68,903 results match your criteria consideration interventional

Poor Bone Quality, Multilevel Surgery, and Narrow and Tall Cages Are Associated with Intraoperative Endplate Injuries and Late-onset Cage Subsidence in Lateral Lumbar Interbody Fusion: A Systematic Review.

Clin Orthop Relat Res 2021 Jul 29. Epub 2021 Jul 29.

Department of Orthopaedics and Traumatology, The University of Hong Kong, Hong Kong SAR, China.

Background: A major complication of lateral lumbar interbody fusion (LLIF) is cage subsidence, which may lead to clinical problems, including loss of disc height correction, altered spinal alignment, recurrent pain, and vertebral body fracture. A thorough review of the current knowledge about the risk factors for the two types of cage subsidence after LLIF-intraoperative endplate injury and late-onset cage subsidence-could bring attention to well-established risk factors for clinical consideration while identifying any incompletely characterized factors that require further research to clarify.

Questions/purposes: We performed a systematic review to answer the following questions: (1) Are bone quality and surrogates for bone quality, such as patient age and sex, associated with an increased likelihood of cage subsidence? (2) Are implant-related factors associated with an increased likelihood of cage subsidence?

Methods: Two independent reviewers comprehensively searched Medline, Embase, Cochrane Library, PubMed, and Web of Science from 1997 to 2020 to identify all potential risk factors for cage subsidence after LLIF. Read More

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Predictive value of sagittal craniocervical roentgenographic parameters for HRQOL after craniocervical fusion.

Eur J Orthop Surg Traumatol 2021 Jul 29. Epub 2021 Jul 29.

Orthopedic Department, General Hospital "Agios Andreas", Patras, Greece.

Purpose: Loss of "physiological" sagittal alignment following craniocervical fusion (CCF) for degenerative disease may be associated with loss of horizontal gaze, dysphagia and poor HRQOL. This study reports on sagittal craniocervical roentgenographic predictors of HRQOL (SF-36) in patients following uncomplicated CCF for fresh upper cervical traumatic (UCT) injuries.

Methods: Twenty-two consecutive adult patients (group P) aged 50 ± 16 years, who had undergone CCF for fresh unstable C and CAO/type UCT injuries, were evaluated 39 ± 12 months postoperatively with upright lateral cervical roentgenograms and SF-36as HRQOL measure. Read More

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Simultaneous decontamination of multi-pollutants: A promising approach for water remediation.

Chemosphere 2021 Jun 23;284:131270. Epub 2021 Jun 23.

National Engineering Research Center of Industry Crystallization Technology, School of Chemical Engineering and Technology, Tianjin University, Tianjin, 300072, China; Co-Innovation Center of Chemical Science and Engineering, Tianjin, 300072, China; State Key Laboratory of Chemical Engineering, Zhejiang University, Hangzhou, China. Electronic address:

Water remediation techniques have been extensively investigated due to the increasing threats of soluble pollutants posed on the human health, ecology and sustainability. Confronted with the complex composition matrix of wastewater, the simultaneous elimination of coexisting multi-pollutants remains a great challenge due to their different physicochemical properties. By integrating multi-contaminants elimination processes into one unit operation, simultaneous decontamination attracted more and more attention under the consideration of versatile applications and economical benefits. Read More

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Utilizing Multidisciplinary Medicine in Pain Management: A Narrative Review.

Pain Physician 2021 Aug;24(5):369-378

Department of Behavioral Sciences and Social Medicine, Florida State University; Center for Behavioral Health Integration, Florida State University.

Background: The role of psychological factors influencing chronic pain has been well documented. This review includes a historical perspective and current examination of the literature on psychological and behavioral health characteristics and their influence on chronic pain.

Objectives: To identify psychological and behavioral health factors involved with chronic pain, as well as the challenges and opportunities of integrating multidisciplinary care into a pain management practice. Read More

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The Evaluation Of Urinary Incontinence In Secondary School Children And Risk Factors: A Epidemiological Study.

Int J Clin Pract 2021 Jul 29:e14657. Epub 2021 Jul 29.

Departments of Paediatric Surgery, Osmangazi University, Faculty of Medicine, Eskisehir, Turkey.

Aim: Urinary incontinence is an important problem that can arise due to neurogenic or functional reasons and negatively affect the psychological, social and personality development of children. This study was conducted on secondary school students to determine the prevalence and risk factors of urinary incontinence at night and/or in the daytime.

Methods: The study universe included all secondary school students attending public elementary schools in the city center of Eskişehir (N=34. Read More

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Assessment of frailty and outcome of an ethnogeriatric population in periurban slums of Delhi, India - An interventional strategy in a primary health care setting.

J Family Med Prim Care 2021 Jun 2;10(6):2272-2278. Epub 2021 Jul 2.

HIMSR Jamia Hamdard, New Delhi, India.

Introduction: The burden of frailty and aging will have a profound impact on the economy along with the deteriorating clinical condition of the olds.

Aim: This study aim was to assess frailty of an ethnogeriatric cohort and associate it with domains of quality of life in Delhi along with a follow-up outcome assessment.

Method: Edmonton frail scale on an ethnogeriatric cohort of 200 individuals in periurban slums of Delhi was used and associated with quality of life, calculated by the WHO-BREF -QOL questionnaire. Read More

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Distinct Patterns of Dental Age and Chronological Age: Longitudinal Evaluation of Individuals Born with or without Oral Clefts.

J Dent Child (Chic) 2021 May;88(2):114-119

Dr. Vieira is a professor, Department of Oral Biology, School of Dental Medicine, University of Pittsburgh, Pittsburgh, Pa., USA;, Email:

Dental development is delayed in individuals born with oral clefts. The purpose of this study was to determine: (1) the proportion of individuals with severe delays in dental maturation; and (2) if there are different patterns of dental development timing, taking into consideration the chronological age of the individual.
Dental maturation was estimated by the Demirjian method in children aged seven to 12 years with and without clefts. Read More

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Hepatic inflammatory pseudotumor-like follicular dendritic cell tumor: a case report.

J Med Case Rep 2021 Jul 29;15(1):410. Epub 2021 Jul 29.

Department of Interventional Radiology, "Carol Davila" Central Military Emergency University Hospital, Mircea Vulcanescu Street, no.88, 010825, Bucharest, Romania.

Background: Inflammatory pseudotumor-like follicular dendritic cell sarcoma is a rare histological variant of follicular dendritic cell sarcoma involving typically the spleen and the liver, often linked to the presence of Epstein-Barr virus infection. Definite diagnosis of this type of sarcoma is difficult to make owing to nonspecific clinical and imaging findings and is based on histopathological features. Inflammatory pseudotumor-like follicular dendritic cell sarcoma is described as a low-aggressivity tumor with a favorable prognosis. Read More

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The Association between the Use of Dietary Supplement and Psychological Status of Cancer Survivors in Korea: A Cross-Sectional Study.

Korean J Fam Med 2021 Jul 20;42(4):317-326. Epub 2021 Jul 20.

Department of Family Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea.

Background: Dietary supplements (DS) use is known to be common among cancer survivors. However, detailed information on the factors influencing DS use seems insufficient, including cancer-related and psychological factors.

Methods: Study subjects were 1,852 Korean adult cancer survivors recruited from cancer survivor clinic of two university-affiliated hospitals. Read More

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Intraoperative Measures to Reduce the Risk of COVID-19 Transmission During Minimally Invasive Procedures: A Systematic Review and Critical Appraisal of Societies' Recommendations.

Surg Laparosc Endosc Percutan Tech 2021 Jul 28. Epub 2021 Jul 28.

Medical Affairs, Ethicon Inc., Cincinnati, OH.

Background: The coronavirus 2019 pandemic and the hypothetical risk of virus transmission through aerosolized CO2 or surgical smoke produced during minimally invasive surgery (MIS) procedures have prompted societies to issue recommendations on measures to reduce this risk. The aim of this systematic review is to identify, summarize and critically appraise recommendations from surgical societies on intraoperative measures to reduce the risk of severe acute respiratory syndrome coronavirus 2 transmission to the operative room (OR) staff during MIS.

Methods: Medline, Embase, and Google Scholar databases were searched using a search strategy or free terms. Read More

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Caregiver Perspectives on a Child's Diagnosis of 3q29 Deletion: "We Can't Just Wish This Thing Away".

J Dev Behav Pediatr 2021 Jul 27. Epub 2021 Jul 27.

Department of Human Genetics, Emory University School of Medicine, Atlanta GA; Ms. Glassford is now with the Department of Pediatric Genetics, University of Michigan, Ann Arbor, MI; Ms. Pass is now with the Anderson Cancer Center, University of Texas, Houston, TX; Department of Cell Biology, Emory University School of Medicine, Atlanta, GA; Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta GA.

Objective: Genetic diagnoses are increasingly common in cases of intellectual disability and developmental delay. Although ascertainment of a relatively common, well-studied variant may provide guidance related to treatments and developmental expectations, it is less clear how the diagnosis of a rare variant affects caregivers, especially when the phenotype may include later-onset manifestations such as psychosis. In this study, we sought to identify caregiver concerns in the first qualitative study to assess the psychosocial impact of diagnosis on caregivers of individuals with 3q29 deletion syndrome (3q29Del), which is associated with a 40-fold increase in risk for psychosis. Read More

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Prevalence of Renal Impairment in a US Commercially Insured Rheumatoid Arthritis Population: A Retrospective Analysis.

Rheumatol Ther 2021 Jul 28. Epub 2021 Jul 28.

Division of Clinical Immunology and Rheumatology, University of Alabama at Birmingham, Birmingham, AL, USA.

Introduction: Global prevalence estimates for chronic kidney disease (CKD) in rheumatoid arthritis (RA) vary. This study assessed real-world prevalence estimates of renal impairment, based on estimated glomerular filtration rate (eGFR), among commercially insured patients with RA in the United States (US).

Methods: In this retrospective cohort study, we used administrative claims data from the HealthCore Integrated Research Database (HIRD) between January 2013 and December 2018. Read More

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Improvement in Breast Reconstruction Disparities following Medicaid Expansion under the Affordable Care Act.

Ann Surg Oncol 2021 Jul 28. Epub 2021 Jul 28.

Loma Linda University Health, Loma Linda, CA, USA.

Background:  Under the Affordable Care Act, Medicaid expansion effective 1 January 2014 aimed to increase access to health care. We sought to determine the association of Medicaid expansion with disparities in utilization of breast reconstruction.

Methods: Non-Hispanic Black (NHB) and White (NHW) breast cancer patients undergoing mastectomy +/- reconstruction between 2010 and 2017 were selected from the National Cancer Database. Read More

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Ethical issues in participatory arts methods for young people with adverse childhood experiences.

Health Expect 2021 Jul 27. Epub 2021 Jul 27.

Department of Psychiatry, University of Oxford, Oxford, UK.

Context: Participatory arts-based methods such as photovoice, drama and music have increasingly been used to engage young people who are exposed to psychosocial risks. These methods have the potential to empower youth and provide them with an accessible and welcoming environment to express and manage difficult feelings and experiences. These effects are, however, dependent on the way these methods are implemented and how potential ethical concerns are handled. Read More

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Determination of Silver Nanoparticle Dose .

NanoImpact 2019 Apr;14:100156

Toxicity Assessment Division, MD B105-04, National Health and Environmental Effects Research Laboratory, Office of Research and Development, USEPA, RTP, NC 27711.

An important issue for interpreting nanomaterial testing is quantifying the dose delivered to target cells. Considerations include the concentration added to the culture, the proportion of the applied dose that interacts with the target cells, and the amount that is eventually absorbed by the target cells. Rapid and efficient techniques are needed to determine delivered doses. Read More

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An Economic Analysis of the Impact of Homecare Drug Administration for Biologic Interventions Available for Plaque Psoriasis in the UK.

Dermatol Ther (Heidelb) 2021 Jul 23:1-8. Epub 2021 Jul 23.

York Health Economics Consortium, York, UK.

Introduction: In the UK, biologic interventions for plaque psoriasis can either be administered in a hospital setting or following delivery to a patient's home. To date, limited research has been undertaken on how the administration route affects the overall treatment costs and the implications for this on UK clinical practice. The objective was to explore the cost implications of different administration routes for plaque psoriasis biologic interventions in the UK. Read More

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Time series data analysis and ARIMA modeling to forecast the short-term trajectory of the acceleration of fatalities in Brazil caused by the corona virus (COVID-19).

PeerJ 2021 15;9:e11748. Epub 2021 Jul 15.

Department of Mathematics and Statistics, Faculty of Science and Technology, University of the West Indies St. Augustine, Port of Spain, Trinidad and Tobago.

Objective: This paper incorporates the concept of acceleration to fatalities caused by the coronavirus in Brazil from time series data beginning on 17 March 2020 (the day of the first death) to 3 February 2021 to explain the trajectory of the fatalities for the next six months using confirmed infections as the explanatory variable.

Methods: Acceleration of the cases of confirmed infection and fatalities were calculated by using the concept of derivatives. Acceleration of fatality function was then determined from multivariate linear function and calculus chain rule for composite function with confirmed infections as an explanatory variable. Read More

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Prognostic Value of Standard Coronary Computed Tomography Angiography Reporting System (CAD-RADS).

Sedat Altay

Indian J Radiol Imaging 2021 Jan 31;31(1):37-42. Epub 2021 May 31.

Department of Radiology, Izmir Katip Celebi University Ataturk Research and Training Hospital, İzmir, Turkey.

 This study evaluated the clinical prospects of Coronary Artery Disease-Reporting and Data System (CAD-RADS) scoring in coronary computed tomography angiography (CTA). The aim of the study was to determine the guidance value of CAD-RADS scoring in patient follow-up after CTA.  Reports of cases reported between 2010 and 2013 were reevaluated with CAD-RADS scoring. Read More

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January 2021

'Function First': how to promote physical activity and physical function in people with long-term conditions managed in primary care? A study combining realist and co-design methods.

BMJ Open 2021 Jul 27;11(7):e046751. Epub 2021 Jul 27.

Department of Primary Care and Mental Health, University of Liverpool, Liverpool, UK.

Objectives: To develop a taxonomy of interventions and a programme theory explaining how interventions improve physical activity and function in people with long-term conditions managed in primary care. To co-design a prototype intervention informed by the programme theory.

Design: Realist synthesis combining evidence from a wide range of rich and relevant literature with stakeholder views. Read More

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Vaginal misoprostol versus intracervical Foley catheter for cervical ripening in postdate primigravid women: a randomized clinical trial.

BMC Pregnancy Childbirth 2021 Jul 27;21(1):533. Epub 2021 Jul 27.

The Persian Gulf Tropical Medicine Research Center, The Persian Gulf Biomedical Sciences Research Institute, Bushehr University of Medical Sciences, Bushehr, Iran.

Background: Being one of the most common indications of labor induction, postdate pregnancy can lead to serious maternal and fetal complications. In this study we aimed to compare vaginal misoprostol with intracervical Foley catheter (FC) for cervical ripening in postdate primigravid women.

Methods: This randomized clinical trial included 120 primigravid women aged 18-35 years with singleton,  postdate pregnancies, and Bishop score ≤ 4. Read More

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Potential for optimizing management of obesity in the secondary prevention of coronary heart disease.

Eur Heart J Qual Care Clin Outcomes 2021 Jul 27. Epub 2021 Jul 27.

Department of Medicine, Solna, Karolinska Institutet, FoU - Tema Hjärta och Kärl, S1:02, Karolinska Universitetssjukhuset/Solna, SE-171 76, Stockholm, Sweden.

Aims: Prevention guidelines have identified the management of obese patients as an important priority to reduce the burden of incident and recurrent cardiovascular disease. Still, studies have demonstrated that over 80% of patients with coronary heart disease (CHD) fail to achieve their weight target. Here, we describe advice received and actions reported by overweight CHD patients since being discharged from hospital and how weight changes relate to their risk profile. Read More

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Questionnaires used in complex trauma intervention evaluations and consideration of their utility for autistic adults with mild intellectual disability: A systematic review.

Res Dev Disabil 2021 Jul 24;117:104039. Epub 2021 Jul 24.

Population Health Sciences Institute, Faculty of Medical Sciences, Newcastle University, NE1 4LP, United Kingdom.

Introduction: Research suggests some trauma symptoms e.g. avoidance are difficult to recognise in autistic people with intellectual disability while arousal/emotional and interpersonal difficulties may be useful signals. Read More

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Electrogram-guided Endomyocardial Biopsy Yield in Patients with Suspected Cardiac Sarcoidosis and Relation to Outcomes.

J Cardiovasc Electrophysiol 2021 Jul 27. Epub 2021 Jul 27.

Department of Cardiovascular Medicine, Mayo Clinic College of Medicine, Rochester, MN, USA.

Objective: Endomyocardial biopsy (EMB) is a useful diagnostic tool though the yield may be limited in many myocardial diseases. Data on the diagnostic yield and prognostic significance of EMB guided by abnormal electrograms (EGM-Bx) in suspected cardiac sarcoidosis (CS) are scarce.

Methods: Seventy-nine patients (mean age 56±12 years; 61% men) with suspected CS based on clinical and imaging features underwent right or left ventricular EGM-Bx guided by electroanatomic mapping. Read More

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A Comparative Analysis of Drug Therapy, Disease Phenotype, and Health Care Outcomes for Men and Women with Inflammatory Bowel Disease.

Dig Dis Sci 2021 Jul 27. Epub 2021 Jul 27.

Division of Clinical Pharmacology, Department of Medicine, Western University, 339 Windermere Road A10-221a, London, ON, N6A 5A5, Canada.

Background: Sex and gender refer to biological and social differences between men and women. While well-evaluated in other disciplines, their roles in inflammatory bowel disease (IBD) are not well-defined. This study aimed to characterize differences in healthcare outcomes in men and women with IBD. Read More

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Individual- and Institutional-level Concerns of Health Care Workers in Canada During the COVID-19 Pandemic: A Qualitative Analysis.

JAMA Netw Open 2021 Jul 1;4(7):e2118425. Epub 2021 Jul 1.

University Health Network, Toronto, Ontario, Canada.

Importance: Mental health and coping difficulties among health care workers (HCWs) have been reported during pandemics and particularly during the COVID-19 pandemic.

Objective: To examine sources of distress and concern for HCWs in Canada during the COVID-19 pandemic.

Design, Setting, And Participants: In this qualitative study, a critical discourse analysis was performed of questions posed by HCWs to hospital senior leadership between March 16, 2020, and December 1, 2020, through an online employee forum as part of a larger mixed-methods evaluation of a stepped-care mental health support program for HCWs at 1 of Canada's largest health care institutions. Read More

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Anterior and antero-lateral mini-invasive approaches for primary total hip replacement.

Acta Biomed 2021 Jul 26;92(S3):e2021014. Epub 2021 Jul 26.

ISS San Marino.

Background And Aim Of The Work: the literature provides conflicting data regarding the various approaches for hip prosthetic surgery. This study analysed our case series on the anterior and anterolateral minimally invasive approaches, trying to define the indications, complications, the technical tips, the advantages and disadvantages.

Methods: from 2011 to 2019 we performed 1227 interventions of which 1020 had a regular follow-up, up to an average period of 5. Read More

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CHECK UP: A student-designed model for creating innovative patient education materials that your patients will actually use.

Int J Psychiatry Med 2021 Jul 27:912174211035214. Epub 2021 Jul 27.

Department of Family & Community Medicine, Medical College of Wisconsin, Milwaukee, WI, USA.

Objective: As appointments become more rushed, it is crucial that primary care clinicians consider new and effective ways to provide preventive health education to patients. Currently, patient education is often handouts printed from the electronic medical record system; however, these pieces of paper often do not have the desired impact. Well-established advertising methods reveal that repeated exposure is key in recall and swaying consumer decisions. Read More

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Systematic review: duodenogastroesophageal (biliary) reflux prevalence, symptoms, oesophageal lesions and treatment.

Aliment Pharmacol Ther 2021 Jul 27. Epub 2021 Jul 27.

Department of Chronic Diseases, Metabolism and Ageing (ChroMetA), Translational Research Center for Gastrointestinal Disorders (TARGID), Katholieke Universiteit Leuven, Leuven, Belgium.

Background: The prevalence of duodenogastroesophageal reflux (DGER) and its effect on symptoms and oesophageal lesions in gastroesophageal reflux disease (GERD) is unclear.

Aims: To conduct a systematic review to determine the prevalence of DGER among patients with GERD, the effect of DGER on symptoms and oesophageal lesions, and the treatment of DGER.

Methods: We searched Pubmed and MEDLINE for full text, English language articles until October 2020 that evaluated DGER prevalence among patients with GERD, the effect of DGER on symptoms and oesophageal lesions, and the treatment of DGER. Read More

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Implementation of a real-time, ultrasound-guided prostate HDR brachytherapy program.

J Appl Clin Med Phys 2021 Jul 26. Epub 2021 Jul 26.

Department of Radiation Oncology, University of Iowa, Iowa City, IA, USA.

This work presents a comprehensive commissioning and workflow development process of a real-time, ultrasound (US) image-guided treatment planning system (TPS), a stepper and a US unit. To adequately benchmark the system, commissioning tasks were separated into (1) US imaging, (2) stepper mechanical, and (3) treatment planning aspects. Quality assurance US imaging measurements were performed following the AAPM TG-128 and GEC-ESTRO recommendations and consisted of benchmarking the spatial resolution, accuracy, and low-contrast detectability. Read More

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Do ethnic patients report longer lung cancer intervals than Anglo-Australian patients?: Findings from a prospective, observational cohort study.

Eur J Cancer Care (Engl) 2021 Jul 26:e13492. Epub 2021 Jul 26.

Department of General Practice and Centre for Cancer Research, Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, Melbourne, Victoria, Australia.

Objective: Lung cancer patients from ethnic minorities have poorer outcomes than their Caucasian counterparts. We compared lung cancer intervals between culturally and linguistically diverse (CALD) and Anglo-Australian patients to identify ethnic disparities.

Methods: This was a prospective, observational cohort study comprising a patient survey and reviews of patients' hospital and general practice records. Read More

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