Epilepsy Res 2021 Mar 23;173:106621. Epub 2021 Mar 23.
Department of Medical Imaging, Jinling Hospital, The First School of Clinical Medicine, Southern Medical University, Nanjing, 210002, China; Department of Medical Imaging, Jinling Hospital, Nanjing University School of Medicine, Nanjing, 210002, China; State Key Laboratory of Analytical Chemistry for Life Science, Nanjing University, Nanjing, 210093, China; Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, 149 Thirteenth Street, Suite 2301, Charlestown, MA, 02129, USA. Electronic address:
To investigate the morphological changes of cerebral cortex correlating with anti-seizure medication in Childhood Epilepsy with Centrotemporal Spikes (CECTS), and their relationships with seizure control. This study included a total of 188 children, including 62 patients with CECTS taking anti-seizure drugs, 56 patients with drug-naive, and 70 healthy controls. A portion of cases were also followed-up for longitudinal analysis. Read More