8 results match your criteria copperii complexes

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An impaired mitochondrial electron transport chain increases retention of the hypoxia imaging agent diacetylbis(4-methylthiosemicarbazonato)copperII.

Proc Natl Acad Sci U S A 2012 Jan 15;109(1):47-52. Epub 2011 Dec 15.

School of Chemistry, University of Melbourne, Victoria 3010, Australia.

Radiolabeled diacetylbis(4-methylthiosemicarbazonato)copper(II) [Cu(II)(atsm)] is an effective positron-emission tomography imaging agent for myocardial ischemia, hypoxic tumors, and brain disorders with regionalized oxidative stress, such as mitochondrial myopathy, encephalopathy, and lactic acidosis with stroke-like episodes (MELAS) and Parkinson's disease. An excessively elevated reductive state is common to these conditions and has been proposed as an important mechanism affecting cellular retention of Cu from Cu(II)(atsm). However, data from whole-cell models to demonstrate this mechanism have not yet been provided. Read More

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January 2012

Microcalorimetric study of Tetrahymena growth affected by copperII complexes.

Biol Trace Elem Res 2010 Oct 13;137(1):117-24. Epub 2009 Nov 13.

Department of Applied Chemistry, School of Science, Wuhan University of Technology, Wuhan, 430070, People's Republic of China.

By means of microcalorimetry, the effect of four copper(II) complexes on Tetrahymena growth was investigated. The extent and duration of the inhibitory effect on the metabolism, judged by the rate constant, k, and the half inhibition concentration, IC(50), varied with the different complexes. The results showed that the half inhibition concentrations IC(50) of CuCl(2), (C(9)H(6)NO)(2)Cu and [Cu(phen)(2)]Cl(2)[Symbol: see text]6H(2)O were 9. Read More

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October 2010

Anion-directed synthesis of metal-organic frameworks based on 2-picolinate CuII complexes: a ferromagnetic alternating chain and two unprecedented ferromagnetic fish backbone chains.

Inorg Chem 2007 Dec 8;46(25):10771-80. Epub 2007 Nov 8.

Department of Chemistry, University College of Science, University of Calcutta, 92 A.P.C. Road, Kolkata-700009, India.

Three new polynuclear copperII complexes of 2-picolinic acid (Hpic), {[Cu2(pic)3(H2O)]ClO4}n (1), {[Cu2(pic)3(H2O)]BF4}n (2), and [Cu2(pic)3(H2O)2(NO3)]n (3), have been synthesized by reaction of the "metalloligand" [Cu(pic)2] with the corresponding copperII salts. The compounds are characterized by single-crystal X-ray diffraction analyses and variable-temperature magnetic measurements. Compounds 1 and 2 are isomorphous and crystallize in the triclinic system with space group P, while 3 crystallizes in the monoclinic system with space group P21/n. Read More

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December 2007

Novel oxygen chirality induced by asymmetric coordination of an ether oxygen atom to a metal center in a series of sugar-pendant dipicolylamine copperII complexes.

Inorg Chem 2006 Feb;45(4):1543-51

KYOUSEI Science Center, Nara Women's University, Japan.

Six sugar-pendant 2,2'-dipicolylamine (DPA) ligands (L1-3 and L'1-3) have been prepared. OH-protected and unprotected D-glucose, D-mannose, and D-xylose were attached to a DPA moiety via an O-glycoside linkage. X-ray crystallography of the copper(II) complexes (1-5) with these ligands revealed that the anomeric oxygen atom is coordinated to the metal center in the solid state, generating a chiral center at the oxygen atom. Read More

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February 2006

Terpyridine copperII-polycarboxylic acid architectures: formation of dimeric, helical, and cyclic nanostructures and their included-water molecule motifs.

Chem Commun (Camb) 2005 Sep 4(35):4405-7. Epub 2005 Aug 4.

Department of Polymer Science, The University of Akron, Akron, OH 44325-4717, USA.

New crystalline architectures have been prepared employing the propensity of terpyridine-CuII adducts to form coordination complexes with carboxylate moieties. Read More

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September 2005

Alkoxo-bridged copperII complexes as nodes in designing solid-state architectures. The interplay of coordinative and d10-d10 metal-metal interactions in sustaining supramolecular solid-state architectures.

Dalton Trans 2005 Apr 1(7):1195-202. Epub 2005 Mar 1.

University of Bucharest, Faculty of Chemistry, Inorganic Chemistry Laboratory, Str. Dumbrava Rosie nr. 23, 020464, Bucharest, Romania.

Four novel polymeric coordination networks have been obtained through self-assembly processes involving alkoxo-bridged copperII species as nodes, and anionic cyano-complexes as linkers: infinity2[{Cu2(pa)2}{M(CN)2}2](M=Ag, 1; Au, 2), (infinity)3[{Cu4(mea)4}{Au(CN)2}4.H2O]3, and (infinity)3[{Cu2(pa)2}{Ni(CN)4}](pa = deprotonated propanolamine; mea = deprotonated monoethanolamine). The supramolecular architectures of compounds 1, and 2 are sustained by argentophilic or strong aurophilic interactions. Read More

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Controllable enantioselective Friedel-Crafts reaction between indoles and alkylidene malonates catalyzed by pseudo-C3-symmetric trisoxazoline copperII complexes.

J Org Chem 2004 Feb;69(4):1309-20

State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032, China.

Pseudo-C(3)-symmetric trisoxazoline copper(II) complexes prove to be excellent catalysts in the Friedel-Crafts alkylation of indoles with alkylidene malonates. The absolute stereochemistry of this reaction is shown to be dependent on the solvent. Reactions in isobutyl alcohol afford the Friedel-Crafts alkylation adducts in excellent yields and with up to +98% ee. Read More

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February 2004

TACN-amino acid conjugates and their copperII complexes.

Inorg Chem 2003 Sep;42(18):5462-4

Department of Chemistry and Biochemistry, University of Oklahoma, 620 Parrington Oval, Norman, Oklahoma 73019, USA.

Triazacyclononane (TACN) was coupled to glycine (L(Gly)), alanine (L(Ala)), and phenylalanine (L(Phe)) via standard solution phase peptide coupling techniques. Copper(II) complexes of these new ligand-amino acid conjugates, [(CuL(Gly))(2)](ClO(4))(4) (1), [(CuL(Ala))(2)Cl](ClO(4))(3) (2), and [Cu(2)L(Phe)Cl(4)] (3), were synthesized and characterized. The X-ray crystal structures of 2 and 3 were determined. Read More

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September 2003
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