715,181 results match your criteria coronary intervention


Outcomes of anterior vs. posterior approach to single-level lumbar spinal fusion with interbody device: An analysis of the nationwide inpatient sample.

Clin Neurol Neurosurg 2021 Nov 29;212:107061. Epub 2021 Nov 29.

Desert Regional Medical Center, Palm Springs, California, United States. Electronic address:

Background: Interbody devices have revolutionized lumbar spinal fusion surgery by improving mechanical stability and maximizing fusion potential. Several approaches for interbody fusion exist with two of the most common being anterior lumbar interbody fusion (ALIF) and posterior lumbar interbody fusion (PLIF). This study aims to compare patient data, hospital outcomes, and post-operative complications between an anterior vs. Read More

View Article and Full-Text PDF
November 2021

Safety and feasibility of a telemonitoring-guided exercise program in patients receiving cardiac resynchronization therapy.

Ann Noninvasive Electrocardiol 2021 Dec 4:e12926. Epub 2021 Dec 4.

Division of Cardiology, Department of Internal Medicine, Fujita Health University Bantane Hospital, Nagoya, Japan.

Background: Telerehabilitation is an alternative clinic-based rehabilitation. A remote monitoring (RM) system attached to a cardiac rhythm device can collect physiological data and the device function. This study aimed to evaluate the safety and feasibility of telerehabilitation supervised by an RM in patients receiving cardiac resynchronization therapy (CRT). Read More

View Article and Full-Text PDF
December 2021

Exercise-Based Cardiac Rehabilitation: Secondary Data Analyses of Mortality and Working Capacity in Germany, 2010-2017.

Sports Med Open 2021 Dec 4;7(1):88. Epub 2021 Dec 4.

Department of Applied Health Sciences, University of Applied Sciences for Health, Bochum, Germany.

Background: Exercise-based cardiac rehabilitation is safe and implemented in international cardiac rehabilitation guidelines. Evidence for long-term health effects is scarce and rare for health care service research.

Objective: The aim of this study is to evaluate the effectiveness of exercise-based phase III cardiac rehabilitation programs in improving mortality and working capacity outcomes. Read More

View Article and Full-Text PDF
December 2021

Anxiolytic Effects of Intraoperative Music Therapy in Adults Undergoing Local Anaesthetic Interventions.

Authors:
Michaela Agius

Psychiatr Danub 2021 Dec;33(Suppl 11):100-115

University of Malta, Msida, Malta,

Background: Intra-operative anxiety is a commonly experienced feeling amongst patients undergoing surgery. Moreover, conscious patients are exposed to the multiple environmental factors triggering this emotion. Apprehension and fear are common emotions interlinked with associated intra-operative anxiety. Read More

View Article and Full-Text PDF
December 2021

Effect of the therapy of amiodarone combined with atorvastatin on cardiac function of patients with acute myocardial infarction after percutaneous coronary intervention (PCI).

Pak J Pharm Sci 2021 Sep;34(5(Special)):2035-2040

Department of Cardiology, Hubei No.3, People's Hospital of Jianghan University, Hubei, China.

This study aimed to investigate the effect of the therapy of amiodarone combined with atorvastatin on cardiac function of patients with acute myocardial infarction after percutaneous coronary intervention (PCI). A total of 90 patients with acute myocardial infarction who underwent PCI in the tertiary care hospital from January 2019 to January 2020 were selected as the subjects and randomly assigned into the control group and the study group, with 45 cases in each group. All the subjects had undergone PCI. Read More

View Article and Full-Text PDF
September 2021

Instantaneous wave-free ratio for guiding treatment of nonculprit lesions in patients with acute coronary syndrome: A retrospective study.

Catheter Cardiovasc Interv 2021 Dec 4. Epub 2021 Dec 4.

Reina Sofía Hospital, Department of Cardiology, Instituto Maimónides de Investigación Biomédica de Córdoba (IMIBIC), University of Córdoba, Córdoba, Spain.

Background: The aim of this study was to analyze the feasibility of a physiological coronary evaluation with the instantaneous wave-free ratio (iFR) of nonculprit lesions in patients with acute coronary syndrome (ACS) successfully revascularized.

Methods: A multicenter registry including patients of four high-volume PCI centers with ACS and underwent successful revascularization of the culprit vessel and had other nonculprit lesions that were physiologically evaluated with the iFR between January 2017 and December 2019. The primary endpoint was a composite of cardiac death, nonfatal myocardial infarction, probable or definitive stent thrombosis and new revascularization (MACEs). Read More

View Article and Full-Text PDF
December 2021

Diabetes and treatment of chronic heart failure in a large real-world heart failure population.

ESC Heart Fail 2021 Dec 4. Epub 2021 Dec 4.

Department of Cardiology, Thorax Center, Erasmus MC, University Medical Center Rotterdam, Dr. Molewaterplein 40, Rotterdam, 3015GD, The Netherlands.

Aims: Although diabetes mellitus (DM) is a common co-morbidity in chronic heart failure (HF) patients, European data on concurrent HF and DM treatment are lacking. Therefore, we have studied the HF treatment of patients with and without DM. Additionally, with the recent breakthrough of sodium-glucose cotransporter 2 (SGLT2) inhibitors in the field of HF, we studied the potential impact of this new drug in a large cohort of HF patients. Read More

View Article and Full-Text PDF
December 2021

Effects of AST-120 on muscle health and quality of life in chronic kidney disease patients: results of RECOVERY study.

J Cachexia Sarcopenia Muscle 2021 Dec 3. Epub 2021 Dec 3.

Department of Internal Medicine, CHA Gumi Medical Center, CHA University, Gumi, Republic of Korea.

Background: The prevalence of sarcopenia is increased with declining renal function. Elevated serum indoxyl sulfate levels are associated with poor skeletal muscle conditions. We aimed to determine the effects of AST-120, the oral adsorbent of indoxyl sulfate, on sarcopenia and sarcopenia-associated factors in chronic kidney disease patients. Read More

View Article and Full-Text PDF
December 2021

Acute heart failure and iron deficiency: a prospective, multicentre, observational study.

ESC Heart Fail 2021 Dec 4. Epub 2021 Dec 4.

Department of Cardiology, Maastricht University Medical Center, Maastricht, The Netherlands.

Aims: The prevalence and the natural course of iron deficiency (ID) in acute heart failure (AHF) are still unclear. We investigated the prevalence of ID in unselected patients admitted with AHF on admission, at discharge and up to 3 months thereafter.

Methods And Results: In this prospective, multicentre, observational study, 742 patients admitted with AHF were enrolled. Read More

View Article and Full-Text PDF
December 2021

miR-222-5p promotes dysfunction of human vascular smooth muscle cells by targeting RB1.

Environ Toxicol 2021 Dec 4. Epub 2021 Dec 4.

Department of Cardiovascular Medicine, The Second Hospital of Jilin University, Jilin, China.

Background: Coronary atherosclerosis (AS) is characterized by the formation of plaque in the vessel wall. The structural and functional changes of vascular smooth muscle cells (VSMCs) can promote plaque formation and induce plaque instability.

Objective: To investigate the functions and mechanism of miR-222-5p in VSMCs under the treatment of oxidized low-density lipoprotein (ox-LDL). Read More

View Article and Full-Text PDF
December 2021

Association of clinical and social factors with risk of fracture in children with atopic dermatitis.

Pediatr Allergy Immunol 2021 Dec 4. Epub 2021 Dec 4.

Department of Pediatrics, CHA Bundang Medical Center, CHA University School of Medicine, Seongnam, Korea.

Background: Children with atopic dermatitis (AD) have multiple risk factors for accidental fractures, injuries that can lead to significant morbidity and mortality. However, little is known about the factors that mediate the relationship between AD and fracture in children.

Objective: Our purpose was to examine the association of AD with fracture and to identify potential mediating factors. Read More

View Article and Full-Text PDF
December 2021

Stenting techniques for coronary bifurcation disease: a systematic review and network meta-analysis demonstrates superiority of double-kissing crush in complex lesions.

Clin Res Cardiol 2021 Dec 4. Epub 2021 Dec 4.

Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, 100029, People's Republic of China.

Objective: This study was aimed to compare different stenting techniques for coronary bifurcation disease (CBD).

Background: Percutaneous coronary intervention (PCI) remains controversial for CBD; over the years, several stent techniques for bifurcation lesions have been used. Current guidelines recommend a provisional single-stent strategy as the preferred method for coronary artery bifurcation lesions. Read More

View Article and Full-Text PDF
December 2021

High-intensity training induces non-stoichiometric changes in the mitochondrial proteome of human skeletal muscle without reorganisation of respiratory chain content.

Nat Commun 2021 Dec 3;12(1):7056. Epub 2021 Dec 3.

Institute for Health and Sport (iHeS), Victoria University, Melbourne, VIC, 3011, Australia.

Mitochondrial defects are implicated in multiple diseases and aging. Exercise training is an accessible, inexpensive therapeutic intervention that can improve mitochondrial bioenergetics and quality of life. By combining multiple omics techniques with biochemical and in silico normalisation, we removed the bias arising from the training-induced increase in mitochondrial content to unearth an intricate and previously undemonstrated network of differentially prioritised mitochondrial adaptations. Read More

View Article and Full-Text PDF
December 2021

A low aldosterone/renin ratio and high soluble ACE2 associate with COVID-19 severity.

J Hypertens 2021 Dec 1. Epub 2021 Dec 1.

Department of Intensive Care, Haga Teaching Hospital, The Hague, The Netherlands Department of Cardiology, Unit Heart Failure and Transplant Unit, Erasmus MC University Medical Center, Rotterdam Department of Pulmonology Department of Internal Medicine, Haga Teaching Hospital, The Hague Department of Internal Medicine, Division of Vascular Medicine and Pharmacology Erasmus MC University Medical Center, Rotterdam Department of Clinical Chemistry Department of Cardiology Department of Hospital Pharmacy, Haga Teaching Hospital, The Hague Department of Clinical Chemistry, Erasmus MC University Medical Center, Rotterdam Department of Haga Science Department of Radiology, Haga Teaching Hospital, The Hague, The Netherlands.

Background: The severity of COVID-19 after SARS-CoV-2 infection is unpredictable. Angiotensin-converting enzyme-2 (ACE2) is the receptor responsible for coronavirus binding, while subsequent cell entry relies on priming by the serine protease TMPRSS2 (transmembrane protease, serine 2). Although renin-angiotensin-aldosterone-system (RAAS) blockers have been suggested to upregulate ACE2, their use in COVID-19 patients is now considered well tolerated. Read More

View Article and Full-Text PDF
December 2021

The heart & mind trial: intervention with cognitive-behavioural therapy in patients with cardiac disease and anxiety: randomised controlled trial protocol.

BMJ Open 2021 Dec 3;11(12):e057085. Epub 2021 Dec 3.

Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen N, 2200, Denmark.

Introduction: Patients with cardiac disease often experience anxiety (prevalence about 20%-25%) and have a doubled mortality risk when suffering from anxiety compared with patients without anxiety. This calls for interventions aiming to reduce anxiety.

Methods And Analysis: The Heart & Mind Trial consists of three parts: (1) screening of all hospitalised and outpatient cardiac patients with arrhythmia, heart failure or ischaemic heart disease at four university hospitals in Denmark using the Hospital Anxiety and Depression Scale-Anxiety subscale (HADS-A); Patients scoring ≥8 is invited to participate; (2) Assessment of the type of anxiety by Structured Clinical Interview for Diagnostic and Statistical Manual of Mental Disorders and (3) Randomised clinical superiority trial with blinded outcome assessment, with 1:1 randomisation to cognitive-behavioural therapy (CBT) performed by a CBT-trained cardiac nurse plus usual care or, usual care alone. Read More

View Article and Full-Text PDF
December 2021

Quality of life and disease experience in patients with heart failure with reduced ejection fraction in Spain: a mixed-methods study.

BMJ Open 2021 Dec 3;11(12):e053216. Epub 2021 Dec 3.

Department of Cardiology and Heart Failure Program, Bellvitge University Hospital, L'Hospitalet de Llobregat, Spain

Objectives: To gather insights on the disease experience of patients with heart failure (HF) with reduced ejection fraction (HFrEF), and assess how patients' experiences and narratives related to the disease complement data collected through standardised patient-reported outcome measures (PROMs). Also, to explore new ways of evaluating the burden experienced by patients and caregivers.

Design: Observational, descriptive, multicentre, cross-sectional, mixed-methods study. Read More

View Article and Full-Text PDF
December 2021

Global prevalence of dyslipidaemia in adult populations: a systematic review protocol.

BMJ Open 2021 Dec 3;11(12):e049662. Epub 2021 Dec 3.

School of Medicine, Taylor's University, Subang Jaya, Malaysia.

Introduction: Dyslipidaemia is one of the established risk factors for cardiovascular disease. Evidence from large-scale trials showed that effective treatment of dyslipidaemia can reduce all-cause and coronary mortality. To date, there is no published systematic review on the worldwide prevalence of dyslipidaemia in adults. Read More

View Article and Full-Text PDF
December 2021

Impact of health literacy in patients with cardiovascular diseases: A systematic review and meta-analysis.

Patient Educ Couns 2021 Nov 27. Epub 2021 Nov 27.

Department of Public Health, Graduate School of Health Sciences, Kobe University, Kobe, Japan; Cardiovascular stroke Renal Project (CRP), Kobe, Japan. Electronic address:

Objective: To clarify the impacts of health literacy on mortality, readmission, and quality of life (QOL) in the secondary or tertiary prevention of cardiovascular diseases (CVD) through a meta-analysis.

Methods: Six electronic databases were searched on June 11, 2020. Observational studies involving patients with CVD, health literacy as an exposure factor and mortality, readmission, or QOL as outcomes were included in this study. Read More

View Article and Full-Text PDF
November 2021

Characteristics and outcomes of octogenarians with revascularized critical limb ischemia: Impact of altered cardiac function for early mortality.

J Med Vasc 2021 Oct-Dec;46(5-6):224-231. Epub 2021 Nov 5.

Vascular medicine department, groupe hospitalier Paris Saint-Joseph, Paris, France.

Objective: Patients with critical limb ischemia (CLI) present with advanced age and end-stage organ damage, in particular heart failure. The aim of the present study is to describe clinical and biological characteristics in octogenarian patients with CLI compared to their younger counterparts and to determine the peri-procedural risk and early mortality after endovascular procedure.

Methods: From November 2013 to May 2019, 315 consecutive patients were retrospectively included. Read More

View Article and Full-Text PDF
November 2021

Individualised or liberal red blood cell transfusion after cardiac surgery: a randomised controlled trial.

Br J Anaesth 2021 Nov 30. Epub 2021 Nov 30.

Department of Anesthesiology and Critical Care Medicine, Amiens Picardy University Hospital, Amiens, France.

Background: Current practice guidelines for red blood cell (RBC) transfusion in ICUs are based on haemoglobin threshold, without consideration of oxygen delivery or consumption. We aimed to evaluate an individual physiological threshold-guided by central venous oxygen saturation ScvO.

Methods: In a randomised study in two French academic hospitals, 164 patients who were admitted to ICU after cardiac surgery with postoperative haemoglobin <9 g dl were randomised to receive a transfusion with one unit of RBCs (haemoglobin group) or transfusion only if the ScvO was <70% (individualised group). Read More

View Article and Full-Text PDF
November 2021

Targeted temperature management in cardiac surgery: a systematic review and meta-analysis on postoperative cognitive outcomes.

Br J Anaesth 2021 Nov 30. Epub 2021 Nov 30.

Department of Medicine, Anaesthesiology and Intensive Care, University of Padova, Padova, Italy.

Background: Postoperative cognitive decline occurs commonly after cardiac surgery. The available literature is inconclusive on the role of intraoperative causal or protective factors.

Methods: We systematically reviewed studies evaluating delayed neurocognitive recovery (DNR), postoperative neurocognitive disorder (NCD), stroke, and the mortality rates among patients undergoing hypothermic or normothermic cardiopulmonary bypass (CPB). Read More

View Article and Full-Text PDF
November 2021

Prognostic significance of Troponin I in patients undergoing primary percutaneous coronary intervention.

Indian Heart J 2021 Nov-Dec;73(6):737-739. Epub 2021 Sep 14.

Director Cardiology, ICVD Madras Medical Mission, Chennai, India.

This observational study investigates the prognostic significance of troponin I in patients undergoing primary percutaneous intervention (pPCI). Sequential cardiac biomarker sampling of the enrolled patients (n = 167) was performed on admission and at 6,12,24 and 48 h. Clinical characteristics, major adverse cardiac and cerebrovascular events (MACCE) (death, reinfarction, stroke and new or worsening heart failure) and left ventricular ejection fraction (LVEF) were noted on admission and 30 day follow-up. Read More

View Article and Full-Text PDF
September 2021

Establishing a diagnostic reference level of radiation dose in coronary angiography and intervention: A prospective evaluation.

Indian Heart J 2021 Nov-Dec;73(6):725-728. Epub 2021 Sep 21.

Department of Cardiology, Holy Family Hospital, New Delhi, 110025, India. Electronic address:

Introduction: Invasive Coronary Angiography (CAG) leads to significant radiation exposure to the patients. Guidelines suggest that a local landmark or Diagnostic Reference Level (DRL) for these procedures should be established for every region and country. This study attempts to create a DRL for a tertiary care hospital, acting as an interim DRL for the country/region. Read More

View Article and Full-Text PDF
September 2021

Changing spectrum of infective endocarditis in India: An 11-year experience from an academic hospital in North India.

Indian Heart J 2021 Nov-Dec;73(6):711-717. Epub 2021 Sep 16.

Department of Internal Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, India. Electronic address:

Objective: Several studies have demonstrated a shift in the spectrum of infective endocarditis (IE) in the developed world. We aimed to investigate whether demographic and microbiologic characteristics of IE have changed in India.

Design: A retrospective analysis of patients with in north India between 2010 and 2020. Read More

View Article and Full-Text PDF
September 2021

Therapeutic adherence in hypertension: Current evidence and expert opinion from India.

Indian Heart J 2021 Nov-Dec;73(6):667-673. Epub 2021 Sep 15.

Department of Neurology, Max Superspecialty Hospital, Saket, New Delhi, India. Electronic address:

Hypertension (HTN) is a globally prevalent non-communicable disease contributing significantly to cardiovascular (CV) morbidity and mortality. In achieving control of HTN, therapeutic adherence plays a crucial role. Studies from India identify varying rates of adherence to antihypertensive medications. Read More

View Article and Full-Text PDF
September 2021

Nonthyroidal illness syndrome (NTIS) in severe COVID-19 patients: role of T3 on the Na/K pump gene expression and on hydroelectrolytic equilibrium.

J Transl Med 2021 Dec 3;19(1):491. Epub 2021 Dec 3.

Department of Clinical and Surgical Translational Medicine, Sapienza University, Rome, Italy.

Background: Nonthyroidal Illness Syndrome (NTIS) can be detected in many critical illnesses. Recently, we demonstrated that this condition is frequently observed in COVID-19 patients too and it is correlated with the severity the disease. However, the exact mechanism through which thyroid hormones influence the course of COVID-19, as well as that of many other critical illnesses, is not clear yet and treatment with T4, T3 or a combination of both is still controversial. Read More

View Article and Full-Text PDF
December 2021

The relationship between IL-6 levels and the angiographic severity of coronary artery disease following percutaneous coronary intervention in acute coronary syndrome patients.

BMC Cardiovasc Disord 2021 Dec 3;21(1):578. Epub 2021 Dec 3.

Department of Cardiology, Yijishan Hospital Affiliated To Wannan Medical College, 2# West Zhe Shan Road, Wuhu, 241000, China.

Background: The present investigation was developed for the exploration of the association between IL-6 levels and acute coronary syndrome (ACS) findings upon angiographic evaluation.

Methods: A retrospective review of 346 patients suffering from chest discomfort that underwent coronary angiography was performed. The SYNergy between Percutaneous Coronary Intervention with TAXus and cardiac surgery (SYNTAX) score (SS) and SS II were used to gauge ACS severity, with ACS patients being stratified into two groups based on an SS value of 22 and the median SS II value. Read More

View Article and Full-Text PDF
December 2021

Prolonged sitting time links to subclinical atherosclerosis.

J Chin Med Assoc 2021 Nov 30. Epub 2021 Nov 30.

Division of Cardiology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan, ROC School of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan, ROC Cardiovascular Research Center, National Yang Ming Chiao Tung University, Taipei, Taiwan, ROC Institute of Pharmacology, National Yang Ming Chiao Tung University, Taipei, Taiwan, ROC Healthcare and Management Center, Taipei Veterans General Hospital, Taipei, Taiwan, ROC.

Background: This study investigates the association between daily sitting time and subclinical atherosclerosis by using coronary computed tomography angiography (CCTA).

Methods: The study enrolled 203 subjects (age 57.6 ± 8. Read More

View Article and Full-Text PDF
November 2021

Wrist pulse diagnosis of stable coronary heart disease based on acoustics waveforms.

Comput Methods Programs Biomed 2021 Nov 21;214:106550. Epub 2021 Nov 21.

Department of Gerontology, The First Affiliated Hospital of Shandong First Medical University and Shandong Provincial Qianfoshan Hospital, Jinan, Shandong, China. Electronic address:

Background And Objective: As a common pathological pulse, unsmooth pulse has important diagnostic value in traditional Chinese medicine (TCM). In modern pulse diagnosis, unsmooth pulse plays an important role in the diagnosis of disease location and nature, but there are few studies on it. In this paper, a pulse diagnosis approach based on acoustic waveforms was proposed, the wrist pulse was divided into five layers vertically for the first time. Read More

View Article and Full-Text PDF
November 2021

Drowsiness detection using portable wireless EEG.

Comput Methods Programs Biomed 2021 Nov 16;214:106535. Epub 2021 Nov 16.

Department of Electrical Engineering, Indian Institute of Technology Palakkad, Palakkad, India; Department of Electronics and Computer Engineering, The Hong Kong University of Science and Technology, Hong Kong.

Background And Objective: The ever-increasing fatality rate due to traffic and workplace accidents, resulting from drowsiness have been a persistent concern during the past years. An efficient technology capable of monitoring and detecting drowsiness can help to alleviate this concern and has potential applications in driver vigilance monitoring, vigilance monitoring in air traffic control rooms and other safety critical work places. In this paper, we present the feasibility of a wearable light weight wireless consumer grade Electroencephalogram (EEG)-based drowsiness detection. Read More

View Article and Full-Text PDF
November 2021