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Root Fracture and Extrusive Luxation in Primary Teeth and Their Management: A Case Report.

Dent J (Basel) 2021 Sep 11;9(9). Epub 2021 Sep 11.

Department of Oral and Maxillofacial Science, "Sapienza" University of Rome, Via Caserta, 6, 00161 Rome, Italy.

Background: Extrusion, lateral luxation, and intrusion are among the most serious types of dental trauma. Only a few studies have specifically focused on extrusion; the present one was aimed at reporting a case of domestic traumatic dental injury to primary tooth and describing the measures taken in managing the trauma in order to avoid future consequences to the underlying permanent tooth germ.

Case Report: A 3. Read More

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September 2021

Assessment of Oxygen Expansion during Internal Bleaching with Enamel and Dentin: A Comparative In Vitro Study.

Dent J (Basel) 2021 Aug 24;9(9). Epub 2021 Aug 24.

Department of Endodontics and Restorative Dentistry, School of Medicine and Dentistry, Catholic University of Valencia, Quevedo 2, 46001 Valencia, Spain.

Internal bleaching is a conservative, non-invasive, and simple treatment that is frequently performed in daily clinical practice. The present in vitro study analyzes the oxygen expansion of different bleaching agents resulting from the oxidation reaction when interacting with enamel and dentin. Enamel and dentin were crushed separately until obtaining a fine powder with particles of an approximate size between 0. Read More

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Drp1-dependent mitochondrial fission mediates corneal injury induced by alkali burn.

Free Radic Biol Med 2021 Sep 22. Epub 2021 Sep 22.

Institute of Geriatrics, Affiliated People's Hospital of Nanchang University, Nanchang, Jiangxi, 330006, PR China; Department of Neurology, Affiliated People's Hospital of Nanchang University, Nanchang, Jiangxi, 330006, PR China. Electronic address:

Corneal alkali burn, as one of the most serious ophthalmic emergencies, is difficult to be cured by conservative treatments. It is well known that oxidative stress, inflammation, and neovascularization are the main causes of corneal damage after alkali burn, but its underlying mechanism remains to be elucidated. Here, we reported that the expression and phosphorylation (Ser616) of mitochondrial fission protein Drp1 were up-regulated at day 3 after alkali burn, while mitochondrial fusion protein Mfn2 was down-regulated. Read More

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September 2021

Evaluation of ozone therapy in endodontic treatment of teeth with necrotic pulp and apical periodontitis: A randomized clinical trial.

J Endod 2021 Sep 22. Epub 2021 Sep 22.

Department of Prosthodontics, Pacific Dental college and hospital, Udaipur, Rajasthan, India.

Aim: To compare the effect of different application techniques of ozone on the prevalence of post endodontic pain in patients undergoing single-visit root canal treatment.

Materials And Methods: A hundred and eight patients with necrotic pulp in single-rooted teeth and apical periodontitis participated in the trial. Standard single visit endodontics (SVE) protocol was followed with 5. Read More

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September 2021

An in-home rehabilitation program for the treatment of urinary incontinence symptoms in endometrial cancer survivors: a single-case experimental design study.

Int Urogynecol J 2021 Sep 25. Epub 2021 Sep 25.

Rehabilitation Department, Faculty of Medicine, Université Laval, Québec, Québec, Canada.

Introduction And Hypothesis: There is a high prevalence of urinary incontinence among endometrial cancer survivors. They are also known to present with pelvic floor muscle alterations. Evidence on the effects of conservative interventions for the management of UI is scarce. Read More

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September 2021

Short- and long-term follow-up of patients with non-neoplastic esophageal perforation.

Langenbecks Arch Surg 2021 Sep 25. Epub 2021 Sep 25.

Department of General, Visceral, Cancer and Transplantation Surgery, University of Cologne, Kerpener Str. 62, 50937, Cologne, Germany.

Purpose: Esophageal perforation is associated with high morbidity and mortality. In addition to surgical treatment, endoscopic endoluminal stent placement and endoscopic vacuum therapy (EVT) are established methods in the management of this emergency condition. Although health-related quality of life (HRQoL) is becoming a major issue in the evaluation of any therapeutic intervention, not much is known about HRQoL, particularly in the long-term follow-up of patients treated for non-neoplastic esophageal perforation with different treatment strategies. Read More

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September 2021

Management of the patient with the open abdomen.

Curr Opin Crit Care 2021 Sep 24. Epub 2021 Sep 24.

Surgical Intensive Care Unit, Shaare Zedek Medical Center and Hebrew University Faculty of Medicine General Intensive Care Unit, Shaare Zedek Medical Center, Jerusalem Intensive Care Unit, Barzilai Medical Center, Ashkelon, Israel Division of Thoracic Surgery, McGill University Health Centre, Montreal, Quebec, Canada Aix Marseille Université, Assistance Publique Hôpitaux Universitaire de Marseille, Department of Anesthesiology and Intensive Care Unit, Nord Hospital, Marseille, France.

Purpose Of Review: The aim of this study was to outline the management of the patient with the open abdomen.

Recent Findings: An open abdomen approach is used after damage control laparotomy, to decrease risk for postsurgery intra-abdominal hypertension, if reoperation is likely and after primary abdominal decompression.Temporary abdominal wall closure without negative pressure is associated with higher rates of intra-abdominal infection and evisceration. Read More

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September 2021

Charcot arthropathy in the spine. Experience in our centre. About 13 cases. Review of the literature.

Rev Esp Cir Ortop Traumatol 2021 Sep 21. Epub 2021 Sep 21.

Hospital Universitario Doctor Peset de Valencia, Valencia, España.

Charcot arthropathy of the spine is a neuropathic affectation of the spine, it is considered rare, has a destructive and progressive evolution. It is usually due to a previous traumatic injury, but it has also been described as secondary to other infectious or tumoural processes. Initially, surgical treatment has always been considered for possible complications such as pain control and trunk instability. Read More

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September 2021

Current Evidence and Future Perspectives in the Management of Nonmetastatic Upper Tract Urothelial Carcinoma.

Eur Urol Oncol 2021 Sep 21. Epub 2021 Sep 21.

Urology, GRC n°5, Predictive Onco-Urology, AP-HP, Hôpital Pitié-Salpêtrière, Sorbonne University, Paris, France. Electronic address:

This case-based discussion describes the management of a 66-yr-old man who presented to the emergency department with gross hematuria. His urine cytology was benign, and computed tomography (CT) with nephrographic phase revealed a 2.5 cm filling defect within the left renal pelvis and luminal narrowing in the right proximal ureter with hydronephrosis. Read More

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September 2021

A Nomogram for the Prediction of Intermediate Significant Renal Function Loss After Robot-assisted Partial Nephrectomy for Localized Renal Tumors: A Prospective Multicenter Observational Study (RECORd2 Project).

Eur Urol Focus 2021 Sep 21. Epub 2021 Sep 21.

Department of Urology, Unit of Oncologic Minimally-Invasive Urology and Andrology, Careggi Hospital, University of Florence, Florence, Italy. Electronic address:

Background: Robot-assisted partial nephrectomy (RAPN) is increasingly adopted for the treatment of localized renal tumors; however, rates and predictors of significant renal function (RF) loss after RAPN are still poorly investigated, especially at a long-term evaluation.

Objective: To analyze the predictive factors and develop a clinical nomogram for predicting the likelihood of ultimate RF loss after RAPN.

Design, Setting, And Participants: We prospectively evaluated all patients treated with RAPN in a multicenter series (RECORd2 project). Read More

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September 2021

Biliary peritonitis after endoscopic retrograde cholangiopancreatography.

J Visc Surg 2021 Sep 21. Epub 2021 Sep 21.

Department of digestive surgery, HIA Bégin, 69, avenue de Paris, 94160 Saint-Mandé, France; Val de Grâce School, 1, place Alphonse-Laveran, 75230 Paris cedex 05, France. Electronic address:

Occurrence of a perforation after endoscopic CPRE sphincterotomy is a complication previously reported in the literature, with frequent repercussions on the duodenum and the periampullary region (Stapfer types 1 and 2); treatment modalities are strictly codified. During an endoscopic procedure, it may be associated with manipulation of a guide wire, generally leading to isolated pneumoretroperitoneum (Stapfer type 4), which is conservatively treated. Secondarily to endoscopic maneuvers, Stapfer type 3 may also occur, causing pancreatic or biliary ductal lesions. Read More

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September 2021

Anomalous insertion of anterior and posterior horns of medial meniscus. Case report.

BMC Musculoskelet Disord 2021 Sep 24;22(1):823. Epub 2021 Sep 24.

Orthopaedic and Trauma Department, Campus Bio-Medico University of Rome, Rome, Italy.

Background: Anatomical variations of the attachment of medial meniscus are a common finding. However, anomalies of the posterior horn are extremely rare. Only two cases of posterior root anomaly have been described prior to the routine use of arthroscopy for evaluation and treatment of meniscal pathology. Read More

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September 2021

The RPOC long axis is a simple indicator for predicting the need of invasive strategies for secondary postpartum hemorrhage in either post-abortion or post-partum women: a retrospective case control study.

BMC Pregnancy Childbirth 2021 Sep 24;21(1):653. Epub 2021 Sep 24.

Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.

Background: The retained products of conception (RPOC) and related conditions (RPOC-ARC) are the main cause of secondary postpartum hemorrhage (sPPH), but there is no clear consensus for their management. The purpose of this study was to characterize those RPOC-ARC that require invasive treatment and those that could be managed more conservatively.

Methods: We retrospectively analyzed 96 cases of RPOC-ARC that occurred after miscarriage, abortion, or delivery at a gestational age between 12 and 42 completed weeks, that were managed within our institution from May 2015 to August 2020. Read More

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September 2021

Cervical adenocarcinoma in situ during pregnancy and subsequent fertility-sparing therapy challenge.

Int J Gynaecol Obstet 2021 Sep 24. Epub 2021 Sep 24.

Department of Obstetrics and Gynecology, Infanta Sofía University Hospital, San Sebastián de los Reyes, Madrid, Spain.

Objective: Adenocarcinoma in situ (AIS) of the cervix is a premalignant lesion, precursor of invasive disease. It is less frequent than its squamous counterpart. During pregnancy, AIS is a scarcely described scenario, whose diagnosis barely differs from non-pregnant patients. Read More

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September 2021

Are open surgery and total resection good choices for traumatic myositis ossificans in children?

Int Orthop 2021 Sep 24. Epub 2021 Sep 24.

Orthopedics Department, Chongqing Key Laboratory of Pediatrics, Ministry of Education Key Laboratory of Child Development and Disorders, National Clinical Research Center for Child Health and Disorders, China International Science and Technology Cooperation base of Child development and Critical Disorders, Children's Hospital of Chongqing Medical University, Yuzhong District Zhongshan 2road 136#, Chongqing, 400014, People's Republic of China.

Background: Traumatic myositis ossificans is a self-limited, non-neoplastic, ectopic bone formation in the soft tissues caused by trauma. Conservative treatment is the mainstay of management. However, open surgery and complete resection should be considered in patients with limited joint function and constant pain. Read More

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September 2021

Platelet-rich fibrin for root coverage: A plausible approach in periodontal plastic and esthetic surgery.

Ann Afr Med 2021 Jul-Sep;20(3):241-244

Department of Periodontics, Vyas Dental College and Hospital, Jodhpur, Rajasthan, India.

Predictable esthetic root coverage has evolved into conventional treatment modalities making cosmetic procedures an integral part of periodontal treatment. The advent of second-generation platelet concentrates, i.e. Read More

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September 2021

Grossing and reporting of bone tumor specimens in surgical oncology: Rationale with current evidence and recent updates.

Indian J Cancer 2021 Jul-Sep;58(3):326-335

Jawaharlal Nehru Medical College, Aligarh Muslim University, Aligarh, Uttar Pradesh, India.

Primary bone tumors, including sarcomas, are rare tumors and require a multidisciplinary approach, including inputs from a radiologist, pathologist, medical oncologist, and surgical and radiation oncologist, for optimal management. Over the years, there has been a paradigm shift toward the treatment of bone sarcomas, from radical resections to conservative surgical procedures, to achieve improved clinical and functional outcomes. This has led to receiving and processing various types of specimens in orthopedic oncopathology. Read More

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September 2021

The use of super-selective uterine artery branch embolization and methotrexate in cervical pregnancy - case reports and literature review.

Ann Agric Environ Med 2021 Sep 7;28(3):521-524. Epub 2020 Oct 7.

University of Humanites and Economics, Łódź, Satellite Campus in Warsaw, Poland.

Cervical ectopic pregnancy (CEP) is one of the rarest types of ectopic pregnancy. Early detection of such cases increases the chances of conservative treatment and fertility preservation. Within 6 weeks of each other, 2 women were admitted to the OB/GYN Department with cervical ectopic pregnancies. Read More

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September 2021

Surgical management and oncological outcome of non-squamous cell carcinoma of the larynx: a bicentric study.

Eur Arch Otorhinolaryngol 2021 Sep 24. Epub 2021 Sep 24.

IRCCS Ospedale Policlinico San Martino, Genoa, Italy.

Purpose: Non-squamous cell carcinoma (non-SCC) accounts for about 5% of laryngeal malignancies. Survival data are limited, and consensus on management principles is lacking. The present study reviews our experience in the surgical treatment of non-metastatic non-SCC of the larynx and compares oncological and functional outcomes in a cohort of patients affected by traditional SCC. Read More

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September 2021

State-of-the-art surgery for sigmoid diverticulitis.

Langenbecks Arch Surg 2021 Sep 23. Epub 2021 Sep 23.

Department of Molecular and Translational Medicine, University of Brescia, 25124, Brescia, Italy.

Background: In the last two decades, there has been a Copernican revolution in the decision-making for the treatment of Diverticular Disease.

Purpose: This article provides a report on the state-of-the-art of surgery for sigmoid diverticulitis.

Conclusion: Acute diverticulitis is the most common reason for colonic resection after cancer; in the last decade, the indication for surgical resection has become more and more infrequent also in emergency. Read More

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September 2021

Conservative Treatment for Upper Urinary Tract Urothelial Carcinoma.

Eur Urol Open Sci 2021 Oct 13;32:38-39. Epub 2021 Sep 13.

GRC Urolithiasis no. 20, Sorbonne University, Tenon Hospital, Paris, France.

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October 2021

Trapezium and Bennett Fracture - A Rare Base Thumb Fracture Pattern:A Case Report.

J Orthop Case Rep 2021 May;11(5):99-103

Department of Orthopaedics and Traumatology, Centro Hospitalar Tondela-Viseu, Viseu Dão Lafões, Portugal.

Introduction: Trapezium fracture is a rare entity whose treatment is controversial. The reported cases range from conservative treatment to surgical treatment with good reported results.

Case Report: This paper reports a clinical case of trapezium-metacarpal fracture-dislocation associated with trapezius fracture and Bennett fracture, surgically treated with excellent functional and radiological results. Read More

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Post-traumatic Late Presentation of Morel-Lavallée: Case Report and Review of Literature.

J Orthop Case Rep 2021 May;11(5):92-95

Department of Orthopedic Surgery, Lebanese Military Hospital, Beirut, Lebanon.

Introduction: Morel-Lavallée (MLL) is an uncommon entity that is missed by many physicians, it is the result of a shearing force that leads to degloving of the subcutaneous fat from the underlying deep fascia.

Case Report: We present a case of a 15-year-old male patient who presented 3 months after the initial crush injury with a large MLL lesion at the lateral aspect of the right proximal thigh. He was treated with incision and drainage with compressive dressing and a negative pressure drain. Read More

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Management for Bony Mallet Thumb with a Single Extension Blocking Kirschner Wire.

J Orthop Case Rep 2021 May;11(5):76-79

Department of Orthopaedic Surgery, University Hospital Limerick, St Nessan's Road, Dooradoyle, Co. Limerick, V94 F858, Ireland.

Introduction: Mallet finger injury is defined by disruption of the terminal extensor tendon distal-to-distal interphalangeal (DIP) joint. While in the fingers, it is a relatively common injury, it is a rarely encountered entity when involving the thumb. Various conservative and operative treatment strategies have been reported for the management of mallet thumb with no consensus by clinicians. Read More

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Ruptured Popliteal Cysts Mimicking Deep Vein Thrombosis in Well-Functioning Total Knee Replacements: Report of Two Cases and Review of Literature.

J Orthop Case Rep 2021 May;11(5):18-23

Department of Orthopaedics, Postgraduate Institute of Medical Education and Re-search, Chandigarh India.

Background: Implant wear and loosening with eluding metal/polythene debris are commonly implicated in the occurrence of Baker's cysts in post-operative total knee replacement (TKR) patients, who present with post-operative pain and swelling, mimicking deep venous thrombosis. However, we present two symptomatic cases presenting with ruptured Baker's cysts post-TKRs, with no evidence of implant loosening or wear.

Cases Report: The 1st patient was a 55-year-old male, who underwent TKR for Grade 4 bilateral knee osteoarthritis and presented with acute onset of pain and swelling over the left popliteal fossa, which progressed to involve the calf. Read More

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Ligament reconstruction and tendon interposition in comparison with hematoma distraction arthroplasty for the treatment of arthritis in the trapeziometacarpal joint.

Int J Burns Trauma 2021 15;11(4):296-303. Epub 2021 Aug 15.

Department of Orthopedic Surgery, School of Medicine, Isfahan University of Medical Sciences Isfahan, Iran.

Introduction: Arthritis in trapeziometacarpal joint is one of the most common types of osteoarthritis which do not respond to conservative therapies in progressed cases and require surgical processes. The current study compares the two successful techniques, ligament reconstruction and tendon interposition (LRTI) versus hematoma distraction arthroplasty (HDA).

Methods: The current randomized clinical trial has been conducted on 56 patients with trapeziometacarpal joint osteoarthritis whom were randomly divided into two groups undergone surgical procedures of LTRI (n=28) and HDA (n=28). Read More

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Pulp Stones: Diagnostic Significance in Early Diagnosis and Radiographic Correlation with Ischemic Heart Diseases.

Indian J Radiol Imaging 2021 Apr 22;31(2):277-283. Epub 2021 Jun 22.

Department of Oral Medicine and Radiology, Saraswati Dhanwantari Dental College and Hospital and Post-graduate Research Institute, Parbhani, Maharashtra, India.

Sufficient evidence exists in the literature which indicates that patients with ischemic heart diseases (IHDs) show higher degree of pulp calcifications. The present study was, therefore, planned to estimate the prevalence of pulp stones in patients diagnosed with/or undergoing treatment for IHDs. The present study, which consisted of 300 subjects within the age range of 25 to 65 years, was divided into two groups: study group comprising 150 patients (113 males and 37 females) and 150 age- and sex-matched healthy controls. Read More

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Biofilm formation following chitosan-based varnish or chlorhexidine-fluoride varnish application in patients undergoing fixed orthodontic treatment: a double blinded randomised controlled trial.

BMC Oral Health 2021 Sep 23;21(1):465. Epub 2021 Sep 23.

Faculty of Dentistry, University of Toronto, Toronto, ON, Canada.

Background: Orthodontic treatment poses an increased risk of plaque accumulation and demineralisation of enamel leading to white spot lesion around the brackets. This parallel arm trial aims to assess the degree of bacterial plaque formation adjacent to orthodontic brackets, following the application of a chitosan-based varnish or chlorhexidene-fluoride varnish.

Methods: A total of 200 teeth from 20 patients undergoing fixed orthodontic therapy were assessed and biofilm formation around the brackets were recorded using the Bonded Bracket Index (Plaque index) at baseline and weekly for 6 weeks. Read More

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September 2021

Do Various Treatment Modalities of Vesicoureteral Reflux Have Any Adverse Effects in Pediatric Patients? A Meta-Analysis.

Urol Int 2021 Sep 23:1-9. Epub 2021 Sep 23.

Department of Pediatrics, Peking University First Hospital, Beijing, China.

Purpose: Vesicoureteral reflux (VUR) is a risk factor for various renal problems like recurrent urinary tract infections (UTIs), pyelonephritis, renal scarring, hypertension, and other renal parenchymal defects. The interventions followed by pediatricians include low-dose antibiotic treatment, surgical correction, and endoscopy. This meta-analysis aimed to assess the advantages and drawbacks of various primary VUR treatment options. Read More

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September 2021

Oncoplastic Mammoplasty with disguised geometric compensation.

Surg Oncol 2021 Sep 20;39:101660. Epub 2021 Sep 20.

Gynaecology and Breast Unit, Araujo Jorge Cancer Hospital, ACCG, Goiania, Goias, Brazil; Program of Mastology, Department of Gynaecology and Obstetrics, Federal University of Goiás, Goiania, Goias, Brazil.

Objective: To evaluate the results of a cohort of patients submitted to a new technique of oncoplastic mammoplasty, referred to as Disguised Geometric Compensation Mammoplasty (GCM), which is suitable for tumours involving the glandular tissue in the pillars of the mammoplasty.

Materials And Methods: Twenty-five breast tumours involving the pillars of the mammoplasty were included, 20 (80.0%) invasive ductal carcinomas, 3 (12. Read More

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September 2021