116 results match your criteria cross-cutting opportunities

Advancing precision public health using human genomics: examples from the field and future research opportunities.

Genome Med 2021 Jun 1;13(1):97. Epub 2021 Jun 1.

Department of Behavioral Social and Health Education Sciences, Rollins School of Public Health, Emory University, 1518 Clifton Road, Atlanta, GA, 30322, USA.

Precision public health is a relatively new field that integrates components of precision medicine, such as human genomics research, with public health concepts to help improve population health. Despite interest in advancing precision public health initiatives using human genomics research, current and future opportunities in this emerging field remain largely undescribed. To that end, we provide examples of promising opportunities and current applications of genomics research within precision public health and outline future directions within five major domains of public health: biostatistics, environmental health, epidemiology, health policy and health services, and social and behavioral science. Read More

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Perceived barriers to the adoption of active surveillance in low-risk prostate cancer: a qualitative analysis of community and academic urologists.

BMC Cancer 2021 May 31;21(1):649. Epub 2021 May 31.

American Board of Urology, Charlottesville, VA, USA.

Background: Clinical practice guidelines recommend active surveillance as the preferred treatment option for low-risk prostate cancer, but only a minority of eligible men receive active surveillance, and practice variation is substantial. The aim of this study is to describe barriers to urologists' recommendation of active surveillance in low-risk prostate cancer and explore variation of barriers by setting.

Methods: We conducted semi-structured interviews among 22 practicing urologists, evenly distributed between academic and community practice. Read More

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HIV and mental health among young people in low-resource contexts in Southeast Asia: A qualitative investigation.

Glob Public Health 2021 May 12:1-15. Epub 2021 May 12.

VOICES-Thailand Foundation, Chiang Mai, Thailand.

Young people aged 15-24 years comprise one-fourth of incident HIV infections in Southeast Asia. Given the high prevalence and impact of mental health issues among young people, we explored intersections of HIV and mental health, with a focus on adolescent and young key populations (AYKP) in Indonesia, the Philippines, Thailand, and Vietnam. Sixteen focus group discussions (4/country) with young people ( = 132; 16-24 years) and 41 key informant interviews with multisectoral HIV experts explored young people's lived experiences and unmet needs, existing programmes, and strategic directions for local and regional HIV responses. Read More

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The FDA Oncology Center of Excellence Scientific Collaborative: Charting a Course for Applied Regulatory Science Research in Oncology.

Clin Cancer Res 2021 Apr 28. Epub 2021 Apr 28.

Office of Oncology Drug Products, United States Food and Drug Administration.

The FDA Oncology Center of Excellence (OCE) is a leader within the agency in scientific outreach activities and regulatory science research. Based on analysis of scientific workshops, internal meetings and publications, the OCE identified nine scientific priority areas and one cross-cutting area of high interest for collaboration with external researchers. This paper describes the process for identifying these scientific interest areas and highlights funded and unfunded opportunities for external researchers to work with FDA staff on critical regulatory science challenges. Read More

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Advancing per- and polyfluoroalkyl substances (PFAS) research: an overview of ATSDR and NCEH activities and recommendations.

J Expo Sci Environ Epidemiol 2021 Apr 1. Epub 2021 Apr 1.

Agency for Toxic Substances and Disease Registry, Atlanta, Georgia.

The National Center for Environmental Health (NCEH), part of the Centers for Disease Control and Prevention (CDC), and the Agency for Toxic Substances and Disease Registry (ATSDR) support and conduct research advancing national, state, and local public health response to per- and polyfluoroalkyl substances (PFAS). PFAS are a group of manufactured chemicals used in industry and consumer products that persist in the environment. Given the growing evidence linking PFAS with adverse health effects in humans, NCEH and ATSDR developed a public health research framework to capture the broad range of PFAS research activities being conducted and supported by the agency to determine future research priorities and identify opportunities for interagency collaboration. Read More

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How Public Libraries Help Immigrants Adjust to Life in a New Country: A Review of the Literature.

Health Promot Pract 2021 Mar 31:15248399211001064. Epub 2021 Mar 31.

Drexel University, Philadelphia, PA, USA.

Public library programs and services offer opportunities to help immigrants navigate daily life in unfamiliar surroundings and a new language. For example, language classes address the social determinants of health as they encourage social participation and community ties and help develop friendships. The purpose of this research was to conduct a narrative literature review to understand how immigrants use public libraries and how public library services influence the social determinants of health for immigrant populations. Read More

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Nutrition competencies for medicine: an integrative review and critical synthesis.

BMJ Open 2021 03 25;11(3):e043066. Epub 2021 Mar 25.

School of Medicine, University of Wollongong, and Illawarra Health & Medical Research Institute, Wollongong, New South Wales, Australia.

Objective: Globally, 11 million deaths are attributable to suboptimal diet annually, and nutrition care has been shown to improve health outcomes. While medically trained clinicians are well-placed to provide nutrition care, medical education remains insufficient to support clinicians to deliver nutrition advice as part of routine clinical practice. Competency standards provide a framework for workforce development and a vehicle for aligning health priorities with the values of a profession. Read More

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The importance of soft skills development in a hard data world: learning from interviews with healthcare leaders.

BMC Med Educ 2021 Mar 6;21(1):147. Epub 2021 Mar 6.

VA Office of Patient Care Services, Primary Care Analytics Team-Iowa City, Iowa City VA Health Care System, Iowa City, IA, USA.

Background: Learning healthcare systems have invested heavily in training primary care staff to provide care using patient-centered medical home models, but less is known about how to effectively lead such teams to deliver high quality care. Research is needed to better understand which healthcare leadership skills are most utilized or in need of development through additional training.

Method: Semi-structured telephone interviews with healthcare leaders familiar with Patient-Aligned Care Teams (PACT) implementation in the U. Read More

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Population differences in vaccine responses (POPVAC): scientific rationale and cross-cutting analyses for three linked, randomised controlled trials assessing the role, reversibility and mediators of immunomodulation by chronic infections in the tropics.

BMJ Open 2021 02 16;11(2):e040425. Epub 2021 Feb 16.

Immunomodulation and Vaccines Programme, Medical Research Council/Uganda Virus Research Institute and London School of Hygiene and Tropical Medicine (MRC/UVRI and LSHTM) Uganda Research Unit, Entebbe, Uganda.

Introduction: Vaccine-specific immune responses vary between populations and are often impaired in low income, rural settings. Drivers of these differences are not fully elucidated, hampering identification of strategies for optimising vaccine effectiveness. We hypothesise that urban-rural (and regional and international) differences in vaccine responses are mediated to an important extent by differential exposure to chronic infections, particularly parasitic infections. Read More

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February 2021

Lessons from the Field: Integrated survey methodologies for neglected tropical diseases.

Trans R Soc Trop Med Hyg 2021 Jan;115(2):124-126

Neglected, Tropical, and Vector-Borne Diseases Unit, Communicable Diseases and Environmental Determinants of Health Department, Pan American Health Organization, Washington, D.C. 20037, USA.

The 2021-2030 Neglected Tropical Diseases road map calls for intensified cross-cutting approaches. By moving away from vertical programming, the integration of platforms and intervention delivery aims to improve efficiency, cost-effectiveness and programme coverage. Drawing on the direct experiences of the authors, this article outlines key elements for successful integrated surveys, the challenges encountered, as well as future opportunities and threats to such surveys. Read More

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January 2021

Development of a managed clinical network for children's palliative care - a qualitative evaluation.

BMC Palliat Care 2021 Jan 22;20(1):20. Epub 2021 Jan 22.

Department of Health Sciences, University of York, York, UK.

Background: Consistent evidence suggests that children's palliative care is not equitable and managed clinical networks (MCNs) have been recommended as a solution. This study explored the perspectives of health professionals involved in the development of a children's palliative care MCN, with an aim to identify barriers and enablers of successful implementation.

Methods: Thematic analysis of semi-structured interviews and focus groups with 45 healthcare staff with a role in developing the MCN or in the delivery of children's palliative care (September 2019-March 2020). Read More

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January 2021

Opportunities for Next-Generation Luminescent Materials through Artificial Intelligence.

J Phys Chem Lett 2021 Jan 10;12(2):764-772. Epub 2021 Jan 10.

Department of Chemistry, University of Houston, Houston, Texas 77204, United States.

Luminescent materials are continually sought for application in solid-state LED-based lighting and display applications. This has traditionally required extensive experimental effort. More recently, the employment of data-driven approaches in materials science has provided an alternative avenue to accelerate the discovery and development of luminescent materials. Read More

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January 2021

Top priorities for the next decade of nursing health services research.

Nurs Outlook 2021 May-Jun;69(3):265-275. Epub 2020 Dec 29.

Martha S. Pitzer Center for Women, Children, and Youth, The Ohio State University College of Nursing, Columbus, OH.

Background: The U.S. health care system faces increasing pressures for reform. Read More

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December 2020

Health care workers' experiences with implementation of "screen and treat" for cervical cancer prevention in Malawi: A qualitative study.

Implement Sci Commun 2020 Dec 14;1(1):112. Epub 2020 Dec 14.

University of California Geffen School of Medicine, Los Angeles, CA, USA.

Background: Cervical cancer remains a major cause of mortality and morbidity in low- and middle-income countries, despite the availability of effective prevention approaches. "Screen and treat" (a single-visit strategy to identify and remove abnormal cervical cells) is the recommended secondary prevention approach in low-resource settings, but there has been relatively scarce robust implementation science evidence on barriers and facilitators to providing "screen and treat" from the provider perspective, or about thermocoagulation as a lesion removal technique.

Methods: Informed by the Consolidated Framework for Implementation Research (CFIR), we conducted interviews with ten experienced "screen and treat" providers in Malawi. Read More

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December 2020

Integrated survey methodologies for neglected tropical diseases.

Trans R Soc Trop Med Hyg 2020 Dec 10. Epub 2020 Dec 10.

Neglected, Tropical, and Vector-Borne Diseases Unit, Communicable Diseases and Environmental Determinants of Health Department, Pan American Health Organization, Washington, D.C. 20037, USA.

The 2021-2030 Neglected Tropical Diseases road map calls for intensified cross-cutting approaches. By moving away from vertical programming, the integration of platforms and intervention delivery aims to improve efficiency, cost-effectiveness and programme coverage. Drawing on the direct experiences of the authors, this article outlines key elements for successful integrated surveys, the challenges encountered, as well as future opportunities and threats to such surveys. Read More

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December 2020

Creativity, serendipity, and collaboration: Cross-cutting features of successful task-sharing in comprehensive safe abortion care.

Int J Gynaecol Obstet 2020 Jul;150 Suppl 1:49-54

Independent Consultant in Reproductive and Sexual Health, Mexico City, Mexico.

Limited capacity to deliver comprehensive safe abortion care and shortages in trained healthcare providers contribute to a lack of access to safe services. The World Health Organization published guidelines and recommendations on expanding health worker roles through task-sharing as one way to address disparities. A multicountry case study was conducted in six diverse contexts (Bangladesh, Colombia, Ghana, Mexico City in Mexico, Sweden, and Tunisia) to determine the cross-cutting strategies that enabled inclusion of a broader range of healthcare workers in comprehensive safe abortion care. Read More

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Reexamining Health-Care Coalitions in Light of COVID-19.

Disaster Med Public Health Prep 2020 Nov 4:1-5. Epub 2020 Nov 4.

The National Center for Disaster Medicine and Public Health and the Department of Military & Emergency Medicine, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA.

The national response to the coronavirus disease 2019 (COVID-19) pandemic has highlighted critical weaknesses in domestic health care and public health emergency preparedness, despite nearly 2 decades of federal funding for multiple programs designed to encourage cross-cutting collaboration in emergency response. Health-care coalitions (HCCs), which are funded through the Hospital Preparedness Program, were first piloted in 2007 and have been continuously funded nationwide since 2012 to support broad collaborations across public health, emergency management, emergency medical services, and the emergency response arms of the health-care system within a geographical area. This commentary provides a SWOT (strengths, weaknesses, opportunities, and threats) analysis to summarize the strengths, weaknesses, opportunities, and threats related to the current HCC model against the backdrop of COVID-19. Read More

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November 2020

Public involvement in the governance of population-level biomedical research: unresolved questions and future directions.

J Med Ethics 2020 Oct 6. Epub 2020 Oct 6.

Research Institute for Ethics and Law, Swansea University, Swansea, UK.

Population-level biomedical research offers new opportunities to improve population health, but also raises new challenges to traditional systems of research governance and ethical oversight. Partly in response to these challenges, various models of public involvement in research are being introduced. Yet, the ways in which public involvement should meet governance challenges are not well understood. Read More

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October 2020

Making the UN Decade on Ecosystem Restoration a Social-Ecological Endeavour.

Trends Ecol Evol 2021 01 18;36(1):20-28. Epub 2020 Sep 18.

Faculty of Sustainability, Leuphana University Lueneburg, Universitätsallee 1, 21335 Lueneburg, Germany.

The United Nations (UN) recently declared 2021 to 2030 the Decade on Ecosystem Restoration. Against this background, we review recent social-ecological systems research and summarize key themes that could help to improve ecosystem restoration in dynamic social contexts. The themes relate to resilience and adaptability, ecosystem stewardship and navigation of change, relational values, the coevolution of human and ecological systems, long-range social-ecological connections, and leverage points for transformation. Read More

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January 2021

Secondary Traumatic Stress in Ob-Gyn: A Mixed Methods Analysis Assessing Physician Impact and Needs.

J Surg Educ 2021 May-Jun;78(3):1024-1034. Epub 2020 Sep 15.

Medical College of Wisconsin, Milwaukee, Wisconsin.

Objective: This study aims to evaluate the incidence of secondary traumatic stress in Obstetrics and Gynecology physicians including symptoms, impact, and programmatic needs for support.

Design: This study used a mixed-methods approach comprised of an anonymous online survey and individual interviews/focus groups. IBM SPSS 24. Read More

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September 2020

A qualitative study reporting maternal perceptions of the importance of play for healthy growth and development in the first two years of life.

BMC Pediatr 2020 09 9;20(1):428. Epub 2020 Sep 9.

SAMRC/Wits Developmental Pathways for Health Research Unit, Department of Paediatrics and Child Health, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.

Background: In order for infants and toddlers to meet recommended movement guidelines, their caregivers need to encourage play daily. This study used a qualitative approach to understand how mothers perceive and promote play and physical activity during the first 2 years of life.

Methods: Mothers with children between 0 and 24 months were recruited from the SAMRC/Wits Developmental Pathways for Health Research Unit in Soweto, South Africa. Read More

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September 2020

Unlocking challenges and opportunities presented by COVID-19 pandemic for cross-cutting disruption in agri-food and green deal innovations: Quo Vadis?

Sci Total Environ 2020 Dec 31;748:141362. Epub 2020 Jul 31.

Research & Innovation Department, Galanakis Laboratories, Chania, Greece; College of Science, King Saud University, Riyadh, Saudi Arabia; Food Waste Recovery Group, ISEKI Food Association, Vienna, Austria.

COVID-19 pandemic is on a trajectory to cause catastrophic global upheaval with the potential to alter geopolitical and socio-economic norms. Many countries are frantically responding with staggering financial stimulus recovery initiatives. This opinion-paper reviews challenges, opportunities, and potential solutions for the post-COVID-19 era that focuses on intensive sustaining of agri-food supply chain in tandem with meeting the high demand for new green deal innovation. Read More

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December 2020

Gambling harm is everybody's business: A public health approach and call to action.

P Johnstone M Regan

Public Health 2020 Jul 17;184:63-66. Epub 2020 Jul 17.

Public Health England, UK. Electronic address:

There is a growing consensus that gambling is a public health issue and that preventing gambling related harms requires a broad response. Although many policy decisions regarding gambling are made at a national level in the UK, there are clear opportunities to take action at local and regional levels to prevent the negative impacts on individuals, families and local communities. This response goes beyond the statutory roles of licencing authorities to include amongst others the National Health Service (NHS), the third sector, mental health services, homelessness and housing services, financial inclusion support. Read More

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MOF-Based Membranes for Gas Separations.

Chem Rev 2020 08 1;120(16):8161-8266. Epub 2020 Jul 1.

Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, United States.

Metal-organic frameworks (MOFs) represent the largest known class of porous crystalline materials ever synthesized. Their narrow pore windows and nearly unlimited structural and chemical features have made these materials of significant interest for membrane-based gas separations. In this comprehensive review, we discuss opportunities and challenges related to the formation of pure MOF films and mixed-matrix membranes (MMMs). Read More

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Is nutrition science ready for the twenty-first century? Moving towards transdisciplinary impacts in a changing world.

Eur J Nutr 2020 May;59(Suppl 1):1-10

De Vries Nutrition Solutions, Gorssel, The Netherlands.

Malnutrition in an obese world was the fitting title of the 13th Federation of European Nutrition Societies (FENS) conference held in October 2019. Many individuals do not eat a healthy, well-balanced diet, and this is now understood to be a major driver of increased disease risk and illness. Moreover, both our current eating patterns and the food system as a whole are environmentally unsustainable, threatening the planetary systems we depend on for survival. Read More

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Drivers of opioid use in Appalachian Pennsylvania: Cross-cutting social and community-level factors.

Int J Drug Policy 2020 04 6;78:102706. Epub 2020 Mar 6.

Department of Behavioral and Community Health Sciences, University of Pittsburgh Graduate School of Public Health, 130 De Soto St, Pittsburgh, PA 15261, United States; Center for Social Dynamics and Community Health, University of Pittsburgh Graduate School of Public Health, 130 De Soto St, Pittsburgh, PA 15261, United States.

Background: Four Appalachian states including Pennsylvania (PA) have the highest drug overdose rates in the country, calling for better understanding of the social and economic drivers of opioid use in the region. Using key informant interviews, we explored the social and community drivers of opioid use in a non-urban Appalachian Pennsylvania community.

Methods: In 2017, we conducted qualitative interviews with 20 key stakeholders from a case community selected using the results from quantitative spatial models of hospitalizations for opioid use disorders. Read More

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Challenges for accessing and maintaining good quality of HIV care among men who have sex with men living with HIV in China: a qualitative study with key stakeholders.

AIDS Care 2020 05 9;32(sup2):119-126. Epub 2020 Mar 9.

Department of Health Behavior, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.

HIV care in China is shifting toward a community-based model involving a wide range of stakeholders. We aimed to understand key stakeholders' perceived challenges of providing high-quality care for men who have sex with men (MSM) living with HIV. In-depth interviews were conducted with a diverse sample of stakeholders ( = 17) in two Chinese cities, including providers, policymakers, and community workers. Read More

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Common issues related to children's environmental health in the Asia-Pacific region.

Rev Environ Health 2020 Mar;35(1):3-8

Chulabhorn Research Institute, Bangkok, Thailand.

This summary reports on the outcomes and common issues faced among the countries represented at the Asia-Pacific Regional Meeting on Children's Environmental Health, a meeting that was held at the Chulabhorn Research Institute in Bangkok, Thailand, and which focused on cross-cutting issues and commonalities among countries/regions, discussion of lessons learnt, exploring opportunities for policy-relevant research collaborations, and reviewing available educational tools to help translate research findings into tangible outputs. The common children's environmental health issues faced by countries in the Asia-Pacific region include indoor and outdoor air pollution; unregulated and inadequate waste management; chemical and infectious agents in water used for drinking and cooking; hazardous pesticide use; and climate change and extreme weather events. The meeting participants agreed there is a need for multisectoral involvement in each country to develop frameworks and guidelines, raising public awareness of risk, and managing exposures in order to tackle these common issues. Read More

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Cancer and changes in facial appearance: A meta-ethnography of qualitative studies.

Br J Health Psychol 2020 02 2;25(1):129-151. Epub 2020 Jan 2.

School of Clinical Dentistry, University of Sheffield, UK.

Introduction: Living with an altered facial appearance as a result of treatment for cancer requires considerable psychological adjustment. As such it is essential that health care professionals understand the lived experience of people affected. This systematic review provides a meta-ethnography of studies that have explored the experience of changed facial appearance as a result of cancer. Read More

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February 2020

Urban health: an example of a "health in all policies" approach in the context of SDGs implementation.

Global Health 2019 12 18;15(1):87. Epub 2019 Dec 18.

Barcelona Institute for Global Health, ISGlobal, Barcelona, Spain.

Background: Cities are an important driving force to implement the Sustainable Development Goals (SDGs) and the New Urban Agenda. The SDGs provide an operational framework to consider urbanization globally, while providing local mechanisms for action and careful attention to closing the gaps in the distribution of health gains. While health and well-being are explicitly addressed in SDG 3, health is also present as a pre condition of SDG 11, that aims at inclusive, safe, resilient and sustainable cities. Read More

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December 2019