1,221,246 results match your criteria consumption


A new mechanism of POCD caused by sevoflurane in mice: cognitive impairment induced by cross-dysfunction of iron and glucose metabolism.

Aging (Albany NY) 2021 Sep 21;13(undefined). Epub 2021 Sep 21.

Laboratory of Molecular Iron Metabolism, College of Life Science, Hebei Normal University, Shijiazhuang 050024, Hebei Province, China.

Sevoflurane (Sev) is a commonly used anesthetic in hospitals that can cause neurotoxicity. Postoperative cognitive dysfunction (POCD) is a common clinical problem induced by some anesthetics. However, the exact mechanism of neurotoxicity induced by Sev is unclear. Read More

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September 2021

When in America, do as the Americans? The evolution of health behaviors and outcomes across immigrant cohorts.

Econ Hum Biol 2021 Sep 14;43:101063. Epub 2021 Sep 14.

Department of Economics, Illinois Wesleyan University, 1402 Park Street, SFH 320, Bloomington, IL 61702, USA. Electronic address:

This study seeks to understand US immigrants' health-related behaviors and outcomes across arrival cohorts. We simultaneously examine risky consumption choices (smoking and drinking) and physical health conditions (asthma, diabetes, vision problems, and coronary heart diseases) using data from the National Health Interview Surveys (1989-2018). We incorporate cohort fixed-effects and the interactions between cohort effects and years since immigration into our empirical framework to capture the dynamics of immigrant health over time. Read More

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September 2021

Effect of methionine chelated Zn and Mn and corn particle size on Large White male turkey live performance and carcass yields.

Poult Sci 2021 Aug 20;100(11):101444. Epub 2021 Aug 20.

Prestage Department of Poultry Science, North Carolina State University, Raleigh, NC 27695-7608, USA. Electronic address:

Most turkey research has been conducted with a regular corn particle size set through phase-feeding programs. This study's first objective was to determine the effect of increasing corn particle size through the feed phases on performance, processing yield, and feed milling energy usage in Large White commercial male turkey production. Zinc (Zn) and manganese (Mn) are essential microminerals for animals' healthy growth. Read More

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Association between perioperative intravenous lidocaine and subjective quality of recovery: A meta-analysis of randomized controlled trials.

J Clin Anesth 2021 Sep 18;75:110521. Epub 2021 Sep 18.

Department of Emergency Medicine, E-Da Hospital, Kaohsiung city, Taiwan; College of Medicine, I-Shou University, Kaohsiun cityg, Taiwan. Electronic address:

Study Objective: To evaluate the impact of perioperative intravenous lidocaine on the quality of recovery (QoR) following surgery.

Design: Meta-analysis of randomized controlled trials (RCTs).

Setting: Postoperative care. Read More

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September 2021

Effects of different Danish food consumption patterns on Water ScarcityFootprint.

J Environ Manage 2021 Sep 18;300:113713. Epub 2021 Sep 18.

Research Group on EcoIndustrial System Analysis, Department of Environmental Science, Aarhus University, Frederiksborgvej 399, Postboks 358, DK-4000, Roskilde, Denmark; Aarhus University Centre for Circular Bioeconomy, Denmark; European Commission, Joint Research Centre, Directorate Growth and Innovation, Circular Economy and Industrial Leadership Unit, Seville, Spain.

Food production and consumption have been recognized as a major source of environmental impacts. To ensure food security and a sustainable food system, dietary changes have been identified as one of the valuable strategies to reduce impacts on the environment while promoting human health. The vast majority of scientific literature has been focused on the effects of food consumption on climate change while neglecting to assess the degree of water scarcity impacts due to water consumption embodied in food. Read More

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September 2021

Fungal endophthalmitis: Analysis of 730 consecutive eyes from seven tertiary eye care centers in India.

Ophthalmol Retina 2021 Sep 18. Epub 2021 Sep 18.

Department of Retina and Vitreous, Aravind Eye Hospital, Madurai, India.

Purpose: To evaluate the clinical and microbiological features of a large cohort of culture-confirmed fungal endophthalmitis across India.

Design: Cross-sectional hospital-based retrospective medical records review.

Participants: Seven large tertiary eye care centers from different regions of India. Read More

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September 2021

Effect of Ketamine on Binge Drinking Patterns in Crossed Alcohol-Preferring (cHAP) Mice.

Alcohol 2021 Sep 18. Epub 2021 Sep 18.

Addiction Neuroscience, Department of Psychology and Indiana Alcohol Research Center, Indiana University-Purdue University Indianapolis, Indianapolis, Indiana, 46202.

Background: Previous research has demonstrated the utility of subanesthetic doses of ketamine in decreasing binge (Drinking-in-the-Dark, or DID) 20% alcohol intake in female inbred (C57BL/6J) mice when administered 12 hours prior to alcohol access (Crowley et al., 2019). In the current study, we assess the efficacy of a similar ketamine pretreatment using male and female selectively bred, crossed High Alcohol Preferring (cHAP) mice, which also drink to intoxication, but are not inbred. Read More

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September 2021

Exercise training for prevention and treatment of older adults with heart failure with preserved ejection fraction.

Exp Gerontol 2021 Sep 18:111559. Epub 2021 Sep 18.

Cardiovascular Medicine Section, Department of Internal Medicine, Wake Forest School of Medicine, Winston Salem, USA. Electronic address:

Heart failure (HF) with preserved ejection fraction (HFpEF) is the most rapidly increasing form of HF, occurs primarily in older women, and is associated with high rates of morbidity, mortality, and health care expenditures. In the highest age decile (≥90 years old), nearly all patients with HFpEF. As our understanding of the disease has grown in the last few years, we now know that HFpEF is a systemic disorder influenced by aging processes. Read More

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September 2021

Innovative Drying Technologies for Biopharmaceuticals.

Int J Pharm 2021 Sep 18:121115. Epub 2021 Sep 18.

Pharmaceutical and Molecular Biotechnology Research Centre (PMBRC), Waterford Institute of Technology, Main Campus, Cork Road, Waterford, Ireland, X91K0EK.

In the past two decades, biopharmaceuticals have been a breakthrough in improving the quality of lives of patients with various cancers, autoimmune, genetic disorders etc. With the growing demand of biopharmaceuticals, the need for reducing manufacturing costs is essential without compromising on the safety, quality, and efficacy of products. Batch Freeze-drying is the primary commercial means of manufacturing solid biopharmaceuticals. Read More

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September 2021

Sleep, psychiatric and socioeconomic factors associated with substance use in a large population sample: A cross-sectional study.

Pharmacol Biochem Behav 2021 Sep 18:173274. Epub 2021 Sep 18.

Departamento de Psicobiologia, Universidade Federal de São Paulo, Rua Napoleão de Barros, 925, São Paulo 04024-002, Brazil.

Multiple elements modulate drug use, including sleep, which is increasingly being considered as an important contributor to substance use and abuse. The present study aimed to evaluate the association between sleep, psychiatric and socioeconomic/demographic factors and substance use in a large-scale representative sample from the city of São Paulo, Brazil. Data from the 2007 São Paulo Epidemiological Sleep Study (EPISONO) database were used. Read More

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September 2021

Switching up sides: Using choice architecture to alter children's menus in restaurants.

Appetite 2021 Sep 18:105704. Epub 2021 Sep 18.

Department of Food Science and Human Nutrition, Colorado State University, 1571 Campus Delivery, Fort Collins, CO, 80523, USA; Division of Nutritional Sciences, Cornell University, 3107 Marth Van Rensselaer Hall, Ithaca, NY, 14853, USA. Electronic address:

U.S. children's frequent consumption of restaurant foods has been associated with low vegetable consumption. Read More

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September 2021

Activation of locus coeruleus to rostromedial tegmental nucleus (RMTg) noradrenergic pathway blunts binge-like ethanol drinking and induces aversive responses in mice.

Neuropharmacology 2021 Sep 18:108797. Epub 2021 Sep 18.

Department of Psychology and Neuroscience, University of North Carolina at Chapel Hill, NC, 27599-3270, USA; Bowles Center for Alcohol Studies, University of North Carolina at Chapel Hill, School of Medicine, NC, 27599-7178, USA. Electronic address:

There is strong evidence that ethanol entails aversive effects that can act as a deterrent to overconsumption. We have found that in doses that support the development of a conditioned taste aversion ethanol increases the activity of tyrosine hydroxylase (TH) positive neurons in the locus coeruleus (LC), a primary source of norepinephrine (NE). Using cre-inducible AAV5-ChR2 viruses in TH-ires-cre mice we found that the LC provides NE projections that innervate the rostromedial tegmental nucleus (RMTg), a brain region that has been implicated in the aversive properties of drugs. Read More

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September 2021

Visual cues associated with sweet taste increase short-term eating and grab attention in healthy volunteers.

Physiol Behav 2021 Sep 18:113600. Epub 2021 Sep 18.

School of Psychology and Sussex Neuroscience, University of Sussex, Brighton, BN1 9QH.

Most studies that examine responses to food cues use images of actual foods as stimuli. Since foods are rewarding in multiple ways, it then becomes difficult to try and partial out the role of the importance of different aspects of food reward. Here we aimed to evaluate the impact of novel visual cues specifically associated with the immediate sensory reward from a liked sweet taste. Read More

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September 2021

Do Medical Insurance Companies Reimburse Telemedicine Office Visits the Same as In-Person Office Visits in an Academic Oral and Maxillofacial Surgeon Setting?

J Oral Maxillofac Surg 2021 Aug 16. Epub 2021 Aug 16.

Assistant Professor and Section Chief of Oral and Maxillofacial Surgery, Philadelphia Veterans Affairs Medical Center, Penn Presbyterian Medical Center, University of Pennsylvania School of Dental Medicine, Philadelphia, PA. Electronic address:

Purpose: Telemedicine use has grown exponentially during the last decade but a barrier to widespread adoption remains reimbursement rates for providers. The aim of this study is to compare reimbursement rates of telemedicine and in-person visits in an academic oral and maxillofacial surgery practice.

Methods: The investigators implemented a retrospective cohort study. Read More

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The number of response categories in ordered response models.

Int J Biostat 2021 Sep 21. Epub 2021 Sep 21.

Department of Political Sciences, University of Naples Federico II, Napoli, Italy.

The choice of the number of response categories is a crucial issue in categorization of a continuous response. The paper exploits the Proportional Odds Models' property which allows to generate ordinal responses with a different number of categories from the same underlying variable. It investigates the asymptotic efficiency of the estimators of the regression coefficients and the accuracy of the derived inferential procedures when varies. Read More

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September 2021

Global sales and operations planning: A multinational manufacturing company perspective.

PLoS One 2021 21;16(9):e0257572. Epub 2021 Sep 21.

Chair for Information Systems and Supply Chain Management, Westfälische Wilhelms-Universität Münster, Münster, Germany.

The purpose of this paper is to analyse the global Sales and Operations Planning (S&OP) process and investigate the steps to support consolidated business planning in worldwide operations and large-scale supply chains. The paper conducts a case study at a multinational manufacturing company applying an abductive approach. It combines the deductive logic from theory and the inductive logic from field observation in an attempt to elaborate further on theory on global S&OP. Read More

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September 2021

The impact of green credit on economic growth-The mediating effect of environment on labor supply.

PLoS One 2021 21;16(9):e0257612. Epub 2021 Sep 21.

School of Economics and Management, Shanghai Ocean University, Shanghai, China.

Background: The progress of green credit in China is accelerating, but its development is uneven and insufficient in different regions. And whether the issuance of green credit can effectively promote the improvement of the environment and economy is not well understood.

Objective: Previous research has found that green credit promotes economic growth through improvement of the industrial structure and green technological innovation. Read More

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September 2021

Prevalence and factors associated with family planning during COVID-19 pandemic in Bangladesh: A cross-sectional study.

PLoS One 2021 21;16(9):e0257634. Epub 2021 Sep 21.

Department of Neuroscience, University of Minnesota, Minneapolis, MN, United States of America.

Background And Objectives: The COVID-19 pandemic has negatively impacted health systems worldwide, including in Bangladesh, limiting access to family planning information (FP) and services. Unfortunately, the evidence on the factors linked to such disruption is limited, and no study has addressed the link among Bangladeshis. This study aimed to examine the socioeconomic, demographic, and other critical factors linked to the use of FP in the studied areas during the COVID-19 pandemic. Read More

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September 2021

Twenty years of gender equality research: A scoping review based on a new semantic indicatorr.

PLoS One 2021 21;16(9):e0256474. Epub 2021 Sep 21.

Faculty of Economics and Management, Centre for Family Business Management, Free University of Bozen-Bolzano, Bozen-Bolzano, Italy.

Gender equality is a major problem that places women at a disadvantage thereby stymieing economic growth and societal advancement. In the last two decades, extensive research has been conducted on gender related issues, studying both their antecedents and consequences. However, existing literature reviews fail to provide a comprehensive and clear picture of what has been studied so far, which could guide scholars in their future research. Read More

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September 2021

Total mercury concentrations in invasive lionfish (Pterois volitans/miles) from the Atlantic coast of Florida.

PLoS One 2021 21;16(9):e0234534. Epub 2021 Sep 21.

Department of Biology, University of North Florida, Jacksonville, FL, United States of America.

Invasive lionfish (Pterois volitans/miles) pose a serious threat to marine ecosystems throughout the western Atlantic Ocean and Caribbean Sea. The development of a fishery for lionfish has been proposed as a strategy for controlling populations; however, there is concern about consumption of this species by humans due to its high trophic position and potential for bioaccumulation of mercury. We analyzed total mercury (THg) in tissues of lionfish from two locations on the east coast of Florida. Read More

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September 2021

Study on the effect of digital economy on high-quality economic development in China.

PLoS One 2021 21;16(9):e0257365. Epub 2021 Sep 21.

School of Economics and Management, Chongqing University of Posts and Telecommunications, Chongqing, China.

At present, the digital economy, which takes information technology and data as the key elements, is booming and has become an important force in promoting the economic growth of various countries. In order to explore the current dynamic trend of China's digital economy development and the impact of the digital economy on the high-quality economic development, this paper measures the digital economic development index of 30 cities in China from the three dimensions of digital infrastructure, digital industry, and digital integration, uses panel data of 30 cities in China from 2015 to 2019 to construct an econometric model for empirical analysis, and verifies the mediating effect of technological progress between the digital economy and high-quality economic development. The results show that (1) The development level of China's digital economy is increasing year by year, that the growth of digital infrastructure is obvious, and that the development of the digital industry is relatively slow. Read More

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September 2021

Nerve Blocks for Postoperative Pain Management in Children Receiving Subcutaneous Implantable Cardioverter-Defibrillators: A Case Series.

A A Pract 2021 Sep 17;15(9):e01520. Epub 2021 Sep 17.

From the Departments of Anesthesiology.

Subcutaneous implantable cardioverter-defibrillator (S-ICD) placement may cause significant postoperative pain. Limited research exists on regional anesthesia for pediatric S-ICD placement. This case series examined transversus thoracic plane blocks (TTPBs), pectointercostal fascial plane blocks (PIFBs), pectoralis nerve I and II blocks, paravertebral, serratus anterior plane, and erector spinae plane blocks (ESPBs) in 10 children receiving S-ICDs. Read More

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September 2021

The "Outcome Reporting in Brief Intervention Trials: Alcohol" (ORBITAL) Core Outcome Set: International Consensus on Outcomes to Measure in Efficacy and Effectiveness Trials of Alcohol Brief Interventions.

J Stud Alcohol Drugs 2021 Sep;82(5):638-646

School of Social Sciences, Humanities and Law, Teesside University, Middlesbrough, United Kingdom.

Objective: The purpose of this study was to report the "Outcome Reporting in Brief Intervention Trials: Alcohol" (ORBITAL) recommended core outcome set (COS) to improve efficacy and effectiveness trials/evaluations for alcohol brief interventions (ABIs).

Method: A systematic review identified 2,641 outcomes in 401 ABI articles measured by 1,560 different approaches. These outcomes were classified into outcome categories, and 150 participants from 19 countries participated in a two-round e-Delphi outcome prioritization exercise. Read More

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September 2021

#Alcohol: Portrayals of Alcohol in Top Videos on TikTok.

J Stud Alcohol Drugs 2021 Sep;82(5):615-622

Department of Health & Kinesiology, Texas A&M University, College Station, Texas.

Objective: The purpose of this study was to characterize the content and themes present in user-generated TikTok videos portraying alcohol.

Method: We captured the 100 most popular videos including the #alcohol hashtag on the popular social networking site TikTok. We used an iterative process to codebook development, resulting in codes for user sentiment toward alcohol, type of alcohol depicted, brand references, degree of alcohol use, and positive/negative associations with alcohol use. Read More

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September 2021

Alcohol Advertising Regulation for the Adult Population: An Analysis of Distilled Spirits Radio Endorsements in Spain.

J Stud Alcohol Drugs 2021 Sep;82(5):610-614

Department of Communication Sciences and Sociology, Universidad Rey Juan Carlos, Camino del Molino s/n, Fuenlabrada (Madrid), Spain.

Objective: Restrictions on advertising of high-alcohol-content beverages aims to prevent consumption in young people and alcohol misuse in adults. The main objective of this research was to analyze the presence of distilled spirits mentions and its compliance with legislation in relation to the minor protection time slot, the factors associated with drinking, and the promotion of excessive consumption.

Method: We conducted a content analysis of all advertising mentioning spirits broadcast throughout 2017 on news/talk radio stations targeting an adult audience in Spain. Read More

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September 2021

What Proportion of On-Trade Alcohol Is Served to Those Who Are Already Potentially Intoxicated? An Analysis of Event-Level Data.

J Stud Alcohol Drugs 2021 Sep;82(5):602-609

School of Health and Related Research (ScHARR), University of Sheffield, Sheffield, England.

Objective: Overservice (i.e., venues serving alcohol to intoxicated drinkers) is a major contributor to alcohol-related harm. Read More

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September 2021

The Combined Effects of Alcohol and Benzodiazepines on Driving-Related Neurocognitive Skills: A Systematic Review.

J Stud Alcohol Drugs 2021 Sep;82(5):553-563

Centre for Human Psychopharmacology, Swinburne University of Technology, Hawthorn, Australia.

Objective: Research concerning the combined effects of alcohol and benzodiazepines on driving-related skills is largely inconsistent. Because as many as 88% of benzodiazepine users report the additional consumption of alcohol, this review aims to provide an updated and concise synthesis of the available high-quality research.

Method: We searched EBSCOhost, PubMed, Scopus, and Web of Science until April 1, 2020, for double-blind, placebo-controlled, repeated-measures intervention trials that examined the effects of alcohol (any dose provided as blood alcohol concentration [BAC]) in combination with oral benzodiazepines on neurocognitive tasks related to driving. Read More

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September 2021

Ubiquilin 1 suppresses the cancer stem cell-like traits of non-small cell lung cancer cells by regulating reactive oxygen species homeostasis.

Bioengineered 2021 Dec;12(1):7143-7155

Department of Geriatric Medicine, Ningbo First Hospital, Ningbo, China.

Cancer stem cell (CSC) has been confirmed to trigger tumor occurrence and progression and CSC can develop strategies to maintain a lower reactive oxygen species (ROS) level compared to cancer cells. However, the mechanisms contributing to ROS homeostasis in CSC are still lacking key elements. In the current study, we found that reductive redox states and ROS levels were suppressed in non-adherent spheres formed by non-small cell lung cancer (NSCLC) cells, which were confirmed to hold CSC-like traits. Read More

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December 2021

Preparations of exploration of immediate hypersensitivity to antineoplastic agents: An oncology pharmacy perspective.

J Oncol Pharm Pract 2021 Sep 21:10781552211035695. Epub 2021 Sep 21.

Groupement Hospitalier Sud, Clinical Oncology Pharmacy Department, 26900Hospices Civils de Lyon, France.

Background: Cancer patients are being exposed to antineoplastic drugs more frequently and for longer periods, resulting in a higher risk of hypersensitivity reactions. The aim of this study was to assess the pharmaceutical time and direct cost of drug allergy explorations following immediate hypersensitivity reactions to antineoplastic agents.

Methods: A micro-costing method was used to collect data on consumption of human and material resources for allergy exploration preparations. Read More

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September 2021

Healthcare utilization and costs associated with persistent post-concussive symptoms.

Brain Inj 2021 Sep 21:1-8. Epub 2021 Sep 21.

Bloorview Research Institute, Holland Bloorview Kids Rehabilitation Hospital, Toronto, Ontario, Canada.

Objective: To describe the healthcare utilization and costs associated with the interdisciplinary treatment of pediatric persistent post-concussive symptoms (PPCS).

Methods: A retrospective chart review was conducted with 461 youth referred by community physicians to an interdisciplinary pediatric PPCS outpatient clinic in Ontario, Canada. Healthcare utilization parameters included accessibility, continuity, comprehensiveness, and service productivity. Read More

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September 2021