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Gray matter volume in left intraparietal sulcus predicts longitudinal gains in subtraction skill in elementary school: Running title (5 words): Gray matter volume predicts subtraction.

Neuroimage 2021 Apr 6:118021. Epub 2021 Apr 6.

Department of Psychology and Human Development, Vanderbilt University, Nashville, Tennessee, USA.

Although behavioral studies show large improvements in arithmetic skills in elementary school, we do not know how brain structure supports math gains in typically developing children. While some correlational studies have investigated the concurrent association between math performance and brain structure, such as gray matter volume (GMV), longitudinal studies are needed to infer if there is a causal relation. Although discrepancies in the literature on the relation between GMV and math performance have been attributed to the different demands on quantity vs. Read More

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A Descriptive Study Exploring Semen Quality Among Indian Cancer Patients.

J Adolesc Young Adult Oncol 2021 Apr 9. Epub 2021 Apr 9.

Department of Reproductive Medicine, Gunasheela Surgical and Maternity Hospital, Bangalore, India.

To descriptively explore semen quality among Indian men with various types of malignancies. We evaluated semen parameters of male patients referred to our hospital before commencing their cancer treatment. Four hundred sixty-one male patients who were within the age range of 15-50 years were recruited with diagnosed malignancies. Read More

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Comparison of HIV-Positive Incidence Among Transgender Women and Men Who Have Sex with Men at Stand-Alone and Mobile Voluntary Counseling and Testing Facilities in Chiang Mai Province, Thailand.

AIDS Patient Care STDS 2021 Apr;35(4):116-125

Department of Statistics, Faculty of Science, Chiang Mai University, Chiang Mai, Thailand.

Human immunodeficiency virus (HIV) infection is still a major cause of death in Thais and new cases of infection are still emerging among the key population comprising men who have sex with men (MSM), sex workers and their clients, and transgender women (TGW) and people who inject drugs. The objective of this study was to compare the incidence of HIV infection between MSM and TGW who were tested at stand-alone and mobile HIV voluntary counseling and testing (VCT) centers and to identify factors associated with HIV-positive individuals from the two services. We conducted an observational study using MSM and TGW individuals with unknown HIV status from the databases at a stand-alone center and a mobile VCT belonging to the MPlus in Chiang Mai province, Thailand. Read More

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Impact of a Genomic Test on Treatment Decision in a Predominantly African American Population With Favorable-Risk Prostate Cancer: A Randomized Trial.

J Clin Oncol 2021 Apr 9:JCO2002997. Epub 2021 Apr 9.

Department of Pathology, University of Illinois at Chicago, Chicago, IL.

Purpose: The Genomic Prostate Score (GPS), performed on biopsy tissue, predicts adverse outcome in prostate cancer (PCa) and has shown promise for improving patient selection for active surveillance (AS). However, its impact on treatment choice in high-risk populations of African Americans is largely unknown and, in general, the effect of the GPS on this difficult decision has not been evaluated in randomized trials.

Methods: Two hundred men with National Comprehensive Cancer Network very low to low-intermediate PCa from three Chicago hospitals (70% Black, 16% college graduates) were randomly assigned at diagnosis to standard counseling with or without a 12-gene GPS assay. Read More

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Coping strategies in active and inactive men with prostate cancer: a qualitative study.

J Cancer Surviv 2021 Apr 9. Epub 2021 Apr 9.

Faculty of Kinesiology, University of Calgary, Calgary, Canada.

Purpose: Prostate cancer can result in a shift in the way men perceive their masculinity. Despite the interest in exercise as a treatment strategy to address masculinity concerns, there is insufficient information about how perceptions may differ in active and inactive men. The aim of this study was to explore how exercise might influence self-perceptions of masculinity in men across the exercise continuum (from active to inactive) and in men receiving different forms of treatment for their prostate cancer, including androgen deprivation therapy. Read More

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Teaching Medical Students to Help Patients Manage Their Weight: Outcomes of an Eight-School Randomized Controlled Trial.

J Gen Intern Med 2021 Apr 9. Epub 2021 Apr 9.

Department of Social and Behavioral Sciences, Harvard School of Public Health, Cambridge, MA, USA.

Background: Given the rising rates of obesity there is a pressing need for medical schools to better prepare students for intervening with patients who have overweight or obesity and for prevention efforts.

Objective: To assess the effect of a multi-modal weight management curriculum on counseling skills for health behavior change.

Design: A pair-matched, group-randomized controlled trial (2015-2020) included students enrolled in eight U. Read More

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Couples' co-regulation dynamics as a function of perceived partner dyadic coping.

Anxiety Stress Coping 2021 Apr 9:1-15. Epub 2021 Apr 9.

School of Social and Behavioral Sciences, Arizona State University, Glendale, AZ, USA.

Background And Objectives: Perceptions of partners' dyadic coping (DC) behaviors are associated with lower stress and higher relationship well-being. Albeit well-documented, these associations have predominately relied on cross-sectional data, overlooking temporal associations during conversations of mutual stress. Based on the systemic transactional model of DC [Bodenmann, G. Read More

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Professional quality of life and perceptions of spirituality and spiritual care among nurses: Relationship and affecting factors.

Perspect Psychiatr Care 2021 Apr 8. Epub 2021 Apr 8.

Department of Nursing Education, Faculty of Health Sciences, Izmir Katip Celebi University, Izmir, Turkey.

Purpose: This study aims to determine the relationship of nurses' perception of spirituality and spiritual care to the dimensions of professional quality of life, namely, nurses' compassion fatigue, burnout and compassion satisfaction, and identify the influencing factors, respectively.

Design And Methods: The population consisted of 316 nurses (response rate: 91.32%) working in various clinics of a Training and Research Hospital (gynecology, pediatrics, surgery, internal medicine and emergency service) between December 2018 and May 2019. Read More

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[Analysis of FMR1 gene CGG repeats among patients with diminished ovarian reserve].

Zhonghua Yi Xue Yi Chuan Xue Za Zhi 2021 Apr;38(4):343-346

Institute of Reproductive and Stem Cell Engineering, School of Basic Medical Science, Central South University, Changsha, Hunan 410078, China.

Objective: To explore the correlation between Fragile X mental retardation gene-1 (FMR1) gene CGG repeats with diminished ovarian reserve (DOR).

Methods: For 214 females diagnosed with DOR, DNA was extracted from peripheral blood samples. FMR1 gene CGG repeats were determined by PCR and capillary electrophoresis. Read More

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[Impact of confined placental mosaicism on non-invasive prenatal testing and pregnancy outcomes].

Zhonghua Yi Xue Yi Chuan Xue Za Zhi 2021 Apr;38(4):335-338

Fujian Provincial Key Laboratory for Prenatal Diagnosis and Birth Defect, Fujian Provincial Maternity and Child Health Cave Hospital, the Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian 350001, China.

Objective: To assess the impact of confined placental mosaicism (CPM) on non-invasive prenatal testing (NIPT) and pregnancy outcomes.

Methods: Copy number variation sequencing (CNV-seq) and single nucleotide polymorphism array (SNP-array) were carried out on placental specimen sampled from eight pregnancies with confirmed false-positive NIPT results. The impact of CPM on NIPT and pregnancy outcomes were analyzed based on the laboratory tests and clinical characteristics. Read More

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Sirt-1 Regulates Physiological Process and Exerts Protective Effects against Oxidative Stress.

Biomed Res Int 2021 23;2021:5542545. Epub 2021 Mar 23.

Department of Nuclear Medicine, General Hospital of Ningxia Medical University, Ningxia, Ningxia Hui Autonomous Region, China 750004.

Background: Recent studies suggest a correlation between the reduced Sirt-1 expression with Alzheimer's diseases (AD) and depression, respectively, suggesting a possible pathogenic role of the altered Sirt-1 expression in neuronal degenerative diseases, such as AD and depression. However, the molecular mechanisms underlying how Sirt-1 reduction impairs neuronal functions remain unknown.

Methods: We used the SK-N-SH neuroblastoma cells to study the role of Sirt-1 expression on physiological roles in neuronal cells. Read More

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Telemedicine Intervention to Improve Long-Term Risk Factor Control and Body Composition in Persons with High Cardiovascular Risk: Results from a Randomized Trial: Telehealth strategies may offer an advantage over standard institutional based interventions for improvement of cardiovascular risk in high-risk patients long-term.

Glob Heart 2021 Mar 25;16(1):21. Epub 2021 Mar 25.

Institute for Social and Preventive Medicine, University of Bern, Bern, CH.

Background: Telehealth strategies are increasingly used to support people at high cardiovascular risk long-term, but is it unclear if these interventions are effective at improving cardiovascular risk.

Objective: To evaluate the effects of a telemedicine technology-based program on risk factor control and body composition in patients at high cardiovascular risk.

Methods: This is a population based randomized controlled trial. Read More

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Psychosocial Risk Factors in Cardiac Rehabilitation: Time to Screen Beyond Anxiety and Depression.

Glob Heart 2021 Feb 19;16(1):16. Epub 2021 Feb 19.

Graduate School for Health Sciences and Institute of Social and Preventive Medicine (ISPM), University of Bern, Bern, CH.

Background: Although it is well acknowledged that psychosocial risk factors (PSRF) such as low socio-economic status, stress, social isolation, negative emotions and negative personality patterns may contribute to the development and adverse outcome of cardiovascular disease (CVD), screening for PSRF in CVD patients is usually limited to anxiety and depression, mainly for feasibility reasons. We therefore aimed to develop a user-friendly screening battery for routine assessment of PSRFs and to evaluate this instrument regarding feasibility of application, PSRF results and attendance of psychological counselling if recommended to cardiac rehabilitation (CR) patients.

Methods: This is a prospective single center cohort study including 609 consecutive CR patients. Read More

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February 2021

Linking Self-Control to Voluntary Behaviors at Workplace: The Mediating Role of Job Satisfaction.

Front Psychol 2021 23;12:530297. Epub 2021 Mar 23.

School of Economics and Management, Guangzhou Huashang College, Guangzhou, China.

Voluntary work behavior (VWB) refers to spontaneous workplace behaviors that extend beyond role norms, including extra-role behaviors that benefit the organization (i. e., organizational citizenship behavior, OCB) and negative behaviors that may harm the organization (i. Read More

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EYS mutations and implementation of minigene assay for variant classification in EYS-associated retinitis pigmentosa in northern Sweden.

Sci Rep 2021 Apr 8;11(1):7696. Epub 2021 Apr 8.

Medical Biosciences/Medical and Clinical Genetics, University of Umeå, 901 87, Umeå, Sweden.

Retinitis pigmentosa (RP) is a clinically and genetically heterogeneous group of inherited retinal degenerations. The ortholog of Drosophila eyes shut/spacemaker, EYS on chromosome 6q12 is a major genetic cause of recessive RP worldwide, with prevalence of 5 to 30%. In this study, by using targeted NGS, MLPA and Sanger sequencing we uncovered the EYS gene as one of the most common genetic cause of autosomal recessive RP in northern Sweden accounting for at least 16%. Read More

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Motivational Interviewing Enhances Group Cognitive Behavioral Therapy for Anxiety Disorders.

J Cogn Psychother 2021 Apr 8. Epub 2021 Apr 8.

School of Psychology and Counselling, Queensland University of Technology, Brisbane, Queensland, Australia.

This pilot study tested whether the addition of motivational interviewing (MI) prior to group cognitive behavioral therapy (CBT) for anxiety may improve the effectiveness of the treatment. Prior to group CBT, 40 individuals with a principal diagnosis of an anxiety disorder (40% panic disorder, 25% generalized anxiety disorder, 22.5% social phobia, and 12. Read More

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Insufficient fertility counseling and decisional regret: a call to raise our standards for fertility preservation counseling prior to gender-affirming care.

Fertil Steril 2021 Apr;115(4):901-902

Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, University of Michigan Medical School, Ann Arbor, Michigan.

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The COVID-19 pandemic and reproductive health.

Authors:
Richard S Legro

Fertil Steril 2021 Apr 6;115(4):811-812. Epub 2021 Feb 6.

Departments of Obstetrics and Gynecology and Public Health Science, Penn State College of Medicine, Hershey, Pennsylvania. Electronic address:

This introduction tees off an outstanding collection of Views and Reviews articles on the effects of the SARS-CoV-2 and COVID-19 on human reproductive health. These articles written by the experts in the field review the current literature on COVID-19 and male reproductive health, female reproductive health, and the assisted reproductive technology laboratory. Despite the prolonged nature of the pandemic and the number of people infected worldwide, there still are limited data on the effects of the virus and infection on human reproductive health and human fertility. Read More

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Contraception and Reproductive Planning for Women With Cardiovascular Disease: JACC Focus Seminar 5/5.

J Am Coll Cardiol 2021 Apr;77(14):1823-1834

Department of Medicine, Division of Cardiology, Columbia University Irving Medical Center, New York, New York, USA.

The majority of reproductive-age women with cardiovascular disease are sexually active. Early and accurate counseling by the cardiovascular team regarding disease-specific contraceptive safety and effectiveness is imperative to preventing unplanned pregnancies in this high-risk group of patients. This document, the final of a 5-part series, provides evidence-based recommendations regarding contraceptive options for women with, or at high risk for, cardiovascular disease as well as recommendations regarding pregnancy termination for women at excessive cardiovascular mortality risk due to pregnancy. Read More

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Team-Based Care of Women With Cardiovascular Disease From Pre-Conception Through Pregnancy and Postpartum: JACC Focus Seminar 1/5.

J Am Coll Cardiol 2021 Apr;77(14):1763-1777

Cardiovascular Division, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri, USA.

The specialty of cardio-obstetrics has emerged in response to the rising rates of maternal morbidity and mortality related to cardiovascular disease (CVD) during pregnancy. Women of childbearing age with or at risk for CVD should receive appropriate counseling regarding maternal and fetal risks of pregnancy, medical optimization, and contraception advice. A multidisciplinary cardio-obstetrics team should ensure appropriate monitoring during pregnancy, plan for labor and delivery, and ensure close follow-up during the postpartum period when CVD complications remain common. Read More

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[The Danish Health Authority: prevention of alcohol intake and treatment of alcohol-related disorders].

Ugeskr Laeger 2021 Apr;183(14)

Consumption of alcohol has major consequences for public health in Denmark, and many Danes still drink too much, given the health consequences. The Danish Health Authority supports the municipalities' effort with prevention of misuse of alcohol intake and treatment of alcohol-related disorders. Among other things, we monitor the prevalence of alcohol intake in the population, compose materials for counselling and financially support projects, which develop new methods for prevention and treatment in relation to alcohol. Read More

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The risk of preterm birth among women with a history of leukemia or lymphoma.

J Matern Fetal Neonatal Med 2021 Apr 8:1-9. Epub 2021 Apr 8.

Department of Epidemiology, University of Iowa, Iowa City, IA, USA.

Objective: Leukemia and lymphoma are top cancers affecting children, adolescents and young adults with high five-year survival rates. Late effects of these cancers are a concern in reproductive-age patients, including pregnancy outcomes such as preterm birth. Our study aimed to evaluate whether diagnosis of leukemia or lymphoma prior to pregnancy was associated with preterm birth (<37 weeks gestation). Read More

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Controversies in Hereditary Cancer Management.

Obstet Gynecol 2021 Apr 8. Epub 2021 Apr 8.

Division of Subspeciality Care for Women's Health-Gynecologic Oncology, Women's Health Institute, and the Breast Center, Digestive Disease and Surgery Institute, Cleveland Clinic, Cleveland, Ohio.

Personalized management of patients at risk ideally should involve a multidisciplinary team of not only genetic counselors and surgeons, but also women's health or menopause specialists, knowledgeable psychologists, and primary care providers or obstetrician-gynecologists aware of the risks and fears "previvors" (survivors of a predisposition to cancer who have not had the disease) face as well as the issues that are common postoperatively. Identification of patients at risk for hereditary cancer, understanding of current genetic testing modalities and potential results, knowledge about screening and prevention including timing of surveillance, preventive medication and risk-reducing surgeries, understanding limitations and comorbidities associated with these risk management strategies and long-term psychological support are all important in hereditary cancer management. We describe issues surrounding the identification of the high-risk patient, universal testing in breast and ovarian cancer, and testing in special populations. Read More

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Outcomes of Women Undergoing Excision of the Retained Cervix After Supracervical Hysterectomy.

Obstet Gynecol 2021 Apr 8. Epub 2021 Apr 8.

Johns Hopkins Hospital, Baltimore, Maryland; the University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania; and the Kelly Gynecologic Oncology Service, Johns Hopkins School of Medicine, Baltimore, Maryland.

Objective: To characterize the indications for and complication rates of excision of the retained cervix after supracervical hysterectomy.

Methods: We performed a retrospective cohort study of women undergoing excision of the retained cervix after supracervical hysterectomy in the 2010-2014 National Inpatient Sample. International Classification of Diseases, Ninth Revision codes were used to identify indication for the procedure and surgical complications. Read More

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Associations between weight-based teasing and disordered eating behaviors among youth.

Eat Behav 2021 Mar 29;41:101504. Epub 2021 Mar 29.

Section on Growth and Obesity, Division of Intramural Research Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), National Institutes of Health (NIH), 10 Center Drive, Bethesda, MD 20892, USA.

Weight-based teasing (WBT) is commonly reported among youth and is associated with disinhibited and disordered eating. Specifically, youth who experience WBT may engage in disordered eating behaviors to cope with the resultant negative affect. Therefore, we examined associations between WBT and disordered eating behaviors among youth and assessed whether negative affect mediated these relationships. Read More

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Exploring the mediating effect of academic engagement on math and reading achievement for students who have experienced maltreatment.

Child Abuse Negl 2021 Apr 5;117:105048. Epub 2021 Apr 5.

Department of Educational Psychology, Counseling, and Special Education, The Pennsylvania State University, United States.

Background: Students who experience maltreatment tend to underperform academically relative to their peers, requiring an understanding of academically-related mechanisms that are potential intervention targets. Academic engagement, a multidimensional construct that is influential in students' investment in learning and the school context, is one such mechanism that has been associated with positive academic outcomes and develops through interactions between students and their environment.

Objective: The purpose of this study was to examine how maltreatment experiences and trauma symptoms were indirectly associated with academic achievement in adolescence through academic engagement. Read More

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Weight-related teasing is associated with body concerns, disordered eating, and health diagnoses in racially and ethnically diverse young men.

Body Image 2021 Apr 5;38:37-48. Epub 2021 Apr 5.

Counseling Psychology and Human Services, University of Oregon, 1215 University of Oregon, Eugene, OR 97403, United States; The Prevention Science Institute, University of Oregon, 1600 Millrace Dr, Eugene, OR 97403, United States. Electronic address:

Research suggests that weight-related teasing is associated with body concerns and disordered eating in male and female adolescents and women. Yet, little is known about these associations for young men with diverse racial and ethnic identities. This study examined the association of weight-related teasing frequency and distress with body concerns, loss of control (LOC) eating, dietary restraint, and history of psychiatric and medical diagnoses in racially and ethnically diverse young men. Read More

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Exenatide Adjunct to Nicotine Patch Facilitates Smoking Cessation and May Reduce Post-Cessation Weight Gain: a Pilot Randomized Controlled Trial.

Nicotine Tob Res 2021 Apr 8. Epub 2021 Apr 8.

Center for Neurobehavioral Research on Addiction, Louis A. Faillace, M.D., Department of Psychiatry and Behavioral Sciences, UTHealth, McGovern Medical School, Houston, TX.

Introduction: Approved pharmacological treatments for smoking cessation are modestly effective, underscoring the need for improved pharmacotherapies. Glucagon-like peptide-1 receptor (GLP-1R) agonists attenuate the rewarding effects of nicotine in preclinical studies. We examined the efficacy of extended-release exenatide, a GLP-1R agonist, combined with nicotine replacement therapy (NRT, patch) for smoking cessation, craving and withdrawal symptoms, with post-cessation body weight as secondary outcome. Read More

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College students' experiences with substance use at electronic music events: A qualitative study.

J Am Coll Health 2021 Apr 8:1-9. Epub 2021 Apr 8.

Department of Special Education, Rehabilitation, and Counseling, Auburn University, Auburn, Alabama, USA.

To understand college students' experiences with substance use at electronic music events (EME), including harm-reduction strategies and receptivity to educational intervention. A purposeful sample of undergraduate students at a private Southeastern university was recruited from April 2019 to May 2019 using online advertising and in-person tabling. A qualitative, descriptive research design utilizing semistructured focus groups. Read More

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