Clin Microbiol Infect 2021 Jun 7. Epub 2021 Jun 7.
Institute of Virology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany; Martsinovsky Institute of Medical Parasitology, Tropical and Vector-Borne Diseases, Sechenov University, Moscow, Russia; German Centre for Infection Research (DZIF), Associated Partner Charité-Universitätsmedizin Berlin, Berlin, Germany. Electronic address:
Background: Appropriate laboratory diagnostics for emerging arboviruses are key for patient management, surveillance, and intervention, including molecular tests and serologic tests detecting viral antigen or virus-specific antibodies.
Objectives: We provide an overview of the challenges towards serologic testing for the most important emerging arboviruses, including Zika (ZIKV), dengue (DENV), and chikungunya virus (CHIKV).
Sources: We retrieved a dataset on performance of commercially available antibody- and antigen-detecting tests from 89 peer-reviewed articles conducting a systematic literature research in PubMed. Read More