Dermatol Surg 2021 Apr 7. Epub 2021 Apr 7.
Skin Associates of South Florida, Coral Gables, Florida; John H. Joseph Facial Plastic and Reconstructive Surgery, Beverly Hills, California; Dermatology, SkinCare Physicians, Chestnut Hill, Massachusetts; Charlottesville Medical Research, Charlottesville, Virginia; Cosmetic Laser Dermatology and University of California-San Diego, San Diego, California; Department of Medicine, Division of Dermatology, Tennessee Clinical Research Center, Nashville, Tennessee; Juva Skin & Laser Center, New York, New York; The Education & Research Foundation, Lynchburg, Virginia; Cosmetic Surgery, Skin Specialists P.C., Omaha, Nebraska; Research, Mercy Health Research, Washington, Missouri; Research and Development, Endo Pharmaceuticals Inc, Malvern, Pennsylvania; Medical Affairs, Endo Pharmaceuticals Inc, Malvern, Pennsylvania; Biostatistics, Endo Pharmaceuticals Inc, Malvern, Pennsylvania; and Bass Plastic Surgery PLLC, New York, New York.
Background: Fibrous septae play a role in contour alterations associated with cellulite.
Objective: To assess collagenase clostridium histolyticum-aaes (CCH) for the treatment of cellulite.
Materials And Methods: Two identically designed phase 3, double-blind, randomized studies (RELEASE-1 and RELEASE-2) were conducted. Read More