72,478 results match your criteria covid-19 outbreak

Building knowledge of university campus population dynamics to enhance near-to-source sewage surveillance for SARS-CoV-2 detection.

Sci Total Environ 2021 Sep 20;806(Pt 1):150406. Epub 2021 Sep 20.

Joint Biosecurity Centre, Department of Health and Social Care, Windsor House, Victoria Street, London SW1H 0TL, United Kingdom; School of Engineering, Newcastle University, Newcastle-upon-Tyne NE1 7RU, United Kingdom. Electronic address:

Wastewater surveillance has been widely implemented for monitoring of SARS-CoV-2 during the global COVID-19 pandemic, and near-to-source monitoring is of particular interest for outbreak management in discrete populations. However, variation in population size poses a challenge to the triggering of public health interventions using wastewater SARS-CoV-2 concentrations. This is especially important for near-to-source sites that are subject to significant daily variability in upstream populations. Read More

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September 2021

Centenarians exposed to the Spanish flu in their early life better survived to COVID-19.

Aging (Albany NY) 2021 Sep 27;13(undefined). Epub 2021 Sep 27.

University of Sassari, Department of Medical, Surgical and Experimental Sciences, Sassari, Italy.

Background: Although it is known that mortality due to COVID-19 increases progressively with age, the probability of dying from this serious infection among the oldest-old population is little known, and controversial data are found in literature.

Methods: We examine the mortality by year and month of birth of Belgians who had turned 100 during the current COVID-19 pandemic and whose birth fell on the years around the end the First World War and the outbreak of the H1N1 "Spanish flu" pandemic.

Findings: The COVID-19 mortality of the "older" centenarians is significantly lower than that of "younger" centenarians, and this difference between the two groups reaches a maximum on August 1, 1918 as the discriminating cut-off date of birth. Read More

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September 2021

Effectiveness of BNT162b2 Vaccine in Adolescents during Outbreak of SARS-CoV-2 Delta Variant Infection, Israel, 2021.

Emerg Infect Dis 2021 Sep 27;27(11). Epub 2021 Sep 27.

In Israel, the BNT162b2 vaccine against severe acute respiratory syndrome coronavirus 2 was approved for use in adolescents in June 2021, shortly before an outbreak of B.1.617. Read More

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September 2021

Trajectories of attitude toward own aging and subjective age from 2008 to 2020 among middle-aged and older adults: Partial evidence of a "COVID-19 effect".

Psychol Aging 2021 Sep 27. Epub 2021 Sep 27.

Heidelberg University.

As older adults have frequently been portrayed as one homogeneous and vulnerable risk group in public debates and in the media immediately after the outbreak of the Coronavirus disease (COVID-19) pandemic, a general shift toward less favorable attitude toward own aging (ATOA) might have resulted. In contrast, individuals may feel younger than before the pandemic, reflecting a psychological mechanism to avoid identifying themselves with the old age "risk group." We investigate 12-year trajectories of ATOA and subjective age among middle-aged and older German adults based on assessments between 2008 and Summer 2020 ( = 7,730; age in 2008: 40-93 years, = 62. Read More

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September 2021

Curious Binding Energy Increase between the Receptor-Binding Domain of the SARS-CoV-2 Spike Protein and Angiotensin-Converting Enzyme 2 Adsorbed on a Silane Monolayer from Molecular Dynamics Simulations.

J Phys Chem B 2021 Sep 27. Epub 2021 Sep 27.

Ecole Centrale de Lyon, CNRS, INSA Lyon, Université Claude Bernard Lyon 1, CPE Lyon, INL, UMR5270, Université de Lyon, Ecully 69130, France.

In the context of the COVID-19 outbreak since December 2019, antigenic tests are widely used, for diagnosis purposes, to detect the SARS-CoV-2 spike protein in nasopharyngeal fluid through its interactions with specific antibodies. However, the SARS-CoV-2 spike protein is subject to rapid mutations yielding more and more variants that might lose their affinity toward the currently used antibodies. The virus entry into the host cell involves interactions between the angiotensin-converting enzyme 2 (ACE2) and the SARS-CoV-2 spike protein receptor-binding domain. Read More

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September 2021

Evaluation of SARS-CoV-2 Antibodies and the Impact of COVID-19 on the HIV Care Continuum, Economic Security, Risky Health Behaviors, and Mental Health Among HIV-Infected Individuals in Vietnam.

AIDS Behav 2021 Sep 27. Epub 2021 Sep 27.

AIDS Clinical Center, National Center for Global Health and Medicine, 1-21-1, Toyama, Shinjuku, Tokyo, 162-8655, Japan.

Coronavirus disease 2019 (COVID-19) and associated social responses may uniquely affect people living with HIV (PLHIV). SARS-CoV-2 antibody testing and a cross-sectional survey on COVID-19's socio-behavioral impacts were conducted among a large PLHIV cohort in Hanoi, Vietnam. We examined anonymous antibody test results for 1243 PLHIV (99. Read More

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September 2021

Symptoms of major depressive disorder during the COVID-19 pandemic: results from a representative sample of the Canadian population.

Health Promot Chronic Dis Prev Can 2021 Sep 27;41(11). Epub 2021 Sep 27.

Department of Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, Ontario, Canada.

Introduction: Since the outbreak of COVID-19, numerous studies from around the world have reported declines in mental health. However, most of these studies were of low-to-moderate quality and many were based on convenience samples or used mental health measures with low validity, or both. Consequently, it has been difficult to draw conclusions. Read More

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September 2021

Change in subjective health status among frail older Japanese people owing to the coronavirus disease pandemic and characteristics of their responses.

Geriatr Gerontol Int 2021 Sep 27. Epub 2021 Sep 27.

Research Team for Human Care, Tokyo Metropolitan Institute of Gerontology, Tokyo, Japan.

Aim: The coronavirus disease 2019 (COVID-19) pandemic remains a major global public health issue, and it has led to restrictions in physical and social activities among community-dwelling people, including frail older adults. This study aimed to determine the impact of the pandemic on the subjective health status and characteristics of community-dwelling frail older adults by assessing their knowledge of infection, behaviors and negative psychological response.

Methods: During October 2019, 720 older adults participated in "The Otassha Study. Read More

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September 2021

Population birth data and pandemic readiness in Europe.


BJOG 2021 Sep 27. Epub 2021 Sep 27.

The SARS-CoV-2 pandemic exposed multiple shortcomings in national and international capacity to respond to an infectious disease outbreak. It is essential to learn from these deficiencies to prepare for future epidemics. One major gap is the limited availability of timely and comprehensive population-based routine data about COVID-19's impact on pregnant women and babies. Read More

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September 2021

Patient safety, quality of care and missed nursing care at a cardiology department during the COVID-19 outbreak.

Nurs Open 2021 Sep 26. Epub 2021 Sep 26.

Emergency and Reparative Medicine Theme, Karolinska University Hospital, Stockholm, Sweden.

Aim: To evaluate missed nursing care and patient safety during the first wave of the COVID-19 pandemic at in-patient cardiology wards.

Design: A cross-sectional design with a comparative approach.

Method: Registered nurses and nurse assistants at a cardiology department were invited to answer the MISSCARE Survey-Swedish version, and questions on patient safety and quality of care during the COVID-19 pandemic. Read More

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September 2021

Cardiovascular Manifestations of COVID-19: Insights into a Single-Center Experience.

TH Open 2021 Jul 9;5(3):e329-e334. Epub 2021 Aug 9.

Department of Cardiology, Hospital and University Fribourg, Fribourg, Switzerland.

 Since December 2019, an emerging outbreak of novel coronavirus disease 2019 (COVID-19) is caused by the severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2). The aim of the present report is to describe a population with elevated levels of high-sensitive cardiac troponin T (hs-cTnT) and report on their management during the pandemic of COVID-19.  In this retrospective cohort, we collected data from all patients with hs-cTnT levels of >50 ng/mL admitted to Fribourg Hospital between February 15, 2020, and April 15, 2020. Read More

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Evaluating the sensitivity of SARS-CoV-2 infection rates on college campuses to wastewater surveillance.

Infect Dis Model 2021 21;6:1144-1158. Epub 2021 Sep 21.

Applied Critical Thinking & Collaboratory for Resiliency & Recovery, Rochester Institute of Technology, Rochester, NY, 14623, USA.

As college campuses reopened in fall 2020, we saw a large-scale experiment unfold on the efficacy of various strategies to contain the SARS-CoV-2 virus. Traditional individual surveillance testing via nasal swabs and/or saliva is among the measures that colleges are pursuing to reduce the spread of the virus on campus. Additionally, some colleges are testing wastewater on their campuses for signs of infection, which can provide an early warning signal for campuses to locate COVID-positive individuals. Read More

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September 2021

Factors affecting 30-day postoperative complications after emergency surgery during the COVID-19 outbreak: A multicentre cohort study.

Int J Surg Open 2021 Sep 24;35:100397. Epub 2021 Aug 24.

Department of Surgery, Cancer Centre, University Medical Centre Utrecht, the Netherlands.

Introduction: Coronavirus disease 2019 (COVID-19) has influenced (surgical) care worldwide. Measures were taken to prioritize surgical care in order to maintain capacity for COVID-19 healthcare. However, the influence of these measures on emergency surgery is limited. Read More

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September 2021

Impact of the COVID-19 pandemic on the outcome, morbidity, and mortality of acute care surgery patients: A retrospective cohort study.

Int J Surg Open 2021 Jan 3;28:50-55. Epub 2020 Dec 3.

Division of General Surgery, Department of Surgery, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.

Background: Coronavirus disease (COVID-19) has impacted both emergency and elective surgical management owing to its highly infectious nature and the shortage of personal protective equipment. This study aimed to review the outcomes of emergency surgical conditions and trauma during the pandemic lockdown.

Material And Methods: We retrospectively reviewed and collected data from patients who attended the Acute Care Surgery Service from 1st April to May 31st, 2020 during Thailand's COVID-19 pandemic lockdown. Read More

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January 2021

The strategy for controlling COVID-19 in Kurdistan Regional Government (KRG)/Iraq: Identification, epidemiology, transmission, treatment, and recovery.

Int J Surg Open 2020 30;25:41-46. Epub 2020 Jun 30.

Department of Medical Laboratory Science, College of Medicals and Applied Science, Charmoo University, Kurdistan Regional Government, Chamchamal, Sulaymaniyah, 46023, Iraq.

This study has carried out a mini-review on first wave of COVID-19 infection and its control by the Kurdistan Regional Government (KRG)/Iraq. COVID-19 infection, which was named by the International Committee of Taxonomy of Viruses (ICTV) as SARS-CoV-2, is a newly identified coronavirus. The last century has seen the outbreak of numerous life-threatening human pathogens including Nipah, Ebola, Zika, Chikungunya, Middle East respiratory syndrome coronavirus (MERS-CoV), severe acute respiratory syndrome coronavirus (SARS-CoV), and more recently a novel coronavirus has been observed. Read More

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Fibromyalgia in Health Care Worker During COVID-19 Outbreak in Saudi Arabia.

Front Public Health 2021 10;9:693159. Epub 2021 Sep 10.

Department of Internal Medicine, Rheumatology Section, Qatif Central Hospital, Al Qatif, Saudi Arabia.

In the face of the contemporary COVID-19 pandemic, health service providers have emerged as the most at-risk individuals who are likely to contract the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). To measure the prevalence of fibromyalgia (FM) during COVID outbreak among health workers in Saudi Arabia using FiRST and LFESSQ tool. The study employed a cross-sectional methodology to explore the prevalence of Fibromyalgia among health workers at different health care settings in Saudi Arabia. Read More

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September 2021

Operationalizing Cooperative Research for Infectious Disease Surveillance: Lessons Learned and Ways Forward.

Front Public Health 2021 10;9:659695. Epub 2021 Sep 10.

Jacobs School of Medicine and Biomedical Sciences, Buffalo, NY, United States.

The current COVID-19 pandemic demonstrates the need for urgent and on-demand solutions to provide diagnostics, treatment and preventative measures for infectious disease outbreaks. Once solutions are developed, meeting capacities depends on the ability to mitigate technical, logistical and production issues. While it is difficult to predict the next outbreak, augmenting investments in preparedness, such as infectious disease surveillance, is far more effective than mustering last-minute response funds. Read More

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September 2021

Challenges and Controversies in COVID-19: Masking the General Population may Attenuate This Pandemic's Outbreak.

Björn Johansson

Front Public Health 2021 8;9:643991. Epub 2021 Sep 8.

Theme Aging, Karolinska University Hospital, Stockholm, Sweden.

SARS-CoV-2, the virus that causes COVID-19, spreads i. a., by respiratory droplets. Read More

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September 2021

Socio-Economic Factors Affecting the Regional Spread and Outbreak of COVID-19 in China.

Iran J Public Health 2021 Jul;50(7):1324-1333

Department of Public Health and Community Medicine, Tufts University School of Medicine, Massachusetts Boston, United States of America.

Background: This study investigated the impact of socio-economic factors on the spread and outbreak of COVID-19 based on Chinese data.

Methods: Cumulative confirmed cases were collected and divided into the First-stage cases cluster dominated by imported cases, and the Second-stage cases cluster dominated by secondary cases, according to the time of emergency state and Wuhan city lockdown. The linear regression was used for data analysis. Read More

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Flashback and lessons learnt from history of pandemics before COVID-19.

J Family Med Prim Care 2021 Jul 30;10(7):2441-2449. Epub 2021 Jul 30.

Department of Pharmacology, AIIMS, Jodhpur, Rajasthan, India.

With an increasing frequency of infectious disease outbreaks, the COVID-19 pandemic causing mortality around the world and the threat of similar future events looming large, mankind is faced with the herculean task of counteracting such threats with the best possible strategies and public health decisions. It is key that such decisions should be guided by previous examples of similar health emergencies. Here we review some of the significant infectious disease outbreaks, including epidemics and pandemics occurring worldwide in the past including their impact at population and global levels, unique challenges presented by each and the measures taken by authorities worldwide as well as the crucial lessons each epidemic or pandemic provided. Read More

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Traditional and Complementary Medicine use and beliefs during COVID-19 outbreak: A cross-sectional survey among the general population in Turkey.

Adv Integr Med 2021 Sep 20. Epub 2021 Sep 20.

Department of Microbiology, Faculty of Chemical and Life Sciences, Abdul Wali Khan University Mardan (AWKUM), Mardan, KPK, Pakistan.

Objective: Coronavirus disease 2019 (COVID-19) caused a universal psychosocial impact and individuals exposed to threats prefer to try self-care interventions and adhere to non-conventional approaches such as (T&CM) for preventive purposes. This study was conducted to determine the use and belief about T&CM among the general population during the COVID-19 outbreak.

Method: A cross-sectional online survey was carried out among the general population (aged ≥ 18 years) of Adana, Turkey during the strict lockdown period (April 11 to April 30, 2020). Read More

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September 2021

Factors that enhance or impede compliance of the public with governmental regulation of lockdown during COVID-19 in Israel.

Int J Disaster Risk Reduct 2021 Dec 22;66:102596. Epub 2021 Sep 22.

Department of Emergency Management and Disaster Medicine, School of Public Health, Sackler Faculty of Medicine, Tel Aviv University, P.O. Box 39040, Tel Aviv, 6139001, Israel.

Introduction: In the ongoing COVID-19 global pandemic, compliance to governmental orders is a challenge in the effort to contain the spread of the virus. A cross-sectional study of the Israeli population during the first wave of the outbreak is utilized to elucidate factors that enhance or impede public compliance to the governmental regulation of lockdown and illustrate the practical complexities of staying at home for an elongated time duration.

Methods: A structured questionnaire was utilized to investigate compliance with home isolation, factors that enhance and impede compliance, activities engaged during lockdown, personal resilience, and level of individual distress during the first wave of COVID-19 in Israel. Read More

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December 2021

Detection of spreader nodes in human-SARS-CoV protein-protein interaction network.

PeerJ 2021 6;9:e12117. Epub 2021 Sep 6.

Computer Science and Engineering, Jadavpur University, Kolkata, West Bengal, India.

The entire world is witnessing the coronavirus pandemic (COVID-19), caused by a novel coronavirus (n-CoV) generally distinguished as Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). SARS-CoV-2 promotes fatal chronic respiratory disease followed by multiple organ failure, ultimately putting an end to human life. International Committee on Taxonomy of Viruses (ICTV) has reached a consensus that SARS-CoV-2 is highly genetically similar (up to 89%) to the Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV), which had an outbreak in 2003. Read More

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September 2021

Polyphenols as Alternative Treatments of COVID-19.

Comput Struct Biotechnol J 2021 Sep 20. Epub 2021 Sep 20.

School of Electrical and Computer Engineering, College of Engineering, University of Georgia, Athens, 30602, GA, USA.

Although scientists around the world have put lots of effort into the development of new treatments for COVID-19 since the outbreak, no drugs except Veklury (remdesivir) have been approved by FDA. There is an urgent need to discover some alternative antiviral treatment for COVID-19. Because polyphenols have been shown to possess antiviral activities, here we conducted a large-scale virtual screening for more than 400 polyphenols. Read More

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September 2021

Comparison of first and second waves of COVID-19 through severity markers in ICU patients of a developing country.

J Community Hosp Intern Med Perspect 2021 20;11(5):576-584. Epub 2021 Sep 20.

Department of Pulmonary Medicine, Corpus Christi Medical Center, Internal Medicine, University of North Texas, Dallas, USA.

Many countries are experiencing outbreaks of the second wave of COVID-19 infection. With these outbreaks, the severity of the disease is still ambiguously projected. Certain inflammatory markers are known to be associated with the severity of the disease and regular monitoring of these biomarkers in intensive care unit admissions is paramount to improve clinical outcomes. Read More

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September 2021

Therapeutic prospects of mesenchymal stem/stromal cells in COVID-19 associated pulmonary diseases: From bench to bedside.

World J Stem Cells 2021 Aug;13(8):1058-1071

State Key Laboratory of Experimental Hematology & National Clinical Research Center for Blood Disease, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin 300020, China.

The ongoing outbreak of coronavirus disease 2019 (COVID-19) caused by the novel severe acute respiratory syndrome coronavirus 2 has become a sudden public emergency of international concern and seriously threatens millions of people's life health. Two current studies have indicated a favorable role for mesenchymal stem/stromal cells (MSCs) in clinical remission of COVID-19 associated pulmonary diseases, yet the systematical elaboration of the therapeutics and underlying mechanism is far from satisfaction. In the present review, we summarize the therapeutic potential of MSCs in COVID-19 associated pulmonary diseases such as pneumonia induced acute lung injury, acute respiratory distress syndrome, and pulmonary fibrosis. Read More

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Prediction of COVID-19 pervasiveness in six major affected states of India and two-stage variation with temperature.

Air Qual Atmos Health 2021 Sep 21:1-12. Epub 2021 Sep 21.

Department of Mathematics, Lovely Professional University, Punjab, 144411 India.

Coronavirus disease knocked in Wuhan city of China in December 2019 which spread quickly across the world and infected millions of people within a short span of time. COVID-19 is a fast-spreading contagious disease which is caused by SARS-CoV-2 (severe acute respiratory syndrome-coronavirus-2). Accurate time series forecasting modeling is the need of the hour to monitor and control the universality of COVID-19 effectively, which will help to take preventive measures to break the ongoing chain of infection. Read More

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September 2021

COVID-19 Impact on Modern Virtual Pathology Education: Challenges and Opportunities.

Iran J Pathol 2021 6;16(4):439-443. Epub 2021 Jul 6.

Department of Medical Education, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Background & Objective: Pathology education conventional methods have been disrupted by the Corona-Virus Disease 2019 (COVID-19) outbreak, compelling a re-evaluation of the means of educational interactions from the undergraduate to the postgraduate level. This commentary explores how the COVID-19 outbreak has challenged pathology education.

Methods: We reviewed the current challenges and determined the potential implications of virtual technologies on modern pathology education for the future of pathology competency learning and assessment. Read More

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Persistent High Percentage of HLA-DRCD38 CD8 T Cells Associated With Immune Disorder and Disease Severity of COVID-19.

Front Immunol 2021 9;12:735125. Epub 2021 Sep 9.

Beijing Key Laboratory of Emerging Infectious Diseases, Institute of Infectious Diseases, Beijing Ditan Hospital, Capital Medical University, Beijing, China.

Background: The global outbreak of coronavirus disease 2019 (COVID-19) has turned into a worldwide public health crisis and caused more than 100,000,000 severe cases. Progressive lymphopenia, especially in T cells, was a prominent clinical feature of severe COVID-19. Activated HLA-DRCD38 CD8 T cells were enriched over a prolonged period from the lymphopenia patients who died from Ebola and influenza infection and in severe patients infected with SARS-CoV-2. Read More

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September 2021