347,543 results match your criteria cost analysis

Economic Viability and Efficacy of Day Case Versus Inpatient Tonsillectomy in Southern Iran.

Value Health Reg Issues 2021 Apr 9;24:193-198. Epub 2021 Apr 9.

Health Human Resources Research Center, School of Management and Medical Informatics, Shiraz University of Medical Sciences, Shiraz, Iran. Electronic address:

Objectives: Day case tonsillectomy compared with inpatient tonsillectomy has increasingly become a trend for many patients undergoing elective surgeries. Unjustified stays of tonsillectomy can be avoided by day case surgery, which consequently reduces treatment costs. The aim of this study was therefore to determine the cost and effectiveness of day case tonsillectomy compared with inpatient tonsillectomy. Read More

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How does the pre-treatment of landfill leachate impact the performance of O and O/UVC processes?

Chemosphere 2021 Mar 29;278:130389. Epub 2021 Mar 29.

Laboratory of Separation and Reaction Engineering-Laboratory of Catalysis and Materials (LSRE-LCM), Departamento de Engenharia Química, Faculdade de Engenharia da Universidade Do Porto, Rua Dr. Roberto Frias, 4200-465, Porto, Portugal. Electronic address:

In this study, O and O/UVC processes were evaluated for the treatment of landfill leachate after biological nitrification/denitrification, coagulation, or their combinations. The O-driven stage efficiency was assessed by the removal of color, organic matter (dissolved organic carbon (DOC) and chemical oxygen demand (COD)), and biodegradability increase (Zahn-Wellens test). Also, fluorescence excitation-emission matrix (EEM) and size exclusion chromatography coupled with OC detector (SEC-OCD) analysis were carried out for each strategy. Read More

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Effects on gait and balance of home-based active video game interventions in persons with multiple sclerosis: A systematic review.

Mult Scler Relat Disord 2021 Mar 28;51:102928. Epub 2021 Mar 28.

ILFOMER, Université de Limoges, Limoges, France; HAVAE, EA 6310, Université de Limoges, Limoges, France. Electronic address:

Background: The current coronavirus disease (COVID-19) pandemic makes it difficult to obtain physical therapy in rehabilitation centres, particularly for persons with multiple sclerosis (pwMS), who are a population at high risk, since viral infections may contribute to MS exacerbations and relapses. Active video games could be a way to maintain physical therapy at home as part of the rehabilitation. The aim of this review is to summarise the current best evidence for the effectiveness of home-based active video games on gait and balance, user compliance, feasibility and safety for pwMS. Read More

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Development of hybrid spectrofluorimetric method for simultaneous determination of Valsartan and Sacubitril in LCZ696 tablets.

Spectrochim Acta A Mol Biomol Spectrosc 2021 Mar 26;256:119748. Epub 2021 Mar 26.

Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Pharos University in Alexandria, Alexandria, Egypt.

A hybrid Spectrofluorimetric method was developed for the simultaneous determination of binary mixtures, without prior separation steps. It coupled synchronous spectrofluorimetry with derivative ratio mathematical treatment. The method was applied successfully to quantify a new model binary mixture consisting of Valsartan (VAL) and Sacubitril (SAC). Read More

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Opportunity for efficiency in clinical development: An overview of adaptive clinical trial designs and innovative machine learning tools, with examples from the cardiovascular field.

Contemp Clin Trials 2021 Apr 9:106397. Epub 2021 Apr 9.

Department of Biostatistics, University of California Los Angeles, USA.

Modern data analysis tools and statistical modeling techniques are increasingly used in clinical research to improve diagnosis, estimate disease progression and predict treatment outcomes. What seems less emphasized is the importance of the study design, which can have a serious impact on the study cost, time and the statistical efficiency. This paper provides an overview on different types of adaptive designs in clinical trials and their applications to cardiovascular trials. Read More

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Ultrasound pattern of anterolateral leg muscles in facioscapulohumeral muscular dystrophy.

Acta Neurol Scand 2021 Apr 12. Epub 2021 Apr 12.

Department of Neurology, Neuromuscular Center, University of Patras, Patras, Greece.

Background/aims Of Study: To evaluate the degree of tibialis anterior (TA) and peroneus longus (PL) muscle involvement in facioscapulohumeral muscular dystrophy (FSHD) patients using ultrasound.

Methods: We performed qualitative and quantitative assessments of muscle echogenicity, using Heckmatt's rating scale and gray scale analysis, respectively, in eight patients (five males, mean age 36.9 ± 8. Read More

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[Survival analysis of patients starting hemodialysis in Chile between 2013 and 2019].

Rev Med Chil 2020 Dec;148(12):1715-1724

Escuela de Medicina, Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile.

Background: Renal replacement therapies, especially hemodialysis (HD) in end-stage kidney disease, avoid an inevitable death caused by the disease. However, in elderly patients with multiple comorbidities, this therapy could derive in a comparable survival than conservative management. Considering that HD represents a high cost for the health system, it is worth analyzing the effects of HD on survival. Read More

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December 2020

To ban or not to ban tanning bed use for minors: A cost-effectiveness analysis from multiple US perspectives for invasive melanoma.

Cancer 2021 Apr 12. Epub 2021 Apr 12.

Department of Population Health Science and Policy, Icahn School of Medicine at Mount Sinai, New York, New York.

Background: Tanning bed use is common among US adolescents, but is associated with increased melanoma risk. The decision to ban tanning bed use by adolescents should be made in consideration of the potential health benefits and costs.

Methods: The US population aged 14 to 17 years was modeled by microsimulation, which compared ban versus no ban strategies. Read More

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Utility of preoperative labs in posterior spinal fusions for idiopathic scoliosis.

Spine Deform 2021 Apr 12. Epub 2021 Apr 12.

Department of Orthopaedic Surgery, St Louis Children's Hospital, Washington University School of Medicine, 1 Children's Place, Suite 4S60, Saint Louis, MO, 63110, USA.

Purpose: Review of 216 consecutive idiopathic scoliosis (IS) patients undergoing posterior spinal fusion (PSF) demonstrated 94.9% having abnormal lab values, but only 3.9% were referred for further evaluation. Read More

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Multidisciplinary treatment for patients with chronic kidney disease in pre-dialysis minimizes costs: a four-year retrospective cohort analysis.

J Bras Nefrol 2021 Apr 12. Epub 2021 Apr 12.

Universidade Federal de Juiz de Fora, Programa de Pós-Graduação em Saúde Brasileira, Juiz de Fora, MG, Brasil.

Introduction: Chronic kidney disease (CKD) can progress to end-stage renal disease (ESRD), and clinical studies show that this progression can be slowed. The objective of this study was to estimate the costs to Brazil's public health system (SUS) throughout the course of CKD in the pre-dialysis stage compared to the costs to the SUS of dialysis treatment (DT).

Methods: A retrospective cohort study was conducted to analyze clinical and laboratory variables; the outcome analyzed was need for DT. Read More

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Textbook Outcome: Definition and Analysis of a Novel Quality Measure in Lung Transplantation.

Ann Surg 2021 Apr 9. Epub 2021 Apr 9.

School of Medicine, Duke University, Durham, NC, USA Department of Surgery, Duke University Medical Center, Durham, NC, USA.

Objective: To define textbook outcome (TO) for lung transplantation (LTx) using a contemporary cohort from a high-volume institution.

Summary Background Data: TO is a standardized, composite quality measure based on multiple postoperative endpoints representing the ideal "textbook" hospitalization.

Methods: Adult patients who underwent LTx at our institution between 2016-2019 were included. Read More

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Analysis of COVID-19 Patients with Acute Respiratory Distress Syndrome Managed with Extracorporeal Membrane Oxygenation at us Academic Centers.

Ann Surg 2021 Apr 9. Epub 2021 Apr 9.

From the Department of Surgery, University of California, Irvine Medical Center, Orange, California From Vizient, Centers for Advanced Analytics and Informatics, Chicago, Illinois From the Department of Medicine, University of California, Irvine Medical Center, Orange, California.

Objective: This study analyzed the outcomes of COVID-19 patients with ARDS who were managed with extracorporeal membrane oxygenation (ECMO) across 155 US academic centers.

Summary Background Data: ECMO has been utilized in COVID-19 patients with acute respiratory distress syndrome (ARDS) and refractory hypoxemia. Early case series with the use of ECMO in these patients reported high mortality exceeding 90%. Read More

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Wiad Lek 2021 ;74(3 cz 2):674-677


Objective: The aim: To determine the level of patients' satisfaction with the received dental care in regional dental clinic and to make proposals for improving the quality of dental care based on the survey results.

Patients And Methods: Materials and methods: 221 copies of the questionnaires completed by the respondents; sociological method (questionnaire), medical-statistical, analysis and bibliosemantic methods were used.

Results: Results: Patients expressed high satisfaction with the quality of dental care according to the criteria of geographical accessibility (4. Read More

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January 2021

Virtual Reality Self-help Treatment for Aviophobia: Protocol for a Randomized Controlled Trial.

JMIR Res Protoc 2021 Apr 12;10(4):e22008. Epub 2021 Apr 12.

Clinical Psychology, Department of Clinical, Neuro- and Developmental Psychology, Vrije Universiteit Amsterdam, Amsterdam, Netherlands.

Background: Aviophobia (the fear of flying) can greatly impact the daily life functioning of people with the condition. Traditional exposure-based treatment is hampered by the limited availability of airplane practice situations, which is a result of economical and practical concerns. Easily accessible and low-cost virtual reality exposure therapy may address these challenges. Read More

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A method for prioritizing the modification of ergonomic and physical aspects of the workplace to enhance overall worker satisfaction in control centre buildings (CCBs).

Int J Occup Saf Ergon 2021 Apr 12:1-28. Epub 2021 Apr 12.

Department of Mechanical Engineering, University of Tehran, Iran.

This paper aims to develop a method for prioritizing indoor environmental quality parameters of the workplace (i.e. temperature, lighting, acoustic, air quality, layout, furnishing, cleanliness and maintenance) to enhance occupants' workspace satisfaction. Read More

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Medical costs of and changes in glaucoma treatment among patients newly starting glaucoma care.

Curr Eye Res 2021 Apr 11. Epub 2021 Apr 11.

Department of Ophthalmology, Faculty of Medicine, University of Yamanashi.

: To use a medical claim database to investigate medical costs and treatment patterns among patients newly starting glaucoma care.: Subjects registered in the Japan Medical Database Center (JMDC) from January 2005 to March 2016 who were newly diagnosed with glaucoma, started glaucoma treatment, and had treatment records covering more than five years were included in the analysis. All direct medical costs were collected for a period of up to ten years. Read More

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Costs and health resource use in patients with X-linked myotubular myopathy: insights from U.S. commercial claims.

J Manag Care Spec Pharm 2021 Apr 12:1-8. Epub 2021 Apr 12.

Harvard Medical School and Boston Children's Hospital, Boston, MA.

In X-linked myotubular myopathy (XLMTM), mutations in the gene result in absence or dysfunction of myotubularin, a protein required for normal development, maintenance, and function of skeletal muscle. Extreme muscle weakness results in severe respiratory failure that is fatal for approximately half of XLMTM-affected children by age 18 months. Most surviving patients require invasive mechanical ventilation, feeding tubes, and wheelchairs for mobility, due to profoundly impaired motor function. Read More

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FleXert: A Soft, Actuatable Multiwell Plate Insert for Cell Culture under Stretch.

ACS Biomater Sci Eng 2021 Apr 12. Epub 2021 Apr 12.

Bristol Robotics Laboratory, University of Bristol, T Block, Frenchay Campus, Coldharbour Lane, Bristol BS16 1QY, United Kingdom.

Porous multiwell plate inserts are widely used in biomedical research to study transport processes or to culture cells/tissues at the air-liquid interface. These inserts are made of rigid materials and used under static culture conditions, which are unrepresentative of biological microenvironments. Here, we present FleXert, a soft, actuatable cell culture insert that interfaces with six-well plates. Read More

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Introduction to Special Issue on Risk Assessment, Economic Evaluation, and Decisions.

Risk Anal 2021 Apr;41(4):559-564

Harvard T.H. Chan School of Public Health, Boston, MA, USA.

Integrating risk assessment, economic evaluation, and uncertainty to inform policy decisions is a core challenge to risk analysis. In September 2019, the Harvard Center for Risk Analysis, with support from the Society for Risk Analysis Economics and Benefits Analysis Specialty Group and others, convened a workshop to address this issue. The workshop built in part on the recommendations of the 2009 National Research Council report, Science and Decisions: Advancing Risk Assessment. Read More

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Robot-assisted radical prostatectomy versus standard laparoscopic radical prostatectomy: an evidence-based analysis of comparative outcomes.

World J Urol 2021 Apr 11. Epub 2021 Apr 11.

Division of Urology, VCU Health, Richmond, VA, 23298-0118, USA.

Purpose: To provide a systematic analysis of the comparative outcomes of robot-assisted radical prostatectomy (RARP) versus laparoscopic radical prostatectomy (LRP) in the treatment of prostate cancer based on the best currently available evidence.

Methods: An independent systematic review of the literature was performed up to February 2021, using MEDLINE, EMBASE, and Web of Science databases. Preferred reporting items for systematic review and meta-analysis (PRISMA) recommendations were followed to design search strategies, selection criteria, and evidence reports. Read More

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The Impact of COVID-19 on Primary Care General Practice Consultations in a Teaching Hospital in Shanghai, China.

Front Med (Lausanne) 2021 26;8:642496. Epub 2021 Mar 26.

Department of General Practice, Tongren Hospital, Shanghai, China.

The COVID-19 (2019 novel coronavirus disease) pandemic is deeply concerning because of its massive mortality and morbidity, creating adverse perceptions among patients likely to impact on their overall medical care. Thus, we evaluated the impact of the COVID-19 pandemic on the pattern of primary care consultations within a Shanghai health district. A retrospective observational cohort study was performed, with data analyzed concerning the pattern of patient visits to general practitioners within the Tongren Hospital network (the sole provider of general practice to the population of 700,000). Read More

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Research on the Allocation of 3D Printing Emergency Supplies in Public Health Emergencies.

Front Public Health 2021 26;9:657276. Epub 2021 Mar 26.

Business School, University of Shanghai for Science of Technology, Shanghai, China.

Significant public health emergencies greatly impact the global supply chain system of production and cause severe shortages in personal protective and medical emergency supplies. Thus, rapid manufacturing, scattered distribution, high design degrees of freedom, and the advantages of the low threshold of 3D printing can play important roles in the production of emergency supplies. In order to better realize the efficient distribution of 3D printing emergency supplies, this paper studies the relationship between supply and demand of 3D printing equipment and emergency supplies produced by 3D printing technology after public health emergencies. Read More

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Comprehensive Comparison Between Adjuvant Targeted Therapy and Chemotherapy for EGFR-Mutant NSCLC Patients: A Cost-Effectiveness Analysis.

Front Oncol 2021 25;11:619376. Epub 2021 Mar 25.

Cancer Center, The First Hospital of Jilin University, Changchun, China.

Background: Chemotherapy has been the current standard adjuvant treatment for early-stage non-small-cell lung cancer (NSCLC) patients, while recent studies showed benefits of epidermal growth factor receptor-tyrosine kinase inhibitor (EGFR-TKI). We conducted a cost-effectiveness analysis to comprehensively evaluate the benefit of EGFR-TKI compared with chemotherapy for early-stage EGFR-mutant NSCLC patients after resection from the perspective of the Chinese health care system.

Method: A Markov model was established. Read More

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Concurrent Validation and Reference Values of Gluteus Medius Clinical Test.

Int J Sports Phys Ther 2021 Apr 1;16(2):335-341. Epub 2021 Apr 1.

Head of the Physical Therapy Department, Minas Tenis Clube.

Context: The hip abductor muscles, mainly the gluteus medius, are responsible for controlling hip adduction in a closed kinetic chain. Frontal plane knee alignment, assessed during functional activities such squatting, jumping and running, may overload joint structures, like the anterior cruciate ligament and patellofemoral joint. The hand-held dynamometer is reliable and effective for testing the muscular strength of the hip abductors. Read More

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Reliability of the Cutting Alignment Scoring Tool (CAST) to Assess Trunk and Limb Alignment During a 45-Degree Side-Step Cut.

Int J Sports Phys Ther 2021 Apr 1;16(2):312-321. Epub 2021 Apr 1.

The Micheli Center for Sports Injury Prevention; Waseda University.

Background: Three-dimensional (3D) motion analysis is considered the gold standard for evaluating human movement. However, its clinical utility is limited due to cost, operating expertise, and lengthy data processing time. Numerous qualitative scoring systems have been introduced to assess trunk and lower extremity biomechanics during functional tasks. Read More

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Advances in airborne microorganisms detection using biosensors: A critical review.

Front Environ Sci Eng 2021 5;15(3):47. Epub 2021 Apr 5.

School of Mechanical Engineering and Safety Engineering, Institute of Particle Technology, University of Wuppertal, Wuppertal, D-42119 Germany.

Humanity has been facing the threat of a variety of infectious diseases. Airborne microorganisms can cause airborne infectious diseases, which spread rapidly and extensively, causing huge losses to human society on a global scale. In recent years, the detection technology for airborne microorganisms has developed rapidly; it can be roughly divided into biochemical, immune, and molecular technologies. Read More

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Simultaneous bilateral thoracoscopic lobectomy for synchronous bilateral multiple primary lung cancer-single center experience.

J Thorac Dis 2021 Mar;13(3):1717-1727

Department of Thoracic Surgery, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, China.

Background: The aim of this study was to investigate the feasibility and safety of simultaneous bilateral thoracoscopic lobectomy and compare perioperative and late outcomes between simultaneous and staged bilateral thoracoscopic lobectomy.

Methods: Between January 2013 and December 2017, the medical records of patients who underwent bilateral thoracoscopic lobectomy for synchronous bilateral multiple primary lung cancer (SPLC) were reviewed retrospectively. Univariate analysis was used to examine the factors associated with morbidity. Read More

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The cost-effectiveness of computer navigation in primary total knee replacement: a scoping review.

EFORT Open Rev 2021 Mar 1;6(3):173-180. Epub 2021 Mar 1.

University of Melbourne Department of Surgery, Fitzroy, Australia.

Despite additional costs associated with the use of computer navigation technology in total knee replacement (TKR), its impact on quality-adjusted life years following surgery has not been demonstrated. Cost-effectiveness evaluations require a balanced assessment of both quality and cost metrics.This review sought to evaluate the cost-effectiveness of computer navigation, identify barriers to translation, and suggest directions for further investigation. Read More

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Litigations in trauma and orthopaedic surgery: analysis and outcomes of medicolegal claims during the last 10 years in the United Kingdom National Health Service.

Haroon Majeed

EFORT Open Rev 2021 Mar 1;6(3):152-159. Epub 2021 Mar 1.

Manchester University Foundation NHS Trust, Manchester, UK.

This study analyses the outcomes of litigation claims in trauma and orthopaedic surgery between 2008/2009 and 2018/2019.Utilizing a formal request to the NHS Resolution under the Freedom of Information Act, the data related to claims against orthopaedic surgery were obtained. A total of 8548 claims were analysed and re-grouped to perform a meaningful analysis for the type of claims and the type of injuries. Read More

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Bariatric surgery outcomes in Medicare beneficiaries.

Obes Sci Pract 2021 Apr 22;7(2):176-191. Epub 2020 Dec 22.

Department of Surgery University of Minnesota Minneapolis Minnesota USA.

Background: The Medicare population is increasing while the prevalence of obesity remains high. Bariatric surgery is the most efficacious treatment of obesity and its comorbidities. The objective of this investigation was to assess trends in utilization, readmission, mortality, and cost of bariatric surgery in the Medicare population. Read More

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