Neuropharmacology 2021 02 16;183:108406. Epub 2020 Nov 16.
Department of Biological Regulation, The Weizmann Institute of Science, Rehovot, 7610001, Israel; Department of Pharmacology, Biomedical Science Institute, University of São Paulo, 05508-000, São Paulo, SP, Brazil. Electronic address:
Hemopressin (PVNFKFLSH in rats, and PVNFKLLSH in humans and mice), a fragment derived from the α-chain of hemoglobin, was the first peptide described to have type 1 cannabinoid receptor activity. While hemopressin was shown to have inverse agonist/antagonistic activity, extended forms of hemopressin (i.e. Read More