4,811 results match your criteria cooling group

Clonidine for sedation in infants during therapeutic hypothermia with neonatal encephalopathy: pilot study.

J Perinatol 2021 Sep 16. Epub 2021 Sep 16.

Center for Translational Medicine, University of Maryland School of Pharmacy, Baltimore, MD, USA.

Objective: To determine a safe dose of clonidine (CLON) to be used in infants with hypoxic ischemic encephalopathy (HIE) undergoing therapeutic hypothermia (TH).

Study Design: A pilot prospective study was performed to determine the effect of CLON on autonomic parameters, the pharmacokinetics (PK) of CLON, and the amount of morphine (MOR) given "as needed" for shivering and agitation in a cohort of infants (n = 12) with HIE undergoing TH compared to a historical control group (n = 28).

Results: The CLON group received less "as needed" MOR than the MOR-only group for agitation/shivering (p < 0. Read More

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September 2021

Chlorination in power station cooling water systems: Effect on biomass, abundance and physiology of natural phytoplankton communities.

Aquat Toxicol 2021 Aug 28;239:105954. Epub 2021 Aug 28.

CEFAS, Pakefield Road, Lowestoft NR33 0HT, Suffolk, UK.

Chlorination is a widely used method to prevent biofouling in power station cooling water systems in coastal and estuarine environments. This study evaluated the impact of chlorination together with temperature increase to simulate primary entrainment of a phytoplankton community. Biomass, diversity, and photosynthetic activity were monitored over 72 hours to establish impacts on the phytoplankton community. Read More

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Cryopreservation of Human T Lymphocytes under Fast Cooling with Controlled Ice Nucleation in Cryoprotective Solutions of Low Toxicity.

Cryobiology 2021 Sep 8. Epub 2021 Sep 8.

Institute of Biothermal and Technology, University of Shanghai for Science and Technology, Shanghai, 200093, China.

Cryopreservation of human T lymphocytes has become an essential tool for some cell-based immunotherapy. However, the cryopreservation procedure of the cells has not been systematically studied. In particular, the key factors of ice seeding and cryoprotective agents (CPA) driving the success of cryopreservation remain unclear. Read More

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September 2021

Characterisation of lamina I anterolateral system neurons that express Cre in a Phox2a-Cre mouse line.

Sci Rep 2021 Sep 9;11(1):17912. Epub 2021 Sep 9.

Institute of Neuroscience and Psychology, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, G12 8QQ, UK.

A recently developed Phox2a::Cre mouse line has been shown to capture anterolateral system (ALS) projection neurons. Here, we used this line to test whether Phox2a-positive cells represent a distinct subpopulation among lamina I ALS neurons. We show that virtually all lamina I Phox2a cells can be retrogradely labelled from injections targeted on the lateral parabrachial area (LPb), and that most of those in the cervical cord also belong to the spinothalamic tract. Read More

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September 2021

Interaction of MS prevalence, radon gas concentration, and patient nutrition: a case-control study.

Sci Rep 2021 Sep 9;11(1):17906. Epub 2021 Sep 9.

Department of Environmental Health Engineering, Environmental Science and Technology Research Center, School of Public Health, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.

In general, ecological findings indicate a positive correlation between MS and the intake of certain foods. This study aimed to investigate the relationship between radon (Rn) gas concentration and nutrition of patients in food groups with MS. Demographic information, diet, and building characteristics were collected by a questionnaire. Read More

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September 2021

Retrospective analysis of hops toxicosis in dogs (2002-2014): 71 cases.

J Vet Emerg Crit Care (San Antonio) 2021 Sep 9. Epub 2021 Sep 9.

Department of Clinical Sciences, Cummings School of Veterinary Medicine at Tufts University, North Grafton, Massachusetts, USA.

Objective: To describe a population of dogs with hops toxicosis, including clinical signs observed, treatments performed, patient outcome, and overall prognosis. Clinical findings and treatment interventions were evaluated for their potential effects on outcome. This study also aims to review hops toxicosis and treatment options. Read More

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September 2021

Chronic thromboembolic pulmonary hypertension: the impact of advances in perioperative techniques in patient outcomes.

J Bras Pneumol 2021 3;47(5):e20200435. Epub 2021 Sep 3.

Departamento de Cardiopneumologia, Instituto do Coração, Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo (SP), Brasil.

Objectives: Pulmonary endarterectomy (PEA) is the gold standard treatment for chronic thromboembolic pulmonary hypertension (CTEPH). This study aimed at reporting outcomes of CTEPH patients undergoing PEA within 10 years, focusing on advances in anesthetic and surgical techniques.

Methods: We evaluated 102 patients who underwent PEA between January 2007 and May 2016 at the Instituto do Coração do Hospital das Clínicas da Universidade de São Paulo. Read More

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September 2021

Deep-Freezing Temperatures During Irradiation Preserves the Compressive Strength of Human Cortical Bone Allografts: A Cadaver Study.

Clin Orthop Relat Res 2021 Sep 6. Epub 2021 Sep 6.

Bone Bank, National Orthopaedic Centre of Excellence in Research and Learning, Kuala Lumpur, Malaysia.

Background: Gamma irradiation, which minimizes the risk of infectious disease transmission when human bone allograft is used, has been found to negatively affect its biomechanical properties. However, in those studies, the deep-freezing temperature during irradiation was not necessarily maintained during transportation and sterilization, which may have affected the findings. Prior reports have also suggested that controlled deep freezing may mitigate the detrimental effects of irradiation on the mechanical properties of bone allograft. Read More

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September 2021

Efficacy of scalp cooling for prevention of chemotherapy induced alopecia: a systematic review and meta-analysis.

Eur Rev Med Pharmacol Sci 2021 Aug;25(16):5090-5103

Department of Interventional Radiotherapy, Huzhou Central Hospital, Affiliated Central Hospital Huzhou University, Huzhou, Zhejiang Province, P.R. China.

Objective: The aim of the study was to compare the risk of chemotherapy induced alopecia among patients with scalp cooling therapy, compared to those that did not receive scalp cooling.

Materials And Methods: A systematic search was conducted in the PubMed, Scopus, Cochrane Database of Systematic Reviews and Google scholar databases. Studies, preferably randomized controlled trials, that compared scalp cooling with no scalp cooling (control) for risk of alopecia or hair loss in patients undergoing chemotherapy were considered for inclusion. Read More

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Health vs. wealth: Employer, employee and policy-maker perspectives on occupational heat stress across multiple European industries.

Temperature (Austin) 2021 14;8(3):284-301. Epub 2020 Dec 14.

Department of Nutrition, Exercise and Sports, University of Copenhagen, Copenhagen, Denmark.

Successful implementation of cooling strategies obviously depends on identifying effective interventions, but in industrial settings, it is equally important to consider feasibility and economic viability. Many cooling interventions are available, but the decision processes affecting adoption by end-users are not well elucidated. We therefore arranged two series of meetings with stakeholders to identify knowledge gaps, receive feedback on proposed cooling interventions, and discuss factors affecting implementation of heat-health interventions. Read More

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December 2020


J Evid Based Dent Pract 2021 09 4;21(3):101588. Epub 2021 Jun 4.

Assistant professor, Dental research center, Department of Pediatric Dentistry, Dental Research Institute, School of Dentistry, Isfahan University of Medical sciences, Isfahan, Iran. Electronic address:

Objectives: Several methods, including cooling of the injection site, have been proposed for pain control during the dental local anesthetic injection. This systematic review aimed to evaluate the scientific evidence on the precooling of the injection site to reduce pediatric dental injection pain.

Data Sources: The search terms were selected according to the Medical Subject Headings and non-Medical Subject Headings. Read More

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September 2021

Increased risk of chronic fatigue and hair loss following COVID-19 in individuals with hypohidrotic ectodermal dysplasia.

Orphanet J Rare Dis 2021 09 3;16(1):373. Epub 2021 Sep 3.

Department of Pediatrics, University Hospital Erlangen, University of Erlangen-Nürnberg, Loschgestr. 15, 91054, Erlangen, Germany.

Background: Hypohidrotic ectodermal dysplasia (HED) is a group of genodermatoses in which deficient ectodysplasin A signalling leads to maldevelopment of skin appendages, various eccrine glands, and teeth. Individuals with HED often have disrupted epithelial barriers and, therefore, were suspected to be more susceptible to coronavirus infection.

Methods: 56 households with at least one member who had coronavirus disease of 2019 (COVID-19) were enrolled in a longitudinal study to compare the course of illness, immune responses, and long-term consequences of severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) infection in HED patients (n = 15, age 9-52 years) and control subjects of the same age group (n = 149). Read More

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September 2021

Heat-Health Behavior Change During Summer 2020 in African American Alabama Residents.

Am J Public Health 2021 08;111(8):1443-1447

Suwei Wang and Julia M. Gohlke are with the Department of Population Health Sciences, Virginia Polytechnic Institute and State University, Blacksburg. Suwei Wang is also with the Translational Biology, Medicine, and Health Program, Virginia Polytechnic Institute and State University. Ethel Johnson is with the Central Alabama Community Health Improvement League, Camden. Sheila Tyson is with Friends of West End, Birmingham, AL.

To investigate how heat-health behaviors changed in summer 2020 compared with previous summers, our community-academic partnership conducted telephone surveys to collect data on cooling behaviors, safety concerns, and preferences for cooling alternatives for 101 participants living in Alabama. Participants indicating they would visit cooling centers declined from 23% in previous summers to 10% in summer 2020. The use of cooling centers and other public spaces may be less effective in reducing heat-related illness because of safety concerns amid the COVID-19 pandemic and police brutality. Read More

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Ischemic hypoxic encephalopathy: The role of MRI of neonatal injury and medico-legal implication.

Forensic Sci Int 2021 Aug 20;327:110968. Epub 2021 Aug 20.

Department of Radiology, University of Palermo, Via del Vespro 129, 90127 Palermo, Italy.

Hypoxic ischemic encephalopathy is one of the major causes of neonatal death and neurological disability in the child, and represents the most common birth injury claim. Intrapartum asphyxia often leads to several long-term sequalae, such as cerebral palsy and/or developmental delay, epilepsy. Through the neuroimaging it's possible to identify and define the different lesioned pictures and provide useful elements to establish the moment in which the damage occurred; indeed, timing of injury is a key element in the legal arena. Read More

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Safety of Selective Intracoronary Hypothermia During Primary Percutaneous Coronary Intervention in Patients With Anterior STEMI.

JACC Cardiovasc Interv 2021 Aug 17. Epub 2021 Aug 17.

Department of Cardiology, Catharina Hospital, Eindhoven, the Netherlands. Electronic address:

Objectives: The aim of this study was to determine the safety of selective intracoronary hypothermia during primary percutaneous coronary intervention (PPCI) in patients with anterior ST-segment elevation myocardial infarction (STEMI).

Background: Selective intracoronary hypothermia is a novel treatment designed to reduce myocardial reperfusion injury and is currently being investigated in the ongoing randomized controlled EURO-ICE (European Intracoronary Cooling Evaluation in Patients With ST-Elevation Myocardial Infarction) trial (NCT03447834). Data on the safety of such a procedure during PPCI are still limited. Read More

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Detection of Defects in Geomembranes Using Quasi-Active Infrared Thermography.

Sensors (Basel) 2021 Aug 9;21(16). Epub 2021 Aug 9.

Department of Mechanical and Aerospace Engineering, Monash University, Wellington Rd, Clayton, VIC 3800, Australia.

High-density polyethylene geomembranes are employed as covers for the sewage treatment lagoons at Melbourne Water Corporation's Western Treatment Plant, to harvest the biogas produced during anaerobic degradation, which is then used to generate electricity. Due to its size, inspecting the cover for defects, particularly subsurface defects, can be challenging, as well as the potential for the underside of the membrane to come into contact with different substrates, viz. liquid sewage, scum (consolidated solid matter), and biogas. Read More

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Effects of cooling systems on physiological responses and intestinal microflora in early gestating sows exposed to high-temperature stress.

J Anim Sci Technol 2021 Jul 31;63(4):904-918. Epub 2021 Jul 31.

Swine Science Division, National Institute of Animal Science, Rural Development Administration, Cheonan 31000, Korea.

This study was conducted to investigate the effect of cooling systems on reproductive performance, body temperature, blood metabolites, and the intestinal microbiome in early gestating sows exposed to high ambient temperature. In total, 39 pregnant sows (Landrace × Yorkshire; 2 parities) were randomly assigned to and maintained in the following three treatment groups (13 sows per group) over days 0 to 35 of pregnancy: (i) air cooling (AC; 26.87 ± 1. Read More

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Reproducibility of Skin Temperature Response after Cold Stress Test Using the Game Ready System: Preliminary Study.

Int J Environ Res Public Health 2021 08 5;18(16). Epub 2021 Aug 5.

Research Group in Medical Physics (GIFIME), Department of Physiology, Universitat de València, 46010 Valencia, Spain.

The objective of this preliminary study was to determine the reproducibility of lower limbs skin temperature after cold stress test using the Game Ready system. Skin temperature of fourteen participants was measured before and after cold stress test using the Game Ready system and it was repeated the protocol in four times: at 9:00, at 11:00, at 19:00, and at 9:00 h of the posterior day. To assess skin temperature recovery after cold stress test, a logarithmic equation for each region was calculated, and constant (β) and slope (β) coefficients were obtained. Read More

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SEM Evaluation of Tooth Surface after a Composite Filling Removal Using Er:YAG Laser, Drills with and without Curettes, and Optional EDTA or NaOCl Conditioning.

Materials (Basel) 2021 Aug 10;14(16). Epub 2021 Aug 10.

Department of Pediatric Dentistry and Preclinical Dentistry, Wroclaw Medical University, Krakowska 26, 50-425 Wroclaw, Poland.

(1) Background: This study aimed to evaluate the microporosity of the tooth surface structure adjacent to the cemento-enamel junction (CEJ) after the removal of composite fillings with a drill in comparison with removal by an Er:YAG laser and after cleaning with a periodontal curette, chemical EDTA and NaOCl (sodium hypochlorite) conditioning. (2) Methods: The research material consisted of 30 extracted premolars with cervical composite fillings. The teeth were divided into six groups according to the method of tooth preparation: group G1 ( = 5)-a diamond drill; group G2 ( = 5)-a diamond drill + curette; group G3 ( = 5)-a diamond drill + 24% EDTA (PrefGel, Straumann, Switzerland); group G4 ( = 5)-an Er:YAG laser (LightWalker, Fotona, Ljubljana, Slovenia) set with the following parameters: power: 1. Read More

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Potential of Fermentation and Vacuum Packaging Followed by Chilling to Preserve Black Soldier Fly Larvae ().

Insects 2021 Aug 10;12(8). Epub 2021 Aug 10.

Research Group for Insect Production and Processing, Department of Microbial and Molecular Systems (M²S), Geel Campus, KU Leuven, 2440 Geel, Belgium.

Black soldier fly larvae () are currently reared at an industrial scale, mainly as a feed ingredient. The logistic chain not only involves the production of larvae, but also stabilisation, storage, and transport. The aim of this work was to study fermentation and vacuum packaging of larvae as potential preservation technologies. Read More

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Biosafety devices to control the spread of potentially contaminated dispersion particles. New associated strategies for health environments.

PLoS One 2021 26;16(8):e0255533. Epub 2021 Aug 26.

Faculdade São Leopoldo Mandic, Instituto São Leopoldo Mandic, Campinas-SP, Brazil.

Dental procedures produce a large amount of spatter and aerosols that create concern for the transmission of airborne diseases, such as Covid-19. This study established a methodology with the objective of evaluating new associated strategies to reduce the risk of cross-transmission in a health environment by simulating spread of potentially contaminated dispersion particles (PCDP) in the environment. This crossover study, was conducted in a school clinic environment (4 clinics containing 12 dental chairs each). Read More

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September 2021

A hybrid thermal management system for high power lithium-ion capacitors combining heat pipe with phase change materials.

Heliyon 2021 Aug 12;7(8):e07773. Epub 2021 Aug 12.

Battery Innovation Center, MOBI Research Group, Vrije Universiteit Brussel, Pleinlaan 2, 1050, Brussels, Belgium.

Lithium-ion capacitor (LiC) technology is an energy storage system (ESS) that combines the working mechanism of electric double-layer capacitors (EDLC) and lithium-ion batteries (LiB). When LiC is supposed to work under high power applications, the inevitable heat loss threatens the cell's performance and lifetime. Therefore, a proper thermal management system (TMS) can remove the generated heat of the LiC during high cycling conditions. Read More

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A controllable double-cycle cryogenic device inducing hypothermia for laparoscopic orthotopic kidney transplantation in swine.

Transl Androl Urol 2021 Jul;10(7):3046-3055

Department of Urology, Beijing Chaoyang Hospital, Capital Medical University, Beijing, China.

Background: It is necessity to maintain donor kidneys at a low temperature for laparoscopic orthotopic kidney transplantation (LOKT). We recently designed a controllable double-cycle cryogenic device (DCD) with a safer and more effective cooling setting. This study aimed to evaluate the safety and efficacy of this device in a swine model. Read More

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Association Between Early Stage-Related Factors and Mortality in Patients with Exertional Heat Stroke: A Retrospective Study of 214 Cases.

Int J Gen Med 2021 17;14:4629-4638. Epub 2021 Aug 17.

Medical School of Chinese PLA, Beijing, People's Republic of China.

Objective: The purpose of this study is to evaluate the factors involved in the early stage of exertional heat stroke (EHS) that are associated with mortality.

Methods: In this retrospective, case-control study, patients from 11 tertiary medical centers in China were enrolled from January 1, 2012, to December 31, 2019. Demographic information, underlying diseases, ambient temperature, and relative humidity, clinical manifestations, initial body temperature, time from onset to diagnosis of EHS (including suspected), and the duration of body temperature > 38°C of all enrolled patients were recorded. Read More

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Thermoregulatory and cardiovascular responses in the elderly towards a broad range of gradual air temperature changes.

J Therm Biol 2021 Jul 24;99:103007. Epub 2021 May 24.

Total System Laboratory, Tsukuba, Japan.

This study aimed to determine age-related differences in thermoregulatory and cardiovascular responses to a wide range of gradual ambient temperature (T) changes. Morphologically matched normotensive elderly and young males participated. The participants wearing only shorts rested during the 3-h experiment. Read More

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Recent advances in donkey sperm vitrification.

Manuel Hidalgo

Reprod Domest Anim 2021 Aug 21. Epub 2021 Aug 21.

Veterinary Reproduction Group, Faculty of Veterinary Medicine, Department of Animal Medicine and Surgery, University of Cordoba, Cordoba, Spain.

Artificial insemination (AI) with cryopreserved semen is an important tool to preserve endangered species, including European donkey breeds. Sperm vitrification is an alternative method to conventional freezing using high cooling rates and non-permeable cryoprotectant agents (CPAs). In donkeys, sperm vitrification was firstly developed in spheres by directly dropping the sperm (30 µl) into the liquid nitrogen. Read More

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Residential Net-Zero Energy Buildings: Review and Perspective.

Renew Sustain Energy Rev 2021 May;142

National Institute of Standards and Technology, Engineering Laboratory, Energy and Environment Division, HVAC&R Equipment Performance Group, USA.

Advancements in residential net-zero energy buildings (NZEBs) could significantly reduce energy consumption and greenhouse gas emissions. NZEB design considerations broadly categorize into energy infrastructure connections, renewable energy sources, and energy-efficiency measures. There is a lack of systematic literature review focused on recent progress in residential NZEBs. Read More

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A unifying model to estimate the effect of heat stress in the human innate immunity during physical activities.

Sci Rep 2021 Aug 17;11(1):16688. Epub 2021 Aug 17.

National Center of Cognitive Research, ITMO University, St. Petersburg, Russian Federation.

Public health is threatened by climate change and extreme temperature events worldwide. Differences in health predispositions, access to cooling infrastructure and occupation raises an issue of heat-related health inequality in those vulnerable and disadvantaged demographic groups. To address these issues, a comprehensive understanding of the effect of elevated body temperatures on human biological systems and overall health is urgently needed. Read More

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Improved Micro-X-ray Fluorescence Confocal Imaging of Two-Dimensional Distribution of Arsenic Concentration in Cucumber Hypocotyls Using Synchrotron Radiation.

Anal Chem 2021 08 17;93(34):11660-11668. Epub 2021 Aug 17.

X-ray Microspectroscopy and Imaging Group (XMI), Department of Chemistry, Ghent University, Krijgslaan 281 S12, Ghent B-9000, Belgium.

An optimized micro-X-ray fluorescence confocal imaging (μXRF-CI) analytical method has been developed to determine the 2D distribution of elemental composition in small (1-3 mm) biological objects at a 10-20 μm spatial resolution. Plants take up chemical elements from soil, and the vascular system transports them toward shoots. In order to obtain biochemical information related to this biological process, 2D distributions of chemical elements in roots and in hypocotyls of cucumber plants were analyzed by synchrotron radiation based on micro-X-ray fluorescence computer tomography and μXRF-CI techniques. Read More

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Scalp cooling for reducing alopecia in gynecology oncology patients treated with dose-dense chemotherapy: A pilot project.

Gynecol Oncol Rep 2021 Aug 27;37:100842. Epub 2021 Jul 27.

Division of Gynecologic Oncology, Segal Cancer Centre, Jewish General Hospital, McGill University, Montreal, Québec, Canada.

Objective: Determine the efficacy of scalp cooling for the prevention of chemotherapy-induced alopecia in gynecology oncology patients.

Methods: This prospective pilot study included patients diagnosed with a gynecological malignancy that received DigniCap™ scalp cooling. Patients were divided into two groups based on chemotherapy regimen: Carboplatin with area under the curve (AUC) 5-6 every three weeks and (1) conventional Paclitaxel 175 mg/m every three weeks or (2) Paclitaxel 80 mg/m weekly. Read More

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