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Mixed-methods economic evaluation of the implementation of tobacco treatment programs in National Cancer Institute-designated cancer centers.

Implement Sci Commun 2021 Apr 9;2(1):41. Epub 2021 Apr 9.

University of Wisconsin Carbone Cancer Center, Madison, WI, USA.

Background: The Cancer Center Cessation Initiative (C3I) was launched in 2017 as a part of the NCI Cancer Moonshot program to assist NCI-designated cancer centers in developing tobacco treatment programs for oncology patients. Participating centers have implemented varied evidence-based programs that fit their institutional resources and needs, offering a wide range of services including in-person and telephone-based counseling, point of care, interactive voice response systems, referral to the quitline, text- and web-based services, and medications.

Methods: We used a mixed methods comparative case study design to evaluate system-level implementation costs across 15 C3I-funded cancer centers that reported for at least one 6-month period between July 2018 and June 2020. Read More

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Comparison of HIV-Positive Incidence Among Transgender Women and Men Who Have Sex with Men at Stand-Alone and Mobile Voluntary Counseling and Testing Facilities in Chiang Mai Province, Thailand.

AIDS Patient Care STDS 2021 Apr;35(4):116-125

Department of Statistics, Faculty of Science, Chiang Mai University, Chiang Mai, Thailand.

Human immunodeficiency virus (HIV) infection is still a major cause of death in Thais and new cases of infection are still emerging among the key population comprising men who have sex with men (MSM), sex workers and their clients, and transgender women (TGW) and people who inject drugs. The objective of this study was to compare the incidence of HIV infection between MSM and TGW who were tested at stand-alone and mobile HIV voluntary counseling and testing (VCT) centers and to identify factors associated with HIV-positive individuals from the two services. We conducted an observational study using MSM and TGW individuals with unknown HIV status from the databases at a stand-alone center and a mobile VCT belonging to the MPlus in Chiang Mai province, Thailand. Read More

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Supportive Care: Low Cost, High Value.

Am Soc Clin Oncol Educ Book 2021 Mar;41:1-11

Division of Medical Oncology, The Ohio State University, Columbus, OH.

Supportive care aims to prevent and manage adverse effects of cancer and its treatment across the entire disease continuum. Research and clinical experience in dedicated centers have demonstrated that early appropriate supportive care interventions improve symptoms, quality of life, and overall survival in a cost-effective manner. The challenge is to assess symptoms and needs with validated tools regularly and, ideally, between clinic appointments; electronic patient-reported outcome measures and dedicated easily accessible supportive care units can help. Read More

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The Changing Trends in Prenatal Diagnosis of Hemoglobinopathies in India: The Quest of a Single Center to Reduce the Burden of Disease over Three Decades.

Hemoglobin 2021 Apr 8:1-13. Epub 2021 Apr 8.

Department of Haematogenetics, Indian Council of Medical Research, National Institute of Immunohaematology, Mumbai, India.

The β-thalassemias and sickle cell disorders pose a considerable health burden in India. Of the more than 10,000 annual births of children with a severe hemoglobinopathy, only around 10.0% are managed optimally. Read More

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Audit of sweat chloride testing reveals analytical errors.

Clin Chem Lab Med 2021 Apr 7. Epub 2021 Apr 7.

Institute of Human Genetics, University of Leipzig Medical Center, Leipzig, Germany.

Objectives: Sweat chloride testing (SCT) is the mainstay for the diagnosis of cystic fibrosis (CF) and biomarker in the evaluation of CFTR-modifying drugs. To be a reliable and valid tool, analytical variance (CVA) must be minimized. However, external quality assessments have revealed significant deviations in routine clinical practice. Read More

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Disparities in accessibility to evidence-based breast cancer care facilities by rural and urban areas in Bavaria, Germany.

Cancer 2021 Apr 7. Epub 2021 Apr 7.

Institute of Clinical Epidemiology and Biometry, University of Würzburg, Würzburg, Germany.

Background: Breast cancer (BC), which is most common in elderly women, requires a multidisciplinary and continuous approach to care. With demographic changes, the number of patients with chronic diseases such as BC will increase. This trend will especially hit rural areas, where the majority of the elderly live, in terms of comprehensive health care. Read More

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Dietary supplement use in ambulatory cancer patients: a survey on prevalence, motivation and attitudes.

J Cancer Res Clin Oncol 2021 Apr 6. Epub 2021 Apr 6.

Department of Geriatrics, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Reinickendorfer Str. 61, 13347, Berlin, Germany.

Purpose: Patients with cancer often believe dietary supplements (DS) such as micronutrients and botanical products to be health supporting and non-toxic despite growing concerns regarding potential pharmacological interactions. Studies on the prevalence of DS use among patients with cancer are heterogeneous and mainly conducted at university-based cancer centers. This survey focused on a particular cancer patient group treated in an ambulatory setting without regular access to professional nutritional counselling. Read More

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Non-opioid recreational drug use and a prolonged HIV outbreak among men who have sex with men in Taiwan: An incident case-control study, 2006-2015.

J Formos Med Assoc 2021 Apr 3. Epub 2021 Apr 3.

Department of Internal Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan.

Background/purpose: Limited data are available on the role of illicit non-injecting drug use in a prolonged HIV outbreak that predominantly affected men who have sex with men (MSM) in Taiwan since 2006. We aimed to assess associations between specific types of drug use and incident HIV infections in this outbreak.

Methods: We conducted a retrospective case-control study among MSM clients at voluntary counselling and testing (VCT) service at National Taiwan University Hospital (Taipei, Taiwan). Read More

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Association of Inadvertent 9-Valent Human Papillomavirus Vaccine in Pregnancy With Spontaneous Abortion and Adverse Birth Outcomes.

JAMA Netw Open 2021 Apr 1;4(4):e214340. Epub 2021 Apr 1.

Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, New Haven, Connecticut.

Importance: The 9-valent human papillomavirus (9vHPV) vaccine is recommended for individuals through age 26 years and may be administered to women up to age 45 years. Data on 9vHPV vaccine exposures during pregnancy are limited.

Objective: To evaluate the associations between 9vHPV vaccine exposures during pregnancy or peripregnancy and selected pregnancy and birth outcomes (spontaneous abortion [SAB], preterm birth, small-for-gestational age [SGA] birth, and major structural birth defect). Read More

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Assessment of clinical and behavioral profile of clients attending integrated counseling and testing centers of a tertiary care institute in Eastern India: A secondary data analysis.

Indian J Sex Transm Dis AIDS 2020 Jul-Dec;41(2):149-155. Epub 2020 Nov 11.

Department of Community and Family Medicine, AIIMS, Bhubaneswar, Odisha, India.

Introduction: Integrated counseling and testing center (ICTC) forms the major forum under the National AIDS Control Organization (NACO) for counseling and testing of HIV-suspected patients. ICTC setup in a tertiary care institute also provides a chance for opportunistic screening of large number of individuals.

Aims: The study was done to assess and to profile the ICTC clients with respect to their seropositivity rate, their biological and behavioral risk factors, and seroconcordance rate. Read More

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November 2020

Intimate Partner Violence Experienced by Adults With Diagnosed HIV in the U.S.

Am J Prev Med 2021 Mar 11. Epub 2021 Mar 11.

Division of HIV/AIDS Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia.

Introduction: Intimate partner violence is associated with adverse health consequences among people with diagnosed HIV, which could have implications for disease progression and transmission. However, nationally representative estimates of intimate partner violence among people with diagnosed HIV are lacking. Investigators used nationally representative data to estimate the prevalence of physical violence by an intimate partner among adults with diagnosed HIV and examine the differences by selected characteristics. Read More

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Perspectives of Multidisciplinary Professional Teams during Assessment Processes for ATD Selection in the Japanese Public Provision System.

Int J Environ Res Public Health 2021 Mar 8;18(5). Epub 2021 Mar 8.

Department of Occupational Therapy, Faculty of Health Sciences, Kyorin University, 5-4-1 Shimorenjaku, Mitaka-shi, Tokyo 181-8612, Japan.

Selection of assistive technology devices (ATDs), which are imperative for persons with disabilities to improve their quality of life, requires collaboration of users and multidisciplinary professionals. However, it is still unknown how to design and implement an adequate collaborative work flow and a professional team. Under Japanese governmental ATD provision system, based on the application by clients, ATDs are mainly selected through collaborative processes with the clients and health professionals in public organizations, rehabilitation counseling centers (RCCs). Read More

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The genetic counseling profession in Austria: Stakeholders' perspectives.

J Genet Couns 2021 Apr 2. Epub 2021 Apr 2.

Institute of Human Genetics, Medical University of Innsbruck, Austria.

In contrast to most European countries, genetic counseling in Austria, Germany, and German-speaking Switzerland is exclusively carried out by medical doctors. In this study, we investigate the perspectives of key clinician stakeholders in Austrian genetics services regarding prerequisites, opportunities, and challenges of implementing master's trained genetic counselors. Semi-structured interviews with open-ended questions and thematic analysis were carried out with nine participants, mostly medical geneticists at different hierarchy levels from three Centers for Medical Genetics in Austria. Read More

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Exploring satisfaction level among outpatients regarding pharmacy facilities and services in the Kingdom of Saudi Arabia; a large regional analysis.

PLoS One 2021 1;16(4):e0247912. Epub 2021 Apr 1.

Department of Pharmaceutical Sciences, College of pharmacy, Princess Nourah Bint Abdualrahman University, Riyadh, Saudi Arabia.

Background: Evaluation of patients`satisfaction towards pharmacy services is of utmost importance to ensure the quality of care. It helps in identifying domains requiring improvements to provide high quality pharmacy services to ensure the provision of enhanced pharmaceutical care. The current study aims to ascertain the extent of satisfaction towards pharmacy services among patients attending outpatient pharmacies in Kingdom of Saudi Arabia. Read More

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Text Messaging Intervention for Young Smokers Experiencing Homelessness: Lessons Learned From a Randomized Controlled Trial.

JMIR Mhealth Uhealth 2021 04 1;9(4):e23989. Epub 2021 Apr 1.

RAND Corporation, Santa Monica, CA, United States.

Background: Smoking rates are significantly higher among young people experiencing homelessness than in the general population. Despite a willingness to quit, homeless youth have little success in doing so on their own, and existing cessation resources tailored to this population are lacking. Homeless youth generally enjoy the camaraderie and peer support that group-based programs offer, but continuous in-person support during a quit attempt can be prohibitively expensive. Read More

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Low Prognosis by the POSEIDON Criteria in Women Undergoing Assisted Reproductive Technology: A Multicenter and Multinational Prevalence Study of Over 13,000 Patients.

Front Endocrinol (Lausanne) 2021 12;12:630550. Epub 2021 Mar 12.

Department of Obstetrics and Gynecology, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, Vietnam.

Objective: To estimate the prevalence of low-prognosis patients according to the POSEIDON criteria using real-world data.

Design: Multicenter population-based cohort study.

Settings: Fertility clinics in Brazil, Turkey, and Vietnam. Read More

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Cost-effectiveness of Treatments for Opioid Use Disorder.

JAMA Psychiatry 2021 Mar 31. Epub 2021 Mar 31.

Center for Innovation to Implementation, US Department of Veterans Affairs, VA Palo Alto Health Care System, Palo Alto, California.

Importance: Opioid use disorder (OUD) is a significant cause of morbidity and mortality in the US, yet many individuals with OUD do not receive treatment.

Objective: To assess the cost-effectiveness of OUD treatments and association of these treatments with outcomes in the US.

Design And Setting: This model-based cost-effectiveness analysis included a US population with OUD. Read More

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Truth and Transparency in Crisis Pregnancy Centers.

Womens Health Rep (New Rochelle) 2020 27;1(1):224-226. Epub 2020 Jul 27.

Department of Obstetrics and Gynecology, Indiana University School of Medicine, Indianapolis, Indiana, USA.

The prevalence of crisis pregnancy centers (CPCs), their false claims, and the real harm they cause necessitate public education about their unethical practices. Also called "pregnancy resource centers" and "pregnancy support centers," CPCs are nonmedical institutions designed to deceive women seeking comprehensive pregnancy care, as their volunteers are instructed to pedal misinformation about reproductive health care. Read More

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Long-term outcomes of lifestyle intervention to prevent type 2 diabetes in people at high risk in primary health care.

Prim Care Diabetes 2021 Mar 23. Epub 2021 Mar 23.

Department of Endocrinology and Clinical Nutrition, Kuopio University Hospital, Kuopio, Finland.

Aims: The Finnish National Diabetes Prevention Program (FIN-D2D) was the first large-scale diabetes prevention program in a primary health care setting in the world. The risk reduction of type 2 diabetes was 69% after one-year intervention in high-risk individuals who were able to lose 5% of their weight. We investigated long-term effects of one-year weight change on the incidence of type 2 diabetes, cardiovascular events, and all-cause mortality. Read More

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Physical, Mental and Sexual Health Among Transgender Women. A comparative Study Among Operated Transgender and Cisgender Women in a National Tertiary Referral Network.

J Sex Med 2021 Mar 23. Epub 2021 Mar 23.

Urology Clinic, Department of Medical, Surgical and Health Science, University of Trieste, Trieste, Italy.

Background: Few studies have investigated how physical, mental and sexual function are associated with each other in operated transgender women (oTW).

Aim: To provide information on the physical, mental and sexual health of oTW in comparison with a group of cisgender women (cisW).

Methods: An age-matched control study was carried out, recruiting 125 oTW in 7 national referral centers and 80 volunteer women. Read More

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Psychotherapy racial/ethnic disparities in treatment outcomes: The role of university racial/ethnic composition.

J Couns Psychol 2021 Mar 25. Epub 2021 Mar 25.

Department of Psychology.

Objective: Mental health disparities between racial/ethnic minorities (REM) and White individuals are well documented. These disparities extend into psychotherapy and have been observed among clients receiving care at university/college counseling centers. However, less is known about if campus RE composition affects outcomes from psychotherapy for REM and White clients. Read More

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Psychosocial counseling of patients planned for hematopoietic stem-cell transplantation for malignant conditions-practical challenges and solutions from India.

Indian J Cancer 2021 Jan-Mar;58(1):122-128

Department of Medical Oncology, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Puducherry, India.

Hematopoietic stem-cell transplantation (HSCT) is a life-saving procedure often performed to cure relapsed and difficult-to-treat malignancies. Only a handful of centers in India were initially involved in the delivery of these services. However, in the last decade, more than 100 centers in the private and public domain have started offering transplant services in the country. Read More

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Body image in children with gender incongruence.

Clin Child Psychol Psychiatry 2021 Mar 24:13591045211000797. Epub 2021 Mar 24.

Center of Expertise on Gender Dysphoria, Amsterdam UMC, location VUmc, Amsterdam, The Netherlands.

Background: In the DSM-5 diagnosis of childhood Gender Dysphoria, two of the eight criteria focus on body satisfaction of the child. Nevertheless, this subject is understudied. This study aims to describe the body image of children with gender incongruence (GI) in relation to birth assigned sex and the intensity of GI. Read More

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Frequency of Contralateral Prophylactic Mastectomy in Breast Cancer Patients with a Negative BRCA1 and BRCA2 Rapid Genetic Test Result.

Ann Surg Oncol 2021 Mar 24. Epub 2021 Mar 24.

Women's College Research Institute, Women's College Hospital, Toronto, ON, Canada.

Background: There is an increasing desire for contralateral prophylactic mastectomy (CPM) among patients with unilateral breast cancer. It is unknown if risk assessment and genetic testing at the time of diagnosis will aid women in their surgical choice. We report on the uptake and predictors of CPM in women receiving a negative genetic test result for BRCA1 and BRCA2 mutations before surgery. Read More

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Challenges of and Solutions for Developing Tailored Video Interventions That Integrate Multiple Digital Assets to Promote Engagement and Improve Health Outcomes: Tutorial.

JMIR Mhealth Uhealth 2021 Mar 23;9(3):e21128. Epub 2021 Mar 23.

Translational Health Sciences Division, Research Triangle International, Seattle, WA, United States.

Background: Video is a versatile and popular medium for digital health interventions. As mobile device and app technology advances, it is likely that video-based interventions will become increasingly common. Although clinic waiting rooms are complex and busy environments, they offer the opportunity to facilitate engagement with video-based digital interventions as patients wait to see their providers. Read More

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Psychosocial counseling of patients planned for hematopoietic stem-cell transplantation for malignant conditions-practical challenges and solutions from India.

Indian J Cancer 2021 Jan 27. Epub 2021 Jan 27.

Department of Medical Oncology, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Puducherry, India.

Hematopoietic stem-cell transplantation (HSCT) is a life-saving procedure often performed to cure relapsed and difficult-to-treat malignancies. Only a handful of centers in India were initially involved in the delivery of these services. However, in the last decade, more than 100 centers in the private and public domain have started offering transplant services in the country. Read More

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January 2021

Level of implementation of WHO COVID-19 document on rights, roles and responsibilities of health care workers in a tertiary hospital in Southwest Nigeria.

Pan Afr Med J 2020 29;37(Suppl 1):52. Epub 2020 Dec 29.

Department of Internal Medicine, University of Medical Sciences Teaching Hospital Complex, Ondo City, Ondo State, Nigeria.

Introduction: in order to curb the increasing spread of COVID-19 amongst health care workers (HCWs), the World Health Organization (WHO) released the COVID-19 Rights, Roles and Responsibilities of Health workers (COVID-19 RRRHW) policy document aimed at protecting HCWs amidst the on-going pandemic. This study determined the level of implementation of the document in a tertiary hospital in Southwest Nigeria.

Methods: this was a cross-sectional descriptive study among HCWs in a tertiary hospital in South-western Nigeria that assessed the level of implementation of the WHO COVID-19 RRRHW document using a closed ended structured questionnaire. Read More

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Distinguishing the need for crisis mental health services among college students.

Psychol Serv 2021 Mar 18. Epub 2021 Mar 18.

Student Counseling Center.

The increasing frequency of college students' use of crisis mental health services at college counseling centers is exacerbating the existing challenges college counseling centers face to meet students' growing demand for mental healthcare on campus. The purpose of the present study was to investigate whether any clinical or demographic variables distinguished between students in the clinical population who did and did not use crisis services, including crisis walk-in sessions and transport to the hospital for emergency psychiatric evaluation. Clinical and demographic data from the intake paperwork of 408 students who received services from a university counseling center over a 2-year time-period were collected and analyzed to determine whether any variables were associated with significantly higher levels of crisis service use. Read More

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