Innovative Development and Utilization of Forest Plant Germplasm, College of Forestry and Landscape Architecture, South China Agricultural University, Guangzhou, China.

Background: Medicinal plants are the fundamental unit of traditional medicine system in Nepal. Nepalese people are rich in traditional medicine especially in folk medicine (ethnomedicine), and this system is gaining much attention after 1995. The use of medicinal plants has increased during the COVID-19 pandemic as a private behavior (not under the control of government). Read More

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Public health practitioner perspectives on dealing with measles outbreaks if high anti-vaccination sentiment is present.

BMC Public Health 2021 04 9;21(1):578. Epub 2021 Apr 9.

Australian Centre for Health Engagement, Evidence & Values (ACHEEV), School of Health and Society, Faculty of the Arts, Social Sciences & Humanities, University of Wollongong, Northfields Ave, Wollongong, NSW, Australia.

Background: Communities with low vaccination rates are at greater risk during outbreaks of vaccine preventable diseases. Most Australian parents support vaccines, but some refuse and are often judged harshly by their community, especially during an outbreak. We sought the perspectives of Australian public health experts on the key issues faced when managing a measles outbreak in an area with high anti-vaccination sentiment. Read More

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Common low complexity regions for SARS-CoV-2 and human proteomes as potential multidirectional risk factor in vaccine development.

BMC Bioinformatics 2021 Apr 8;22(1):182. Epub 2021 Apr 8.

Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Warsaw, Poland.

Background: The rapid spread of the COVID-19 demands immediate response from the scientific communities. Appropriate countermeasures mean thoughtful and educated choice of viral targets (epitopes). There are several articles that discuss such choices in the SARS-CoV-2 proteome, other focus on phylogenetic traits and history of the Coronaviridae genome/proteome. Read More

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Validity and reliability of Turkish version of Beliefs About Third-Hand Smoke Scale: BATHS-T.

Cent Eur J Public Health 2021 03;29(1):56-61

Family Medicine Department, Meram Medical Faculty, Necmettin Erbakan University, Konya, Turkey.

Objective: Exposure to third-hand smoke (THS) poses health risk, especially for children. THS is mostly ignored in Turkey. The aim of this study is to adapt the Beliefs about Third-Hand Smoke (BATHS) scale to Turkish. Read More

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Rubella and tick-borne encephalitis vaccination rates among staff and students at Austrian University of Applied Sciences.

Cent Eur J Public Health 2021 Mar;29(1):18-22

University of Applied Sciences Wiener Neustadt, Wiener Neustadt, Austria.

Objectives: Rubella and tick-borne encephalitis (TBE) are infectious diseases caused by viruses. Rubella is an air-borne infection. TBE, on the other hand, is transmitted by virus-infected ticks. Read More

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Annual influenza vaccination effect on the susceptibility to COVID-19 infection.

Cent Eur J Public Health 2021 Mar;29(1):14-17

Infectious Diseases Department, Bakirkoy Dr. Sadi Konuk Training and Research Hospital, University of Health Sciences, Istanbul, Turkey.

Objectives: We aimed to study the effect of seasonal influenza (flu) vaccination on the susceptibility to coronavirus disease 2019 (COVID-19).

Methods: A total of 203 healthcare workers of a pandemic centre of Istanbul, Turkey, were included in this retrospective study. According to the presence or absence of flu vaccination, participants were divided into group 1 and group 2. Read More

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