20,669 results match your criteria contrast-enhanced magnetic


How tissue T1-variability influences DCE-MRI perfusion parameters estimation of recurrent high-grade glioma after surgery followed by radiochemotherapy.

Acta Radiol 2021 Aug 3:2841851211035911. Epub 2021 Aug 3.

Neuroradiology Unit, Azienda Ospedaliero-Universitaria of Parma, Parma, Italy.

Background: Quantification of dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) kinetic parameters (KPs) requires a determination of native tissue T1. Two approaches are adopted: (i) tissue T1-maps are acquired; and (ii) an a priori T1 value (fT1) is fixed for all patients (fT1-approach). Although it is more attractive, the fT1-approach might bias the results of KP calculations due to tissue T1 variability. Read More

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Can the delayed phase of quantitative contrast-enhanced mammography improve the diagnostic performance on breast masses?

Quant Imaging Med Surg 2021 Aug;11(8):3684-3697

Department of Ultrasonic Medicine, Nanfang Hospital, Southern Medical University, Guangzhou, China.

Background: Contrast-enhanced mammography (CEM) is an imaging tool for breast cancer detection. Most quantitative analyses of CEM involve two phases, and it is unknown whether an added delayed phase can improve its diagnostic performance compared to dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI). This study aimed to evaluate whether the delayed phase improves the diagnostic performance of CEM in distinguishing malignant and benign masses. Read More

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MR characteristics of mucinous tubular and spindle cell carcinoma (MTSCC) of the kidney: comparison with clear cell and papillary subtypes of renal cell carcinoma.

Abdom Radiol (NY) 2021 Aug 2. Epub 2021 Aug 2.

Department of Diagnostic Radiology, Mayo Clinic, 200 First St. SW, Rochester, MN, 55905, USA.

Purpose: To describe MR features of mucinous tubular spindle cell carcinoma (MTSCC) of the kidney that may help differentiate from clear cell renal cell carcinoma (ccRCC) and papillary RCC (pRCC).

Methods: 15 MTSCCs were retrospectively evaluated by MR with T2-weighted image without fat suppression (n = 15) and dynamic contrast-enhanced (DCE), fat-suppressed T1-weighted GRE (n = 11). Size-matched ccRCC (n = 30) and pRCC (n = 30) were evaluated as control. Read More

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Management of Neurocysticercosis in Children: Association of Child Neurology Consensus Guidelines.

Indian Pediatr 2021 Aug 2. Epub 2021 Aug 2.

Pediatric Neurology and Neurodevelopment, Medanta the Medicity, Gurugram, Haryana. Correspondence to: Prof Pratibha Singhi, Professor and Chief, Pediatric Neurology and Neurodevelopment, Medanta the Medicity, Gurugram, India.

Justification: Neurocysticercosis is a significant problem in India and other developing countries. but several aspects of this disease have no clear, practical guidelines. There is a need for, pragmatic guidelines, summarizing the available evidence, and filling in the gaps in evidence with expert advice to manage children with neurocysticercosis. Read More

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Guillain-Barré Syndrome After Acute Hepatitis E Infection: A Case Report and Literature Review.

Crit Care Nurse 2021 Aug;41(4):47-53

William D. Freeman is a professor of neurology and neurologic surgery and the founding and acting neuroscience intensive care unit Medical Director, Mayo Clinic, Jacksonville.

Introduction: Guillain-Barré syndrome precipitated by hepatitis E virus infection is rare, yet its incidence is increasing.

Clinical Findings: A 57-year-old man was transferred from another facility with fatigue, orange urine, and progressive weakness over 4 to 6 weeks. Initial laboratory results included total bilirubin, 9. Read More

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Fully automatic adaptive meshing based segmentation of the ventricular system for augmented reality visualization and navigation.

World Neurosurg 2021 Jul 29. Epub 2021 Jul 29.

Department of Neurosurgery, University Medical Center Utrecht, Utrecht, Province of Utrecht, The Netherlands; Department of Neurosurgery, University Hospital of Zürich, Zürich, Canton of Zürich, Switzerland.

Objective: Effective image segmentation of cerebral structures is fundamental to 3-D techniques such as augmented reality (AR). To be clinically viable, segmentation algorithms should be fully-automatic and easily integrated in existing digital infrastructure. We created a fully automatic adaptive-meshing-based segmentation system for T1-weighted magnetic resonance images (MRI) to automatically segment the complete ventricular system, running in a cloud-based environment that can be accessed on an AR device. Read More

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Hepatic actinomycosis after total pancreatectomy: A case report.

Int J Surg Case Rep 2021 Jul 20;85:106212. Epub 2021 Jul 20.

Department of Surgery, Kansai Medical University, Osaka, Japan.

Introduction And Importance: Hepatic actinomycosis (HA) is a rare infection mimicking a malignancy. HA after total pancreatectomy for a pancreatic tumor has not been reported.

Case Presentation: A 70-year-old woman with a history of gastrectomy and sigmoidectomy for benign lesions, underwent a total pancreatectomy for a non-invasive, intraductal papillary mucinous carcinoma (IPMC). Read More

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An in silico validation framework for quantitative DCE-MRI techniques based on a dynamic digital phantom.

Med Image Anal 2021 Jul 20;73:102186. Epub 2021 Jul 20.

Oden Institute for Computational Engineering and Sciences, The University of Texas at Austin, 201 E 24th St, Austin, TX 78712, United States; Livestrong Cancer Institutes, United States; Departments of Biomedical Engineering, United States; Departments of Diagnostic Medicine, United States; Departments of Oncology, The University of Texas at Austin, Austin, TX 78712, United States; Department of Imaging Physics, MD Anderson Cancer Center, Houston, TX 77030, United States.

Quantitative evaluation of an image processing method to perform as designed is central to both its utility and its ability to guide the data acquisition process. Unfortunately, these tasks can be quite challenging due to the difficulty of experimentally obtaining the "ground truth" data to which the output of a given processing method must be compared. One way to address this issue is via "digital phantoms", which are numerical models that provide known biophysical properties of a particular object of interest. Read More

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Omega-3 fatty acids are associated with blood-brain barrier integrity in a healthy aging population.

Brain Behav 2021 Jul 29. Epub 2021 Jul 29.

Department of Psychology, School of Behavioral Health, Loma Linda University, Loma Linda, California, USA.

In aging populations, omega-3 polyunsaturated fatty acids (PUFAs) have been associated with better cognitive function, slower rates of cognitive decline, and lower risk of developing dementia. Animal studies have shown that diets rich in omega-3 PUFAs reduce blood-brain barrier (BBB) disruption associated with aging, but this has yet to be observed in humans. Forty-five healthy subjects (mean age, 76 years) were recruited and underwent cognitive assessment (verbal learning and memory, language, processing speed, executive function, and motor control) and measurement of PUFAs. Read More

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Inter-reader agreement of the PI-QUAL score for prostate MRI quality in the NeuroSAFE PROOF trial.

Eur Radiol 2021 Jul 29. Epub 2021 Jul 29.

Department of Radiology, University College London Hospital NHS Foundation Trust, London, UK.

Objectives: The Prostate Imaging Quality (PI-QUAL) score assesses the quality of multiparametric MRI (mpMRI). A score of 1 means all sequences are below the minimum standard of diagnostic quality, 3 implies that the scan is of sufficient diagnostic quality, and 5 means that all three sequences are of optimal diagnostic quality. We investigated the inter-reader reproducibility of the PI-QUAL score in patients enrolled in the NeuroSAFE PROOF trial. Read More

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Ultrasound fusion biopsy.

Radiologe 2021 Jul 29. Epub 2021 Jul 29.

Department of Radiology, Interdisciplinary Ultrasound Center, Campus Charité Mitte, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Charitéplatz 1, 10117, Berlin, Germany.

Background: Ultrasound (US)-guided biopsy is widely used for the diagnostic confirmation of focal lesions. For sampling of prostate tissue, magnetic resonance imaging (MRI)/US fusion-guided biopsy has already been implemented in routine clinical practice and has shown a superior detection rate of significant prostate cancer in risk assessment compared with standard systematic biopsy. Newer three-dimensional software tools with volumetric mapping of the prostate and biopsy core channels provide a better overview of systematic biopsy and thus contribute to more accurate treatment planning. Read More

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Isolated Septic Arthritis of the Hip Due to Fusobacterium Nucleatum in An Immunocompetent Adult: A Case Report and Review of the Literature.

J Orthop Case Rep 2021 Apr;11(4):37-40

Department of Orthopaedic Surgery, Showa University School of Medicine, Hatanodai, Shinagawa-ku, Tokyo, Japan.

Introduction: Hip septic arthritis is more common in children than in adults. Staphylococcus aureus and Streptococcus spp. are commonly found in association with septic joints. Read More

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Treatment response of colorectal cancer liver metastases to neoadjuvant or conversion therapy: a prospective multicentre follow-up study using MRI, diffusion-weighted imaging and H-MR spectroscopy compared with histology (subgroup in the RAXO trial).

ESMO Open 2021 Jul 26;6(4):100208. Epub 2021 Jul 26.

Department of Transplantation and Liver Surgery, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.

Background: Colorectal cancer liver metastases respond to chemotherapy and targeted agents not only by shrinking, but also by morphologic and metabolic changes. The aim of this study was to evaluate the value of advanced magnetic resonance imaging (MRI) methods in predicting treatment response and survival.

Patients And Methods: We investigated contrast-enhanced MRI, apparent diffusion coefficient (ADC) in diffusion-weighted imaging and H-magnetic resonance spectroscopy (H-MRS) in detecting early morphologic and metabolic changes in borderline or resectable liver metastases, as a response to first-line neoadjuvant or conversion therapy in a prospective substudy of the RAXO trial (NCT01531621, EudraCT2011-003158-24). Read More

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Magnetic resonance radiomics features and prognosticators in different molecular subtypes of pediatric Medulloblastoma.

PLoS One 2021 29;16(7):e0255500. Epub 2021 Jul 29.

Department of Medical Imaging, Taipei Medical University Hospital, Taipei, Taiwan.

Purpose: Medulloblastoma (MB) is a highly malignant pediatric brain tumor. In the latest classification, medulloblastoma is divided into four distinct groups: wingless (WNT), sonic hedgehog (SHH), Group 3, and Group 4. We analyzed the magnetic resonance imaging radiomics features to find the imaging surrogates of the 4 molecular subgroups of MB. Read More

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Can Deep Learning Replace Gadolinium in Neuro-Oncology?: A Reader Study.

Invest Radiol 2021 Jul 28. Epub 2021 Jul 28.

From the Imaging Department, Gustave Roussy Cancer Campus, Université Paris-Saclay, Villejuif BioMaps (UMR1281), Université Paris-Saclay, CNRS, Inserm, CEA, Villejuif Guerbet Research, Villepinte Center for Visual Computing, CentraleSupélec, Inria, Université Paris-Saclay, Gif-sur-Yvette, France.

This study proposes and evaluates a deep learning method that predicts surrogate images for contrast-enhanced T1 from multiparametric magnetic resonance imaging (MRI) acquired using only a quarter of the standard 0.1 mmol/kg dose of gadolinium-based contrast agent. In particular, the predicted images are quantitatively evaluated in terms of lesion detection performance. Read More

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Role of multiparametric MRI in long-term surveillance following focal laser ablation of prostate cancer.

Br J Radiol 2021 Jul 29:20210414. Epub 2021 Jul 29.

Joint Department of Medical Imaging, University of Toronto, University Health Network - Mount Sinai Hospital - Women's College Hospital, Toronto, ON, Canada.

Objective: Determine the multiparametric magnetic resonance imaging (mpMRI) appearance of the prostate following focal laser ablation (FLA) for PCa and to identify imaging characteristics associated with recurrent disease.

Methods: Retrospective analysis of patients who underwent FLA for low-intermediate risk PCa between 2010 and 2014 was performed. Early (median 4 months) and late mpMRI (median 49 months) follow-up were qualitatively assessed for -weighted, dynamic contrast enhanced (DCE) and diffusion weighted imaging (DWI) appearances and also compared to corresponding PSA values and biopsy results. Read More

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Contrast-enhanced 3D-T2-weighted SPACE sequence for MRI detection and localization of adrenocorticotropin (ACTH) -secreting pituitary microadenomas.

Clin Endocrinol (Oxf) 2021 Jul 29. Epub 2021 Jul 29.

Department of Radiology, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China.

Objective: Cushing disease is a potentially fatal endocrine disorder caused by adrenocorticotropin (ACTH) -secreting microadenomas in the pituitary gland. Accurate detection and localization of the adenomas is the key to clinical treatment. This study analyzed the value of contrast-enhanced SPACE sequence in MRI assessment of ACTH-secreting pituitary microadenomas. Read More

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Magnetic resonance imaging findings of synovial sarcoma in children: location-dependent differences.

Pediatr Radiol 2021 Jul 28. Epub 2021 Jul 28.

Department of Radiology, Children's Hospital of Philadelphia, 3401 Civic Center Blvd., Philadelphia, PA, 19104, USA.

Background: While overall survival for children is greater than that for adults, synovial sarcoma remains an aggressive neoplasm with a potentially poor prognosis, and its magnetic resonance imaging (MRI) findings in children are not well described.

Objective: We aimed to characterize the spectrum of MRI findings of synovial sarcoma in children with respect to anatomical location and outcome.

Materials And Methods: Children with histologically confirmed synovial sarcoma and preoperative MRI performed within the past 11 years (2009-2020) were included. Read More

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Should fluorodeoxyglucose positron emission tomography/computed tomography be the first-line imaging investigation for restaging the laryngeal carcinoma patients?

World J Nucl Med 2021 Apr-Jun;20(2):164-171. Epub 2021 Feb 12.

Department of Medical Oncology, Mahatma Gandhi Medical College and Hospital, Jaipur, Rajasthan, India.

Posttreatment detection of residual/recurrence disease in the head and neck cancers is not an easy task. Treatment induces changes create difficulties in diagnosis on conventional imaging (computed tomography [CT], magnetic resonance imaging) as well as macroscopic inspection (direct laryngoscopy). Hence, we evaluate the diagnostic performance of contract-enhanced F-18 fluorodeoxyglucose positron emission tomography (FDG PET)/CT in restaging of laryngeal carcinoma Postchemotherapy-surgery and/or radiation therapy. Read More

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February 2021

Interfractional target changes in brain metastases during 13-fraction stereotactic radiotherapy.

Radiat Oncol 2021 Jul 28;16(1):140. Epub 2021 Jul 28.

Department of Radiation Oncology and Image-Applied Therapy, Kyoto University Graduate School of Medicine, 54 Shogoin Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan.

Background: The risk for radiation necrosis is lower in fractionated stereotactic radiotherapy (SRT) than in conventional radiotherapy, and 13-fraction SRT is our method of choice for the treatment of brain metastases ≥ around 2 cm or patients who are expected to have a good prognosis. As 13-fraction SRT lasts for at least 17 days, adaptive radiotherapy based on contrast-enhanced mid-treatment magnetic resonance imaging (MRI) is often necessary for patients undergoing 13-fraction SRT. In this study, we retrospectively analyzed interfractional target changes in patients with brain metastases treated with 13-fraction SRT. Read More

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Eosinophilic Myocarditis in a Patient With Infection.

JACC Case Rep 2021 Jun 16;3(6):954-959. Epub 2021 Jun 16.

First Department of Cardiology, National and Kapodistrian University of Athens Medical School, Hippocration General Hospital of Athens, Athens, Greece.

A 40-year-old woman with a pulmonary embolism, central nervous system infarcts, and eosinophilia was referred for evaluation. Findings on echocardiography and cardiac magnetic resonance were consistent with eosinophilic myocarditis with left ventricular involvement. Further examination led to the diagnosis of infection, and treatment with ivermectin and rivaroxaban resulted in clinical, laboratory, and cardiac imaging improvement. Read More

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A Rare Case of Severe Nontropical Isolated Right Ventricular Endomyocardial Fibrosis.

JACC Case Rep 2020 Nov 18;2(13):2078-2084. Epub 2020 Nov 18.

Heart Lung Institute, The Prince Charles Hospital, Chermside, Australia.

We present a case of late presentation nontropical endomyocardial fibrosis isolated to the right ventricle and tricuspid valve (TV). In response to deteriorating hemodynamics, surgical debulking and TV removal were performed before initiation of centralized venoarterial extracorporeal membrane oxygenation support. Definitive endomyocardial resection with a TV prosthesis was then successfully completed. Read More

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November 2020

Diffusion-Weighted Imaging: An Exciting and Problem-Solving Tool in Patients with Hepatic Metastases.

Indian J Radiol Imaging 2021 Jan 23;31(1):86-90. Epub 2021 May 23.

Department of Radiodiagnosis, Sher-i-Kashmir Institute of Medical Sciences, Srinagar, Jammu and Kashmir, India.

 The diffusion-weighted imaging (DWI) is based on the random Brownian motion of water molecules that influences image contrast depending on different pathological conditions.  The purpose of this study was to evaluate the efficacy of various magnetic resonance imaging (MRI) sequences including diffusion-weighted and gadobenate-enhanced MRI in the detection and characterization of liver lesions in a patient of known primary malignancy and to compare MRI with contrast-enhanced computed tomography (CECT) and ultrasonography (USG) in the detection of liver metastases.  All patients underwent a multiphase MRI. Read More

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January 2021

Multiparametric Magnetic Resonance Imaging in Evaluation of Clinically Significant Prostate Cancer.

Indian J Radiol Imaging 2021 Jan 23;31(1):65-77. Epub 2021 May 23.

Department of Imaging Sciences and Pathology, Saifee Hospital, Mumbai, Maharashtra, India.

 In this prospective study, we evaluate the role of multiparametric magnetic resonance imaging (mp-MRI) in the assessment of clinically significant prostate cancer at 1.5 T without endorectal coil (ERC).  Forty-five men with clinical suspicion of prostate cancer (prostate-specific antigen [PSA] level > 4 ng/mL, hard prostate on digital rectal examination, and suspicious area at transrectal ultrasound [TRUS]) were evaluated using the mp-MRI protocol over a period of 24 months. Read More

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January 2021

Quantitative Dynamic Contrast-Enhanced Magnetic Resonance Imaging for the Analysis of Microvascular Permeability in Peritumor Brain Edema of Fibrous Meningiomas.

Eur Neurol 2021 Jul 27;84(5):361-367. Epub 2021 Jul 27.

Department of Radiology, The Second Affiliated Hospital of Anhui Medical University, Hefei, China.

Introduction: This study aims to analyze the permeability of intra- and peri-meningiomas regions and compare the microvascular permeability between peritumoral brain edema (PTBE) and non-PTBE using DCE-MRI.

Methods: This was a retrospective of patients with meningioma who underwent surgery. The patients were grouped as PTBE and non-PTBE. Read More

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Automatic segmentation of brain metastases using T1 magnetic resonance and computed tomography images.

Phys Med Biol 2021 Jul 27. Epub 2021 Jul 27.

Memorial Sloan Kettering Cancer Center, New York, New York, UNITED STATES.

An increasing number of patients with multiple brain metastases are being treated with stereotactic radiosurgery (SRS). Manually identifying and contouring all metastatic lesions is difficult and time-consuming, and a potential source of variability. Hence, we developed a 3D deep learning approach for segmenting brain metastases on MR and CT images. Read More

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Classification of glioblastoma versus primary central nervous system lymphoma using convolutional neural networks.

Sci Rep 2021 Jul 26;11(1):15219. Epub 2021 Jul 26.

Department of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.

A subset of primary central nervous system lymphomas (PCNSL) are difficult to distinguish from glioblastoma multiforme (GBM) on magnetic resonance imaging (MRI). We developed a convolutional neural network (CNN) to distinguish these tumors on contrast-enhanced T-weighted images. Preoperative brain tumor MRIs were retrospectively collected among 320 patients with either GBM (n = 160) and PCNSL (n = 160) from two academic institutions. Read More

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FDG-PET predicts bone invasion and prognosis in patients with oral squamous cell carcinoma.

Sci Rep 2021 Jul 26;11(1):15153. Epub 2021 Jul 26.

School of Dentistry, China Medical University, Taichung, Taiwan.

F-fluorodeoxyglucose-positron emission tomography (FDG-PET) is widely used for tumor staging. This study sought to determine the relationship of preoperative primary tumor SUVmax (tSUVmax) with the clinicopathological features of patients with OSCC and to compare the prognostic ability of tSUVmax with that of other recurrence factors. Data of 340 patients with OSCC who were diagnosed, treated, and followed up at the Changhua Christian Hospital were retrospectively analyzed. Read More

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A Case of Multiple Sclerosing Pneumocytomas With Calcifications: Added Functional-based Information With Dynamic Contrast-enhanced Perfusion Magnetic Resonance Imaging.

J Thorac Imaging 2021 Jul 23. Epub 2021 Jul 23.

Departments of Radiology Diagnostic Pathology Respiratory Medicine Thoracic Surgery Center for Clinical Trial and Research Support Joint Research Laboratory of Advanced Medical Imaging, Fujita Health University School of Medicine, Toyoake, Aichi Prefecture, Japan.

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The Effect of Contrast Enhanced Abdominopelvic Magnetic Resonance Imaging on Expression and Methylation Level of and Genes.

Cell J 2021 Aug 17;23(3):335-340. Epub 2021 Jul 17.

Advanced Diagnostic and Interventional Radiology Research Center, Tehran University of Medical Sciences, Tehran, Iran.

Objective: To evaluate the effect of contrast enhanced abdominopelvic magnetic resonance imaging (MRI), using a 3 Tesla scanner, on expression and methylation level of and genes in human peripheral blood lymphocytes.

Materials And Methods: In this prospective study, blood samples were obtained from 20 volunteer patients with mean age of 43 ± 8 years (range 32-68 years) before contrast enhanced MRI, 2 hours and 24 hours after contrast enhanced abdominopelvic 3 Tesla MRI. After separation of mononuclear cells from peripheral blood, using Ficoll-Hypaque, we analyzed gene expression changes of and genes 2 hours and 24 hours after MRI using quantitative reverse transcription polymerase chain reaction (qRT-PCR). Read More

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