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Hot-melt extruded copper sulfate affects the growth performance, meat quality, and copper bioavailability of broiler chickens.

Anim Biosci 2021 Jun 24. Epub 2021 Jun 24.

College of Animal Life Sciences, Kangwon National University, Chuncheon 24341, Korea.

Objective: This study was conducted to evaluate the effects of the supplementation of diets of broiler chickens with hot-melt extruded CuSO4 (HME-Cu) on their growth performance, nutrient digestibility, gut microbiota, small intestinal morphology, meat quality, and copper (Cu) bioavailability.

Methods: A total of 225 broilers (Ross 308), one-day old and initial weight 39.14 g, were weighed and distributed between 15 cages (15 birds per cage) in a completely randomized experimental design with 3 treatments (diets) and 5 replicates per treatment. Read More

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Assessment of technological characteristics and microbiological quality of marinated turkey meat with the use of dairy products and lemon juice.

Anim Biosci 2021 Jun 24. Epub 2021 Jun 24.

Department of Fruit Science, Viticulture and Enology, Faculty of Horticulture and Landscape Engineering, Slovak University of Agriculture, 949 76 Nitra, Slovakia.

Objective: The aim of this study was to evaluate the effect of marinating turkey meat with buttermilk and acid whey on the technological traits and microbiological quality of the product.

Methods: Slices of turkey meat muscles were marinated for 12 hours in buttermilk (n=30), acid whey (n=30) and comparatively, in lemon juice (n=30). The control group (n=30) consisted of unmarinated slices of turkey breast muscles. Read More

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Effect of dietary pumpkin (Cucurbita moschata) seed meal on layer performance and egg quality characteristics.

Anim Biosci 2021 Jun 24. Epub 2021 Jun 24.

Department of Chemistry and Animal Nutrition Physiology, National Research and Development Institute for Animal Biology and Nutrition, Balotesti, Ilfov, 077015, Romania.

Objective: The objective of this study was to investigate the of dietary pumpkin (Cucurbita moschata) seed meal (PSM) on laying performance, quality, fatty acids, cholesterol, antioxidant compounds and shelf life of eggs.

Methods: Eighty Tetra SL laying hens, 50-week-old, were randomly divided into two equal groups, having 10 replicates with 4 birds in each. The control (CON) treatment was fed with basal diet, while experimental treatment was fed a diet with 9% pumpkin seed meal (PSM), for a 6 week period. Read More

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Polycystic ovary syndrome and infertility: an update.

Int J Adolesc Med Health 2021 Jul 22. Epub 2021 Jul 22.

Regional Research Institute of Unani Medicine, Srinagar, Jammu and Kashmir, India.

Polycystic ovarian syndrome is the most well-known endocrine condition among women of this generation (PCOS). Symptoms of hyperandrogenism, irregular menstrual periods, and insulin resistance are all traits associated with PCOS. In women with PCOS, the chance of having problems including infertility, insulin resistance, and type 2 diabetes increases. Read More

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Prenatal case of Simpson-Golabi-Behmel syndrome with a de novo 370Kb-sized microdeletion of Xq26.2 compassing partial GPC3 gene and review.

Mol Genet Genomic Med 2021 Jul 22:e1750. Epub 2021 Jul 22.

Department of Medical Genetics, Hunan Provincial Maternal and Child Health Care Hospital, Changsha, Hunan, China.

Background: Simpson-Golabi-Behmel syndrome type 1 (SGBS1) is a rare X-linked recessive disorder characterized by pre- and postnatal overgrowth and a broad spectrum of anomalies including craniofacial dysmorphism, heart defects, renal, and genital anomalies. Due to the ultrasound findings are not pathognomonic for this syndrome, most clinical diagnosis of SGBS1 are made postnatally.

Methods: A pregnant woman with abnormal prenatal sonographic findings was advised to perform molecular diagnosis. Read More

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Multiple sclerosis is associated with higher comorbidity and healthcare resource use: a population-based, case-control study in a western Mediterranean region.

Eur J Neurol 2021 Jul 22. Epub 2021 Jul 22.

Servei de Neurología-Neuroimmunología, Centre d'Esclerosi Múltiple de Catalunya (Cemcat), Vall d'Hebron Hospital Universitari, Barcelona, Spain.

Background: Comorbidities are common in multiple sclerosis (MS), and have been associated with worse outcomes and increased healthcare resource usage. We studied the frequency of comorbidities and adverse health behaviors (AHB) in MS patients in the Mediterranean region of Catalonia.

Methods: Population-based, case-control study using primary healthcare information covering 80% of Catalonia's population. Read More

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Genome-wide survey of the F-box/Kelch (FBK) members and molecular identification of a novel FBK gene TaAFR in wheat.

PLoS One 2021 22;16(7):e0250479. Epub 2021 Jul 22.

College of Life Sciences/Key Laboratory of Hebei Province for Plant Physiology and Molecular Pathology, Hebei Agricultural University, Baoding, Hebei, China.

F-box proteins play critical roles in plant responses to biotic/abiotic stresses. In the present study, a total of 68 wheat F-box/Kelch (TaFBK) genes, unevenly distributed across 21 chromosomes and encoding 74 proteins, were identified in EnsemblPlants. Protein sequences were compared with those of Arabidopsis and three cereal species by phylogenetic and domain analyses, where the wheat sequences were resolved into 6 clades. Read More

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Surmising synchrony of sound and sight: Factors explaining variance of audiovisual integration in hurdling, tap dancing and drumming.

PLoS One 2021 22;16(7):e0253130. Epub 2021 Jul 22.

Department of Psychology, University of Muenster, Muenster, Germany.

Auditory and visual percepts are integrated even when they are not perfectly temporally aligned with each other, especially when the visual signal precedes the auditory signal. This window of temporal integration for asynchronous audiovisual stimuli is relatively well examined in the case of speech, while other natural action-induced sounds have been widely neglected. Here, we studied the detection of audiovisual asynchrony in three different whole-body actions with natural action-induced sounds-hurdling, tap dancing and drumming. Read More

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Retrobulbar Hyaluronidase Injection: Does It Reach the Eye?

Ophthalmic Plast Reconstr Surg 2021 Jul 21. Epub 2021 Jul 21.

Jhaveri Microbiology Centre, Brien Holden Eye Research Centre Ophthalmic Plastic Surgery Service, L.V. Prasad Eye Institute, Hyderabad, India.

Purpose: To determine if retrobulbar injection of hyaluronidase reaches the vitreous cavity, and to determine its concentration in the vitreous.

Methods: Prospective case-control study. Patients undergoing evisceration with implant for noninfective blind eyes were enrolled in the study. Read More

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Effect of Sustained Interventions from Infancy to Toddlerhood in Children with Cleft Lip and Palate for Preventing Early Childhood Caries.

Caries Res 2021 Jul 22:1-9. Epub 2021 Jul 22.

Department of Pediatric and Preventive Dentistry, Pushpagiri College of Dental Sciences, Thiruvalla, India.

The study aimed to evaluate the effectiveness of sustained interventions in children with cleft lip and palate (CLP) for preventing early childhood caries (ECC). This prospective, nonrandomized interventional cohort study was conducted in infants aged 0-12 months with congenital CLP. Interventions were given to parents/primary caregivers in the form of combined oral health-care measures (sterile wet gauze piece, finger brush, toothbrush, and toothpaste) by a motivational interviewing approach. Read More

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A perspective on hospital-acquired (nosocomial) infection control of COVID-19: usefulness of spatial separation between wards and airborne isolation unit.

J Breath Res 2021 Jul 22. Epub 2021 Jul 22.

Emergency Medicine and Critical Care, Saitama Medical Center, 1981 Kamoda, Kawagoe, Saitama, 350-8550, JAPAN.

The coronavirus disease 2019 (COVID-19) pandemic has imposed a considerable burden on hospitals and healthcare workers (HCWs) worldwide, increasing the risk of outbreaks and nosocomial transmission to "non-COVID-19" patients, who represent the highest-risk population in terms of mortality, and HCWs. Since HCWs are at the interface between hospitals on the one hand and the community on the other, they are potential reservoirs, carriers, or victims of severe acute respiratory syndrome coronavirus 2 cross-transmission. In addition, there has been a paradigm shift in the management of viral respiratory outbreaks, such as the widespread testing of patients and HCWs, including asymptomatic individuals. Read More

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Performance tunability of field-effect transistors using MoSSealloys.

Nanotechnology 2021 Jul 22. Epub 2021 Jul 22.

Centre for Nano Science and Engineering, Indian Institute of Science, CeNSE, Indian Institute of Science, CV Raman Rd, Bangalore, Karnataka, 560012, INDIA.

Ultra-thin channel materials with excellent tunability of their electronic properties are necessary for the scaling of electronic devices. Two-dimensional materials such as transition metal dichalcogenides (TMDs) are ideal candidates for this due to their layered nature and great electrostatic control. Ternary alloys of these TMDs show composition-dependent electronic structure, promising excellent tunability of their properties. Read More

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Effects of valproate, an HDAC inhibitor, on the expression of folate carriers and folate metabolism-related genes in the placenta of rats.

Drug Metab Pharmacokinet 2021 Jun 7;40:100409. Epub 2021 Jun 7.

Laboratory of Clinical Pharmaceutics & Therapeutics, Division of Pharmasciences, Faculty of Pharmaceutical Sciences, Hokkaido University. Electronic address:

Valproate (VPA), an antiepileptic drug, is known to inhibit histone deacetylases (HDACs). Exposure to VPA during pregnancy increases several fetal risks. The maintenance of folate level during pregnancy is essential for adequate fetal development, and the placenta plays a critical role in supplying nutrients to the fetus. Read More

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Optimizing the microstructure of a new machinable bioactive glass-ceramic.

J Mech Behav Biomed Mater 2021 Jul 13;122:104695. Epub 2021 Jul 13.

Vitreous Materials Laboratory, Materials Engineering Department, Federal University of São Carlos, São Carlos, SP, Brazil.

Objectives: This study aimed to optimize the crystallization process and the microstructure of a new bioactive glass-ceramic (GC) previously developed by our research group to obtain machinable glass-ceramics.

Methods: Differential scanning calorimetry (DSC) analyses were conducted to explore the characteristic temperatures and construct a semi-quantitative nucleation curve. The GC specimens were characterized by X-ray diffraction (XRD) and Rietveld refinement. Read More

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Reductive soil disinfestation attenuates antibiotic resistance genes in greenhouse vegetable soils.

J Hazard Mater 2021 Jul 13;420:126632. Epub 2021 Jul 13.

School of Ecology and Environment, Northwestern Polytechnical University, 710000 Xi'an, Shaanxi, China.

Reductive soil disinfestation (RSD) is an emerging technique that ameliorates soil degradation, but its effects against antibiotic resistance genes (ARGs) were unclear. Here, we examined soil properties, ARG types and numbers, and ARG profiles, and bacterial community compositions following 4 soil treatments: control; straw addition (SA); water flooding (WF); and RSD, both straw addition and water flooding. The results showed that the numbers of ARG types and subtypes decreased by 10. Read More

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Acceleration of polychlorinated biphenyls remediation in soil via sewage sludge amendment.

J Hazard Mater 2021 Jul 13;420:126630. Epub 2021 Jul 13.

Department of Civil and Environmental Engineering, National University of Singapore, Block E2-02-13, 1 Engineering Drive 3, Singapore 117576, Singapore. Electronic address:

Bioremediation of polychlorinated biphenyls (PCBs) is impeded by difficulties in massively cultivating bioinoculant. Meanwhile, sewage sludge is rich in pollutant-degrading microorganisms and nutrients, drawing our attention to investigate their potential to be used as a supplement for bioremediation of PCBs. Here we reported extensive microbial reductive dechlorination of PCBs by waste activated sludge (WAS) and digestion sludge (DS), which were identified to harbor multiple putative organohalide-respiring bacteria (i. Read More

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Biodegradable and re-usable sponge materials made from chitin for efficient removal of microplastics.

J Hazard Mater 2021 Jul 8;420:126599. Epub 2021 Jul 8.

Institute of Coastal Environmental Pollution Control, Key Laboratory of Marine Environment and Ecology, Ministry of Education, Ocean University of China, Qingdao 266100, China; Laboratory for Marine Ecology and Environmental Science, Qingdao National Laboratory for Marine Science and Technology, Qingdao 266237, China. Electronic address:

Microplastics have attracted widespread attention due to their detrimental effects on organisms, and their efficient removal poses great challenges, especially those smaller than 3 µm that are more harmful for aquatic biota. Herein, the chitin based sponges with interconnected pores, excellent elasticity and mechanical durability were fabricated and composed with graphene oxide (GO) and oxygen-doped carbon nitride (O-CN). The chitin based sponges could effectively remove different functionalized microplastics (~1 µm) at pH 6-8, including carboxylate-modified polystyrene (PS-COOH), amine-modified polystyrene (PS-NH), and polystyrene (PS). Read More

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Preparation and characterization of magnetic modified bone charcoal for removing Cu ions from industrial and mining wastewater.

J Environ Manage 2021 Jul 20;297:113221. Epub 2021 Jul 20.

College of Safety and Environmental Engineering, Shandong University of Science and Technology, Qingdao 266590, China; State Key Laboratory of Mining Disaster Prevention and Control Co-founded by Shandong Province and the Ministry of Science and Technology, Shandong University of Science and Technology, Qingdao 266590, China.

Heavy metal water pollution is an urgent global problem to be addressed. Copper ions are common toxic heavy metal pollutants in wastewater. In order to remove the excessive copper ions in wastewater, in this study, chicken bone charcoal was modified by sodium dodecyl sulfonate and combined with magnetic nanoparticles prepared with ferric chloride hexahydrate and ferrous sulfate heptahydrate to produce a high efficiency adsorbent. Read More

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Long term follow up in 183 high grade meningioma: A single institutional experience.

Clin Neurol Neurosurg 2021 Jul 10;207:106808. Epub 2021 Jul 10.

Neuro-oncology Unit, Department of Clinical Neurosciences, Fondazione IRCCS Istituto Neurologico Carlo Besta, Via Celoria, 11, 20133 Milan, Italy.

Introduction: Meningiomas are usually considered benign lesions, however a proportion of them shows a more aggressive behavior, defined high-grade meningiomas (HGM). Effective medical treatments are lacking, especially at the time of recurrence.

Methods: Through a retrospective analysis, we examined epidemiological, diagnostic, therapeutic, recurrence information and survival data of HGM treated at our institution between 2010 and 2018. Read More

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Chondrosarcoma arising in monostotic fibrous dysplasia treated with total femur resection and megaprothesis: A case report.

Int J Surg Case Rep 2021 Jul 9;85:106194. Epub 2021 Jul 9.

Department of Orthopaedic and Traumatology, Faculty of Medicine Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Indonesia. Electronic address:

Introduction: Fibrous dysplasia is tumor like lesions of bone which develop as substitution of bone by an expansion of fibrous connective tissue mixed with hard trabeculae. Chondrosarcomas is one of common malignant primary bone tumor derived from heterogenous group of neoplasm producing chondroid matrix. Chondrosarcoma arising in fibrous dysplasia, especially in monostotic fibrous dysplasia is a very rare case. Read More

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Maternal urinary cadmium concentrations in early pregnancy in relation to prenatal and postpartum size of offspring.

J Trace Elem Med Biol 2021 Jul 16;68:126823. Epub 2021 Jul 16.

National Institute for Occupational Health and Poison Control, Chinese Center for Disease Control and Prevention, Beijing, China. Electronic address:

Background: The impacts of environmental cadmium (Cd) exposure on birth size parameters including weight, length and head circumference (HC) have been reported in multiple studies. However, little remains known of the impacts of maternal Cd exposure during pregnancy on size during in utero development and during early childhood. The aim of this study was to comprehensively investigate impacts of maternal Cd exposure during pregnancy on the size of offspring in utero (from 24 weeks pregnancy) until six months of age. Read More

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Efficacy of double antibiotics in hydroxypropyl methylcellulose for bactericidal activity against Enterococcus faecalis and Streptococcus gordonii in biofilm.

Arch Oral Biol 2021 Jul 16;129:105210. Epub 2021 Jul 16.

Center of Excellence in Oral and Maxillofacial Biology, Department of Oral Biology and Diagnostic Sciences, Faculty of Dentistry, Chiang Mai University, Chiang Mai, 50200, Thailand. Electronic address:

Objective: This study aimed to investigate the efficacy of double antibiotics, including ciprofloxacin and metronidazole, in a new vehicle, hydroxypropyl methylcellulose (HPMC), against Enterococcus faecalis and Streptococcus gordonii grown in biofilm.

Design: Human mandibular premolars were prepared and divided into four groups: (i) negative control, (ii) positive control, (iii) infected with E. faecalis and S. Read More

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Computer Game Assisted Task Specific Exercises in the Treatment of Motor and Cognitive Function and Quality of Life in Stroke: A Randomized Control Study.

J Stroke Cerebrovasc Dis 2021 Jul 19;30(9):105991. Epub 2021 Jul 19.

Department of Physical and Rehabilitation Medicine, Baskent University Faculty of Medicine, Maresal Fevzi Cakmak Cad. 5. Sok. No: 48, Bahcelievler, Ankara, 06490, Turkey.

Objectives: Computer game assisted task specific exercises (CGATSE) are rehabilitation gaming systems (RGS) used in stroke rehabilitation to facilitate patient performance of high intensity, task based, repetitive exercises aiming to enhance neuroplasticity. CGATSE maybe an appealing option in home based rehabilitation of stroke patients, especially during the COVID-19 pandemic. This study aimed to determine the effects of CGATSE on hemiplegic arm-hand function, cognitive function and quality of life in stroke. Read More

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SARS-CoV-2 anti-spike antibody titres after vaccination with BNT162b2 in naïve and previously infected individuals.

J Infect Public Health 2021 Jul 17;14(8):1120-1122. Epub 2021 Jul 17.

Infectious Diseases Unit, Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy; Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy; Centre for Multidisciplinary Research in Health Science (MACH), University of Milan, Milan, Italy.

Great expectations are placed in vaccines against COVID-19 to control the pandemic. We reviewed the antibody titres in a cohort of healthcare workers (HCWs) vaccinated with BNT162b2 to assess the influence of a previous infection on them. We stratified the results according to the individual history of nasopharyngeal swab (NPS) and symptoms. Read More

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Kinetic, metabolic, and statistical analytics: addressing metabolic transport limitations among organelles and microbial communities.

Curr Opin Biotechnol 2021 Jul 19;71:91-97. Epub 2021 Jul 19.

Department of Chemical and Biomolecular Engineering, The Johns Hopkins University, 3400 North Charles Street, Baltimore, MD, 21218, USA.

Microbial organisms engage in a variety of metabolic interactions. A crucial part of these interactions is the exchange of molecules between different organelles, cells, and the environment. The main forces mediating this metabolic exchange are transporters. Read More

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Enhancing enzymatic performance with nanoparticle immobilization: improved analytical and control capability for synthetic biochemistry.

Curr Opin Biotechnol 2021 Jul 19;71:77-90. Epub 2021 Jul 19.

Center for Bio/Molecular Science and Engineering, Code 6900, U.S. Naval Research Laboratory, Washington, D.C., 20375, USA. Electronic address:

Enzymes are incredibly potent catalysts with the potential for rapid turnover rates and exquisite specificity, leading to their desired use in multiple biotechnological processes. Yet using these natural catalysts outside of their evolved role can necessitate significant engineering. Immobilization onto microscale (or larger) scaffolds can impart industrially-desired properties but often sacrifices enzymatic activity for long-term stability; in contrast, nanoparticle (NP) conjugation of enzymes can preserve or even enhance their activity. Read More

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Effect of Guo Qing Yi Tang combined with Western medicine cluster therapy on acute pancreatitis.

Am J Emerg Med 2021 Jul 8;50:66-70. Epub 2021 Jul 8.

Department of Critical Care Medicine, Jinjiang Hospital of Traditional Chinese Medicine, Jinjiang 362200, Fujian province, People's Republic of China.

Background: This study evaluated the effect of Guo Qing Yi Tang (GQYT) combined with Western medicine cluster therapy on acute pancreatitis (AP).

Methods: A total of 138 AP patients were recruited and divided into the observation group (68 patients) and control group (70 patients). The control group was treated with cluster therapy alone, while the observation group was treated with trans-jejunum feeding of GQYT combined with cluster therapy. Read More

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Proteome and transcriptome analysis revealed florfenicol via affected drug metabolism and lipid metabolism induce liver injury of broilers.

Poult Sci 2021 May 4;100(9):101228. Epub 2021 May 4.

College of Traditional Chinese Veterinary Medicine, Agriculture University of Hebei, Baoding, 071001, China; Hebei Veterinary Biotechnology Innovation Center, Baoding 071000, China.

In order to explore the mechanism of liver injury induced by florfenicol (FFC) in broilers. Sixty broilers were randomly divided into 2 groups: control group: normal drinking water and feed were given every d; FFC group: tap water containing FFC (0.15g/L) was given every d and feed was taken freely; each group was given 5 dd of continuous medication and feed was taken freely. Read More

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Aging microplastics in wastewater pipeline networks and treatment processes: Physicochemical characteristics and Cd adsorption.

Sci Total Environ 2021 Jul 8;797:148940. Epub 2021 Jul 8.

Centre for Green Technology, University of Technology Sydney, 15 Broadway, Sydney, NSW 2007, Australia.

Despite a wealth of information on removal of the microplastics (MPs) in wastewater treatment plants (WWTPs), little attention has been paid to how wastewater treatment process affect the MP physicochemical and adsorption characteristics. In this study, changes in physicochemical property of three MPs, i.e. Read More

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