258,326 results match your criteria covid-19 pandemic

Improving the Telemedicine Evaluation of Patients With Acute Vision Loss: A Call to Eyes.

Neurology 2022 Jun 28. Epub 2022 Jun 28.

Departments of Neurology and Ophthalmology, Mayo Clinic College of Medicine and Science, Phoenix, Arizona.

Acute vision loss related to cerebral or retinal ischemia is a time-sensitive emergency with potential treatment options including intravenous or intraarterial thrombolysis and mechanical thrombectomy. However, patients either present in delayed fashion or present to an emergency department that lacks the subspecialty expertise to recognize and treat these conditions in a timely fashion. Moreover, healthcare systems in the United States are becoming increasingly reliant on telestroke and teleneurology services for acute neurologic care, making accurate diagnosis of acute vision loss even more challenging due to critical limitations to the remote video evaluation, including the inability to perform routine ophthalmoscopy. Read More

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Immune Responses after a Third Dose of mRNA Vaccine Differ in Virus-Naive versus SARS-CoV-2-Recovered Dialysis Patients.

Clin J Am Soc Nephrol 2022 Jun 28. Epub 2022 Jun 28.

Assistance Publique-Hôpitaux de Paris, Hôpitaux Universitaires Henri Mondor, Department of Nephrology, Centre de Référence Maladie Rare Syndrome Néphrotique Idiopathique, Fédération Hospitalo-Universitaire Innovative Therapy for Immune Disorders, Creteil, France.

Background And Objectives: After two doses of mRNA vaccine against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), patients on dialysis show a defective humoral response, but a third dose could increase anti-SARS-CoV-2 spike IgG titers. Responses could be different in virus-naive and SARS-CoV-2-recovered patients on dialysis. However, characterization of memory B cell response after three doses is lacking. Read More

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Patient safety friendly hospital standards and customer orientation among Iranian nurses during the COVID-19 pandemic.

BMJ Open Qual 2022 Jun;11(2)

Intensive Care and Management, School of Nursing and Midwifery, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran.

Background: The quality of health services is determined on the basis of meeting customers' needs and expectations. Due to the COVID-19 pandemic, health systems have faced high degrees of uncertainty as well as a variety of challenges. Thus, this study aimed to investigate the relationship between patient safety friendly hospital standards and customer orientation among Iranian nurses during the COVID-19 pandemic. Read More

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Learning from COVID-19 to prevent and prepare for pandemics in the Eastern Mediterranean Region.

BMJ Glob Health 2022 Jun;7(Suppl 4)

Alliance for Health Policy and Systems Research, World Health Organization, Geneve, Switzerland.

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Inequities in the deployment of COVID-19 vaccine in the WHO Eastern Mediterranean Region, 2020-2021.

BMJ Glob Health 2022 Jun;7(Suppl 4)

DCD, WHO Regional Office for the Eastern Mediterranean, Cairo, Egypt.

The WHO Eastern Mediterranean Region (EMR) is characterised by a large range in routine immunisation coverage. We reviewed progress in access, deployment efforts, and use of COVID-19 vaccines in the EMR to identify bottlenecks and propose recommendations. We compiled and analysed data reported to WHO regarding the number of vaccines provided emergency use authorisation (EUA) in each country, the number of vaccine doses allocated and delivered by COVAX, the number of vaccine doses received bilaterally, the date of initiation of vaccination, vaccine usage rate and overall vaccination coverage. Read More

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Usage of social media in epidemic intelligence activities in the WHO, Regional Office for the Eastern Mediterranean.

BMJ Glob Health 2022 Jun;7(Suppl 4)

WHO Health Emergencies Programme, WHO Regional Office for the Eastern Mediterranean, Cairo, Egypt.

Social media platforms are a massive source of information being used for monitoring and detecting various actual events such as natural disasters and disease outbreaks. This paper aims to present the experience of WHO, Regional Office for the Eastern Mediterranean in using social media for the detection and monitoring of COVD-19 pandemic alongside the other event-based surveillance tools. Over the period of 29 January 2020 to 31 May 2021, information was collected from social media and other media outlets (web news) as being the source of health information for early detecting and monitoring the situation of COVID-19 events. Read More

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Influenza activity in the Eastern Mediterranean Region (EMR) in 2020-2021 amidst the COVID-19 pandemic.

BMJ Glob Health 2022 Jun;7(Suppl 4)

Infectious Hazard Prevention and Preparedness, World Health Organization- Eastern Mediterranean Regional Office, Cairo, Egypt

Introduction: A global reduction in influenza virus activity during the COVID-19 pandemic has been observed, including in the Eastern Mediterranean Region (EMR). However, these changes have not been thoroughly evaluated scientifically in the EMR.

Objective: We aim to present data on seasonal influenza activity during the pre-pandemic period (2016-2019) and compare it to the pandemic period (2020-2021) in EM countries. Read More

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Public health emergency operation centres: status, gaps and areas for improvement in the Eastern Mediterranean Region.

BMJ Glob Health 2022 Jun;7(Suppl 4)

WHO Health Emergency Programme (WHE), World Health Organisation Regional Office for the Eastern Mediterranean, Cairo, Egypt.

The functionality of Public Health Emergency Operations Centres (PHEOCs) in countries is vital to their response capacity. The article assesses the status of National PHEOCs in the 22 countries of the Eastern Mediterranean Region. We designed and administered an online survey between May and June 2021. Read More

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Predictors of Respiratory Support Use in Emergency Department Patients With COVID-19-Related Respiratory Failure.

Respir Care 2022 Jun 28. Epub 2022 Jun 28.

Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York; and Department of Emergency Medicine, Icahn School of Medicine at Mount Sinai, New York, New York.

Background: Given the known downstream implications of choice of respiratory support on patient outcomes, all factors influencing these decisions, even those not limited to the patient, warrant close consideration. We examined the effect of emergency department (ED)-specific system factors, such as work load and census, on the use of noninvasive versus invasive respiratory support.

Methods: We conducted a multi-center retrospective cohort study of all adult subjects with severe COVID-19 requiring an ICU admission from 5 EDs within a single urban health care system. Read More

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Community, Risk Assessment, Prevention and Control: Black American College Student's Information Seeking on COVID-19.

Health Info Libr J 2022 Jun 28. Epub 2022 Jun 28.

School of Library & Information Science, Louisiana State University, Baton Rouge, USA.

Background: Despite the disproportionate impact of the novel coronavirus on Black Americans, there is little research that centres Black college students' information behaviours during the pandemic.

Objective: The objective of this study is to identify information needs, resources and use regarding the novel coronavirus pandemic among Black American college students.

Methods: This is a quantitative study among 389 college students in the USA. Read More

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High frequency of neutralizing antibodies to type I Interferon in HIV-1 patients hospitalized for COVID-19.

Clin Immunol 2022 Jun 25:109068. Epub 2022 Jun 25.

Department of Molecular Medicine, Laboratory of Virology, Sapienza University of Rome, Viale di Porta Tiburtina n° 28, 00185 Rome, Italy. Electronic address:

The presence of anti-IFN neutralizing antibodies (NAB) has been reported in critically ill COVID-19 patients. We found that 87.5% (7/8) of HIV-1 patients co-infected with SARS-CoV-2 had serum anti-IFN-I NAB against IFN-α subtypes, IFN-β and/or IFN-ω. Read More

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Altered brain regional homogeneity is associated with depressive symptoms in COVID-19.

J Affect Disord 2022 Jun 25. Epub 2022 Jun 25.

Neuroradiology Unit, Neurosciences Department, University of Padova, Azienda Ospedale-Università Padova, Padua, Italy.

Background: COVID-19 is an infectious disease that has spread worldwide in 2020, causing a severe pandemic. In addition to respiratory symptoms, neuropsychiatric manifestations are commonly observed, including chronic fatigue, depression, and anxiety. The neural correlates of neuropsychiatric symptoms in COVID-19 are still largely unknown. Read More

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COVID-19 Booster Exemption for Severe Dyshidrotic Eczema.

J Am Acad Dermatol 2022 Jun 25. Epub 2022 Jun 25.

Department of Dermatology, University of Connecticut School of Medicine, Conn Health, Farmington, CT; Department of Dermatology, University of Florida College of Medicine, Gainesville, FL. Electronic address:

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Admission Code Status and End-of-life Care for Hospitalized Patients with COVID-19.

J Pain Symptom Manage 2022 Jun 25. Epub 2022 Jun 25.

Cambia Palliative Care Center of Excellence, University of Washington, Seattle, WA, USA; Department of Anesthesiology and Pain Medicine, University of Washington, Seattle, WA, USA.

Context: The COVID-19 pandemic has highlighted variability in intensity of care. We aimed to characterize intensity of care among hospitalized patients with COVID-19.

Objectives: Examine the prevalence and predictors of admission code status, palliative care consultation, comfort-measures-only orders, and cardiopulmonary resuscitation (CPR) among patients hospitalized with COVID-19. Read More

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Palliative Care Impact on COVID-19 Patients Requiring Extracorporeal Membrane Oxygenation.

J Pain Symptom Manage 2022 Jun 25. Epub 2022 Jun 25.

Department of Management, Policy, and Community Health (MPACH), University of Texas School of Public Health; UTHealth Consortium on Aging; and VA Center of Innovations, DeBakey VA Medical Center, Houston, Texas USA.

Context: Patients with severe respiratory failure from COVID-19 refractory to conventional therapies may be treated with extracorporeal membrane oxygenation (ECMO). ECMO requirement is associated with high mortality and prolonged hospital course. ECMO is a high-resource intervention with significant burdens placed on caregivers and families with limited data on the integration of palliative care consultation (PCC). Read More

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ABO blood group and link to COVID-19: A comprehensive review of the reported associations and their possible underlying mechanisms.

Microb Pathog 2022 Jun 25:105658. Epub 2022 Jun 25.

Superior Institute of Biomedical Sciences, State University of Ceará, Dr. Silas Munguba Av., Fortaleza, 60714-903, Ceará, Brazil.

ABO blood group is long known to be an influencing factor for the susceptibility to infectious diseases, and many studies have been describing associations between ABO blood types and COVID-19 infection and severity, with conflicting findings. This narrative review aims to summarize the literature regarding associations between the ABO blood group and COVID-19. Blood type O is mostly associated with lower rates of SARS-CoV-2 infection, while blood type A is frequently described as a risk factor. Read More

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A regional command centre for pandemic surge.

Chest 2022 Jun 25. Epub 2022 Jun 25.

Sistema d'Emergències Mèdiques de Catalunya, Barcelona, Spain; Faculty of Medicine, University of Barcelona, Spain.

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Wastewater-based epidemiology in countries with poor wastewater treatment - Epidemiological indicator function of SARS-CoV-2 RNA in surface waters.

Sci Total Environ 2022 Jun 25:156964. Epub 2022 Jun 25.

University of Belgrade, Institute for Biological Research "Siniša Stanković", National Institute of the Republic of Serbia, Bulevar despota Stefana 142, 11060 Belgrade, Serbia.

Wastewater-based epidemiology (WBE) surveillance of COVID-19 and other future outbreaks is a challenge for developing countries as most households are not connected to a sewerage system. In December 2019, SARS-CoV-2 RNA was detected in the Danube River at a site severely affected by wastewaters from Belgrade. Rivers are much more complex systems than wastewater systems, and efforts are needed to address all the factors influencing the adoption of WBE as an alternative to targeting raw wastewater. Read More

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High frequency of anti-DSG 2 antibodies in post COVID-19 serum samples.

J Mol Cell Cardiol 2022 Jun 25. Epub 2022 Jun 25.

National Heart Centre, Singapore; Sengkang General Hospital, Singapore.

High frequency of anti-DSG 2 antibodies in post COVID 19 serum samples background: There is growing recognition that COVID-19 does cause cardiac sequelae. The underlying mechanisms involved are still poorly understood to date. Viral infections, including COVID-19, have been hypothesized to contribute to autoimmunity, by exposing previously hidden cryptic epitopes on damaged cells to an activated immune system. Read More

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Recent advances in aqueous virus removal technologies.

Chemosphere 2022 Jun 25:135441. Epub 2022 Jun 25.

Université de Lorraine, Laboratoire de Physique et Chimie Théoriques LPCT UMR CNRS, 7019, Nancy, France. Electronic address:

The COVID-19 outbreak has triggered a massive research, but still urgent detection and treatment of this virus seems a public concern. The spread of viruses in aqueous environments underlined efficient virus treatment processes as a hot challenge. This review critically and comprehensively enables identifying and classifying advanced biochemical, membrane-based and disinfection processes for effective treatment of virus-contaminated water and wastewater. Read More

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Humoral and cellular immune memory to four COVID-19 vaccines.

Cell 2022 May 27. Epub 2022 May 27.

Center for Infectious Disease and Vaccine Research, La Jolla Institute for Immunology (LJI), La Jolla, CA 92037, USA; Department of Medicine, Division of Infectious Diseases and Global Public Health, University of California, San Diego (UCSD), La Jolla, CA 92037, USA. Electronic address:

Multiple COVID-19 vaccines, representing diverse vaccine platforms, successfully protect against symptomatic COVID-19 cases and deaths. Head-to-head comparisons of T cell, B cell, and antibody responses to diverse vaccines in humans are likely to be informative for understanding protective immunity against COVID-19, with particular interest in immune memory. Here, SARS-CoV-2-spike-specific immune responses to Moderna mRNA-1273, Pfizer/BioNTech BNT162b2, Janssen Ad26. Read More

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A new perspective: Practice-enhancing publications about the ambulatory care medication-use process in 2020.

Am J Health Syst Pharm 2022 Jun 28. Epub 2022 Jun 28.

University of North Carolina at Chapel Hill Eshelman School of Pharmacy, Chapel Hill, NC, and University of North Carolina Medical Center, Chapel Hill, NC, USA.

Disclaimer: In an effort to expedite the publication of articles related to the COVID-19 pandemic, AJHP is posting these manuscripts online as soon as possible after acceptance. Accepted manuscripts have been peer-reviewed and copyedited, but are posted online before technical formatting and author proofing. These manuscripts are not the final version of record and will be replaced with the final article (formatted per AJHP style and proofed by the authors) at a later time. Read More

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Comparison of mortality patterns after the fukushima daiichi nuclear power plant radiation disaster and during the COVID-19 pandemic.

J Radiol Prot 2022 Jun 28. Epub 2022 Jun 28.

Department of Radiation Health Management, Fukushima Medical University, Fukushima, JAPAN.

The initial health impacts caused by nuclear disasters can be broadly classified into direct and indirect effects. Though no direct health hazards caused by radiation, such as acute radiation injury, were observed following the Fukushima Daiichi Nuclear Power Plant (FDNPP) accident, indirect deaths have been reported, including those caused by initial emergency evacuation and relocation, medical disruption, and psychological and social health effects. However, these indirect health effects have not been prioritised for addressal. Read More

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High-density EEG sleep correlates of cognitive and affective impairment at 12-month follow-up after COVID-19.

Clin Neurophysiol 2022 Jun 15;140:126-135. Epub 2022 Jun 15.

Department of Neuroscience, Section of Rehabilitation, University of Padova, via Giustiniani, 3, Padova 35128, Italy; Padova Neuroscience Center, University of Padova, via Orus 2/B, Padova 35129, Italy. Electronic address:

Objective: To disentangle the pathophysiology of cognitive/affective impairment in Coronavirus Disease-2019 (COVID-19), we studied long-term cognitive and affective sequelae and sleep high-density electroencephalography (EEG) at 12-month follow-up in people with a previous hospital admission for acute COVID-19.

Methods: People discharged from an intensive care unit (ICU) and a sub-intensive ward (nonICU) between March and May 2020 were contacted between March and June 2021. Participants underwent cognitive, psychological, and sleep assessment. Read More

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Policy-driven mathematical modeling for COVID-19 pandemic response in the Philippines.

Epidemics 2022 Jun 20;40:100599. Epub 2022 Jun 20.

National Institutes of Health, University of the Philippines Manila, Philippines.

Around the world, disease surveillance and mathematical modeling have been vital tools for government responses to the COVID-19 pandemic. In the face of a volatile crisis, modeling efforts have had to evolve over time in proposing policies for pandemic interventions. In this paper, we document how mathematical modeling contributed to guiding the trajectory of pandemic policies in the Philippines. Read More

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De Novo design of potential inhibitors against SARS-CoV-2 Mpro.

Comput Biol Med 2022 Jun 15;147:105728. Epub 2022 Jun 15.

Shenyang Key Laboratory of Computer Simulating and Information Processing of Bio-macromolecules, Shenyang, 110036, China; Research Center for Computer Simulating and Information Processing of Bio-macromolecules of Liaoning Province, Shenyang, 110036, China; Engineering Laboratory for Molecular Simulation and Designing of Drug Molecules of Liaoning, Shenyang, 110036, China; School of Pharmaceutical Sciences, Liaoning University, Shenyang, 110036, China. Electronic address:

The impact of the ravages of COVID-19 on people's lives is obvious, and the development of novel potential inhibitors against SARS-CoV-2 main protease (Mpro), which has been validated as a potential target for drug design, is urgently needed. This study developed a model named MproI-GEN, which can be used for the de novo design of potential Mpro inhibitors (MproIs) based on deep learning. The model was mainly composed of long-short term memory modules, and the last layer was re-trained with transfer learning. Read More

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Watch out for neuromyelitis optica spectrum disorder onset or clinical relapse after COVID-19 vaccination: What neurologists need to know?

Mult Scler Relat Disord 2022 Jun 10;65:103960. Epub 2022 Jun 10.

Multiple Sclerosis Research Center, Neuroscience Institute, Tehran University of Medical Sciences, Tehran, Iran. Electronic address:

Introduction: The ongoing global COVID-19 pandemic has dramatically impacted our lives. We conducted this systematic review to investigate the safety of the COVID-19 vaccines in NMOSD patients.

Methods: We systematically searched PubMed, Scopus, Web of Science, and Embase from the beginning of the COVID-19 vaccination to March 1, 2022. Read More

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We must learn from the COVID-19 pandemic.

Bettina Fossberg

Tidsskr Nor Laegeforen 2022 Jun 27;142(10). Epub 2022 Jun 27.

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