Exp Eye Res 2021 Apr 20;207:108579. Epub 2021 Apr 20.
The Institute of Optics, University of Rochester, Rochester, NY, 14627, USA; The Center for Visual Science, University of Rochester, Rochester, NY, 14627, USA; The Flaum Eye Institute, University of Rochester, Rochester, NY, 14642, USA. Electronic address:
Laser-induced refractive index change (LIRIC) is a new, non-incisional, non-ablative, femtosecond photo-modification technique being developed for vision correction in humans. Prior, exvivo studies showed intra-tissue refractive index change to induce minimal cell death, restricted to the laser focal zone in the corneal stroma, and with no observable damage to the epithelium or endothelium. Here, we used live rabbits to ascertain longer-term consequences of LIRIC in vivo. Read More