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A Review of COVID-19 Chilblains-like Lesions and Their Differential Diagnoses.

Adv Skin Wound Care 2021 Jul;34(7):348-354

General Purpose: To familiarize wound care practitioners with the differential diagnoses of chilblains-like lesions that could be associated with the complications of COVID-19.

Target Audience: This continuing education activity is intended for physicians, physician assistants, nurse practitioners, and nurses with an interest in skin and wound care.

Learning Objectives/outcomes: After participating in this educational activity, the participant will:1. Read More

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C.DOT - Convolutional Deep Object Tracker for Augmented Reality Based Purely on Synthetic Data.

IEEE Trans Vis Comput Graph 2021 Jun 14;PP. Epub 2021 Jun 14.

Augmented reality applications use object tracking to estimate the pose of a camera and to superimpose virtual content onto the observed object. Today, a number of tracking systems are available, ready to be used in industrial applications. However, such systems are hard to handle for a service maintenance engineer, due to obscure configuration procedures. Read More

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MacEmerg Podcast: A Novel Initiative to Connect a Distributed Community of Practice.

AEM Educ Train 2021 Jul 25;5(3):e10550. Epub 2020 Nov 25.

and the Royal College of Physicians and Surgeons of Canada Emergency Medicine Training Program McMaster University Burlington Ontario Canada.

Background: Regional knowledge dissemination and information sharing is a challenge among physically divided groups of physicians. Many staff and resident physicians do not have easy access to share clinical and medical education and research information with each other in an academic setting. Our divisions of emergency medicine could benefit from a novel approach aimed at improving overall connection and collaborative engagement. Read More

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Chinese Breast Milk Fat Composition and Its Associated Dietary Factors: A Pilot Study on Lactating Mothers in Beijing.

Front Nutr 2021 28;8:606950. Epub 2021 May 28.

Vanke School of Public Health, Tsinghua University, Beijing, China.

Regional differences were found in breast milk composition. This study intended to profile the composition of fatty acid (FA) and triacylglycerol (TAG) in Chinese breast milk and to explore its association with maternal diet. Breast milk samples and data of 52 lactating women at 60-90 days postpartum were collected. Read More

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Personal Doses of Cocaine and Coca Paste are Adulterated in Cartagena de Indias (Colombia).

ScientificWorldJournal 2021 25;2021:5562315. Epub 2021 May 25.

Grupo de Investigación en Innovación y Desarrollo Agropecuario y Agroindustrial (IDAA), Universidad de Cartagena, Campus Piedra de Bolívar, Cartagena de Indias 130015, Colombia.

Knowledge of drug composition consumed on the streets and the identification and quantification of their adulterants is essential for understanding unexpected side effects, tracking routes, and drug profiling. Therefore, this work aimed to determine the purity and to identify and quantify the main adulterants found in personal doses of cocaine (perico) and coca paste (bazuco) in Cartagena de Indias (Colombia). The data collected in this study describe a first attempt to introduce the qualitative and quantitative analyses of adulterants present in street drugs in Cartagena de Indias to improve surveillance. Read More

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Comparison of antioxidant and anti-inflammatory activity profiles of various chemically characterized Turkish propolis sub-types: Which propolis type is a promising source for pharmaceutical product development?

J Pharm Biomed Anal 2021 Jun 7;203:114196. Epub 2021 Jun 7.

Yeditepe University, Faculty of Pharmacy, Department of Pharmacognosy, Kayisdagi Cad., Atasehir, 34755, Istanbul, Turkey.

Propolis shows a great variation in its chemical content depending on the vegetation around the beehive. Determination of its botanical origin and the chemical characterization are the most important issues for the standardization and the quality evaluation for propolis samples that are intended to be used in the pharmaceutical industry. This study has focused on the identification of the botanical origin of 47 propolis samples collected from different locations in the Black Sea Region of Turkey. Read More

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Improving the experience of facility-based delivery for vulnerable women through obstetric care navigation: a qualitative evaluation.

BMC Pregnancy Childbirth 2021 Jun 11;21(1):425. Epub 2021 Jun 11.

Wuqu' Kawoq | Maya Health Alliance, 2da Avenida 3-48 Zona 3, Barrio Patacabaj, Tecpán, Chimaltenango, Guatemala.

Background: Global disparities in maternal mortality could be reduced by universal facility delivery. Yet, deficiencies in the quality of care prevent some mothers from seeking facility-based obstetric care. Obstetric care navigators (OCNs) are a new form of lay health workers that combine elements of continuous labor support and care navigation to promote obstetric referrals. Read More

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Approaching an undergraduate medical curriculum map: challenges and expectations.

BMC Med Educ 2021 Jun 10;21(1):341. Epub 2021 Jun 10.

University College London, London, UK.

Background: Feedback received from medical students at University College London Medical School (UCLMS) suggested a lack of clarity regarding the contents and subsequent assessment of the undergraduate curriculum. In order to address these issues, a specialist team was established with the aim of designing and implementing a Curriculum Map (CM), which have been recognised in their ability to provide a centralised, visual representation of the curriculum. While multiple perspectives from educators to stakeholders can be considered here, the need for the CM to remain student centred was identified as key at UCLMS. Read More

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Challenges towards serologic diagnostics of emerging arboviruses.

Clin Microbiol Infect 2021 Jun 7. Epub 2021 Jun 7.

Institute of Virology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany; Martsinovsky Institute of Medical Parasitology, Tropical and Vector-Borne Diseases, Sechenov University, Moscow, Russia; German Centre for Infection Research (DZIF), Associated Partner Charité-Universitätsmedizin Berlin, Berlin, Germany. Electronic address:

Background: Appropriate laboratory diagnostics for emerging arboviruses are key for patient management, surveillance, and intervention, including molecular tests and serologic tests detecting viral antigen or virus-specific antibodies.

Objectives: We provide an overview of the challenges towards serologic testing for the most important emerging arboviruses, including Zika (ZIKV), dengue (DENV), and chikungunya virus (CHIKV).

Sources: We retrieved a dataset on performance of commercially available antibody- and antigen-detecting tests from 89 peer-reviewed articles conducting a systematic literature research in PubMed. Read More

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Development and content validity of the Barth Syndrome Symptom Assessment (BTHS-SA) for adolescents and adults.

Orphanet J Rare Dis 2021 Jun 9;16(1):264. Epub 2021 Jun 9.

Adelphi Values, 290 Congress St, 6th Floor, Boston, MA, USA.

Background: Barth Syndrome (BTHS) is a rare genetic disorder that presents as a complex of debilitating symptoms and reduced life expectancy. Well-developed, BTHS-specific assessments measuring primary signs and symptoms of BTHS are not currently available, making it difficult to evaluate treatment effects in BTHS clinical studies. The objective of this research was to develop symptom-focused patient-reported outcome (PRO) measures for use in clinical studies with adolescents and adults with BTHS. Read More

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A non-pharmacological approach to the treatment of urinary tract infections: case reports with Utipro Plus.

Drugs Context 2021 24;10. Epub 2021 May 24.

Clinic Saint Jean, Brussels, Belgium.

Recurrent urinary tract infections (UTIs) can profoundly impair patients' quality of life and carry a substantial health resource burden. Although antibiotics are the mainstay of treatment, interest is growing in identifying antibiotic-sparing alternatives. Utipro Plus is a medical device that acts as a mechanical barrier to protect the intestinal lumen against the adherence and invasion of uropathogenic strains of . Read More

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Identifying behavioral types of dietary lapse from a mobile weight loss program: Preliminary investigation from a secondary data analysis.

Appetite 2021 Jun 10;166:105440. Epub 2021 Jun 10.

Department of Psychology, College of Arts and Sciences, Drexel University, United States; Center for Weight, Eating, And Lifestyle Sciences (WELL Center), Drexel University, United States.

Success in behavioral weight loss (BWL) programs depends on adherence to the recommended diet to reduce caloric intake. Dietary lapses (i.e. Read More

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Nutrient Composition of a Selection of Plant-Based Ground Beef Alternative Products Available in the United States.

J Acad Nutr Diet 2021 Jun 2. Epub 2021 Jun 2.

Background: Sales of plant-based foods intended as direct replacements for animal products have been growing in the United States. Little is known about the nutritional quality of these products.

Objective: Our aim was to evaluate the nutritional quality of a selection of plant-based ground beef alternative products available in the US marketplace and compare it with the nutrient content of ground beef. Read More

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Mixed methods process evaluation of my breathing matters, a digital intervention to support self-management of asthma.

NPJ Prim Care Respir Med 2021 Jun 4;31(1):35. Epub 2021 Jun 4.

Centre for Clinical and Community Applications of Health Psychology, School of Psychology, Faculty of Environmental and Life Sciences, University of Southampton, Southampton, UK.

This study aimed to explore user engagement with 'My Breathing Matters', a digital self-management intervention for asthma, and identify factors that may influence engagement. In a mixed methods design, adults with asthma allocated to the intervention arm of a feasibility trial (n = 44) participated in semi-structured interviews (n = 18) and a satisfaction questionnaire (n = 36) to explore their views and experiences of the intervention. Usage data highlighted that key intervention content was delivered to most users. Read More

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Exploring medical ethics' implementation challenges: A qualitative study.

J Educ Health Promot 2021 27;10:66. Epub 2021 Feb 27.

Endocrinology and Metabolism Research Center, Medical Ethics and History of Medicine Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.

Background: Adherence to medical ethics principles by medical professionals is required to improve health-care system's quality. Recognizing medical ethics' challenges and attempting to resolve them are important in the implementation of medical ethics in practice. This study aimed to explore such challenges at Iran's medical sciences universities in 2018. Read More

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February 2021

#BoomerRemover: COVID-19, ageism, and the intergenerational twitter response.

J Aging Stud 2021 Jun 30;57:100929. Epub 2021 Mar 30.

Assistant Professor of Sociology, Winston-Salem State University, Department of Behavioral Sciences, 601 S. Martin Luther King Jr. Dr., Winston-Salem, NC 27110, United States of America. Electronic address:

Early reports of COVID-19 often inaccurately presented the virus as a serious concern only among older adults. On the social media platform of Twitter, #BoomerRemover originated as a hashtag intended to express the age-related disparities of COVID-19. This study used a content analysis to examine tweets over a two-week period in March 2020 that used #BoomerRemover to discuss COVID-19 among older adults. Read More

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Nudge me: tailoring text messages for prescription adherence through N-of-1 interviews.

Transl Behav Med 2021 Jun 3. Epub 2021 Jun 3.

University of Colorado Anschutz Medical Campus, Aurora, CO, USA.

Almost 50% of patients with cardiovascular diseases face challenges in taking medications and increased morbidity and mortality. Text messaging may impact medication refill behavior and can be delivered at scale to patients by texting mobile phones. To obtain feedback from persons with chronic conditions on the design of interactive text messages and determine language of message for making messages that can motivate patients to refill medications on time. Read More

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Adolescents' Exposure to Online Risks: Gender Disparities and Vulnerabilities Related to Online Behaviors.

Int J Environ Res Public Health 2021 May 27;18(11). Epub 2021 May 27.

Center for Terrorism and Security Studies, University of Massachusetts Lowell, Lowell, MA 01854, USA.

In the last decade, readily available electronic devices have created unprecedented opportunities for teens to access a wide variety of information and media-both positive and negative-on the internet. Despite the increasing number of initiatives taking place worldwide intended to assess and mitigate the online risks encountered by children and adolescents, there is still a need for a better understanding of how adolescents use the internet and their susceptibility to exposure to risks in the online space. We conducted a cross-sectional online survey of a convenience sample of 733 8th and 9th grade students in Utah. Read More

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Microstructure and Abrasive Wear Resistance of Metal Matrix Composite Coatings Deposited on Steel Grade AISI 4715 by Powder Plasma Transferred Arc Welding Part 2. Mechanical and Structural Properties of a Nickel-Based Alloy Surface Layer Reinforced with Particles of Tungsten Carbide and Synthetic Metal-Diamond Composite.

Materials (Basel) 2021 May 25;14(11). Epub 2021 May 25.

Welding Department, Faculty of Mechanical Engineering, Silesian University of Technology, Konarskiego 18A, 44-100 Gliwice, Poland.

The article is the continuation of a cycle of works published in a Special Issue of MDPI entitled "Innovative Technologies and Materials for the Production of Mechanical, Thermal and Corrosion Wear-Resistant Surface Layers and Coatings" related to tests concerning the microstructure and mechanical properties of innovative surface layers made using the Powder Plasma Transferred Arc Welding (PPTAW) method and intended for work surfaces of drilling tools and machinery applied in the extraction industry. A layer subjected to tests was a metal matrix composite, made using powder based on a nickel alloy containing spherical fused tungsten carbide (SFTC) particles, which are fused tungsten carbide (FTC) particles and spherical particles of tungsten-coated synthetic metal-diamond composite (PD-W). The layer was deposited on the substrate of low-alloy structural steel grade AISI 4715. Read More

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Apple Pomace as a Source of Bioactive Polyphenol Compounds in Gluten-Free Breads.

Antioxidants (Basel) 2021 May 19;10(5). Epub 2021 May 19.

Department of Carbohydrate Technology and Cereal Processing, Faculty of Food Technology, University of Agriculture in Krakow, Balicka 122 Street, 30-149 Krakow, Poland.

Gluten-free products based on starch and hydrocolloids are deficient in nutrients and do not contain pro-health substances. Therefore, they should be enriched in raw materials naturally rich in antioxidants, especially if they are intended for celiac patients, prone to high oxidative stress. Apart from the traditionally used pseudo-cereals, seeds, vegetables and fruits, innovative substrates such as the by-product (especially in Poland) dry apple pomace could be applied. Read More

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Influence of a Rejuvenator on Homogenization of an Asphalt Mixture with Increased Content of Reclaimed Asphalt Pavement in Lowered Technological Temperatures.

Materials (Basel) 2021 May 14;14(10). Epub 2021 May 14.

Faculty of Civil Engineering and Architecture, Opole University of Technology, 45-061 Opole, Poland.

The most technologically advanced form of road construction uses a high content of reclaimed asphalt pavement (RAP) as a component of its asphalt mixture (AM). However, there is a real problem with the effective interaction of RAP and MA. The research herein described presents an effective use of RAP originating from the recycling process of old pavements thanks to the application of an original rejuvenator. Read More

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Properties of WCCo Composites Produced by the SPS Method Intended for Cutting Tools for Machining of Wood-Based Materials.

Materials (Basel) 2021 May 17;14(10). Epub 2021 May 17.

Department of Mechanical Processing of Wood, Institute of Wood Sciences and Furniture, Warsaw University of Life Sciences, Nowoursynowska Street, 166, 02-787 Warsaw, Poland.

This paper presents the possibility of using the Spark Plasma Sintering (SPS) method to obtain WCCo composite materials. Such materials are used as cutting blades for machining wood-based materials. Two series of composites, different in grain size and cobalt content, were analyzed in the paper. Read More

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A Pilot Study of a Parent-Mediated, Web-Based Motor Skill Intervention for Children With Down Syndrome: Project SKIP.

Adapt Phys Activ Q 2021 May 31:1-22. Epub 2021 May 31.

University of South Carolina.

To inform the development of scalable and sustainable fundamental motor skill interventions for children with Down syndrome, this study examined the feasibility and preliminary effectiveness of Project Skill Intervention Implemented by Parents (Project SKIP), a web-based, parent-mediated intervention intended to improve ball skills among children with Down syndrome. Twenty-four families enrolled in the study (including 13 boys and 11 girls; Mage = 4.92). Read More

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Optimizing hormone extraction protocols for whale baleen: Tackling questions of solvent:sample ratio and variation.

Gen Comp Endocrinol 2021 May 29:113828. Epub 2021 May 29.

Department of Biological Sciences, Northern Arizona University, 617 S. Beaver St., PO Box 5640, Flagstaff, AZ 86011, USA.

Obtaining endocrine data from alternative sample types such as baleen and other keratinized tissues has proven a valuable tool to investigate reproductive and stress physiology via steroid hormone quantification, and metabolic stress via thyroid hormone quantification in whales and other vertebrates. These alternative sample types provide an integrated measure of plasma levels over the period that the structure was growing, thus capturing months or even years of an individual's endocrine history. Additionally, their robust and stable keratin matrix allows such samples to be stored for years to decades, enabling the analysis and comparison of endocrine patterns from past and modern populations. Read More

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Writing for publication: Structure, form, content, and journal selection.

J Perioper Pract 2021 Jun;31(6):230-233

University of Cambridge Medical Library, Cambridge, UK.

This article provides an overview of writing for publication in peer-reviewed journals. While the main focus is on writing a research article, it also provides guidance on factors influencing journal selection, including journal scope, intended audience for the findings, open access requirements, and journal citation metrics. Finally, it covers the standard content of a scientific journal article, providing general advice and guidance regarding the information researchers would typically include in their published papers. Read More

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Narrative review of clinical practice guidelines for treating people with moderate or severe traumatic brain injury.

NeuroRehabilitation 2021 May 21. Epub 2021 May 21.

American Institute for Research, Arlington, VA, USA.

Background: Practice guidelines (CPGs) provide informed treatment recommendations from systematic reviews and assessment of the benefits and harms that are intended to optimize patient care. Review of CPGs addressing rehabilitation for people with moderate/severe traumatic brain injury (TBI), has not been fully investigated.

Objective: Identify published, vetted, clinical practice guidelines that address rehabilitation for people with moderate/severe TBI. Read More

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Communication as teaching content of veterinary studies - a joint position paper from the DVG specialist group "communication and didactics" and the GMA veterinary medicine committee.

GMS J Med Educ 2021 15;38(4):Doc84. Epub 2021 Apr 15.

University of Witten/Herdecke, Faculty of Health, Chair of Didactics and Educational Research in Health Care, Witten, Germany.

Veterinarians have to face many communicative challenges in their professional capacity. Successful professional communication increases satisfaction among pet owners, staff members and colleagues, and ultimately also the veterinarians' own satisfaction. On the other hand, unsuccessful communication can easily lead to rejection, distrust and dissatisfaction. Read More

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Description and comparison of exam wrapper learning strategy use in baccalaureate and associate degree nursing students: A descriptive study.

Nurse Educ Today 2021 Aug 17;103:104961. Epub 2021 May 17.

Adult Nursing Department, University of Massachusetts Dartmouth, 285 Old Westport Rd. North Dartmouth, MA 02747, United States of America.

Background: Exam wrapper, a structured self-regulated learning strategy, assists students to review study habits and performance on an exam with the goal of improving future study habits. Little is known about the use of this strategy in nursing students, particularly associate degree students.

Objectives: To describe and compare demographic characteristics, study habits, reasons for getting content wrong on an exam and future study plans between associate degree and baccalaureate nursing students. Read More

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Understanding good leadership in the context of English care home inspection reports.

Leadersh Health Serv (Bradf Engl) 2021 May;ahead-of-print(ahead-of-print)

Suffolk Business School, University of Suffolk, Ipswich, UK.

Purpose: As part of their inspection of care homes in England, the statutory inspector (the Care Quality Commission [CQC]) makes a judgement on the quality of the home's leadership. Their view is critical as it is intended to inform consumer choice and because the statutory nature of inspection means these views hold considerable authority. The purpose of this paper is to look at the content of a selection of reports and seek to determine what the CQC understands by the concept of "good leadership". Read More

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Influence of low tumor content on tumor mutational burden estimation by whole-exome sequencing and targeted panel sequencing.

Clin Transl Med 2021 May;11(5):e415

Department of In Vitro Diagnostic Reagent, National Institutes for Food And Drug Control (NIFDC), Beijing, China.

Background: Tumor mutational burden (TMB) is a promising biomarker for stratifying patient subpopulation who would benefit from immune checkpoint blockade (ICB) therapies. Although great efforts have been made for standardizing TMB measurement, mutation calling and TMB quantification can be challenging in samples with low tumor content including liquid biopsies. The effect of varying tumor content on TMB estimation by different assay methods has never been systematically investigated. Read More

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