630 results match your criteria corpus consists

Cancer of the corpus uteri: 2021 update.

Int J Gynaecol Obstet 2021 Oct;155 Suppl 1:45-60

Department of Radiation Oncology, Leiden University Medical Center, Leiden, The Netherlands.

Endometrial cancer is the most common gynecological malignancy in high- and middle-income countries. Although the overall prognosis is relatively good, high-grade endometrial cancers have a tendency to recur. Recurrence needs to be prevented since the prognosis for recurrent endometrial cancer is dismal. Read More

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October 2021

DUKweb, diachronic word representations from the UK Web Archive corpus.

Sci Data 2021 Oct 15;8(1):269. Epub 2021 Oct 15.

The Alan Turing Institute, London, United Kingdom.

Lexical semantic change (detecting shifts in the meaning and usage of words) is an important task for social and cultural studies as well as for Natural Language Processing applications. Diachronic word embeddings (time-sensitive vector representations of words that preserve their meaning) have become the standard resource for this task. However, given the significant computational resources needed for their generation, very few resources exist that make diachronic word embeddings available to the scientific community. Read More

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October 2021

Digital hermeneutics: scaled readings of online depression discourses.

Med Humanit 2021 Oct 14. Epub 2021 Oct 14.

Department of Informatics, King's College London, London, London, UK

When it comes to understanding experiences of illness, humanities and social sciences research have traditionally reserved a prominent role for narrative. Yet, depression has characteristics that withstand the form of traditional narratives, such as a lack of desire and an impotence to act. How can a 'datafied' approach to online forms of depression writing pose a valuable addition to existing narrative approaches in health humanities? In this article, we analyse lay people's depression discourses online. Read More

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October 2021

Progressive macrographia for block letter writing: A case study.

Cortex 2021 Sep 24;144:56-69. Epub 2021 Sep 24.

Department of Neuroscience & Padova Neuroscience Center, University of Padova, Padova, Italy; IRCCS San Camillo Hospital, Venice, Italy. Electronic address:

"Macrographia", a relatively rare symptom generally following cerebellar diseases, consists of an abnormally large handwriting. The case reported in the present investigation shows several outstanding features. First, it is of the progressive variety, letters increase in size as one goes through the word towards the lower-right portion of space. Read More

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September 2021

LitCovid-AGAC: cellular and molecular level annotation data set based on COVID-19.

Genomics Inform 2021 Sep 30;19(3):e23. Epub 2021 Sep 30.

Hubei Key Lab of Agricultural Bioinformatics, College of Informatics, Huazhong Agricultural University, 430070 Wuhan, China.

Currently, coronavirus disease 2019 (COVID-19) literature has been increasing dramatically, and the increased text amount make it possible to perform large scale text mining and knowledge discovery. Therefore, curation of these texts becomes a crucial issue for Bio-medical Natural Language Processing (BioNLP) community, so as to retrieve the important information about the mechanism of COVID-19. PubAnnotation is an aligned annotation system which provides an efficient platform for biological curators to upload their annotations or merge other external annotations. Read More

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September 2021

Identification of the Lingual Papillae in the sugar glider (Petaurus breviceps) by scanning electron microscopy and light microscopy.

Anat Histol Embryol 2021 Sep 9. Epub 2021 Sep 9.

Department of Anatomy, Faculty of Veterinary Medicine, Universitas Gadjah Mada, Yogyakarta, Indonesia.

A morphological description of the sugar glider's (Petaurus breviceps) tongue was obtained from five individual sugar gliders and analysed under a scanning electron microscope and a light microscope using four methods of staining. The tongue has a noticeably elongated structure with three regions: apex, corpus and radix. Transition to the corpus is indicated by the sulcus medianus linguae and the frenulum on its ventral surface. Read More

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September 2021

ParaMed: a parallel corpus for English-Chinese translation in the biomedical domain.

BMC Med Inform Decis Mak 2021 09 6;21(1):258. Epub 2021 Sep 6.

Institute of Deep Learning, Baidu Research, Sunnyvale, USA.

Background: Biomedical language translation requires multi-lingual fluency as well as relevant domain knowledge. Such requirements make it challenging to train qualified translators and costly to generate high-quality translations. Machine translation represents an effective alternative, but accurate machine translation requires large amounts of in-domain data. Read More

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September 2021

The Immunohistochemical Expression of MCM-3, -5, and -7 Proteins in the Uterine Fibroids.

Curr Issues Mol Biol 2021 Jul 25;43(2):802-817. Epub 2021 Jul 25.

Division of Histology and Embryology, Department of Histology and Human Morphology, Wroclaw Medical University, 50-368 Wroclaw, Poland.

Uterine fibroids are the most common mesenchymal uterine neoplasms; their prevalence is estimated in 40%-60% of women under 35 and in 70%-80% of women over 50 years of age. The current research aims to focus on the etiopathogenesis of uterine fibroids, the factors that affect their growth, and markers with diagnostic and prognostic properties. The MCM (minichromosome maintenance) protein family consists of peptides whose primary function is participation in the molecular mechanism of creating replication forks while regulating DNA synthesis. Read More

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A Fine-Tuned Bidirectional Encoder Representations From Transformers Model for Food Named-Entity Recognition: Algorithm Development and Validation.

J Med Internet Res 2021 Aug 9;23(8):e28229. Epub 2021 Aug 9.

Computer Systems Department, Jožef Stefan Institute, Ljubljana, Slovenia.

Background: Recently, food science has been garnering a lot of attention. There are many open research questions on food interactions, as one of the main environmental factors, with other health-related entities such as diseases, treatments, and drugs. In the last 2 decades, a large amount of work has been done in natural language processing and machine learning to enable biomedical information extraction. Read More

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Extraction and Evaluation of Corpus Callosum from 2D Brain MRI Slice: A Study with Cuckoo Search Algorithm.

Comput Math Methods Med 2021 1;2021:5524637. Epub 2021 Aug 1.

Research Scholar, Anna University, Chennai, India.

The work proposes a computer-based diagnosis method (CBDM) to delineate and assess the corpus callosum (CC) segment from the 2-dimensional (2D) brain magnetic resonance images (MRI). The proposed CBDM consists of two parts: (1) preprocessing and (2) postprocessing sections. The preprocessing tools have a multithreshold technique with the chaotic cuckoo search (CCS) algorithm and a preferred threshold procedure. Read More

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Cell-type and subcellular compartment-specific APEX2 proximity labeling reveals activity-dependent nuclear proteome dynamics in the striatum.

Nat Commun 2021 08 11;12(1):4855. Epub 2021 Aug 11.

Department of Neurobiology, Northwestern University, Evanston, IL, USA.

The vertebrate brain consists of diverse neuronal types, classified by distinct anatomy and function, along with divergent transcriptomes and proteomes. Defining the cell-type specific neuroproteomes is important for understanding the development and functional organization of neural circuits. This task remains challenging in complex tissue, due to suboptimal protein isolation techniques that often result in loss of cell-type specific information and incomplete capture of subcellular compartments. Read More

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Further Characterization of Intrastriatal Lipopolysaccharide Model of Parkinson's Disease in C57BL/6 Mice.

Int J Mol Sci 2021 Jul 9;22(14). Epub 2021 Jul 9.

Health and Biomedical Innovation, Clinical and Health Sciences, University of South Australia, Adelaide 5000, Australia.

Parkinson's disease (PD) is the most common movement disorder, characterized by progressive degeneration of the nigrostriatal pathway, which consists of dopaminergic cell bodies in substantia nigra and their neuronal projections to the striatum. Moreover, PD is associated with an array of non-motor symptoms such as olfactory dysfunction, gastrointestinal dysfunction, impaired regulation of the sleep-wake cycle, anxiety, depression, and cognitive impairment. Inflammation and concomitant oxidative stress are crucial in the pathogenesis of PD. Read More

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Myelination of Callosal Axons Is Hampered by Early and Late Forelimb Amputation in Rats.

Cereb Cortex Commun 2021 27;2(1):tgaa090. Epub 2020 Nov 27.

Post-Graduate Program in Morphological Sciences, Institute of Biomedical Sciences, Federal University of Rio de Janeiro, Rio de Janeiro CEP 21941-902, Brazil.

Deafferentation is an important determinant of plastic changes in the CNS, which consists of a loss of inputs from the body periphery or from the CNS itself. Although cortical reorganization has been well documented, white matter plasticity was less explored. Our goal was to investigate microstructural interhemispheric connectivity changes in early and late amputated rats. Read More

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November 2020

ITEXT-BIO: Intelligent Term EXTraction for BIOmedical analysis.

Health Inf Sci Syst 2021 Dec 10;9(1):29. Epub 2021 Jul 10.

TETIS, Univ Montpellier, AgroParisTech, CIRAD, CNRS, INRAE, Montpellier, France.

Here, we introduce ITEXT-BIO, an intelligent process for biomedical domain terminology extraction from textual documents and subsequent analysis. The proposed methodology consists of two complementary approaches, including free and driven term extraction. The first is based on term extraction with statistical measures, while the second considers morphosyntactic variation rules to extract term variants from the corpus. Read More

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December 2021

Identification of antibiotic resistance patterns in strains isolated from gastric biopsies using real-time PCR and genotypic analysis.

Ann Gastroenterol 2021 Jul-Aug;34(4):501-509. Epub 2021 Apr 2.

Department of Medicine (John Schembri, Anthea Pisani, Eliezer Zahra Bianco, James Gauci, Martina Muscat, Pierre Ellul).

Background: is associated with dyspepsia, mucus-associated lymphoid tissue lymphoma, gastritis, and peptic ulcer disease. Treatment in Malta consists of triple therapy, which consists of a proton pump inhibitor and 2 of the antibiotics amoxicillin, clarithromycin, metronidazole and fluoroquinolones. We aimed to determine the resistance rates for clarithromycin and fluoroquinolones in patients with , and its incidence, in patients undergoing an esophagogastroduodenoscopy (EGD) using real-time polymerase chain reaction (RT-PCR). Read More

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Polyphonic training set synthesis improves self-supervised urban sound classification.

J Acoust Soc Am 2021 06;149(6):4309

École Centrale de Nantes, LS2N, F-44322 Nantes, France.

Machine listening systems for environmental acoustic monitoring face a shortage of expert annotations to be used as training data. To circumvent this issue, the emerging paradigm of self-supervised learning proposes to pre-train audio classifiers on a task whose ground truth is trivially available. Alternatively, training set synthesis consists in annotating a small corpus of acoustic events of interest, which are then automatically mixed at random to form a larger corpus of polyphonic scenes. Read More

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MicroRNA miR-8 promotes cell growth of corpus allatum and juvenile hormone biosynthesis independent of insulin/IGF signaling in Drosophila melanogaster.

Insect Biochem Mol Biol 2021 09 26;136:103611. Epub 2021 Jun 26.

Guangdong Provincial Key Laboratory of Insect Developmental Biology and Applied Technology, Institute of Insect Science and Technology & School of Life Sciences, South China Normal University, Guangzhou, 510631, China. Electronic address:

The Drosophila melanogaster corpus allatum (CA) produces and releases three types of sesquiterpenoid hormones, including juvenile hormone III bisepoxide (JHB3), juvenile hormone III (JH III), and methyl farnesoate (MF). JH biosynthesis involves multiple discrete enzymatic reactions and is subjected to a comprehensive regulatory network including microRNAs (miRNAs). Using a high throughput sequencing approach, we have identified abundant miRNAs in the D. Read More

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September 2021

Expression and distribution of neuroglobin and hypoxia-inducible factor-1α in the adult yak telencephalon.

Vet Med Sci 2021 Sep 19;7(5):1707-1717. Epub 2021 Jun 19.

College of Life Science and Technology, Gansu Agricultural University, Lanzhou City, Gansu Province, People's Republic of China.

The telencephalon is also known as the cerebrum, and it consists of the largest part of the brain. It makes up about 85% of the total weight of the brain. Neuroglobin (Ngb) is a protein found in neurons of both the peripheral and central nervous system that appears to convey some resilience to hypoxia, while the hypoxia-inducible factor (Hif-1α) is a dimeric protein complex that plays an integral role in the body's response to low oxygen concentrations, or hypoxia. Read More

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September 2021

[Update on Susac syndrome].

Rev Med Interne 2021 Jun 9. Epub 2021 Jun 9.

Service de médecine interne, Hôpital Bichat, Paris, France; Université de Paris, Paris, France. Electronic address:

Susac syndrome is a rare disease affecting mainly young women, characterized by a microangiopathy limited to the cerebral, retinal, and cochlear vessels. Although the pathophysiology of Susac syndrome is not yet fully elucidated, recent advances favour a primitive vasculitis affecting the cerebral, retinal and cochlear small vessels. Susac syndrome must be recognized in the presence of the pathognomonic clinical triad associating: 1/subacute encephalopathy with unusual headache and pseudopsychiatric features associated with diffuse white matter, grey matter nuclei and specifically corpus callosum lesions on brain MRI; 2/eye involvement that may be pauci-symptomatic, with occlusions of the branches of the central artery of the retina at fundoscopy and arterial wall hyperfluorescence on fluorescein angiography; and 3/cochleo-vestibular damage with hearing loss predominating at low frequencies on the audiogram. Read More

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The Unique Penile Morphology of the Short-Beaked Echidna, Tachyglossus aculeatus.

Sex Dev 2021 29;15(4):262-271. Epub 2021 Apr 29.

School of BioSciences, University of Melbourne, Melbourne, Victoria, Australia.

Monotremes diverged from therian mammal ancestors approximately 184 million years ago and have a number of novel reproductive characteristics. One in particular is their penile morphology. There are differences between echidna and platypus phalluses, but both are somewhat similar in structure to the reptilian phallus. Read More

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Annotation and initial evaluation of a large annotated German oncological corpus.

JAMIA Open 2021 Apr 19;4(2):ooab025. Epub 2021 Apr 19.

Knowledge Management for Bioinformatics, Humboldt Universität zu Berlin, Berlin, Germany.

Objective: We present the Berlin-Tübingen-Oncology corpus (BRONCO), a large and freely available corpus of shuffled sentences from German oncological discharge summaries annotated with diagnosis, treatments, medications, and further attributes including negation and speculation. The aim of BRONCO is to foster reproducible and openly available research on Information Extraction from German medical texts.

Materials And Methods: BRONCO consists of 200 manually deidentified discharge summaries of cancer patients. Read More

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Failure of hypothesis evaluation as a factor in delusional belief.

Cogn Neuropsychiatry 2021 07 20;26(4):213-230. Epub 2021 Apr 20.

Corpus Christi College, Oxford OX1 4JF, UK.

Introduction: In accounts of the two-factor theory of delusional belief, the second factor in this theory has been referred to only in the most general terms, as a failure in the processes of hypothesis evaluation, with no attempt to characterise those processes in any detail. Coltheart and Davies ([2021]. How unexpected observations lead to new beliefs: A Peircean pathway. Read More

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Late-life cynical hostility is associated with white matter alterations and the risk of Alzheimer's disease.

Psychol Med 2021 Apr 14:1-10. Epub 2021 Apr 14.

IGF, Univ Montpellier, CNRS, INSERM, Montpellier, France.

Background: Cynical hostility (CH), a specific dimension of hostility that consists of a mistrust of others, has been suggested as a high-risk trait for dementia. However, the influence of CH on the incidence of Alzheimer's disease (AD) remains poorly understood. This study investigated whether late-life CH is associated with AD risk and structural neuroimaging markers of AD. Read More

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NLM-Gene, a richly annotated gold standard dataset for gene entities that addresses ambiguity and multi-species gene recognition.

J Biomed Inform 2021 06 9;118:103779. Epub 2021 Apr 9.

National Library of Medicine, National Institutes of Health, Bethesda, MD, USA. Electronic address:

The automatic recognition of gene names and their corresponding database identifiers in biomedical text is an important first step for many downstream text-mining applications. While current methods for tagging gene entities have been developed for biomedical literature, their performance on species other than human is substantially lower due to the lack of annotation data. We therefore present the NLM-Gene corpus, a high-quality manually annotated corpus for genes developed at the US National Library of Medicine (NLM), covering ambiguous gene names, with an average of 29 gene mentions (10 unique identifiers) per document, and a broader representation of different species (including Homo sapiens, Mus musculus, Rattus norvegicus, Drosophila melanogaster, Arabidopsis thaliana, Danio rerio, etc. Read More

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Sponge-dwelling fauna: a review of known species from the Northwest Tropical Atlantic coral reefs.

Biodivers Data J 2021 15;9:e63372. Epub 2021 Mar 15.

Universidad Nacional Autónoma de México, Merida, Mexico Universidad Nacional Autónoma de México Merida Mexico.

Background: Within tropical shallow-water coral reefs, marine sponges provide microhabitats for a wide range of fauna. Although there have been numerous studies and reports of symbiotic relationships amongst sponges and their associated fauna, those pieces of information are isolated and disconnected. For this reason, based on the available literature, we compiled a species-interaction dataset of coral reef marine sponge-associated fauna known to date. Read More

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NLM-Chem, a new resource for chemical entity recognition in PubMed full text literature.

Sci Data 2021 03 25;8(1):91. Epub 2021 Mar 25.

National Library of Medicine, National Institutes of Health, Bethesda, MD, 20894, USA.

Automatically identifying chemical and drug names in scientific publications advances information access for this important class of entities in a variety of biomedical disciplines by enabling improved retrieval and linkage to related concepts. While current methods for tagging chemical entities were developed for the article title and abstract, their performance in the full article text is substantially lower. However, the full text frequently contains more detailed chemical information, such as the properties of chemical compounds, their biological effects and interactions with diseases, genes and other chemicals. Read More

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A multidisciplinary fetal neurosurgical service-5 years of fetal outcomes from a national referral centre.

Ir J Med Sci 2021 Feb 27. Epub 2021 Feb 27.

Fetal Medicine, National Maternity Hospital, Dublin 2, Ireland.

Background: A specialist fetal neurosurgical clinic was set up in order to improve patient care in a tertiary referral fetal medicine centre. The clinic provides a targeted clinical service for women diagnosed with fetal neurological abnormalities. The service consists of fetal MRI, fetal ultrasound and joint assessment and counselling from neurosurgery and fetal medicine teams. Read More

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February 2021

A Comprehensive Overview of the COVID-19 Literature: Machine Learning-Based Bibliometric Analysis.

J Med Internet Res 2021 03 8;23(3):e23703. Epub 2021 Mar 8.

Division of Information and Computing Technology, College of Science and Engineering, Hamad Bin Khalifa University, Qatar Foundation, Doha, Qatar.

Background: Shortly after the emergence of COVID-19, researchers rapidly mobilized to study numerous aspects of the disease such as its evolution, clinical manifestations, effects, treatments, and vaccinations. This led to a rapid increase in the number of COVID-19-related publications. Identifying trends and areas of interest using traditional review methods (eg, scoping and systematic reviews) for such a large domain area is challenging. Read More

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Exploiting lamina terminalis appearance and motion in prediction of hydrocephalus using convolutional LSTM network.

J Neuroradiol 2021 Feb 12. Epub 2021 Feb 12.

Department of Radiology, City Hospital, Bilkent, Ankara, Turkey; Department of Radiology, Yildirim Beyazit University, Ankara, Turkey; National MR Research Center (UMRAM), City Hospital, Bilkent University, Ankara, Turkey.

Background: Evaluation of the lamina terminalis (LT) is crucial for non-invasive evaluation of the CSF diversion for the treatment of hydrocephalus. Together with deep learning algorithms, morphological and physiological analyses of the LT may play an important role in the management of hydrocephalus.

Aim: We aim to show that exploiting the motion of LT can contribute to the evaluation of hydrocephalus using deep learning algorithms. Read More

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February 2021